Endocrinología celular y molecular
Lineas de Investigación
01. Microflora intestinal, resistencia a la insulina y obesidad
02. Adipobiología en sujetos con fenotipos discordantes obesidad-diabetes
03. Efecto metabólico de la cirugía bariátrica
04. Factores ambientales en la génesis de obesidad y diabetes.
05. Nuevos mecanismos en la relación obesidad / cáncer
06. Análisis de los efectos de la lipemia postprandial en el metabolismo del tejido adiposo
07. Factores genéticos y epigenéticos en la prevención, evolución y tratamiento de la diabetes gestacional.
08. Estudio PREDIMED PLUS.
09 Abordaje dietoterápico de la obesidad: papel de la cetosis, ayuno intermitente, ejercicio físico y cronobiología.
10. Fitness mitocondrial en enfermedades metabólicas.
11. Complicaciones endocrino-metabólicas de la obesidad: Hipogonadismo masculino e hígado graso.
12. Hiperlipoproteinemia, resistencia a la insulina y enfermedad aterosclerótica.
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Tecnico Laboratorio
- Otro
Proyectos de Investigación
Plataforma de Biobanco y Biomodelos Animales y 3D de Málaga. 2021-2023 Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades.
Instituto de Salud Carlos III, Ministerio de Ciencia, Innovación y Universidades.
Plataforma de Biobanco y Biomodelos Animales y 3D de Málaga
2021
Avances en medicina de precisión de la obesidad: Análisis multiómico y dinámico para el descubrimiento y validación de biomarcadores predictores de pérdida de peso tras intervención en personas de alto riesgo
Instituto de Salud Carlos III (ISCIII)
Proyectos de Investigación de Medicina Personalizada de Precisión de la Acción Estratégica en Salud 2017-2020
2022
PT20/00101 Plataforma Biobanco y Biomodelos
Instituto de Salud Carlos III
.
2020
Papel de los cuerpos cetónicos y la microbiota en el abordaje dietético de la obesidad. Proyecto secundario: Impacto de la obesidad y sus comorbilidades en el pronóstico y evolución de la enfermedad COVID-19
Consejería de Salud y Familias
.
2020
Molecular Genetics
Ministry of Science, Research and Technology (Islamic Republic)
.
2020
Solicitud para el refuerzo anual de la actividad investigadora en las unidades asistenciales del servicio andaluz de Salud (SAS)
Servicio Andaluz de Salud (SAS)
.
2020
Contratos Río Ortega 2020 Miiguel Damas Fuentes. Jefe de Grupo: Francisco J. Tinahones Madueño
Instituto de Salud Carlos III
.
2020
Contrato Predoctoral. Candidato: Hatim Boughanem Lakhal, Jefe de Grupo: Manuel Macías González
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
.
2020
Contratos Miguel Servet 2020 Almudena Ortega Gomez
Instituto de Salud Carlos III
.
2020
00040 Contratos Juan Rodes 2020 Maria Molina Vega
Instituto de Salud Carlos III
.
2020
Contratos Miguel Servet 2020 Carolina Gutierrez Repiso
Instituto de Salud Carlos III
.
2020
S1574165220315 LINEA DE AYUDAS PARA LA CAPTACIÓN, INCORPORACIÓN Y MOVILIDAD DE CAPITAL HUMANO DE I+D+i FRANCISCO TINAHONES MADUEÑO.
Consejería de Economía, Conocimiento, Empresas y Universidad
.
2019
ECT2019-000575 Promoción y coordinación de participación en H2020 del instituto de investigación biomédica de Málaga(IBIMA) y centros del sistema sanitario de Málaga
Agencia Estatal de Investigación
.
2019
A1-0052-2019 SOLICITUD PARA EL REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA (UGC) DEL SERVICIO ANDALUZ DE SALUD (SAS)
Servicio Andaluz de Salud (SAS)
.
2019
RB-0001-2019 RENOVACIÓN ACCION B CONVOCATORIA 2014 EN LAS UNIDADES DE GESTIÓN CLÍNICA (UGC) DEL SERVICIO ANDALUZ DE SALUD (SAS)
Servicio Andaluz de Salud (SAS)
.
2019
PI19/00507 Fitness mitocondrial diana para la terapia contra la prediabetes IP MORA MURRI PIERRI
ISCIII
.
2019
PI-0419-2019. Efecto de metformina sobre microbiota, inflamación, estrés oxidativo y su potenciales beneficios sobre la función célula β a través de cambios epigenéticos en diabetes gestacional.
Consejería de Salud y Familias
.
2019
JR19-00054 Contratos Juan Rodes 2019
ISCIII
.
2019
IJC2018-037733- IAYUDAS JUAN DE LA CIERVA – INCORPORACIÓN 2018
Agencia Estatal de Investigación
.
2019
ML4Microbiome – Statistical and machine learning techniques in human microbiome studies
Comisión Europea
.
2019
B-0001-2019 Acciones para el refuerzo con recursos humanos de la actividad investigadora en las unidades de Gestión clínica del Servicio Andaluz de Salud 2019.Acción B clínicos investigadores.
SAS
.
2019
FI19-00178 Contratos predoctorales de formación en investigación en salud
ISCIII
.
2019
FI19-00177 Contratos predoctorales de formación en investigación en salud
ISCIII
.
2019
MOV19-002 MicroARNs: modulación de la mitofagia en adipocitos
Instituto de Investigación Biomédica de Málaga (IBIMA)
.
2019
CAS19-00342 Estancia movilidad en el extranjero José Castillejo para jóvenes doctores 2019
Ministerio de Ciencia e Innovación
.
2019
CD19-00216 Contratos Sara Borrell 2019
ISCIII
.
2019
Albert Renold Travel Fellowship Programme 2019
European Association for the Study of Diabetes
.
2019
Microbiome and methylome relationship before and after a weight loss treatment in liquid biopsia from patients with obesity-related liver disease for the identification of liver risk biomarkers (ONCOHEPATOBESITY-MARK)
CIBEROBN - INSTITUTO DE SALUD CARLOS III
INTERCIBER
2018
CM18-00120 Contratos Río Hortega 2018 Maria Molina Vega Jefe del Grupo: Fernando Cardona Diaz
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA
2018
SED-2018-02 DIFERENCIAS EN MICROBIOTA ENTRE PACIENTES CON DIABETES MELLITUS GESTACIONAL TRATADAS CON INSULINA FRENTE A AQUELLAS TRATADAS CON METFORMINA Y SU POSIBLE PAPEL EN EL CONTROL METABÓLICO, LA INFLAMACIÓN Y LOS RESULTADOS OBSTÉTRICOS Y PERINATALES. IP: María Molina Vega
SOCIEDAD ESPAÑOLA DE DIABETES
AYUDAS SED A PROYECTOS DE INVESTIGACIÓN BÁSICA Y CLÍNICA EN DIABETES DIRIGIDOS POR JÓVENES INVESTIGADORES
2018
A-0033-2018 Acciones A. Intensificación SAS. Refuerzo Anual de la Actividad Investigadora en las Unidades de Gestión Clínica (UGC) del Servicio Andaluz de Salud 2018.Profesionales Propuestos: Francisco Tinahones Madueño
SERVICIO ANDALUZ DE SALUD
ACCIÓN A. REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UGC DEL SAS
2018
B-0033-2014 B-0034-2014 Refuerzo mediante contratos de larga duración de las UGC del SAS, para el desarrollo de programas de investigación, desarrollo e innovación.
SERVICIO ANDALUZ DE SALUD
REFUERZO MEDIANTE CONTRATOS DE LARGA DURACIÓN DE LAS UGC DEL SAS, PARA EL DESARROLLO DE PROGRAMAS DE I
2014
RIC-0539-2018: RED DE ENSAYOS CLÍNICOS EN METABOLISMO: DIABETES, OBESIDAD Y DISLIPEMIA
CONSEJERÍA DE SALUD
PROYECTOS INVESTIGACIÓN CLÍNICA EN RED CON FORTALECIMIENTO DEL CAPITAL HUMANO INVESTIGADOR
2018
PI18/01160 PAPEL DE LOS CUERPOS CETONICOS Y LA MICROBIOTA EN EL ABORDAJE DIETETICO DE LA OBESIDAD
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
PI15/01114 Modificaciones epigenéticas y microbiota en la génesis de la disfunción del tejido adiposo y la resistencia a la insulina.
INSTITUTO DE SALUD CARLOS III
PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2015
FJCI-2016-28173 JC Formacion 2016. Medicina Clínica y epidemiología
MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS JUAN DE LA CIERVA FORMACIÓN
2017
PI-0151-2018: Papel de la microbiota intestinal en la patogénesis de la espondiloartritis axial radiográfica.
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
MS17/00133 Miguel Servet Tipo I
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2017
PI-0297-2018: MITOTERAPIA APLICADA A LA OBESIDAD Y SÍNDROME METABÓLICO
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
CP17/00133 Mitophagy in Adiposse tissue:getting at the heart of metabolic disorders
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2017
PI18/01175 Efecto de la diabetes gestacional sobre el epigenoma de la madre y de la descendencia en los 1000 primeros días. Identificación de potenciales biomarcadores epigenéticos de riesgo de DM2
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
PI15/01350 Cambios epigenéticos en la evolución del obeso metabólicamente sano. Búsqueda de nuevos biomarcadores. Estudio prospectivo y de intervención.
