{"id":39050,"date":"2024-07-12T10:57:33","date_gmt":"2024-07-12T10:57:33","guid":{"rendered":"https:\/\/ibima.eu\/?p=39050"},"modified":"2024-07-24T19:55:31","modified_gmt":"2024-07-24T19:55:31","slug":"assert","status":"publish","type":"post","link":"https:\/\/ibima.eu\/en\/assert\/","title":{"rendered":"ASSERT"},"content":{"rendered":"

[et_pb_section fb_built=\u00bb1″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_row _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_heading title=\u00bbDevelopment of a nanotechnology-based innovative assay for the diagnosis of allergy to Betalactams\u00bb _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb title_level=\u00bbh2″ title_font=\u00bb||||||||\u00bb title_text_align=\u00bbcenter\u00bb title_text_color=\u00bb#0C71C3″ custom_margin=\u00bb30px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb2_3,1_3″ _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb custom_padding=\u00bb30px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb2_3″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb hover_enabled=\u00bb0″ global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb sticky_enabled=\u00bb0″]<\/p>\n

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Financed by<\/strong>: European Union<\/span><\/p>\n

Programme<\/strong>: H2020- Call:\u00a0MARIE SKLODOWSKA-CURIE: INDIVIDUAL FELLOWSHIPS- EUROPEAN FELLOWSHIPS 2020\u00a0 \u00a0\u00a0<\/span><\/p>\n

Grant agreement ID:<\/span>\u00a0<\/span><\/b>101027955<\/a><\/p>\n

Start date:\u00a0<\/strong>10\/09\/2021<\/span><\/p>\n

End date:\u00a0<\/strong>09\/09\/2024<\/span><\/p>\n

<\/span><\/p>\n

Beneficiary<\/strong>:\u00a0Cecilia Frecha<\/span><\/p>\n

Supervisor:<\/strong>\u00a0Mar\u00eda Jos\u00e9 Torres Ja\u00e9n<\/span><\/p>\n

Implementation centre:<\/strong><\/span>\u00a0Hospital Regional Universitario de M\u00e1laga<\/a><\/span><\/p>\n

Research group of IBIMA involved:<\/span>\u00a0<\/span><\/strong>Drug and Allergen Allergic Diseases<\/a><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n

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[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_post_title title=\u00bboff\u00bb meta=\u00bboff\u00bb admin_label=\u00bbT\u00edtulo de publicaci\u00f3n\u00bb _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb title_font=\u00bbArial||||||||\u00bb title_text_align=\u00bbcenter\u00bb title_text_color=\u00bb#2ea3f2″ title_font_size=\u00bb35px\u00bb background_color=\u00bb#000000″ background_enable_image=\u00bboff\u00bb text_orientation=\u00bbcenter\u00bb width=\u00bb100%\u00bb max_width=\u00bb100%\u00bb module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb25%||1%||false|false\u00bb title_font_size_last_edited=\u00bboff|desktop\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_post_title][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb min_height=\u00bb1024.6px\u00bb custom_padding=\u00bb50px||50px||true|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_heading title=\u00bbABSTRACT\u00bb _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#0C71C3″ global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][et_pb_text _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n

Betalactams (BL) are the most widely used antibiotics and the first-choice drugs to control several bacterial infections, however, they can lead to serious allergic reactions in up to 10% of the general population. The current diagnosis of allergy to BL includes skin test and\/or drug provocation tests, which are invasive and carry a risk of anaphylaxis requiring hospitalisation. Basophil activation test (BAT) is one of the best options for diagnosis of allergy because it is free of risk and at a reduced cost for health care. The ASSERT project will bring a nanotechnology-based BAT assay specific for allergy to BL with higher sensitivity and specificity, which are the main weakness of the current assays. Of importance, the number and conformation of displayed antigens at the nanoparticle surface will be controlled to assure standardisation and increase precision and reproducibility of the assay. In addition, a complete validation plan is envisaged to fit the standards for clinical diagnostics. The two factors for the success of the project are, one one hand, the solid experience of the host lab in immunology, specially allergy and nanoparticle technology and, on the other hand, the expertise of the candidate in<\/span>
immunology, molecular biology and test validation design for clinical diagnostics. Moreover, the the two way of transfer of knowledge is assured, which will help the candidate to restart her research career in the European Union. Finally, the expected results of the project will contribute to enlarge the basic knowledge about allergen-specific activation of basophils, and will give rise to an optimised BL-BAT assay with the required clinical and analytical validation to be used in diagnostics.<\/span><\/p>\n

[\/et_pb_text][et_pb_heading title=\u00bbCommunication Actions\u00bb _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#0C71C3″ custom_margin=\u00bb30px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][et_pb_heading title=\u00bbParticipation of Dr Cecilia Frecha in European Researchers\u2019 Night 2023″ _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb title_level=\u00bbh3″ title_font=\u00bb||||||||\u00bb title_text_align=\u00bbcenter\u00bb title_text_color=\u00bb#0C71C3″ module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb30px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][et_pb_text _builder_version=\u00bb4.25.1″ _module_preset=\u00bbdefault\u00bb custom_margin=\u00bb14px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n

\ud83d\udd2c On September 29th 2023, Dr. Cecilia Frecha, showcased their groundbreaking research at \u2018The European Researchers\u2019 Night\u2019 in M\u00e1laga using gamification techniques to make biomedical science engaging for everyone. \ud83c\udfae<\/span><\/p>\n

Check how it was clicking on any of our social media profiles<\/span><\/p>\n

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Click on the picture for the full interview<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n

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Financed by: European Union Programme: H2020- Call:\u00a0MARIE SKLODOWSKA-CURIE: INDIVIDUAL FELLOWSHIPS- EUROPEAN FELLOWSHIPS 2020\u00a0 \u00a0\u00a0 Grant agreement ID:\u00a0101027955 Start date:\u00a010\/09\/2021 End date:\u00a009\/09\/2024 Beneficiary:\u00a0Cecilia Frecha Supervisor:\u00a0Mar\u00eda Jos\u00e9 Torres Ja\u00e9n Implementation centre:\u00a0Hospital Regional Universitario de M\u00e1laga Research group of IBIMA involved:\u00a0Drug and Allergen Allergic Diseases    Betalactams (BL) are the most widely used antibiotics and the first-choice drugs […]<\/p>\n","protected":false},"author":2,"featured_media":39051,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[2191],"tags":[],"class_list":["post-39050","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-proyectos-de-investigacion"],"acf":[],"yoast_head":"\nASSERT - 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