Lineas de Investigación

01. Estudio de los mecanismos implicados en la generación del cáncer de piel con búsqueda específica de nuevos factores pronósticos, así como el abordaje terapeútico de las mismas.

02. Prevención del cáncer cutáneo con investigaciones en el campo de la fotoprotección

03. Análisis de la etiopatogenia de la psoriasis y su tratamiento tanto por mecanismos inmunoterapeúticos y fototerapia.



Estudios Clínicos

Estudio prospectivo, multicéntrico y a largo plazo para evaluar la seguridad y la eficacia de Nemolizumab (CD14152) en sujetos con dermatitis atópica de moderada a grave.

GALDEMA, S.A
Fase: III Ensayo Clínico Comercial

Ensayo Clínico fase II para evaluar la seguridad y eficacia de dos modelos de piel autóloga creada mediante ingeniería de tejidos en la cirugía reconstructiva del carcinoma basocelular..

Fundación Pública Andaluza Progreso y Salud
Fase: II Ensayo Clínico Comercial

Estudio aleatorizado, doble ciego y controlado con placebo para evaluar la eficacia y la seguridad de nemolizumab (CD14152) en sujetos con dermatitis atópica de moderada a grave..

GALDERMA RESEARCH & DEVELOPMENT S.N.C.
Fase: III Ensayo Clínico Comercial

Estudio de extensión abierto y multicéntrico para caracterizar la seguridad y la eficacia a largo plazo de BMS-986165 en pacientes con psoriasis en placas de moderada a grave.

BRISTOL-MYERS SQUIBB COMPANY
Fase: III Ensayo Clínico Comercial

I1F-MC-RHBA.

Estudio multicéntrico, aleatorizado, en doble ciego y controlado con placebo, para comparar la eficacia y la seguridad de LY2439821 frente a etanercept y placebo en pacientes con psoriasis en placas de grado moderado a severo

ELI LILLY AND COMPANY
Fase: III ENSAYO CLINICO COMERCIAL

WA29330.

Estudio multicéntrico, aleatorizado, doble ciego, con doble simulación y comparador activo para evaluar la eficacia y la seguridad de rituximab en comparación con MMF en pacientes con pénfigo vulgar

F. HOFFMANN LA ROCHE LTD
Fase: III ENSAYO CLINICO COMERCIAL

CAIN457A3401.

Ensayo abierto, prospectivo, no aleatorizado, multicéntrico para evaluar el efecto de piel blanqueada en los resultados de calidad de vida relacionada con la salud a las 16 y 52 semanas en pacientes con psoriasis en placas de moderada a grave tratados con

NOVARTIS FARMACEUTICA, S.A.
Fase: IV ENSAYO CLINICO COMERCIAL

SP14019-18.

Evaluación de la solución de uso cutáneo SP14019-F-01 para el tratamiento de la dermatitis atópica. Estudio piloto. Estudio Cyclatop

SPHERIUM BIOMED S.L (ANTES JANUS DEVELOPMENT)
Fase: II ENSAYO CLINICO COMERCIAL

CAIN457A2323.

Estudio multicéntrico, aleatorizado, doble ciego, controlado con placebo, de 52 semanas de duración para demostrar la eficacia, seguridad y tolerabilidad de inyecciones subcutáneas de secukinumab con jeringas precargadas de 2 ml (300 mg) en pacientes adul

NOVARTIS FARMACEUTICA, S.A.
Fase: III ENSAYO CLINICO COMERCIAL

M-41008-41.

Estudio clínico abierto para evaluar la eficacia y la seguridad a largo plazo de dimetilfumarato en adultos con psoriasis crónica en placas moderada-grave en la práctica clínica (Estudio DIMESKIN 1)

ALMIRALL S.A.
Fase: IV ENSAYO CLINICO COMERCIAL


Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro


Long-term safety of nine systemic medications for psoriasis: A cohort study using the Spanish Registry of Adverse Events for Biological Therapy in Dermatological Diseases (BIOBADADERM) Registry