INSTITUTO DE SALUD CARLOS III
PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2015
CM17/00169 Rio Hortega 2017
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA
2017
PI-0283-2018: Patrón de metilación de ADN circulante como marcador de muerte de célula beta en diabetes gestacional. Búsqueda de biomarcadores de conversión de diabetes gestacional a diabetes tipo 2 en biopsia líquida.
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
RC-0001-2018 Acción C Nicolás Monardes Manuel Macias
SERVICIO ANDALUZ DE SALUD
RENOVACIÓN ACCIÓN C (PROGRAMA NICOLÁS MONARDES) DE LA CONVOCATORIA
2018
PI18/01399 Nuevo papel en la regulación epigenetica del sistema de la vitamina D y antagonistas de la vía Wnt-Bcatenin en obesidad y sus comorbilidades
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
CPII18-00030 Miguel Servet Tipo II 2018 Lourdes Garrido Sánchez
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO II
2018
MS13/00188 MIGUEL SERVET I CONTRATO: Efecto de las LDL oxidadas y anticuerpos anti-LDL oxidada sobre el metabolismo del adipocito y sobre la resistencia a la insulina
INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I
2013
PI-0194-2017 Nuevos Biomarcadores de Respuesta Precoz y Tardía A la Pérdida de Peso Tras la Cirugía Bariátrica
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2017
PI17/01407 Nuevos biomarcadores de respuesta precoz y tardía a la pérdida de peso tras la cirugía bariátrica
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2017
PI14/01306 Papel de las células endoteliales vasculares como mediadoras de la respuesta frente a la dieta
INSTITUTO DE SALUD CARLOS III
PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2014
MS16/00163 Contrato Miguel Servet Tipo I 2016 Isabel Moreno Indias
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2016
MdeOya-001-2017 Definiendo el papel de la microbiota intestinal en los beneficios para la salud reportados por el consumo de cerveza
CENTRO DE INFORMACIÓN CERVEZA Y SALUD
BECAS DE INVESTIGACIÓN MANUEL DE OYA. CERVEZA, SALUD Y NUTRICIÓN
2017
CP16/00163 Proyecto asociado Miguel Servet Tipo I 2016 Isabel Moreno Indias: Through the completely understanding of the mechanisms underlying the link between obesity and gut microbiota
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO I
2016
IJCI-2017-33065 JCI Carolina Gutiérrez Repiso Investigadora Candidata: Carolina Gutiérrez Repiso / Jefe de Grupo: Francisco José Tinahones Madueño Área Científica: Medicina Clínica y Epidemiología
MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS JUAN DE LA CIERVA INCORPORACIÓN
2018
PI-0334-2016 Papel de la Microbiota del Estómago y Yeyuno en la Obesidad y Diabetes Tipo 2. Asociación Con la Inflamación, Permeabilidad de la Membrana y Hormonas Gastrointestinales
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2016
Estudios Clínicos
Seguridad, tolerabilidad, farmacocinética y farmacodinámica de dosis subcutáneas únicas y múltiples de NNC0365-3769 (Mim8) en pacientes sanos y en pacientes con hemofilia A con o sin inhibidores del factor VIII. (FRONTIER 1).
NOVO NORDISK A/S
Fase: II
Ensayo Clínico Comercial
Estudio comparativo de fase IIb, abierto, aleatorizado, doble ciego, controlado con placebo y multicéntrico de la cotadutida en participantes con nefropatía crónica y diabetes mellitus de tipo 2 (CKD).
ASTRAZENECA AB MM
Fase: II
Ensayo Clínico Comercial
Antagonismo del receptor de glucocorticoides en el tratamiento del hipercortisolismo en pacientes con adenomas suprarrenales que secretan cortisol o hiperplasia (GRADIENT): Estudio de fase III, aleatorizado, doble ciego y comparado con placebo sobre la ef.
CORCEPT THERAPEUTICS INCORPORATED
Fase: III
Ensayo Clínico Comercial
Estudio de fase 2, aleatorizado, sin enmascaramiento, con un tratamiento comparativo y grupos paralelos, para evaluar la seguridad y la eficacia de LY3209590 en pacientes con diabetes mellitus de tipo 1 que anteriormente han recibido tratamiento con varia.
LILLY, S.A.U.
Fase: II
Ensayo Clínico Comercial
Comparación del efecto de tirzepatida frente al de dulaglutida sobre los acontecimientos cardiovasculares mayores en pacientes con diabetes de tipo 2 (SURPASS-CVOT).
Lilly, S.A.U
Fase: III
Ensayo Clínico Comercial
Estudio de extensión sin enmascaramiento de la seguridad de relacorilant (CORT125134) en el tratamiento de los signos y síntomas del síndrome de Cushing endógeno.
CORCEPT THERAPEUTICS INCORPORATED
Fase: III
Ensayo Clínico Comercial
I8B-MC-ITSG. Estudio prospectivo, aleatorizado, doble ciego, en el que se comparan LY900014 y Fiasp®, ambos en combinación con insulina basal, en adultos con diabetes de tipo 1PRONTO-Compare
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
FIM-MET-2015-01. Eficacia del tratamiento con metformina en diabetes gestacional no controlada con dieta frente al uso de insulinoterapia.Estudio MeDiGes.
FUNDACION PÚBLICA ANDALUZA PARA LA INVESTIGACION DE MALAGA EN BIOMEDICINA Y SALUD FIMABIS
Fase: IV
ENSAYO CLINICO INDEPENDIENTE
FPS-INSUPAR-2015-01. Insulina basal subcutanea versus intravenosa en pacientes diabéticos hospitalizados no criticos que reciben nutricion parental total
FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD
Fase: IV
ENSAYO CLINICO INDEPENDIENTE
THR-1442-C-480. Estudio en fase 3, aleatorizado, controlado con elemento activo, doble ciego para evaluar los efectos de bexagliflozina en comparación con glimepirida en sujetos con diabetes mellitus tipo 2 que tienen un control glucémico inadecuado con metformina.
THERACOS SUB, LLC
Fase: III
ENSAYO CLINICO COMERCIAL
THR-1442-C-448. Estudio doble ciego, controlado con placebo para evaluar el efecto de los comprimidos de bexagliflozina sobre la hemoglobina A1c en pacientes con diabetes mellitus de tipo 2 e insuficiencia renal moderada
THERACOS SUB, LLC
Fase: III
ENSAYO CLINICO COMERCIAL
NN9924-4221. PIONEER 6 Resultados cardiovasculares. Ensayo para investigar la seguridad cardiovascular de semaglutida oral en sujetos con diabetes tipo 2
NOVO NORDISK A/S
Fase: III
ENSAYO CLINICO COMERCIAL
NN9828-4150. Ensayo clínico demostrativo preliminar, multicéntrico, aleatorizado, doble ciego, doble enmascarado, controlado con placebo y de grupos paralelos en sujetos adultos con diabetes mellitus tipo 1 recién diagnosticada para investigar el efecto de NNC0114-000
NOVO NORDISK A/S
Fase: II
ENSAYO CLINICO COMERCIAL
NN9536-4374. Efecto y seguridad de semaglutida 2,4 mg una vez a la semana en sujetos con sobrepeso u obesidad y diabetes tipo 2
NOVO NORDISK A/S
Fase: III
ENSAYO CLINICO COMERCIAL
NN9535-4386. Efecto de semaglutida una vez a la semana frente a insulin aspart tres veces al día, ambas añadidas a metformina e insulina glargina optimizada (U100), en sujetos con diabetes tipo 2 Ensayo de 52 semanas, multicéntrico, multinacional, abierto, con contro
NOVO NORDISK A/S
Fase: III
ENSAYO CLINICO COMERCIAL
LIRALUNG. Ensayo clínico multicéntrico, aleatorizado, doble ciego, cruzado y controlado con placebo para evaluar el efecto de Liraglutida sobre la función pulmonar de pacientes con diabetes mellitus tipo 2 (Estudio LIRALUNG)
ALBERT LECUBE TORELLO
Fase: IV
ENSAYO CLINICO COMERCIAL
I8B-MC-ITRM. Estudio prospectivo, aleatorizado y doble ciego, en el que se compara LY900014 con la insulina lispro, con un grupo abierto en el que se administra LY900014 posprandial, en combinación con insulina glargina o insulina degludec, en adultos con diabetes de
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
H9X-MC-GBGL. Estudio aleatorizado, doble ciego y con grupos paralelos para evaluar la eficacia y la seguridad de las dosis de dulaglutida en investigación cuando se añaden al tratamiento con metformina en pacientes con diabetes mellitus tipo 2
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
GLP116174. Estudio a largo plazo, aleatorizado, doble ciego, controlado con placebo para determinar el efecto de Albiglutida, cuando se añade al tratamiento hipoglucemiante estándar, sobre eventos cardiovasculares mayores en pacientes con Diabetes Mellitus Tipo2
GLAXOSMITHKLINE, S.A.
