Degeneración y Regeneración del Sistema Nervioso Central

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Lineas de Investigación

01. Estudios experimentales sobre posibles terapias con células madre en el tratamiento de la hidrocefalia feto-neonatal

02. Condicionamiento de la microglía a largo plazo.



Proyectos de Investigación

Terapia celular combinada basada en el uso de células madre no embrionarias humanas para la recuperación de la pared ventricular dañada por hidrocefalia

Universidad de Málaga
. 2019

Evaluación de una innovadora terapia celular para el tratamiento de la hidrocefalia posthemorrágica basada en células madre mesenquimales e inducidas humanas

Junta de Andalucía
. 2019

PI19/00778 Testing non-embryonic based stem cells as regenerative cell sources for treating neonates with intraventricular hemorrhages that develop posthemorrhagic hydrocephalus. IP ANTONIO JESUS JIMENEZ LARA

ISCIII
. 2019

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro
  1. Pereira, R, Alves, C, Aler, M, Amorim, A, Arévalo, C, Betancor, E et al.. A GHEP-ISFG collaborative study on the genetic variation of 38 autosomal indels for human identification in different continental populations. Forensic Sci Int Genet. 2018;32 :18-25. doi: 10.1016/j.fsigen.2017.09.012. PubMed PMID:29024923 .
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  1. Carbonell-Corvillo, P, Tristán-Clavijo, E, Cabrera-Serrano, M, Servián-Morilla, E, García-Martín, G, Villarreal-Pérez, L et al.. A novel MYH7 founder mutation causing Laing distal myopathy in Southern Spain. Neuromuscul. Disord. 2018;28 (10):828-836. doi: 10.1016/j.nmd.2018.07.006. PubMed PMID:30166250 .
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  1. Rubio, L, Sioli, JM, Gaitán, MJ, Martin-de-Las-Heras, S. Dental color measurement to predict DNA concentration in incinerated teeth for human identification. PLoS ONE. 2018;13 (4):e0196305. doi: 10.1371/journal.pone.0196305. PubMed PMID:29698524 PubMed Central PMC5919669.
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  1. Garcia-Martin, G, Serrano-Castro, PJ. [Epidemiology of epilepsy in Spain and Latin America]. Rev Neurol. 2018;67 (7):249-262. . PubMed PMID:30232798 .
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  1. Chamorro-Muñoz, MI, García-Martín, G, Pérez-Errazquin, F, Romero-Acebal, M, García-Rodríguez, A, Gutiérrez-Bedmar, M et al.. Epidemiological study of mortality in epilepsy in a Spanish population. Seizure. 2017;46 :19-23. doi: 10.1016/j.seizure.2017.02.004. PubMed PMID:28214712 .
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  1. Martín-Montañez, E, Millon, C, Boraldi, F, Garcia-Guirado, F, Pedraza, C, Lara, E et al.. IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids. Redox Biol. 2017;13 :69-81. doi: 10.1016/j.redox.2017.05.012. PubMed PMID:28575743 PubMed Central PMC5454142.
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  1. Rivetti di Val Cervo, P, Romanov, RA, Spigolon, G, Masini, D, Martín-Montañez, E, Toledo, EM et al.. Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model. Nat. Biotechnol. 2017;35 (5):444-452. doi: 10.1038/nbt.3835. PubMed PMID:28398344 .
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  1. Blanco, E, Galeano, P, Palomino, A, Pavón, FJ, Rivera, P, Serrano, A et al.. Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. Eur Neuropsychopharmacol. 2016;26 (3):477-92. doi: 10.1016/j.euroneuro.2015.12.040. PubMed PMID:26811312 .
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  1. Órpez-Zafra, T, Pavía, J, Pinto-Medel, MJ, Hurtado-Guerrero, I, Rodriguez-Bada, JL, Martín Montañez, E et al.. Development and validation of an ELISA for quantification of soluble IFN-β receptor: assessment in multiple sclerosis. Bioanalysis. 2015;7 (22):2869-80. doi: 10.4155/bio.15.208. PubMed PMID:26571364 .
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  1. Rivera, P, Blanco, E, Bindila, L, Alen, F, Vargas, A, Rubio, L et al.. Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain. Front Cell Neurosci. 2015;9 :379. doi: 10.3389/fncel.2015.00379. PubMed PMID:26483633 PubMed Central PMC4587308.
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  1. Rubio, L, Sioli, JM, Suarez, J, Gaitan, MJ, Martin-de-las-Heras, S. Spectrophotometric analysis of color changes in teeth incinerated at increasing temperatures. Forensic Sci. Int. 2015;252 :193.e1-6. doi: 10.1016/j.forsciint.2015.04.033. PubMed PMID:25963275 .
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