Daudén E, Carretero G, Rivera R, Ferrándiz C, Llamas-Velasco M, de la Cueva P, Belinchón I, Gómez-García FJ, Herrera-Acosta E, Ruiz-Genao DP, Ferrán-Farrés M, Alsina M, Baniandrés-Rodríguez O, Sánchez-Carazo JL, Sahuquillo-Torralba A, Fernández-Freire LR, Vilar-Alejo J, García-Donoso C, Carrascosa JM, Herrera-Ceballos E, López-Estebaranz JL, Botella-Estrada R, Segovia-Muñoz E, Descalzo MA, García-Doval I; BIOBADADERM Study Group
J Am Acad Dermatol 2020 Jul;83(1):139-150


Quality of Life of Cohabitants of People Living with Acne

Martínez-García E, Arias-Santiago S, Herrera-Acosta E, Affleck A, Herrera-Ceballos E, Buendía-Eisman A
Acta Derm Venereol 2020 Oct 14;100(17):adv00290


Skin and Arterial Wall Deposits of 18F-NaF and Severity of Disease in Patients with Pseudoxanthoma Elasticum

Gutierrez-Cardo A, Lillo E, Murcia-Casas B, Carrillo-Linares JL, García-Argüello F, Sánchez-Sánchez P, Rodriguez-Morata A, Aranda IB, Sánchez-Chaparro MÁ, García-Fernández M, Valdivielso P
J Clin Med 2020 May 8;9(5):1393


Comparative study of the efficacy and safety of secukinumab vs ixekizumab in moderate-to-severe psoriasis after 1 year of treatment: Real-world practice

Herrera-Acosta E, Garriga-Martina GG, Suárez-Pérez JA, Martínez-García EA, Herrera-Ceballos E
Dermatol Ther 2020 May;33(3):e13313


Effect of Nail Thickness on Visible Radiation Transmittance: Implications for New Photodynamic Therapy Technologies in Onychomycosis

de Gálvez EN, Aguilera J, de Gálvez MV, Fonda-Pascual P, Herrera-Ceballos E, Gago-Calderón A
Photochem Photobiol 2020 Nov;96(6):1267-1272


Ixekizumab vs ustekinumab for skin clearance in patients with moderate to severe psoriasis after a year of treatment: Real-world practice

Herrera-Acosta E, Garriga-Martina GG, Suárez-Pérez JA, Martínez-García E, Herrera-Ceballos E
Dermatol Ther 2020 Nov;33(6):e14202


Real-world effectiveness and safety of apremilast in psoriasis at 52 weeks: a retrospective, observational, multicentre study by the Spanish Psoriasis Group

Del Alcázar E, Suárez-Pérez JA, Armesto S, Rivera R, Herrera-Acosta E, Herranz P, Martín I, Montesinos E, Hospital M, Vilarrasa E, Ferran M, Ruiz-Villaverde R, Sahuquillo-Torralba A, Ruiz-Genao DP, Pérez-Barrio S, Muñoz C, Llamas M, Valentí F, Mitxelena MJ, López-Ferrer A, Carretero G, Vidal D, Mollet J, Belinchón I, Carrascosa JM
J Eur Acad Dermatol Venereol 2020 Dec;34(12):2821-2829