Fase: IV
ENSAYO CLINICO COMERCIAL
GL-GLAT1-3001. Estudio en fase III, abierto, aleatorizado y multicéntrico, para comparar la inmunogenicidad, eficacia y seguridad de la inyección de insulina glargina de Gan & Lee Pharmaceuticals con Lantus® (inyección de insulina glargina) en sujetos adultos con diabet
GAN & LEE PHARMACEUTICALS
Fase: III
ENSAYO CLINICO COMERCIAL
EFC15166. Estudio multicéntrico, aleatorizado, con enmascaramiento doble, de tres grupos paralelos controlados con placebo de 52 semanas de duración para evaluar la eficacia y la seguridad de sotagliflozina en pacientes con diabetes mellitus de tipo 2 e insuficienc
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
EFC14867. Estudio de 26 semanas aleatorizado, doble ciego, controlado, multicéntrico con grupos paralelos para evaluar la eficacia y seguridad de sotagliflozina en comparación con empagliflozina y placebo en pacientes con diabetes de tipo 2 que tienen un control gl
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
EFC13794. Estudio abierto, de 26 semanas de duración, para evaluar la eficacia y seguridad de la combinación en proporción fija de insulina glargina/lixisenatida en adultos con Diabetes Tipo 2 no controlados adecuadamente con un agonista del receptor de GLP-1 y met
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
DRI13940. Estudio en Fase II, Aleatorizado, de Doble Ciego, Controlado con Placebo, de Escalada de Dosis, de 26 Semanas de Duración, para Evaluar la Seguridad y la Eficacia de Estudio en Fase II, Aleatorizado, de Doble Ciego, Controlado con Placebo, de Escalada de
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: II
ENSAYO CLINICO COMERCIAL
D169AC00001. Ensayo Clínico para Evaluar el Efecto de Dapagliflozina sobre el Riesgo de Eventos Renales y Mortalidad Cardiovascular en Pacientes con Enfermedad Renal Crónica.
ASTRAZENECA AB
Fase: III
ENSAYO CLINICO COMERCIAL
BCB109. Ensayo clínico aleatorizado, controlado con placebo, para evaluar los resultados clínicos cardiovasculares tras el tratamiento con Exenatida una vez a la semana en pacientes con Diabetes Mellitus de tipo 2
AMYLIN PHARMACEUTICALS INC.
Fase: III
ENSAYO CLINICO COMERCIAL
28431754DNE3001. Estudio aleatorizado, doble ciego, motivado por los acontecimientos, controlado con placebo y multicéntrico, de los efectos de la canagliflozina en los resultados renales y cardiovasculares en sujetos con diabetes mellitus tipo 2 y nefropatía diabética
JANSSEN-CILAG, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
28431754DIA4003. Ensayo Randomizado, Multicéntrico, Doble ciego, Paralelo, Controlado con Placebo, de los efectos de la Canaglifozina en eventos renales, en sujetos adultos con Diabetes Mellitus Tipo II
JANSSEN-CILAG, S.A.
Fase: IV
ENSAYO CLINICO COMERCIAL
1218.22. Estudio multicéntrico, internacional, aleatorizado, en grupos paralelos, doble ciego y controlado con placebo sobre seguridad cardiovascular y resultados microvasculares renales con linagliptina, administrada en dosis de 5 mg una vez al día en pacientes c
BOEHRINGER INGELHEIM ESPAÑA, S.A.
Fase: IV
ENSAYO CLINICO COMERCIAL
I8B-MC-ITRN. Protocolo I8B-MC-ITRNEstudio prospectivo, aleatorizado y doble ciego en el que se compara LY900014 con insulina lispro, ambos en combinación con insulina glargina o insulina degludec, en adultos con diabetes de tipo 2 PRONTO-T2D
LILLY, S.A.
Fase: III
ENSAYO CLINICO COMERCIAL
EFC14837. Estudio multicéntrico, aleatorizado, con enmascaramiento doble, de tres grupos paralelos controlados con placebo de 52 semanas de duración para evaluar la eficacia y la seguridad de sotagliflozina en pacientes con diabetes mellitus de tipo 2 e insuficienc
SANOFI AVENTIS RECHERCHE & DEVELOPPEMENT
Fase: III
ENSAYO CLINICO COMERCIAL
Patentes y Tecnologías
Biomarcadores epigenéticos para el diagnóstico y prevención de la evolución de la obesidad
Morcillo Espina, María Sonsoles
Rojo Martinez, Gemma
Linares Pineda, Teresa María
Gutierrez Repiso, Carolina
Tinahones Madueño, Francisco José
González Jiménez, Andrés
Valdés Hernández, Sergio
Rojo Martinez, Gemma
Linares Pineda, Teresa María
Gutierrez Repiso, Carolina
Tinahones Madueño, Francisco José
González Jiménez, Andrés
Valdés Hernández, Sergio
Gutierrez Repiso, Carolina
Tinahones Madueño, Francisco José
González Jiménez, Andrés
Valdés Hernández, Sergio
González Jiménez, Andrés
Valdés Hernández, Sergio
Medicina de precisión para el tratamiento de la obesidad
Said Lhamyani
Tinahones Madueño, Francisco José
el Bekay Rizky, Rajaa
Gentile, Adriana Mariel
Tinahones Madueño, Francisco José
el Bekay Rizky, Rajaa
Gentile, Adriana Mariel
Gentile, Adriana Mariel
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
Gut microbiota of patients with type 2 diabetes and gastrointestinal intolerance to metformin differs in composition and functionality from tolerant patients
Díaz-Perdigones CM, Muñoz-Garach A, Álvarez-Bermúdez MD, Moreno-Indias I, Tinahones FJ Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145():112448
Metformin action over gut microbiota is related to weight and glycemic control in gestational diabetes mellitus: A randomized trial
Molina-Vega M, Picón-César MJ, Gutiérrez-Repiso C, Fernández-Valero A, Lima-Rubio F, et al. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jan;145():112465
25-Hydroxyvitamin D status is associated with interleukin-6 methylation in adipose tissue from patients with colorectal cancer
Boughanem H, Ruiz-Limon P, Crujeiras AB, de Luque V, Tinahones FJ, et al. Food & function 2021 Oct 19;12(20):9620-9631
A lifestyle intervention with an energy-restricted Mediterranean diet and physical activity enhances HDL function: a substudy of the PREDIMED-Plus randomized controlled trial
Sanllorente A, Soria-Florido MT, Castañer O, Lassale C, Salas-Salvadó J, et al. The American journal of clinical nutrition 2021 Nov 8;114(5):1666-1674
An alcohol-free beer enriched with isomaltulose and a resistant dextrin modulates gut microbiome in subjects with type 2 diabetes mellitus and overweight or obesity: a pilot study
Mateo-Gallego, R; Moreno-Indias, I; Bea, AM; Sanchez-Alcoholado, L; Fumanal, AJ; Quesada-Molina, M; Prieto-Martin, A; Gutierrez-Repiso, C; Civeira, F; Tinahones, FJ FOOD & FUNCTION 2021
An Epigenetic Signature is Associated with Serum 25-Hydroxyvitamin D in Colorectal Cancer Tumors
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Applications of Machine Learning in Human Microbiome Studies: A Review on Feature Selection, Biomarker Identification, Disease Prediction and Treatment
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Assessment of price and nutritional quality of gluten-free products versus their analogues with gluten through the algorithm of the nutri-score front-of-package labeling system
de las Heras-Delgado, S; Alias-Guerrero, ADN; Cendra-Duarte, E; Salas-Salvado, J; Vilchez, E; Roger, E; Hernandez-Alonso, P; Babio, N FOOD & FUNCTION 2021
Association between ankle-brachial index and cognitive function in participants in the PREDIMED-Plus study: cross-sectional assessment
López M, Ríos A, Romaguera D, Martínez-González MÁ, Fernández-Aranda F, et al. Revista espanola de cardiologia (English ed.) 2021 Oct;74(10):846-853
Association between coffee consumption and total dietary caffeine intake with cognitive functioning: cross-sectional assessment in an elderly Mediterranean population
Paz-Graniel, I; Babio, N; Becerra-Tomas, N; Toledo, E; Camacho-Barcia, L; Corella, D; Castaner-Nino, O; Romaguera, D; Vioque, J; Alonso-Gomez, AM; Warnberg, J; Martinez, JA; Serra-Majem, L; Estruch, R; Tinahones, FJ; Fernandez-Aranda, F; Lapetra, J; Pinto, X; Tur, JA; Garcia-Rios, A; Bueno-Cavanillas, A; Gaforio, JJ; Matia-Martin, P; Daimiel, L; Sanchez, VM; Vidal, J; Prieto-Sanchez, L; Ros, E; Razquin, C; Mestres, C; Sorli, JV; Cuenca-Royo, AM; Rios, A; Torres-Collado, L; Vaquero-Luna, J; Perez-Farinos, N; Zulet, MA; Sanchez-Villegas, A; Casas, R; Bernal-Lopez, MR; Santos-Lozano, JM; Corbella, X; Mateos, D; Buil-Cosiales, P; Jimenez-Murcia, S; Fernandez-Carrion, R; Forcano-Gamazo, L; Lopez, M; Sempere-Pascual, MA; Moreno-Rodriguez, A; Gea, A; De la Torre-Fornell, R; Salas-Salvado, J EUROPEAN JOURNAL OF NUTRITION 2021
Blood Hemoglobin Substantially Modulates the Impact of Gender, Morbid Obesity, and Hyperglycemia on COVID-19 Death Risk: A Multicenter Study in Italy and Spain
Mayneris-Perxachs J, Russo MF, Ramos R, de Hollanda A, Arxé AA, et al. Frontiers in endocrinology 2021;12():741248
Editorial: Emerging Roles of the Gut Microbiota in the Pathogenesis of Metabolic Disorders.
