Degeneración y Regeneración del Sistema Nervioso Central

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Lineas de Investigación

01. Estudios experimentales sobre posibles terapias con células madre en el tratamiento de la hidrocefalia feto-neonatal

02. Condicionamiento de la microglía a largo plazo.



Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro

Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure

Rivera, P; Fernandez-Arjona, MD; Silva-Pena, D; Blanco, E; Vargas, A; Lopez-Avalos, MD; Grondona, JM; Serrano, A; Pavon, FJ; de Fonseca, FR; Suarez, J
Biochemical Pharmacology 2018


Evaluation of the quality of care of elderly patients with chronic and breakthrough pain treated with opioids: SAND study

Rodriguez, MJ; de la Torre, R; Ortega, JL; Trinidad, JM; Benitez, D; Jimenez, AJ; Sanz-Yague, A; Soler, B; Torres, LM
Current Medical Research And Opinion 2018


Stress, Depression, Resilience and Ageing: A Role for the LPA-LPA(1) Pathway

Roman, MF; Sara, T; Estela, CO; Margarita, PM; Guillermo, ET; Fernando, RD; Javier, SL; Carmen, P
Current Neuropharmacology 2018


Effects of genetic deletion versus pharmacological blockade of the LPA(1) receptor on depression-like behaviour and related brain functional activity

Moreno-Fernandez, RD; Nieto-Quero, A; Gomez-Salas, FJ; Chun, J; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Perez-Martin, M; Pedraza, C
Disease Models & Mechanisms 2018


A Simple Endoscopic Score Modified for the Upper Gastrointestinal Tract in Crohn’s Disease [UGI-SES-CD]: A Report From the ImageKids Study

Ledder, O; Church, P; Cytter-Kuint, R; Martinez-Leon, M; Sladek, M; Coppenrath, E; Weiss, B; Yerushalmi, B; de Carpi, JM; Duchano, L; Towbin, A; Assa, A; Shaoul, R; Mearin, ML; Alex, G; Griffiths, A; Tumer, D
Journal Of Crohns & Colitis 2018


A Distinct Metabolite Profile Correlates with Neurodegenerative Conditions and the Severity of Congenital Hydrocephalus.

Garcia-Bonilla, Maria; Garcia-Martin, Maria L; Munoz-Hernandez, M Carmen; Dominguez-Pinos, Dolores; Martinez-Leon, Maria I; Penalver, Ana; Castilla, Laura; Alonso, Francisco J; Marquez, Javier; Shumilov, Kirill; Hidalgo-Sanchez, Ramon; Gutierrez, Antonia; Paez-Gonzalez, Patricia; Jimenez, Antonio J
Journal Of Neuropathology And Experimental Neurology 2018


Expression of a Novel Ciliary Protein, IIIG9, During the Differentiation and Maturation of Ependymal Cells

Cifuentes, M; Baeza, V; Arrabal, PM; Visser, R; Grondona, JM; Saldivia, N; Martinez, F; Nualart, F; Salazar, K
Molecular Neurobiology 2018


SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies

Salazar, K; Martinez, F; Perez-Martin, M; Cifuentes, M; Trigueros, L; Ferrada, L; Espinoza, F; Saldivia, N; Bertinat, R; Forman, K; Oviedo, MJ; Lopez-Gambero, AJ; Bonansco, C; Bongarzone, ER; Nualart, F
Molecular Neurobiology 2018

maLPA1-null mice as an endophenotype of anxious depression

Moreno-Fernandez, RD; Perez-Martin, M; Castilla-Ortega, E; del Valle, CR; Garcia-Fernandez, MI; Chun, J; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Pedraza, CTranslational Psychiatry. 2017

Microglia Morphological Categorization in a Rat Model of Neuroinflammation by Hierarchical Cluster and Principal Components Analysis

Fernandez-Arjona, MD; Grondona, JM; Granados-Duran, P; Fernandez-Llebrez, P; Lopez-Avalos, MDFrontiers In Cellular Neuroscience. 2017

Perianal Pediatric Crohn Disease Is Associated With a Distinct Phenotype and Greater Inflammatory Burden

Assa, A; Amitai, M; Greer, ML; Castro, DA; Kuint, RC; Martinez-Leon, M; Herman-Sucharska, I; Coppenrath, E; Anupindi, S; Towbin, A; Moote, D; Konen, O; Pratt, LT; Griffiths, A; Turner, DJournal Of Pediatric Gastroenterology And Nutrition. 2017

Ventricular Zone Disruption in Human Neonates With Intraventricular Hemorrhage

McAllister, JP; Guerra, MM; Ruiz, LC; Jimenez, AJ; Dominguez-Pinos, D; Sival, D; den Dunnen, W; Morales, DM; Schmidt, RE; Rodriguez, EM; Limbrick, DDJournal Of Neuropathology And Experimental Neurology. 2017

Microbial neuraminidase induces a Moderate and Transient Myelin Vacuolation independent of complement system activation

Granados-Duran, P; Lopez-Avalos, MD; Cifuentes, M; Perez-Martin, M; Fernandez-Arjona, MD; Hughes, TR; Johnson, K; Morgan, BP; Fernandez-Llebrez, P; Grondona, JMFrontiers In Neurology. 2017

A vesicle trafficking protein alpha SNAP regulates Paneth cell differentiation in vivo

Lechuga, S; Naydenov, NG; Feygin, A; Jimenez, AJ; Ivanov, AIBiochemical And Biophysical Research Communications. 2017


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