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  1. Valencia-Vera, E, Aguilera, J, Cobos, A, Bernabó, JL, Pérez-Valero, V, Herrera-Ceballos, E et al.. Association between seasonal serum folate levels and ultraviolet radiation. J Photochem Photobiol B. 2019;190 :66-71. doi: 10.1016/j.jphotobiol.2018.10.012. PubMed PMID:30502586 .
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  1. López Jiménez, P, Suárez Pérez, J, Herrera Acosta, E, Aguilera Arjona, J, Mendiola Fernández, MV, Bosch García, R et al.. Secukinumab versus ustekinumab for skin clearance in patients with moderate to severe psoriasis after a year of treatment: Real-world practice. Dermatol Ther. 2019;32 (4):e12937. doi: 10.1111/dth.12937. PubMed PMID:30983098 .
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  1. de la Coba, F, Aguilera, J, Korbee, N, de Gálvez, MV, Herrera-Ceballos, E, Álvarez-Gómez, F et al.. UVA and UVB Photoprotective Capabilities of Topical Formulations Containing Mycosporine-like Amino Acids (MAAs) through Different Biological Effective Protection Factors (BEPFs). Mar Drugs. 2019;17 (1):. doi: 10.3390/md17010055. PubMed PMID:30646557 PubMed Central PMC6356945.
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  1. de Gálvez, MV, Aguilera, J, Sánchez-Roldán, C, Herrera-Acosta, E, Herrera-Ceballos, E. Water-Filtered Infrared Radiation Decreases the Generation of Photodermatoses Dependent on Ultraviolet and Visible Radiation. Photochem Photobiol. 2019;95 (3):874-878. doi: 10.1111/php.13049. PubMed PMID:30447157 .
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  1. Baños-Arévalo, AJ, López-Navarro, N, Gallego-Domínguez, E, Herrera, E. Acral Metastasis of the Fingers: Report of 2 Cases. Actas Dermosifiliogr (Engl Ed). 2018;109 (10):e1-e4. doi: 10.1016/j.ad.2017.03.024. PubMed PMID:29724431 .
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  1. Garcia-Doval, I, Descalzo, MA, Mason, KJ, Cohen, AD, Ormerod, AD, Gómez-García, FJ et al.. Cumulative exposure to biological therapy and risk of cancer in patients with psoriasis: a meta-analysis of Psonet studies from Israel, Italy, Spain, the U.K. and Republic of Ireland. Br J Dermatol. 2018;179 (4):863-871. doi: 10.1111/bjd.16715. PubMed PMID:29723914 .
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  5. Zhu, L, Wei, Q, Porchas, M, Brierley, P, Friedman, M, Crosby, K et al.. Plant-based antimicrobials inactivate Listeria monocytogenes and Salmonella enterica on melons grown in different regions of the United States. Food Microbiol. 2022;101 :103876. doi: 10.1016/j.fm.2021.103876. PubMed PMID:34579844 .
  6. Lytou, AE, Schoina, E, Liu, Y, Michalek, K, Stanley, MS, Panagou, EZ et al.. Quality and Safety Assessment of Edible Seaweeds Alaria esculenta and Saccharina latissima Cultivated in Scotland. Foods. 2021;10 (9):. doi: 10.3390/foods10092210. PubMed PMID:34574321 PubMed Central PMC8472205.
  7. Zhang, W, Zhao, X, Diao, L, Li, H, Tong, Z, Gu, Z et al.. Highly Sensitive Uric Acid Detection Based on a Graphene Chemoresistor and Magnetic Beads. Biosensors (Basel). 2021;11 (9):. doi: 10.3390/bios11090304. PubMed PMID:34562894 PubMed Central PMC8468455.
  8. Li, J, Yang, Z, Mao, LF, Chen, RH, Yu, XF, Yang, XH et al.. Reverse transcription recombinase-aided amplification assay for rapid detection of the influenza A(H1N1)pdm09 H275Y mutation that confers oseltamivir resistance. Mol Cell Probes. 2021;60 :101771. doi: 10.1016/j.mcp.2021.101771. PubMed PMID:34560257 .
  9. Sankoh, A, Jin, W, Zhong, Z, He, J, Hong, Y, Giddings, R et al.. DFT-Spread Spectrally Overlapped Hybrid OFDM-Digital Filter Multiple Access IMDD PONs. Sensors (Basel). 2021;21 (17):. doi: 10.3390/s21175903. PubMed PMID:34502798 PubMed Central PMC8433889.
  10. Park, YJ, Woo, HY, Kim, MB, Ahn, J, Heo, J. Primary hepatic sarcoidosis presenting with cholestatic liver disease and mimicking primary biliary cholangitis. Yeungnam Univ J Med. 2021; :. doi: 10.12701/yujm.2021.01151. PubMed PMID:34411476 .