Moreno-Indias I, Salgado-Somoza A, El Azzouzi H, Murri M Frontiers in endocrinology 2021;12():736371
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study
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Cognitive Functioning and Cortical Brain Thickness in Acromegaly Patients: A Pilot study
García-Casares N, Fernández-Andújar M, González-Molero I, Maraver-Selfa S, Gutiérrez-Bedmar M, et al. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2021 Jul 19;36(5):780-790
Consumption of caffeinated beverages and kidney function decline in an elderly Mediterranean population with metabolic syndrome
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Dairy consumption, plasma metabolites, and risk of type 2 diabetes
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Dietary folate intake and metabolic syndrome in participants of PREDIMED-Plus study: a cross-sectional study
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Dietary vitamin D intake and colorectal cancer risk: a longitudinal approach within the PREDIMED study
Hernandez-Alonso, P; Canudas, S; Boughanem, H; Toledo, E; Sorli, JV; Estruch, R; Castaner, O; Lapetra, J; Alonso-Gomez, AM; Gutierrez-Bedmar, M; Fiol, M; Serra-Majem, L; Pinto, X; Ros, E; Fernandez-Lazaro, CI; Ramirez-Sabio, JB; Fito, M; Portu-Zapirain, J; Macias-Gonzalez, M; Babio, N; Salas-Salvado, J EUROPEAN JOURNAL OF NUTRITION 2021
Napping, nocturnal sleep and adiposity
Garach, AM; Perez, AMG NUTRICION HOSPITALARIA 2021
Different Weight Loss Intervention Approaches Reveal a Lack of a Common Pattern of Gut Microbiota Changes
Gutiérrez-Repiso C, Molina-Vega M, Bernal-López MR, Garrido-Sánchez L, García-Almeida JM, et al. Journal of personalized medicine 2021 Feb 8;11(2):
Effect of an Intensive Weight-Loss Lifestyle Intervention on Kidney Function: A Randomized Controlled Trial
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Effect of dulaglutide 3.0 and 4.5 mg on weight in patients with type 2 diabetes: Exploratory analyses of AWARD-11
Bonora E, Frias JP, Tinahones FJ, Van J, Malik RE, et al. Diabetes, obesity & metabolism 2021 Oct;23(10):2242-2250
Effect on an Oral Nutritional Supplement with beta-Hydroxy-beta-methylbutyrate and Vitamin D on Morphofunctional Aspects, Body Composition, and Phase Angle in Malnourished Patients
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Effect on gut microbiota of a 1-y lifestyle intervention with Mediterranean diet compared with energy-reduced Mediterranean diet and physical activity promotion: PREDIMED-Plus Study
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Effects of Mosquito Microbiota on the Survival Cost and Development Success of Avian Plasmodium
Martínez-de la Puente J, Gutiérrez-López R, Díez-Fernández A, Soriguer RC, Moreno-Indias I, et al. Frontiers in microbiology 2020;11():562220
Epigenetic Biomarkers of Transition from Metabolically Healthy Obesity to Metabolically Unhealthy Obesity Phenotype: A Prospective Study
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Evidence-based recommendations of the Andalusian Group for Nutrition Reflection and Investigation (GARIN) for the management of adult patients with short bowel syndrome
Vílchez-López FJ, Larrán-Escandón L, García Almeida JM, Arraiza Irigoyen C, Irles Rocamora JA, et al. Nutricion hospitalaria 2021 Dec 9;38(6):1287-1303
Factors Related to Weight Loss Maintenance in the Medium-Long Term after Bariatric Surgery: A Review
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Fruit and Vegetable Consumption is Inversely Associated with Plasma Saturated Fatty Acids at Baseline in Predimed Plus Trial
Domínguez-López I, Marhuenda-Muñoz M, Tresserra-Rimbau A, Hernáez Á, Moreno JJ, et al. Molecular nutrition & food research 2021 Sep;65(17):e2100363
Genome Profiling of H3k4me3 Histone Modification in Human Adipose Tissue during Obesity and Insulin Resistance
Castellano-Castillo D, Ramos-Molina B, Oliva-Olivera W, Ocaña-Wilhelmi L, Queipo-Ortuño MI, et al. Biomedicines 2021 Sep 30;9(10):
Glycemic Dysregulations Are Associated With Worsening Cognitive Function in Older Participants at High Risk of Cardiovascular Disease: Two-Year Follow-up in the PREDIMED-Plus Study
Gómez-Martínez C, Babio N, Júlvez J, Becerra-Tomás N, Martínez-González MÁ, et al. Frontiers in endocrinology 2021;12():754347
Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial
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Gut Microbiota Metabolism of Bile Acids Could Contribute to the Bariatric Surgery Improvements in Extreme Obesity
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Gut Microbiota Profile and Changes in Body Weight in Elderly Subjects with Overweight/Obesity and Metabolic Syndrome
Atzeni A, Galié S, Muralidharan J, Babio N, Tinahones FJ, et al. Microorganisms 2021 Feb 10;9(2):
Gut Microbiota: The Missing Link Between Helicobacter pylori Infection and Metabolic Disorders?
Martin-Nuñez GM, Cornejo-Pareja I, Clemente-Postigo M, Tinahones FJ Frontiers in endocrinology 2021;12():639856
Heart Failure in Type 1 Diabetes: A Complication of Concern? A Narrative Review
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Helicobacter pylori Eradication Therapy Affect the Gut Microbiota and Ghrelin Levels
Martín-Núñez GM, Cornejo-Pareja I, Clemente-Postigo M, Tinahones FJ, Moreno-Indias I Frontiers in medicine 2021;8():712908
High Fruit and Vegetable Consumption and Moderate Fat Intake Are Associated with Higher Carotenoid Concentration in Human Plasma
Marhuenda-Muñoz M, Rinaldi de Alvarenga JF, Hernáez Á, Tresserra-Rimbau A, Martínez-González MÁ, et al. Antioxidants (Basel, Switzerland) 2021 Mar 17;10(3):
Human adipose tissue-derived stem cell paracrine networks vary according metabolic risk and after TNF alpha-induced death: An analysis at the single-cell level
Oliva-Olivera, W; Castellano-Castillo, D; von Meyenn, F; Cardona, F; Lonnberg, T; Tinahones, FJ METABOLISM-CLINICAL AND EXPERIMENTAL 2021
Impact of Genetic Polymorphism on Response to Therapy in Non-Alcoholic Fatty Liver Disease
Martínez-Montoro JI, Cornejo-Pareja I, Gómez-Pérez AM, Tinahones FJ Nutrients 2021 Nov 15;13(11):
Impact of the Gestational Diabetes Diagnostic Criteria during the Pandemic: An Observational Study
Molina-Vega M, Gutiérrez-Repiso C, Lima-Rubio F, Suárez-Arana M, Linares-Pineda TM, et al. Journal of clinical medicine 2021 Oct 24;10(21):
Influence of Factors Altering Gastric Microbiota on Bariatric Surgery Metabolic Outcomes
Gutiérrez-Repiso C, Moreno-Indias I, Martín-Núñez GM, Ho-Plagaro A, Ocaña-Wilhelmi L, et al. Microbiology spectrum 2021 Dec 22;9(3):e0053521
Influence of Obesity in the miRNome: miR-4454, a Key Regulator of Insulin Response Via Splicing Modulation in Prostate
Herrero-Aguayo, V; Jimenez-Vacas, JM; Saez-Martinez, P; Gomez-Gomez, E; Lopez-Canovas, JL; Garrido-Sanchez, L; Herrera-Martinez, AD; Garcia-Bermejo, L; Macias-Gonzalez, M; Lopez-Miranda, J; Castano, JP; Gahete, MD; Luque, RM JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 2021
Iodine Deficiency and Mortality in Spanish Adults: Di@bet.es Study
Maldonado-Araque C, Valdés S, Badía-Guillén R, Lago-Sampedro A, Colomo N, et al. Thyroid : official journal of the American Thyroid Association 2021 Jan;31(1):106-114
Leading Factors for Weight Gain during COVID-19 Lockdown in a Spanish Population: A Cross-Sectional Study
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Lifestyle Modification Improves Insulin Resistance and Carotid Intima-Media Thickness in a Metabolically Healthy Obese Prepubescent Population
Gallardo-Escribano, C; Vargas-Candela, A; Vilches-Perez, A; Munoz-Melero, M; Ruiz-Moreno, MI; Benitez-Porres, J; Romance-Garcia, AR; Rodriguez-Ortega, R; Rosa-Lopez, A; Rosales-Jaime, A; Diaz-Ruiz, J; Tinahones, FJ; Gomez-Huelgas, R; Bernal-Lopez, MR JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION 2021
Lifestyle Modification Program on a Metabolically Healthy Elderly Population with Overweight/Obesity, Young-Old vs. Old-Old. CONSEQUENCES of COVID-19 Lockdown in This Program
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Longitudinal changes in adherence to the portfolio and DASH dietary patterns and cardiometabolic risk factors in the PREDIMED-Plus study
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Mediterranean, DASH, and MIND Dietary Patterns and Cognitive Function: The 2-Year Longitudinal Changes in an Older Spanish Cohort
Nishi SK, Babio N, Gómez-Martínez C, Martínez-González MÁ, Ros E, et al. Frontiers in aging neuroscience 2021;13():782067
Metabolomics of the tryptophan-kynurenine degradation pathway and risk of atrial fibrillation and heart failure: potential modification effect of Mediterranean diet
Razquin C, Ruiz-Canela M, Toledo E, Hernández-Alonso P, Clish CB, et al. The American journal of clinical nutrition 2021 Nov 8;114(5):1646-1654
Metformin for gestational diabetes study: metformin vs insulin in gestational diabetes: glycemic control and obstetrical and perinatal outcomes: randomized prospective trial
Picón-César MJ, Molina-Vega M, Suárez-Arana M, González-Mesa E, Sola-Moyano AP, et al. American journal of obstetrics and gynecology 2021 Nov;225(5):517.e1-517.e17
Microglial metabolism is a pivotal factor in sexual dimorphism in Alzheimer’s disease
Guillot-Sestier MV, Araiz AR, Mela V, Gaban AS, O’Neill E, et al. Communications biology 2021 Jun 10;4(1):711
Milk and Dairy Products Intake Is Related to Cognitive Impairment at Baseline in Predimed Plus Trial
Munoz-Garach, A; Cornejo-Pareja, I; Martinez-Gonzalez, MA; Bullo, M; Corella, D; Castaner, O; Romaguera, D; Vioque, J; Alonso-Gomez, AM; Warnberg, J; Martinez, JA; Serra-Majem, L; Estruch, R; Bernal-Lopez, MR; Lapetra, J; Pinto, X; Tur, JA; Lopez-Miranda, J; Bueno-Cavanillas, A; Delgado-Rodriguez, M; Matia-Martin, P; Daimiel, L; Sanchez, VM; Vidal, J; Prieto, L; Ros, E; Fernandez-Aranda, F; Camacho-Barcia, L; Ortega-Azorin, C; Soria, M; Fiol, M; Compan-Gabucio, L; Goicolea-Guemez, L; Perez-Lopez, J; Goni, N; Perez-Cabrera, J; Sacanella, E; Fernandez-Garcia, JC; Miro-Moriano, L; Gimenez-Gracia, M; Razquin, C; Paz-Graniel, I; Guillem, P; Zomeno, MD; Monino, M; Oncina-Canovas, A; Salaverria-Lete, I; Toledo, E; Salas-Salvado, J; Schroder, H; Tinahones, FJ MOLECULAR NUTRITION & FOOD RESEARCH 2021
miR-21 mimic blocks obesity in mice: A novel therapeutic option
Lhamyani S, Gentile AM, Giráldez-Pérez RM, Feijóo-Cuaresma M, Romero-Zerbo SY, et al. Molecular therapy. Nucleic acids 2021 Dec 3;26():401-416
Moderate Consumption of Beer and Its Effects on Cardiovascular and Metabolic Health: An Updated Review of Recent Scientific Evidence
