
Arteriosclerosis, Prevención Vascular, Metabolismo y Enfermedades Neurológicas
References
- Masana L, Plana N, Pérez-Calahorra S, Ibarretxe D, Lamiquiz-Moneo I, Pedro-Botet J, Suárez-Tembra M, Valdivielso P, Ortega E, Civeira F; Dyslipidemia Registry of the Spanish Arteriosclerosis Society. How many familial hypercholesterolemia patients are eligible for PCSK9 inhibition? Atherosclerosis. 2017 Jul;262:107-112. PMID: 28531826.
- Rev Esp Cardiol (Engl Ed). 2017 Nov;70(11):941-951. PMID: 28291729.
- García-Casares N, Bernal-López MR, Roé-Vellvé N, Gutiérrez-Bedmar M, Fernández-García JC, García-Arnés JA, Ramos-Rodriguez JR, Alfaro F, Santamaria-Fernández S, Steward T, Jiménez-Murcia S, Garcia-Garcia I, Valdivielso P, Fernández-Aranda F, Tinahones FJ, Gómez-Huelgas R. Brain Functional Connectivity Is Modified by a Hypocaloric Mediterranean Diet and Physical Activity in Obese Women. Nutrients. 2017 Jul 1;9(7). PMID: 28671558.
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Lineas de Investigación
01. Alteraciones del metabolismo de las lipoproteinas
02. Enfermedades raras. PXE, Turner, Quilomicronemia familiar
03. Epidemiología, estratificación y prevención del riesgo cardiovascular
04. Uso del PET/TAC y RN-3T en la evaluación de la enfermedad arteriosclerótica
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Otro

Proyectos de Investigación
BICE 05-20 Caracterización clínica de sujetos con hiperalfalipoproteinemia extrema e identificación de variantes de secuencia en genes candidatos
Sociedad Española de ArteriosclerosisHomeostasis Mitocondrial en la Hipertrigliceridemia y Su Modulación Mediante MiRNA
Junta de AndalucíaPapel del heteromero GALR2/NPYY1R en la neurogénesis hipocampal: una posible estrategia terapeútica para la enfermedad de Alzheimer
Junta de AndalucíaPI19/01375 Biomarcadores de deterioro cognitivo mediante neuroimagen estructural (tractografía) y funcional (conectividad cerebal) en pacientes con diabetes tipo 2.
ISCIIIPapel del heteromero GALR2/NPYY1R en la neurogenesis hipocampal: Una posible estrategia terapeutica para la enfermedad de Alzheimer
Programa Operativo FEDER Andalucía 2014-2020Biomarcadores de deterioro cognitivo mediante neuroimagen estructural (tractografia) y funcional (conectividad cerebral) en pacientes con diabetes tipo 2.
INSTITUTO DE SALUD CARLOS IIIPI16/01579 PET/TAC con 18NAF en la cuantificación del depósito de calcio cutáneo y vascular y su relación con el estadío clínico en pacientes con Pseudoxanthoma Elasticum
INSTITUTO DE SALUD CARLOS IIIPI18-01809 PROYECTO IBERSCORE-2: ELABORACION DE FUNCIONES PREDICTIVAS DE RIESGO CARDIOVASCULAR TRAS UN SEGUIMIENTO DE 10 AÑOS DE LA COHORTE ICARIA.
INSTITUTO DE SALUD CARLOS IIIPIN-0180-2018 APLICACIÓN DE MÉTODOS DE SECUENCIACIÓN DE NUEVA GENERACIÓN O NGS PARA EL DIAGNÓSTICO MOLECULAR DEL SÍNDROME DE QUILOMICRONEMIA FAMILIAR.