  11. Orellana Mendoza, E, Cuadrado, W, Yallico, L, Zárate, R, Quispe-Melgar, HR, Limaymanta, CH et al.. Heavy metals in soils and edible tissues of Lepidium meyenii (maca) and health risk assessment in areas influenced by mining activity in the Central region of Peru. Toxicol Rep. 2021;8 :1461-1470. doi: 10.1016/j.toxrep.2021.07.016. PubMed PMID:34401355 PubMed Central PMC8353470.
  12. Ma, X, Wu, J, Jiang, L, Wang, M, Deng, G, Qu, S et al.. On-chip integration of a metal-organic framework nanomaterial on a SiO2 waveguide for sensitive VOC sensing. Lab Chip. 2021;21 (17):3298-3306. doi: 10.1039/d1lc00503k. PubMed PMID:34378614 .
  13. Yang, M, Chen, Y, Yan, P, Dong, J, Duan, W, Xu, L et al.. A photoelectrochemical aptasensor of ciprofloxacin based on Bi24O31Cl10/BiOCl heterojunction. Mikrochim Acta. 2021;188 (9):289. doi: 10.1007/s00604-021-04952-5. PubMed PMID:34355248 .
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  1. de Troya-Martín, M, de Gálvez-Aranda, MV, Rivas-Ruiz, F, Blázquez-Sánchez, N, Fernández-Morano, MT, Padilla-España, L et al.. Prevalence and predictors of sunburn among beachgoers. Photodermatol Photoimmunol Photomed. 2018;34 (2):122-129. doi: 10.1111/phpp.12354. PubMed PMID:28976044 .
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  1. Belinchón, I, Ramos, JM, Carretero, G, Ferrándiz, C, Rivera, R, Daudén, E et al.. Adverse events associated with discontinuation of the biologics/classic systemic treatments for moderate-to-severe plaque psoriasis: data from the Spanish Biologics Registry, Biobadaderm. J Eur Acad Dermatol Venereol. 2017;31 (10):1700-1708. doi: 10.1111/jdv.14314. PubMed PMID:28485816 .
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  1. Pérez-Plaza, A, Carretero, G, Ferrandiz, C, Vanaclocha, F, Gómez-García, FJ, Herrera-Ceballos, E et al.. Comparison of phenotype, comorbidities, therapy and adverse events between psoriatic patients with and without psoriatic arthritis. Biobadaderm registry. J Eur Acad Dermatol Venereol. 2017;31 (6):1021-1028. doi: 10.1111/jdv.14188. PubMed PMID:28252811 .
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  1. Dávila-Seijo, P, Dauden, E, Descalzo, MA, Carretero, G, Carrascosa, JM, Vanaclocha, F et al.. Infections in Moderate to Severe Psoriasis Patients Treated with Biological Drugs Compared to Classic Systemic Drugs: Findings from the BIOBADADERM Registry. J Invest Dermatol. 2017;137 (2):313-321. doi: 10.1016/j.jid.2016.08.034. PubMed PMID:27677836 .
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  1. Tejera-Vaquerizo, A, Pérez-Cabello, G, Marínez-Leborans, L, Gallego, E, Oliver-Martínez, V, Martín-Cuevas, P et al.. Is mitotic rate still useful in the management of patients with thin melanoma?. J Eur Acad Dermatol Venereol. 2017;31 (12):2025-2029. doi: 10.1111/jdv.14485. PubMed PMID:28750139 .
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  1. Losantos, R, Funes-Ardoiz, I, Aguilera, J, Herrera-Ceballos, E, García-Iriepa, C, Campos, PJ et al.. Rational Design and Synthesis of Efficient Sunscreens To Boost the Solar Protection Factor. Angew Chem Int Ed Engl. 2017;56 (10):2632-2635. doi: 10.1002/anie.201611627. PubMed PMID:28128519 .
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  1. Belinchón, I, Ramos, JM, Carretero, G, Ferrándiz, C, Rivera, R, Daudén, E et al.. Adverse events associated with discontinuation of the biologics/classic systemic treatments for moderate-to-severe plaque psoriasis: data from the Spanish Biologics Registry, Biobadaderm. J Eur Acad Dermatol Venereol. 2017;31 (10):1700-1708. doi: 10.1111/jdv.14314. PubMed PMID:28485816 .
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  1. Pérez-Plaza, A, Carretero, G, Ferrandiz, C, Vanaclocha, F, Gómez-García, FJ, Herrera-Ceballos, E et al.. Comparison of phenotype, comorbidities, therapy and adverse events between psoriatic patients with and without psoriatic arthritis. Biobadaderm registry. J Eur Acad Dermatol Venereol. 2017;31 (6):1021-1028. doi: 10.1111/jdv.14188. PubMed PMID:28252811 .
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  1. Dávila-Seijo, P, Dauden, E, Descalzo, MA, Carretero, G, Carrascosa, JM, Vanaclocha, F et al.. Infections in Moderate to Severe Psoriasis Patients Treated with Biological Drugs Compared to Classic Systemic Drugs: Findings from the BIOBADADERM Registry. J Invest Dermatol. 2017;137 (2):313-321. doi: 10.1016/j.jid.2016.08.034. PubMed PMID:27677836 .