Marcos A, Serra-Majem L, Pérez-Jiménez F, Pascual V, Tinahones FJ, et al. Nutrients 2021 Mar 9;13(3):
Modulation of Telomere Length by Mediterranean Diet, Caloric Restriction, and Exercise: Results from PREDIMED-Plus Study
Fernández de la Puente M, Hernández-Alonso P, Canudas S, Marti A, Fitó M, et al. Antioxidants (Basel, Switzerland) 2021 Oct 12;10(10):
Molecular Changes in the Adipose Tissue Induced by Rheumatoid Arthritis: Effects of Disease-Modifying Anti-Rheumatic Drugs
Arias de la Rosa I, Escudero-Contreras A, Ruiz-Ponce M, Román-Rodríguez C, Pérez-Sánchez C, et al. Frontiers in immunology 2021;12():744022
Morphofunctional assessment of patient’s nutritional status: a global approach
Almeida, JMG; Garcia, CG; Aguilar, IMV; Castaneda, VB; Guerrero, DB NUTRICION HOSPITALARIA 2021
NGS of microRNAs Involved in Cardioprotection Induced by Sevoflurane Compared to Propofol in Myocardial Revascularization Surgery: The ACDHUVV-16 Clinical Trial
Orriach, JLG; Belmonte, JJE; Aliaga, MR; Fernandez, AR; Capitan, MJR; Munoz, GQ; Ponferrada, AR; Torres, JA; Santiago-Fernandez, C; Gonzalez, EM; Navarro, MR; Bautista, R; Maldonado, JG; Garrido-Sanchez, L; Manas, JC CURRENT MEDICINAL CHEMISTRY 2021
Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges
Kuchay MS, Martínez-Montoro JI, Choudhary NS, Fernández-García JC, Ramos-Molina B Biomedicines 2021 Sep 28;9(10):
Nut consumption and type 2 diabetes risk: a systematic review and meta-analysis of observational studies
Becerra-Tomas, N; Paz-Graniel, I; Hernandez-Alonso, P; Jenkins, DJA; Kendall, CWC; Sievenpiper, JL; Salas-Salvado, J AMERICAN JOURNAL OF CLINICAL NUTRITION 2021
Oxidized LDL Increase the Proinflammatory Profile of Human Visceral Adipocytes Produced by Hypoxia
Santiago-Fernández C, Martín-Reyes F, Tome M, Gutierrez-Repiso C, Fernandez-Garcia D, et al. Biomedicines 2021 Nov 18;9(11):
Physical activity and metabolic syndrome severity among older adults at cardiovascular risk: 1-Year trends
Gallardo-Alfaro L, Bibiloni MDM, Bouzas C, Mascaró CM, Martínez-González MÁ, et al. Nutrition, metabolism, and cardiovascular diseases : NMCD 2021 Sep 22;31(10):2870-2886
Plasma Metabolomic Profiles of Glycemic Index, Glycemic Load, and Carbohydrate Quality Index in the PREDIMED Study
Bulló M, Papandreou C, Ruiz-Canela M, Guasch-Ferré M, Li J, et al. The Journal of nutrition 2021 Jan 4;151(1):50-58
Potential Role and Impact of Peripheral Blood Mononuclear Cells in Radiographic Axial Spondyloarthritis-Associated Endothelial Dysfunction
Ruiz-Limon P, Ladehesa-Pineda ML, Lopez-Medina C, Lopez-Pedrera C, Abalos-Aguilera MC, et al. Diagnostics (Basel, Switzerland) 2021 Jun 4;11(6):
Potential Role of Insulin Growth-Factor-Binding Protein 2 as Therapeutic Target for Obesity-Related Insulin Resistance
Boughanem H, Yubero-Serrano EM, López-Miranda J, Tinahones FJ, Macias-Gonzalez M International journal of molecular sciences 2021 Jan 24;22(3):
Psychological and metabolic risk factors in older adults with a previous history of eating disorder: A cross-sectional study from the Predimed-Plus study
Vintro-Alcaraz, C; Baenas, I; Lozano-Madrid, M; Granero, R; Ruiz-Canela, M; Babio, N; Corella, D; Fito, M; Martinez, JA; Alonso-Gomez, AM; Warnberg, J; Vioque, J; Romaguera, D; Lopez-Miranda, J; Estruch, R; Bernal-Lopez, MR; Lapetra, J; Sanchez-Villegas, A; Bueno-Cavanillas, A; Tur, JA; Martin-Sanchez, V; Pinto, X; Delgado-Rodriguez, M; Matia-Martin, P; Vidal, J; Cardenas, JJ; Daimiel, L; Ros, E; Razquin, C; Diaz-Lopez, A; Gonzalez, JI; Forcano, L; Zulet, MD; Bello-Mora, MC; Valenzuela-Guerrero, S; de la Hera, MG; Konieczna, J; Garcia-Rios, A; Casas, R; Gomez-Perez, AM; Garcia-Arellano, A; Bullo, M; Sorli, JV; Cuenca-Royo, A; Abete, I; Salaverria-Lete, I; Basterra-Gortari, FJ; de la Torre, R; Salas-Salvado, J; Fernandez-Aranda, F EUROPEAN EATING DISORDERS REVIEW 2021
Rate of non-invasive follicular thyroid neoplasms with papillary-like nuclear features depends on pathologist’s criteria: a multicentre retrospective Southern European study with prolonged follow-up
Paja M, Zafón C, Iglesias C, Ugalde A, Cameselle-Teijeiro JM, et al. Endocrine 2021 Jul;73(1):131-140
Recovery of parathyroid function in patients with thyroid cancer treated by total thyroidectomy: An analysis of 685 patients with hypoparathyroidism at discharge of surgery
Diez, JJ; Anda, E; Sastre, J; Perez-Corral, B; Alvarez-Escola, C; Manjon, L; Paja, M; Sambo, M; Santiago-Fernandez, P; Blanco-Carrera, C; Galofre, JC; Navarro, E; Zafon, C; Sanz, E; Oleaga, A; Bandres, O; Donnay, S; Megia, A; Picallo, M; Sanchez-Ragnarsson, C; Baena-Nieto, G; Fernandez-Garcia, JC; Lecumberri, B; de la Vega, MS; Romero-Lluch, AR; Iglesias, P ENDOCRINOLOGIA DIABETES Y NUTRICION 2021
Obesity and COVID-19. A necessary position statement
Bretón I, de Hollanda A, Vilarrasa N, Rubio Herrera MA, Lecube A, et al. Endocrinologia, diabetes y nutricion 2021 Oct;68(8):573-576
Shifts in gut microbiota and their metabolites induced by bariatric surgery. Impact of factors shaping gut microbiota on bariatric surgery outcomes
Gutiérrez-Repiso C, Moreno-Indias I, Tinahones FJ Reviews in endocrine & metabolic disorders 2021 Dec;22(4):1137-1156
Statistical and Machine Learning Techniques in Human Microbiome Studies: Contemporary Challenges and Solutions
Moreno-Indias I, Lahti L, Nedyalkova M, Elbere I, Roshchupkin G, et al. Frontiers in microbiology 2021;12():635781
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes
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Transdiagnostic Perspective of Impulsivity and Compulsivity in Obesity: From Cognitive Profile to Self-Reported Dimensions in Clinical Samples with and without Diabetes
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Effects of SHBG rs1799941 Polymorphism on Free Testosterone Levels and Hypogonadism Risk in Young Non-Diabetic Obese Males
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Epigenetic Influences in the Obesity/Colorectal Cancer Axis: A Novel Theragnostic Avenue
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Long Daytime Napping Is Associated with Increased Adiposity and Type 2 Diabetes in an Elderly Population with Metabolic Syndrome
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Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study
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Metabolic and Endocrine Consequences of Bariatric Surgery
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miR-20b, miR-296, and Let-7f Expression in Human Adipose Tissue is Related to Obesity and Type 2 Diabetes
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Molecular Characterization of Monocyte Subsets Reveals Specific and Distinctive Molecular Signatures Associated With Cardiovascular Disease in Rheumatoid Arthritis
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New molecular biomarkers in differentiated thyroid carcinoma: Impact of miR-146, miR-221 and miR-222 levels in the evolution of the disease
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Novel SFRP2 DNA Methylation Profile Following Neoadjuvant Therapy in Colorectal Cancer Patients with Different Grades of BMI
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Recommendations of the GARIN group for dietary managing of patient with chronic kidney disease
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Reduced Plasma Orexin-A Concentrations are Associated with Cognitive Deficits in Anorexia Nervosa
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Sheep and goats raised in mixed flocks have diverse immune status around parturition
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Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing
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Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk
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The Antagonist Effect of Arachidonic Acid on GLUT4 Gene Expression by Nuclear Receptor Type II Regulation
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The Expression/Methylation Profile of Adipogenic and Inflammatory Transcription Factors in Adipose Tissue Are Linked to Obesity-Related Colorectal Cancer
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The presence and suppressive activity of myeloid-derived suppressor cells are potentiated after interferon-beta treatment in a murine model of multiple sclerosis
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Total and Subtypes of Dietary Fat Intake and Its Association with Components of the Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Risk
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Transcriptional Analysis of FOXO1, C/EBP-alpha and PPAR-gamma 2 Genes and Their Association with Obesity-Related Insulin Resistance
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Trends in Diabetes-Related Potentially Preventable Hospitalizations in Adult Population in Spain, 1997-2015: A Nation-Wide Population-Based Study
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Type 2 Diabetes Is Associated with a Different Pattern of Serum Polyamines: A Case-Control Study from the PREDIMED-Plus Trial
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Vitamin D Status, Calcium Intake and Risk of Developing Type 2 Diabetes: An Unresolved Issue
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Adipose tissue inflammation and VDR expression and methylation in colorectal cancer
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Adipose Tissue LPL Methylation is Associated with Triglyceride Concentrations in the Metabolic Syndrome
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Alirocumab safety in people with and without diabetes mellitus: pooled data from 14 ODYSSEY trials
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Alirocumab vs usual lipid-lowering care as add-on to statin therapy in individuals with type 2 diabetes and mixed dyslipidaemia: The ODYSSEY DM-DYSLIPIDEMIA randomized trial
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Characterization of Metabolomic Profile Associated with Metabolic Improvement after Bariatric Surgery in Subjects with Morbid Obesity
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Chromatin immunoprecipitation improvements for the processing of small frozen pieces of adipose tissue
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Circulating Tumor Cells as a Biomarker of Survival and Response to Radium-223 Therapy: Experience in a Cohort of Patients With Metastatic Castration-Resistant Prostate Cancer