CONSEJERÍA DE SALUDEstudios Clínicos
LPS14245. Estudio Multinacional, Multicéntrico, de un Solo Grupo y Abierto para Documentar la Seguridad, la Tolerabilidad y el Efecto de Alirocumab sobre las lipoproteínas aterogénicas en Pacientes de Alto Riesgo Cardiovascular con Hipercolesterolemia Severa no con
SANOFI-AVENTIS, S.A.FMD-TRI-2016-01. Estudio de fase III, internacional, multicéntrico, aleatorizado y abierto, para evaluar la eficacia en la reducción de cLDL y presión arterial, y la seguridad de Trinomia® versus tratamiento habitual en pacientes de muy alto riesgo cardiovascular sin even
FERRER INTERNATIONAL S.AFIM-PXE-2016-01. Respuesta al lansoprazol oral de los niveles del pirofosfato inorgánico en pacientes con enfermedad de Grönblad-Stranberg (Pseudoxantoma Elasticum)
FUNDACION PÚBLICA ANDALUZA PARA LA INVESTIGACION DE MALAGA EN BIOMEDICINA Y SALUD FIMABISEFC11570. Ensayo aleatorizado, doble ciego, controlado con placebo y con grupos paralelos para evaluar el efecto de SAR236553/REGN727 sobre la aparición de acontecimientos cardiovasculares en pacientes que han experimentado recientemente un síndrome coronario agudo
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENTPublicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
Clinical and genetic differences between heterozygous familial hypercholesterolemia patients with and without type 2 diabetes
Climent E, Pérez-Calahorra S, Benaiges D, Pintó X, Suárez-Tembra M, Plana N, Sánchez-Hernández RM, Valdivielso P, Ascaso JF, Pedro-Botet J
Rev Esp Cardiol (Engl Ed) 2020 Sep;73(9):718-724
Development of [18F]ICMT-11 for Imaging Caspase-3/7 Activity during Therapy-Induced Apoptosis
García-Argüello SF, Lopez-Lorenzo B, Cornelissen B, Smith G
Cancers (Basel) 2020 Aug 6;12(8):2191
Evaluation of the chylomicron-TG to VLDL-TG ratio for type I hyperlipoproteinemia diagnostic
Rioja J, Ariza MJ, García-Casares N, Coca-Prieto I, Arrobas T, Muñiz-Grijalvo O, Mangas A, Ibarretxe D, Sánchez-Chaparro MÁ, Valdivielso P
Eur J Clin Invest 2020 Dec;50(12):e13345
Postprandial Apolipoprotein B48 is Associated with Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis
Mena-Vázquez N, Rojas-Gimenez M, Jimenez Nuñez FG, Manrique-Arija S, Rioja J, Ruiz-Limón P, Ureña I, Castro-Cabezas M, Valdivielso P, Fernández-Nebro A
J Clin Med 2020 Aug 2;9(8):2483
Relationship Between Mitochondrial Structure and Bioenergetics in Pseudoxanthoma elasticum Dermal Fibroblasts
Lofaro FD, Boraldi F, Garcia-Fernandez M, Estrella L, Valdivielso P, Quaglino D
Front Cell Dev Biol 2020 Dec 17;8:610266
Skin and Arterial Wall Deposits of 18F-NaF and Severity of Disease in Patients with Pseudoxanthoma Elasticum
Gutierrez-Cardo A, Lillo E, Murcia-Casas B, Carrillo-Linares JL, García-Argüello F, Sánchez-Sánchez P, Rodriguez-Morata A, Aranda IB, Sánchez-Chaparro MÁ, García-Fernández M, Valdivielso P
J Clin Med 2020 May 8;9(5):1393
Subclinical Arteriosclerosis is Associated With Common Vascular Risk Factors in Long-Term Survivors of Testicular Cancer
Espíldora-Hernández J, Díaz-Antonio T, Baena-Espinar J, Alonso-Calderón I, Rioja J, Alba-Conejo E, Valdivielso P, Sánchez-Chaparro MÁ
J Clin Med 2020 Mar 31;9(4):971
White matter lesions and temporal atrophy are associated with cognitive and neuropsychiatric symptoms in patients with hypertension and Alzheimer’s disease
García-Alberca JM, Mendoza S, Gris E, Royo JL, Cruz-Gamero JM, García-Casares N
Int J Geriatr Psychiatry 2020 Nov;35(11):1292-1300
COVID-19 and Sick Leave: An Analysis of the Ibermutua Cohort of Over 1,651,305 Spanish Workers in the First Trimester of 2020
Calvo-Bonacho E, Catalina-Romero C, Fernández-Labandera C, Fernández-Meseguer A, González-Quintela A, Martínez-Muñoz P, Quevedo L, Valdivielso P, Sánchez-Chaparro MÁ
Front Public Health 2020 Oct 19;8:580546
Genetic variants in the LPL and GPIHBP1 genes, in patients with severe hypertriglyceridaemia, detected with high resolution melting analysis
Ariza MJ, Pérez-López C, Almagro F, Sánchez-Tévar AM, Muñiz-Grijalvo O, Álvarez-Sala Walter LA, Rioja J, Sánchez-Chaparro MÁ, Valdivielso P
Clin Chim Acta 2020 Jan;500:163-171
Neuroplasticity and Epilepsy Surgery in Brain Eloquent Areas: Case Report
Serrano-Castro PJ, Ros-López B, Fernández-Sánchez VE, García-Casares N, Muñoz-Becerra L, Cabezudo-Garcia P, Aguilar-Castillo MJ, Vidal-Denis M, Cruz-Andreotti E, Postigo-Pozo MJ, Estivill-Torrús G, Ibañez-Botella G
Front Neurol 2020 Jul 29;11:698
Overall Mortality and LDL Cholesterol Reduction in Secondary Prevention Trials of Cardiovascular Disease
Pedro-Botet J, López-Miranda J, Badimón L, Civeira F, Guijarro C, Millán J, Mostaza JM, Pintó X, Valdivielso P, Masana L; Expert group from the Spanish Arteriosclerosis Society
Am J Cardiovasc Drugs 2020 Aug;20(4):325-332
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- Santotoribio, JD, Cuadros-Muñoz, JF, García-Casares, N. Comparison of C Reactive Protein and Procalcitonin Levels in Cerebrospinal Fluid and Serum to Differentiate Bacterial from Viral Meningitis. Ann Clin Lab Sci. 2018;48 (4):506-510. . PubMed PMID:30143494 .
