{"id":47937,"date":"2024-07-31T11:37:35","date_gmt":"2024-07-31T11:37:35","guid":{"rendered":"https:\/\/ibima.eu\/?p=47937"},"modified":"2024-07-31T11:41:05","modified_gmt":"2024-07-31T11:41:05","slug":"high-performance-cloud-and-symbolic-computing-in-big-data-problems-applied-to-mathematical-modelling-of-comparative-genomics","status":"publish","type":"post","link":"https:\/\/ibima.eu\/en\/high-performance-cloud-and-symbolic-computing-in-big-data-problems-applied-to-mathematical-modelling-of-comparative-genomics\/","title":{"rendered":"High Performance, Cloud and Symbolic Computing in Big-Data problems applied to mathematical modelling of Comparative Genomics"},"content":{"rendered":"<p>[et_pb_section fb_built=\u00bb1&#8243; _builder_version=\u00bb4.25.0&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_row column_structure=\u00bb3_5,2_5&#8243; _builder_version=\u00bb4.25.0&#8243; _module_preset=\u00bbdefault\u00bb custom_padding=\u00bb30px||||false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb3_5&#8243; _builder_version=\u00bb4.25.0&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.27.0&#8243; _module_preset=\u00bbdefault\u00bb hover_enabled=\u00bb0&#8243; global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb sticky_enabled=\u00bb0&#8243;]<\/p>\n<p><span style=\"color: #000000;\"><strong>Financed by<\/strong>\u00a0: European Commission<\/span><\/p>\n<p><strong><span><span style=\"color: #000000;\">Grant Agreement ID:<\/span> <\/span><\/strong><a href=\"https:\/\/cordis.europa.eu\/project\/id\/324554\/reporting\"><span>324554<\/span><\/a><\/p>\n<p><span style=\"color: #000000;\"><strong>Program<\/strong>\u00a0: FP7-PEOPLE-2012-IAPP \u2013 Marie Curie Action: \u201cIndustry-Academia Partnerships and Pathways\u201d<\/span><\/p>\n<p><span style=\"color: #000000;\"><b><span class=\"\">Duration:<\/span><\/b><span class=\"\">\u00a0February 2013 to March 2017<\/span><\/span><\/p>\n<p><span style=\"color: #000000;\"><\/span><\/p>\n<p><span style=\"color: #000000;\">Beneficiario:Perkins, James<\/span><\/p>\n<p><span style=\"color: #000000;\">Supervisor:Blanca G\u00f3mez, Miguel<\/span><\/p>\n<p><span style=\"color: #000000;\">Implementation centre: Hospital Regional Universitario de M\u00e1laga<\/span><\/p>\n<p><span style=\"color: #000000;\">Research group of IBIMA involved: Molecular Basis of Cellular Proliferation and Rare Diseases<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb2_5&#8243; _builder_version=\u00bb4.25.0&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_post_title title=\u00bboff\u00bb meta=\u00bboff\u00bb admin_label=\u00bbT\u00edtulo de publicaci\u00f3n\u00bb _builder_version=\u00bb4.27.0&#8243; _module_preset=\u00bbdefault\u00bb title_font=\u00bbArial||||||||\u00bb title_text_align=\u00bbcenter\u00bb title_text_color=\u00bb#2ea3f2&#8243; title_font_size=\u00bb35px\u00bb background_color=\u00bbRGBA(255,255,255,0)\u00bb text_orientation=\u00bbcenter\u00bb width=\u00bb100%\u00bb module_alignment=\u00bbcenter\u00bb custom_margin=\u00bb1%||1%||false|false\u00bb hover_enabled=\u00bb0&#8243; title_font_size_last_edited=\u00bboff|desktop\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb sticky_enabled=\u00bb0&#8243;][\/et_pb_post_title][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00bb4.27.0&#8243; _module_preset=\u00bbdefault\u00bb min_height=\u00bb305.4px\u00bb custom_margin=\u00bb-16px||||false|false\u00bb custom_padding=\u00bb50px||50px||true|false\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.25.0&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_heading title=\u00bbABSTRACT\u00bb _builder_version=\u00bb4.25.1&#8243; _module_preset=\u00bbdefault\u00bb title_font=\u00bb||||||||\u00bb title_text_color=\u00bb#0C71C3&#8243; locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_heading][et_pb_text _builder_version=\u00bb4.27.0&#8243; _module_preset=\u00bbdefault\u00bb hover_enabled=\u00bb0&#8243; global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb sticky_enabled=\u00bb0&#8243;]<\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">Large scale genomics projects exploiting high throughput leading technology have produced and continue to produce massive data sets with exponential growing rates. So far, only a small part of this data can be abstracted, managed and processed, giving an incomplete understanding of the biological process being observed. The lack of processing power is a bottle neck in acquiring results. Comparative genomics is a good example since it includes all the ingredients: huge and ever growing datasets, complex applications that demands large computational resources and new mathematical and statistical models for analysing and synthetizing genomic information. A promising approach to address such massive data sets is the creation of new computer software that makes effective use of parallel processing.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"color: #000000;\">This proposal pursues the linking of different research domains to come up with a coordinated multi-disciplinary approach in the development of tools targeting Big-Data and computationally intensive scientific applications. Generic solutions for Big-Data storage, management, distribution, processing and final analysis will be developed. These solutions will target a broad range of scientific applications, in concrete, as proof-of-concept they will be implemented in the \u2018Comparative Genomics\u2019 field of bioinformatics and biomedical domains. Applications such as the detection of main evolutionary events, new comparative genomics\u2019 models that can be evaluated experimentally, for inter-species evolutionary distance, the composition of the k-mers dictionaries for each specie, or customising symbolic computing methods to determine the consensus tree from a sequence of trees with application in multiple sequence alignments, phylogenetic studies, clustering algorithms, etc. present in diverse fields of bioinformatics, from NGS-DNA assembly to gene-expression, all of them well suited applications to apply HPC-CC approaches and with high and attractive potential for commercialization.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Financed by\u00a0: European Commission Grant Agreement ID: 324554 Program\u00a0: FP7-PEOPLE-2012-IAPP \u2013 Marie Curie Action: \u201cIndustry-Academia Partnerships and Pathways\u201d Duration:\u00a0February 2013 to March 2017 Beneficiario:Perkins, James Supervisor:Blanca G\u00f3mez, Miguel Implementation centre: Hospital Regional Universitario de M\u00e1laga Research group of IBIMA involved: Molecular Basis of Cellular Proliferation and Rare DiseasesLarge scale genomics projects exploiting high throughput leading [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":47939,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[2193],"tags":[],"class_list":["post-47937","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-recursos-humanos"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - 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