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Complement Factor C3 Methylation and mRNA Expression Is Associated to BMI and Insulin Resistance in Obesity
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Cross-sectional associations of objectively-measured sleep characteristics with obesity and type 2 diabetes in the PREDIMED-Plus trial
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Decreased blood pressure is related to changes in NF-kB promoter methylation levels after bariatric surgery
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Decreased GPIHBP1 protein levels in visceral adipose tissue partly underlie the hypertriglyceridemic phenotype in insulin resistance
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Dietary Intake in Population with Metabolic Syndrome: Is the Prevalence of Inadequate Intake Influenced by Geographical Area? Cross-Sectional Analysis from PREDIMED-Plus Study
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Differences in the neovascular potential of thymus versus subcutaneous adipose-derived stem cells from patients with myocardial ischaemia
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Differential effects of restrictive and malabsorptive bariatric surgery procedures on the serum lipidome in obese subjects.
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Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): a 24-week, randomised, double-blind, placebo-controlled trial
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Effectiveness of the physical activity intervention program in the PREDIMED-Plus study: a randomized controlled trial
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Elevated circulating levels of succinate in human obesity are linked to specific gut microbiota
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Fermented dairy products, diet quality, and cardio-metabolic profile of a Mediterranean cohort at high cardiovascular risk
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Gut Microbiota Differs in Composition and Functionality Between Children With Type 1 Diabetes and MODY2 and Healthy Control Subjects: A Case-Control Study
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Hyperphagia and Obesity in Prader-Willi Syndrome: PCSK1 Deficiency and Beyond?
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Impact in Plasma Metabolome as Effect of Lifestyle Intervention for Weight-Loss Reveals Metabolic Benefits in Metabolically Healthy Obese Women
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Implications of the Mediterranean diet and physical exercise on the lipid profile of metabolically healthy obese women as measured by nuclear magnetic resonance spectroscopy (H-1 NMR)
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Inflammatory gene expression in adipose tissue according to diagnosis of anxiety and mood disorders in obese and non-obese subjects
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Involvement of acetyl-CoA-producing enzymes in the deterioration of the functional potential of adipose-derived multipotent cells from subjects with metabolic syndrome.
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Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study
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Mediterranean Diet Supplemented With Coenzyme Q(10) Modulates the Postprandial Metabolism of Advanced Glycation End Products in Elderly Men and Women
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New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility
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Pharmacokinetic drug evaluation of exenatide for the treatment of type 2 diabetes
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Quantitative evaluation of capillaroscopic microvascular changes in patients with established coronary heart disease
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Radiotherapy in soft-tissue sarcoma of the extremities
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Role of Oral Nutritional Supplements Enriched with B-hydroxy-B-Methylbutyrate in Maintaining Muscle Function and Improving Clinical Outcomes in Various Clinical Settings
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Seafood Consumption, Omega-3 Fatty Acids Intake, and Life-Time Prevalence of Depression in the PREDIMED-Plus Trial.
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The caveolae-associated coiled-coil protein, NECC2, regulates insulin signalling in Adipocytes
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Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery
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BIM-23A760 influences key functional endpoints in pituitary adenomas and normal pituitaries: molecular mechanisms underlying the differential response in adenomas
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Brain Functional Connectivity Is Modified by a Hypocaloric Mediterranean Diet and Physical Activity in Obese Women
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CD36 overexpression: a possible etiopathogenic mechanism of atherosclerosis in patients with prediabetes and diabetes
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Changes in SCD gene DNA methylation after bariatric surgery in morbidly obese patients are associated with free fatty acids
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Characterization of lipid profile by nuclear magnetic resonance spectroscopy (H-1 NMR) of metabolically healthy obese women after weight loss with Mediterranean diet and physical exercise
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Design and rationale of the ODYSSEY DM-DYSLIPIDEMIA trial: lipid-lowering efficacy and safety of alirocumab in individuals with type 2 diabetes and mixed dyslipidaemia at high cardiovascular risk
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Dietary fat quantity and quality modifies advanced glycation end products metabolism in patients with metabolic syndrome
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Different response to hypoxia of adipose-derived multipotent cells from obese subjects with and without metabolic syndrome
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Effect of Dietary Lipids on Endotoxemia Influences Postprandial Inflammatory Response
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Efficacy and safety of alirocumab in insulin-treated patients with type 1 or type 2 diabetes and high cardiovascular risk: Rationale and design of the ODYSSEY DM-INSULIN trial
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Evaluation of a New Digital Automated Glycemic Pattern Detection Tool
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Expression of epicardial adipose tissue thermogenic genes in patients with reduced and preserved ejection fraction heart failure
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Expression of Sterol Regulatory Element-Binding Proteins in epicardial adipose tissue in patients with coronary artery disease and diabetes mellitus: preliminary study
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Fgf21 is required for cardiac remodeling in pregnancy
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Functional analysis of PCSK2 coding variants: A founder effect in the Old Order Amish population
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Ghrelin levels could be involved in the improvement of insulin resistance after bariatric surgery
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Growth hormone-releasing hormone is produced by adipocytes and regulates lipolysis through growth hormone receptor
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How Can a Good Idea Fail? Basal Insulin Peglispro [LY2605541] for the Treatment of Type 2 Diabetes
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IGFBP-3 Interacts with the Vitamin D Receptor in Insulin Signaling Associated with Obesity in Visceral Adipose Tissue
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Improving efficacy and efficiency through the implementation of a new organisational model in a Radiation Oncology Department
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Iodine is associated to semen quality in men who undergo consultations for infertility
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Jejunal gluconeogenesis associated with insulin resistance level and its evolution after Roux-en-Y gastric bypass
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Leisure-time physical activity, sedentary behaviors, sleep, and cardiometabolic risk factors at baseline in the PREDIMED-PLUS intervention trial: A cross-sectional analysis
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Linagliptin as add-on to empagliflozin and metformin in patients with type 2 diabetes: Two 24-week randomized, double-blind, double-dummy, parallel-group trials
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Lixisenatide in patients with type 2 diabetes and obesity: Beyond glycaemic control
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Methylation patterns of Vegfb promoter are associated with gene and protein expression levels: the effects of dietary fatty acids
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Molecular effect of fenofibrate on PBMC gene transcription related to lipid metabolism in patients with metabolic syndrome
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Neovascular deterioration, impaired NADPH oxidase and inflammatory cytokine expression in adipose-derived multipotent cells from subjects with metabolic syndrome
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Nitrogenous content in parenteral nutrition: a four-year experience in a general hospital. Critically-ill patient specificity
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No effect of different bariatric surgery procedures on LINE-1 DNA methylation in diabetic and nondiabetic morbidly obese patients
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Obesity and menopause modify the epigenomic profile of breast cancer
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Peculiarities of the obese patient with cancer: a national consensus statement by the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology
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Plasma FGF21 levels in obese patients undergoing energy-restricted diets or bariatric surgery: a marker of metabolic stress?