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- González-Amores, Y, Clavijo-Frutos, E, Salas-Casanova, C, Alcain-Martínez, G. Direct parasitologial diagnosis of infection with Hysterothylacium aduncum in a patient with epigastralgia. Rev Esp Enferm Dig. 2015;107 (11):699-700. . PubMed PMID:26561913 .
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- Catalina-Romero, C, Ruilope, LM, Sánchez-Chaparro, MA, Valdivielso, P, Cabrera-Sierra, M, Fernández-Labandera, C et al.. Factors influencing return-to-work after cerebrovascular disease: the importance of previous cardiovascular risk. Eur J Prev Cardiol. 2015;22 (9):1220-7. doi: 10.1177/2047487314544961. PubMed PMID:25059932 .
- Jiménez Villodres, M, García Gutiérrez, G, García Frías, P, Rioja Villodres, J, Martín Velázquez, M, Sánchez Chaparro, MÁ et al.. Fractional excretion of phosphorus and vascular calcification in stage 3 chronic kidney disease. J Investig Med. 2019;67 (3):674-680. doi: 10.1136/jim-2018-000852. PubMed PMID:30429202 .
- Garzón-Maldonado, FJ, Gutiérrez-Bedmar, M, García-Casares, N, Pérez-Errázquin, F, Gallardo-Tur, A, Martínez-Valle Torres, MD et al.. Health-related quality of life in caregivers of patients with Alzheimer's disease. Neurologia. 2017;32 (8):508-515. doi: 10.1016/j.nrl.2016.02.023. PubMed PMID:27126568 .
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Comparison of C Reactive Protein and Procalcitonin Levels in Cerebrospinal Fluid and Serum to Differentiate Bacterial from Viral Meningitis
Santotoribio, JD; Cuadros-Munoz, JF; Garcia-Casares, N
Annals Of Clinical And Laboratory Science 2018
Document of recommendations of the SEA 2018. Lifestyle in cardiovascular prevention
Perez-Jimenez, F; Pascual, V; Meco, JF; Martinez, PP; Lista, JD; Domenech, M; Estruch, R; Leon-Acuna, A; Lopez-Miranda, J; Sanchez-Ramos, A; Ferrer, CSI; Soler-Rivas, C; Alberich, RMS; Valdivielso, P; Ros, E
Clinica E Investigacion En Arteriosclerosis 2018
COSMIC project: consensus on the objectives of the metabolic syndrome in clinic
Pedro-Botet, J; Ascaso, JF; Barrios, V; De la Sierra, A; Escalada, J; Millan, J; Mostaza, JM; Perez-Martinez, P; Pinto, X; Salas-Salvado, J; Valdivielso, P
Diabetes Metabolic Syndrome And Obesity-Targets And Therapy 2018
Evidence for increased chylomicron remnants in rheumatoid arthritis
Burggraaf, B; van Breukelen-van der Stoep, DF; van Zeben, J; van der Meulen, N; van de Geijn, GJM; Liem, A; Valdivielso, P; Villodres, JR; Ramirez-Bollero, J; van der Zwan, E; Cabezas, MC
European Journal Of Clinical Investigation 2018
The Effects of Parenteral K1 Administration in Pseudoxanthoma Elasticum Patients Versus Controls. A Pilot Study
Carrillo-Linares, JL; Garcia-Fernandez, M; Morillo, MJ; Sanchez, P; Rioja, J; Baron, FJ; Ariza, MJ; Harrington, DJ; Card, D; Boraldi, F; Quaglino, D; Valdivielso, P
Frontiers In Medicine 2018
Molecular basis of the familial chylomicronemia syndrome in patients from the National Dyslipidemia Registry of the Spanish Atherosclerosis Society.