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  1. Tejera-Vaquerizo, A, Pérez-Cabello, G, Marínez-Leborans, L, Gallego, E, Oliver-Martínez, V, Martín-Cuevas, P et al.. Is mitotic rate still useful in the management of patients with thin melanoma?. J Eur Acad Dermatol Venereol. 2017;31 (12):2025-2029. doi: 10.1111/jdv.14485. PubMed PMID:28750139 .
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  1. Losantos, R, Funes-Ardoiz, I, Aguilera, J, Herrera-Ceballos, E, García-Iriepa, C, Campos, PJ et al.. Rational Design and Synthesis of Efficient Sunscreens To Boost the Solar Protection Factor. Angew Chem Int Ed Engl. 2017;56 (10):2632-2635. doi: 10.1002/anie.201611627. PubMed PMID:28128519 .
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  1. de Troya-Martín, M, Padilla-España, L, Férnandez-Morano, T, Delgado-Sánchez, N, Blázquez Sánchez, N, Rivas-Ruiz, F et al.. Sun Protection Habits and Attitudes Among Healthcare Personnel in a Mediterranean Population. J Cancer Educ. 2016;31 (4):789-795. doi: 10.1007/s13187-015-0913-1. PubMed PMID:26370806 .
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  1. Dávila-Seijo, P, Dauden, E, Carretero, G, Ferrandiz, C, Vanaclocha, F, Gómez-García, FJ et al.. Survival of classic and biological systemic drugs in psoriasis: results of the BIOBADADERM registry and critical analysis. J Eur Acad Dermatol Venereol. 2016;30 (11):1942-1950. doi: 10.1111/jdv.13682. PubMed PMID:27329511 .
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  1. Julià, A, Pinto, JA, Gratacós, J, Queiró, R, Ferrándiz, C, Fonseca, E et al.. A deletion at ADAMTS9-MAGI1 locus is associated with psoriatic arthritis risk. Ann Rheum Dis. 2015;74 (10):1875-81. doi: 10.1136/annrheumdis-2014-207190. PubMed PMID:25990289 .
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  1. Julià, A, Ferrándiz, C, Dauden, E, Fonseca, E, Fernández-López, E, Sanchez-Carazo, JL et al.. Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis. Pharmacogenomics J. 2015;15 (4):322-5. doi: 10.1038/tpj.2014.71. PubMed PMID:25403996 .
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  1. Tejera-Vaquerizo, A, Arias-Santiago, S, Nagore, E, Martín-Cuevas, P, Orgaz-Molina, J, Traves, V et al.. Defining the dermoscopic characteristics of fast-growing cutaneous melanomas. Melanoma Res. 2015;25 (3):269-72. doi: 10.1097/CMR.0000000000000157. PubMed PMID:25919929 .
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  1. Tejera-Vaquerizo, A, Nagore, E, Puig, S, Robert, C, Saiag, P, Martín-Cuevas, P et al.. Effect of time to sentinel-node biopsy on the prognosis of cutaneous melanoma. Eur J Cancer. 2015;51 (13):1780-93. doi: 10.1016/j.ejca.2015.05.023. PubMed PMID:26072362 PubMed Central PMC4768477.
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  1. de Gálvez, MV, Aguilera, J, Bernabó, JL, Sánchez-Roldán, C, Herrera-Ceballos, E. Human Hair as a Natural Sun Protection Agent: A Quantitative Study. Photochem Photobiol. ;91 (4):966-70. doi: 10.1111/php.12433. PubMed PMID:25682789 .
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  1. Carretero, G, Ferrandiz, C, Dauden, E, Vanaclocha Sebastián, F, Gómez-García, FJ, Herrera-Ceballos, E et al.. Risk of adverse events in psoriasis patients receiving classic systemic drugs and biologics in a 5-year observational study of clinical practice: 2008-2013 results of the Biobadaderm registry. J Eur Acad Dermatol Venereol. 2015;29 (1):156-63. doi: 10.1111/jdv.12492. PubMed PMID:24684267 .
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  1. Medina, C, Carretero, G, Ferrandiz, C, Dauden, E, Vanaclocha, F, Gómez-García, FJ et al.. Safety of classic and biologic systemic therapies for the treatment of psoriasis in elderly: an observational study from national BIOBADADERM registry. J Eur Acad Dermatol Venereol. 2015;29 (5):858-64. doi: 10.1111/jdv.12688. PubMed PMID:25185962 .
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