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Population-Based National Prevalence of Thyroid Dysfunction in Spain and Associated Factors: Di@bet.es Study
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Reference Values for TSH may be Inadequate to Define Hypothyroidism in Persons with Morbid Obesity: Di@bet.es Study
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Role of Gut Microbiota on Cardio-Metabolic Parameters and Immunity in Coronary Artery Disease Patients with and without Type-2 Diabetes Mellitus
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Serum metabolites in non-alcoholic fatty-liver disease development or reversion; a targeted metabolomic approach within the PREDIMED trial
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Stem cell-like transcriptional reprogramming mediates metastatic resistance to mTOR inhibition
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Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis
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The cannabinoid ligand LH-21 reduces anxiety and improves glucose handling in diet-induced obese pre-diabetic mice
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The Effect of Metabolic and Bariatric Surgery on DNA Methylation Patterns.
Morcillo S, Macías-González M, Tinahones FJ Current atherosclerosis reports 2017 Aug 30;19(10):40
The Impact of Body Mass Index and Nuclear beta-Catenin on Survival in Locally Advanced Rectal Cancer Treated With Preoperative Radiochemotherapy
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The pro-/anti-inflammatory effects of different fatty acids on visceral adipocytes are partially mediated by GPR120
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The role of vitamin D and VDR in carcinogenesis: Through epidemiology and basic sciences
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Unfavorable cytokine and adhesion molecule profiles during and after pregnancy, in women with gestational diabetes mellitus
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A dysregulation of glucose metabolism control is associated with carotid atherosclerosis in patients with coronary heart disease (CORDIOPREV-DIAB study)
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A Lower Olfactory Capacity Is Related to Higher Circulating Concentrations of Endocannabinoid 2-Arachidonoylglycerol and Higher Body Mass Index in Women
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A randomized clinical trial of basal insulin peglispro vs NPH in insulin-naive patients with type 2 diabetes: the IMAGINE 6 trial
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Adipose tissue glycogen accumulation is associated with obesity-linked inflammation in humans
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Adipose tissue infiltration in normal-weight subjects and its impact on metabolic function
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An Abnormal Nitric Oxide Metabolism Contributes to Brain Oxidative Stress in the Mouse Model for the Fragile X Syndrome, a Possible Role in Intellectual Disability
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An Arab registry for type 1 diabetes: global benefits for type 1 diabetes patients
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Analysis of elderly patients with diabetes participating in VIDA study on admission
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Application of the new ESPEN definition of malnutrition in geriatric diabetic patients during hospitalization: A multicentric study
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Assessment of postprandial triglycerides in clinical practice: Validation in a general population and coronary heart disease patients
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Bioavailability of tomato polyphenols is enhanced by processing and fat addition: Evidence from a randomized feeding trial
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Biomarkers of Morbid Obesity and Prediabetes by Metabolomic Profiling of Human Discordant Phenotypes
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Cardiac, renal, and neurological benefits of preoperative levosimendan administration in patients with right ventricular dysfunction and pulmonary hypertension undergoing cardiac surgery: evaluation with two biomarkers neutrophil gelatinase-associated lipocalin and neuronal enolase
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CDK4 is an essential insulin effector in adipocytes
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Clinical phenotype clustering in cardiovascular risk patients for the identification of responsive metabotypes after red wine polyphenol intake
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Commonalities in the Association between PPARG and Vitamin D Related with Obesity and Carcinogenesis
Bandera Merchan B, Tinahones FJ, Macías-González M PPAR research 2016;2016():2308249
Decision Making Impairment: A Shared Vulnerability in Obesity, Gambling Disorder and Substance Use Disorders?
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Diagnosis and treatment of iron deficiency, with or without anemia, before and after bariatric surgery
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Dietary Epicatechin Is Available to Breastfed Infants through Human Breast Milk in the Form of Host and Microbial Metabolites
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Does Metabolically Healthy Obesity Exist?
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Effect of Roux-en-Y gastric bypass-induced weight loss on the transcriptomic profiling of subcutaneous adipose tissue
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Effects of glucagon-like peptide-1 on the differentiation and metabolism of human adipocytes
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Efficacy and safety of a premixed versus a basal-plus insulin regimen as intensification for type 2 diabetes by timing of the main meal
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Efficacy and safety of switching from sitagliptin to liraglutide in subjects with type 2 diabetes (LIRA-SWITCH): a randomized, double-blind, double-dummy, active-controlled 26-week trial
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Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa
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Expert Study: Utility of an Automated Bolus Advisor System in Patients with Type 1 Diabetes Treated with Multiple Daily Injections of InsulinA Crossover Study
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Genetic Epidemiology of Glucose-6-Dehydrogenase Deficiency in the Arab World
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Genetic variations of the bitter taste receptor TAS2R38 are associated with obesity and impact on single immune traits
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Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci
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Glycemic control and maternal and fetal outcomes in pregnant women with type 1 diabetes according to the type of basal insulin
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Gut microbiota and type 2 diabetes mellitus
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Influence of Obesity and Metabolic Disease on Carotid Atherosclerosis in Patients with Coronary Artery Disease (CordioPrev Study)
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Insulin resistance is associated with specific gut microbiota in appendix samples from morbidly obese patients
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Interaction Between Orexin-A and Sleep Quality in Females in Extreme Weight Conditions
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Metabolomics-Guided Insights on Bariatric Surgery Versus Behavioral Interventions for Weight Loss
Tulipani S, Griffin J, Palau-Rodriguez M, Mora-Cubillos X, Bernal-Lopez RM, et al. Obesity (Silver Spring, Md.) 2016 Dec;24(12):2451-2466
Modulation of Irisin and Physical Activity on Executive Functions in Obesity and Morbid obesity
Fagundo AB, Jiménez-Murcia S, Giner-Bartolomé C, Agüera Z, Sauchelli S, et al. Scientific reports 2016 Aug 1;6():30820
Neonatal androgen exposure causes persistent gut microbiota dysbiosis related to metabolic disease in adult female rats.
Moreno-Indias I, Sánchez-Alcoholado L, Sánchez-Garrido MÁ, Martín-Núñez GM, Pérez-Jiménez F, et al. Endocrinology 2016 Dec;157(12):4888-4898
Normoxic Recovery Mimicking Treatment of Sleep Apnea Does Not Reverse Intermittent Hypoxia-Induced Bacterial Dysbiosis and Low-Grade Endotoxemia in Mice
Moreno-Indias I, Torres M, Sanchez-Alcoholado L, Cardona F, Almendros I, et al. Sleep 2016 Oct 1;39(10):1891-1897
Obesity Determines the Immunophenotypic Profile and Functional Characteristics of Human Mesenchymal Stem Cells From Adipose Tissue
Pachón-Peña G, Serena C, Ejarque M, Petriz J, Duran X, et al. Stem cells translational medicine 2016 Apr;5(4):464-75
Orexin and sleep quality in anorexia nervosa: Clinical relevance and influence on treatment outcome
Sauchelli S, Jiménez-Murcia S, Sánchez I, Riesco N, Custal N, et al. Psychoneuroendocrinology 2016 Mar;65():102-8
PDE5A Polymorphisms Influence on Sildenafil Treatment Success
Marchal-Escalona C, Herrera-Imbroda B, Clemente-Postigo M, Alcaide-Torres J, Quiñonero A, et al. The journal of sexual medicine 2016 Jul;13(7):1104-10
Prandial Options to Advance Basal Insulin Glargine Therapy: Testing Lixisenatide Plus Basal Insulin Versus Insulin Glulisine Either as Basal-Plus or Basal-Bolus in Type 2 Diabetes: The GetGoal Duo-2 Trial
Rosenstock J, Guerci B, Hanefeld M, Gentile S, Aronson R, et al. Diabetes care 2016 Aug;39(8):1318-28
Red wine polyphenols modulate fecal microbiota and reduce markers of the metabolic syndrome in obese patients
Moreno-Indias I, Sánchez-Alcoholado L, Pérez-Martínez P, Andrés-Lacueva C, Cardona F, et al. Food & function 2016 Apr;7(4):1775-87
RPL13A and EEF1A1 Are Suitable Reference Genes for qPCR during Adipocyte Differentiation of Vascular Stromal Cells from Patients with Different BMI and HOMA-IR
Gentile AM, Lhamyani S, Coín-Aragüez L, Oliva-Olivera W, Zayed H, et al. PloS one 2016;11(6):e0157002
Smell-taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions
Fernández-Aranda F, Agüera Z, Fernández-García JC, Garrido-Sanchez L, Alcaide-Torres J, et al. Endocrine 2016 Feb;51(2):256-67
The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice
Bermudez-Silva FJ, Romero-Zerbo SY, Haissaguerre M, Ruz-Maldonado I, Lhamyani S, et al. Disease models & mechanisms 2016 Jan;9(1):51-61
TNFA gene variants related to the inflammatory status and its association with cellular aging: From the CORDIOPREV study
Rangel-Zúñiga OA, Corina A, Lucena-Porras B, Cruz-Teno C, Gómez-Delgado F, et al. Experimental gerontology 2016 Oct;83():56-62
Trends in Bariatric Surgery in Spain in the Twenty-First Century: Baseline Results and 1-Month Follow Up of the RICIBA, a National Registry
Lecube A, de Hollanda A, Calañas A, Vilarrasa N, Rubio MA, et al. Obesity surgery 2016 Aug;26(8):1836-42
Two Healthy Diets Modulate Gut Microbial Community Improving Insulin Sensitivity in a Human Obese Population
Haro C, Montes-Borrego M, Rangel-Zúñiga OA, Alcalá-Díaz JF, Gómez-Delgado F, et al. The Journal of clinical endocrinology and metabolism 2016 Jan;101(1):233-42
Type 2 diabetes is associated with decreased PGC1 alpha expression in epicardial adipose tissue of patients with coronary artery disease
Moreno-Santos I, Pérez-Belmonte LM, Macías-González M, Mataró MJ, Castellano D, et al. Journal of translational medicine 2016 Aug 19;14(1):243
Virgin olive oil rich in phenolic compounds modulates the expression of atherosclerosis-related genes in vascular endothelium
Meza-Miranda ER, Rangel-Zúñiga OA, Marín C, Pérez-Martínez P, Delgado-Lista J, et al. European journal of nutrition 2016 Mar;55(2):519-527
Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance.
