[et_pb_section fb_built=\u00bb1″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_row _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_heading title=\u00bbProspective European Drug-Induced Liver Injury Network\u00bb _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_align=\u00bbcenter\u00bb title_text_color=\u00bb#0C71C3″ module_alignment=\u00bbcenter\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb3_5,2_5″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb custom_padding=\u00bb30px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb3_5″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n
Financed by<\/strong>: European Comission<\/span><\/p>\n Programme<\/strong>: EUROPEAN COOPERATION IN SCIENCE AND TECHNOLOGY (COST) 2017<\/span><\/p>\n Reference: <\/b><\/span>CA17112<\/u><\/span><\/a><\/p>\n Rol: <\/strong>Coordinator<\/span><\/p>\n Duration:\u00a0<\/b>October 2018 to April 2023<\/span><\/p>\n [\/et_pb_text][et_pb_heading title=\u00bbRepresentantives:\u00bb _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb title_level=\u00bbh2″ title_font=\u00bb||||||||\u00bb title_text_align=\u00bbleft\u00bb title_text_color=\u00bb#0C71C3″ module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb27px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][\/et_pb_column][et_pb_column type=\u00bb2_5″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_post_title title=\u00bboff\u00bb meta=\u00bboff\u00bb admin_label=\u00bbT\u00edtulo de publicaci\u00f3n\u00bb _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb title_font=\u00bbArial||||||||\u00bb title_text_align=\u00bbcenter\u00bb title_text_color=\u00bb#2ea3f2″ title_font_size=\u00bb35px\u00bb background_color=\u00bbRGBA(255,255,255,0)\u00bb text_orientation=\u00bbcenter\u00bb width=\u00bb100%\u00bb module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb9%||1%||false|false\u00bb hover_enabled=\u00bb0″ title_font_size_last_edited=\u00bboff|desktop\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb sticky_enabled=\u00bb0″][\/et_pb_post_title][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\u00bb1_2,1_2″ _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb custom_padding=\u00bb30px||||false|false\u00bb hover_enabled=\u00bb0″ global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb custom_margin=\u00bb-16px||||false|false\u00bb sticky_enabled=\u00bb0″][et_pb_column type=\u00bb1_2″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb hover_enabled=\u00bb0″ global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb sticky_enabled=\u00bb0″]<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_2″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb hover_enabled=\u00bb0″ global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb sticky_enabled=\u00bb0″]<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb custom_margin=\u00bb-2px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb4_4″ _builder_version=\u00bb4.25.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_heading title=\u00bbABSTRACT\u00bb _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb title_level=\u00bbh2″ title_font=\u00bb||||||||\u00bb title_text_align=\u00bbleft\u00bb title_text_color=\u00bb#0C71C3″ module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb-5px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][et_pb_text _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n There is a clear unmet need for a deeper understanding of idiosyncratic drug-induced liver injury (DILI), a multi-layered challenge that spans the life of the drug from pre-clinical development to clinical trials and post-marketing.<\/span><\/p>\n The objectives of the PRO-EURO-DILI-NET Cost Action are to create a unique, co-operative, interdisciplinary European-based DILI network of stakeholders to co-ordinate efforts in DILI, to facilitate bi-directional exchange of discovered knowledge and generated hypotheses among different disciplines, and to promote clinically impactful knowledge discovery and its translation into clinical practice.\u00a0<\/span><\/p>\n This Action will: (a) harmonize efforts for in-depth DILI phenotyping and bio-sample repository and coordinate pre-funded database\/repository studies to aggregate a large number of DILI cases in a standardized manner (WG1);<\/span><\/p>\n (b) Establish a strategy for development, validation and performance of DILI novel biomarkers and explore multifactorial DILI risk modifiers in clinical data sets using novel approaches for future precision medicine (WG2);<\/span><\/p>\n (c) Facilitate clinically impactful knowledge discovery by introducing biological variations and the complexity (i.e., multi-cellular\/multi-organ systems) into toxicological experiments to assess hepatotoxicity to guide future drug safety testing (WG3).<\/span><\/p>\n (d) Define criteria and establish endpoints to measure efficacy on novel interventions in DILI (WG4);<\/span><\/p>\n (e) Draft policy recommendations about near-patient testing tools.<\/span><\/p>\n \u00a0The network will promote and coordinate a highly translational and innovative research program in Europe and beyond with the ultimate goal to pre-empt and prevent DILI, develop innovative therapeutic approaches that could improve clinical outcomes and enhance public awareness, while developing a forum for knowledge exchange and training of young European researches.<\/span><\/p>\n <\/span><\/p>\n <\/span><\/p>\n [\/et_pb_text][et_pb_button button_url=\u00bbhttps:\/\/proeurodilinet.eu\/\u00bb button_text=\u00bbWebsite of the Network\u00bb button_alignment=\u00bbcenter\u00bb _builder_version=\u00bb4.27.0″ _module_preset=\u00bbdefault\u00bb custom_button=\u00bbon\u00bb button_text_color=\u00bb#FFFFFF\u00bb button_bg_color=\u00bb#0c71c3″ background_layout=\u00bbdark\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Financed by: European Comission Programme: EUROPEAN COOPERATION IN SCIENCE AND TECHNOLOGY (COST) 2017 Reference: CA17112 Rol: Coordinator Duration:\u00a0October 2018 to April 2023 RA\u00daL ANDRADE BELLIDO ,\u00a0Chair MAR\u00cdA ISABEL\u00a0LUCENA,\u00a0MC Member\u00a0\u00a0 NIU HAO,Participant in work package 3 DANIEL ENRIQUE DI ZEO S\u00c1NCHEZ,Participant in work package 4 AIDA ORTEGA ALONSO, Participant in work package 1,4,5 ENRIQUE DEL CAMPO […]<\/p>\n","protected":false},"author":2,"featured_media":44892,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[2192],"tags":[],"class_list":["post-44601","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-redes-cooperacion"],"acf":[],"yoast_head":"\n\n
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