Ariza, Maria Jose; Rioja, Jose; Ibarretxe, Daiana; Camacho, Ana; Diaz-Diaz, Jose Luis; Mangas, Alipio; Carbayo-Herencia, Julio A; Ruiz-Ocana, Pablo; Lamiquiz-Moneo, Itziar; Mosquera, Daniel; Saenz, Pedro; Masana, Luis; Muniz-Grijalvo, Ovidio; Perez-Calahorra, Sofia; Valdivielso, Pedro
Journal Of Clinical Lipidology 2018
Music Therapy in Parkinson’s Disease
Garcia-Casares, N; Martin-Colom, JE; Garcia-Arnes, JA
Journal Of The American Medical Directors Association 2018
High risk of subclinical atherosclerosis in COPD exacerbator phenotype
Domenech, A; Munoz-Montiel, A; Garcia-Casares, N; Rioja, J; Ruiz-Esteban, P; Gutierrez-Castano, P; Pardell, MJP; Olveira, C; Valdivielso, P; Sanchez-Chaparro, MA
Respiratory Medicine 2018
Outbreak of acute hepatitis A in the health area served by the Hospital Universitario Virgen de la Victoria (HUVV): a change in epidemiology
Garcia-Ferreira, AJ; Ortega-Alonso, A; Cobos-Rodriguez, J; Bardon-de-Tena, P; Calderon-Cid, M; Garcia-Garcia, A; Garcia-Escano, MD; Alcantara-Benitez, R; Clavijo-Frutos, E; Garcia-Cortes, M; Andrade, RJ
Revista Espanola De Enfermedades Digestivas 2018
How many familial hypercholesterolemia patients are eligible for PCSK9 inhibition?
Masana, L; Plana, N; Perez-Calahorra, S; Ibarretxe, D; Lamiquiz-Moneo, I; Pedro-Botet, J; Suarez-Tembra, M; Valdivielso, P; Ortega, E; Civeira, FAtherosclerosis. 2017
Association Between Improvement in Cardiovascular Risk Profile and Changes in Sickness Absence: Results of the ICARIA Study
Calvo-Bonacho, E (Calvo-Bonacho, Eva)[ 1 ] ; Catalina-Romero, C (Catalina-Romero, Carlos)[ 1 ] ; Cabrera, M (Cabrera, Martha)[ 1 ] ; Fernandez-Labandera, C (Fernandez-Labandera, Carlos)[ 1,3 ] ; Chaparro, MAS (Sanchez Chaparro, Miguel Angel)[ 2 ] ; Brotons, C (Brotons, Carlos); Ruilope, LM (Miguel Ruilope, Luis)[ 4 ]Revista Espanola De Cardiologia. 2017
Brain Functional Connectivity Is Modified by a Hypocaloric Mediterranean Diet and Physical Activity in Obese Women
Garcia-Casares, N; Bernal-Lopez, MR; Roe-Vellve, N; Gutierrez-Bedmar, M; Fernandez-Garcia, JC; Garcia-Arnes, JA; Ramos-Rodriguez, JR; Alfaro, F; Santamaria-Fernandez, S; Steward, T; Jimenez-Murcia, S; Garcia-Garcia, I; Valdivielso, P; Fernandez-Aranda, F; Tinahones, FJ; Gomez-Huelgas, R/Dirección para petición de copias: Tinahones, FJ (autor para petición de copias)Nutrients. 2017
Pulmonary Mucormycosis at Onset of Diabetes in a Young Patient
Espildora-Hernandez, J; Perez-Lopez, C; Abarca-Costalago, M; Nuno-Alvarez, EArchivos De Bronconeumologia. 2017
An assessesment of telephone assistance systems for caregivers of patients with Alzheimer”s disease
Garzon-Maldonado, FJ; Gutierrez-Bedmar, M; Serrano-Castro, V; Requena-Toro, MV; Padilla-Romero, L; Garcia-Casares, NNeurologia. 2017
Changes in fatty liver index after consuming a Mediterranean diet: 6-year follow-up of the PREDIMED-Malaga trial
Cueto-Galan, R; Baron, FJ; Valdivielso, P; Pinto, X; Corbella, E; Gomez-Gracia, E; Warnberg, JMedicina Clinica. 2017
Health-related quality of life in caregivers of patients with Alzheimer”s disease.
Garzon-Maldonado, F J; Gutierrez-Bedmar, M; Garcia-Casares, N; Perez-Errazquin, F; Gallardo-Tur, A; Martinez-Valle Torres, M DNeurologia. 2017
Music therapy as a non-pharmacological treatment in Alzheimer”s disease. A systematic review
Garcia-Casares, N; Moreno-Leiva, RM; Garcia-Arnes, JARevista De Neurologia. 2017
Familial mediterranean fever treated with anakinar: A case report
Espildora-Hernandez, J; Abarca-Costalago, MReumatologia Clinica. 2017
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