Yew Tan C, Virtue S, Murfitt S, Roberts LD, Phua YH, et al. Scientific reports 2015 Dec 17;5():18366
Advances in the treatment of prostate cancer with radiotherapy
Gómez-Millán J, Lara MF, Correa Generoso R, Perez-Rozos A, Lupiáñez-Pérez Y, et al. Critical reviews in oncology/hematology 2015 Aug;95(2):144-53
Changes in Body Composition in Anorexia Nervosa: Predictors of Recovery and Treatment Outcome
Agüera Z, Romero X, Arcelus J, Sánchez I, Riesco N, et al. PloS one 2015;10(11):e0143012
Changes in thyroid function with age: results from the Pizarra population-based longitudinal study
Lago-Sampedro AM, Gutiérrez-Repiso C, Valdés S, Maldonado C, Colomo N, et al. International journal of clinical practice 2015 May;69(5):577-87
Cilostazol Does not Improve Peripheral Arterial Disease-Linked Oxidative Stress
Bernal-Lopez MR, Peña D, Gomez-Martin P, Tinahones FJ, Gomez-Huelgas R Cardiovascular therapeutics 2015 Feb;33(1):15-9
Circulating Betatrophin Levels Are Increased in Anorexia and Decreased in Morbidly Obese Women
Barja-Fernández S, Folgueira C, Seoane LM, Casanueva FF, Dieguez C, et al. The Journal of clinical endocrinology and metabolism 2015 Sep;100(9):E1188-96
Differences in the Osteogenic Differentiation Capacity of Omental Adipose-Derived Stem Cells in Obese Patients With and Without Metabolic Syndrome.
Oliva-Olivera W, Leiva Gea A, Lhamyani S, Coín-Aragüez L, Alcaide Torres J, et al. Endocrinology 2015 Dec;156(12):4492-501
Effects of a long-term lifestyle intervention program with Mediterranean diet and exercise for the management of patients with metabolic syndrome in a primary care setting
Gomez-Huelgas R, Jansen-Chaparro S, Baca-Osorio AJ, Mancera-Romero J, Tinahones FJ, et al. European journal of internal medicine 2015 Jun;26(5):317-23
Effects of exercise on inflammation in cardiac rehabilitation
Roca-Rodríguez Mdel M, Garrido-Sánchez L, García-Almeida JM, Ruiz-Nava J, Alcaide-Torres J, et al. Nutricion hospitalaria 2015 Jun 1;31(6):2633-40
Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue
García-Fuentes E, Santiago-Fernández C, Gutiérrez-Repiso C, Mayas MD, Oliva-Olivera W, et al. Journal of translational medicine 2015 Nov 30;13():373
Impaired Adipose Tissue Expandability and Lipogenic Capacities as Ones of the Main Causes of Metabolic Disorders
Moreno-Indias I, Tinahones FJ Journal of diabetes research 2015;2015():970375
Incidence and care-related costs of severe hypoglycaemia requiring emergency treatment in Andalusia (Spain): the PAUEPAD project
Barranco RJ, Gomez-Peralta F, Abreu C, Delgado M, Palomares R, et al. Diabetic medicine : a journal of the British Diabetic Association 2015 Nov;32(11):1520-6
Increased Dihydroceramide/Ceramide Ratio Mediated by Defective Expression of degs1 Impairs Adipocyte Differentiation and Function
Barbarroja N, Rodriguez-Cuenca S, Nygren H, Camargo A, Pirraco A, et al. Diabetes 2015 Apr;64(4):1180-92
Insulin resistance determines a differential response to changes in dietary fat modification on metabolic syndrome risk factors: the LIPGENE study
Yubero-Serrano EM, Delgado-Lista J, Tierney AC, Perez-Martinez P, Garcia-Rios A, et al. The American journal of clinical nutrition 2015 Dec;102(6):1509-17
Intermittent hypoxia alters gut microbiota diversity in a mouse model of sleep apnoea
Moreno-Indias I, Torres M, Montserrat JM, Sanchez-Alcoholado L, Cardona F, et al. The European respiratory journal 2015 Apr;45(4):1055-65
Lipopolysaccharide and lipopolysaccharide-binding protein levels and their relationship to early metabolic improvement after bariatric surgery
Clemente-Postigo M, Roca-Rodriguez Mdel M, Camargo A, Ocaña-Wilhelmi L, Cardona F, et al. Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery 2015 Jul-Aug;11(4):933-9
Long-term effects of varying consumption of omega 3 fatty acids in ear, nose and throat cancer patients: assessment 1 year after radiotherapy
Roca-Rodríguez Mdel M, García-Almeida JM, Ruiz-Nava J, Alcaide J, Lupiañez-Pérez Y, et al. International journal of food sciences and nutrition 2015 Feb;66(1):108-13
Metabolomic insights into the intricate gut microbial-host interaction in the development of obesity and type 2 diabetes
Palau-Rodriguez M, Tulipani S, Isabel Queipo-Ortuño M, Urpi-Sarda M, Tinahones FJ, et al. Frontiers in microbiology 2015;6():1151
Modulation of Higher-Order Olfaction Components on Executive Functions in Humans
Fagundo AB, Jiménez-Murcia S, Giner-Bartolomé C, Islam MA, de la Torre R, et al. PloS one 2015;10(6):e0130319
Myocardial Ischemic Subject’s Thymus Fat: A Novel Source of Multipotent Stromal Cells.
Oliva-Olivera W, Coín-Aragüez L, Salas J, Lhamyani S, Gentile AM, et al. PloS one 2015;10(12):e0144401
New and Vintage Solutions To Enhance the Plasma Metabolome Coverage by LC-ESI-MS Untargeted Metabolomics: The Not-So-Simple Process of Method Performance Evaluation
Tulipani S, Mora-Cubillos X, Jáuregui O, Llorach R, García-Fuentes E, et al. Analytical chemistry 2015 Mar 3;87(5):2639-47
Newly impaired glucose metabolism and prognosis after percutaneous revascularization
Jiménez-Navarro MF, Fernández-Pastor J, Garrido-Sánchez L, Molina-Mora MJ, Ortiz-García C, et al. Cardiology journal 2015;22(1):44-51
Novel Oxazolidinone-Based Peroxisome Proliferator Activated Receptor Agonists: Molecular Modeling, Synthesis, and Biological Evaluation
Fresno N, Macías-González M, Torres-Zaguirre A, Romero-Cuevas M, Sanz-Camacho P, et al. Journal of medicinal chemistry 2015 Aug 27;58(16):6639-52
Nutrimetabolomics fingerprinting to identify biomarkers of bread exposure in a free-living population from the PREDIMED study cohort
Garcia-Aloy, M; Llorach, R; Urpi-Sarda, M; Tulipani, S; Salas-Salvado, J; Martinez-Gonzalez, MA; Corella, D; Fito, M; Estruch, R; Serra-Majem, L; Andres-Lacueva, C METABOLOMICS 2015
Obesity as a risk factor in cancer: A national consensus of the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology
Goday A, Barneto I, García-Almeida JM, Blasco A, Lecube A, et al. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2015 Oct;17(10):763-71
Olfaction in eating disorders and abnormal eating behavior: a systematic review
Islam MA, Fagundo AB, Arcelus J, Agüera Z, Jiménez-Murcia S, et al. Frontiers in psychology 2015;6():1431
Parathyroid Hormone-Related Protein, Human Adipose-Derived Stem Cells Adipogenic Capacity and Healthy Obesity
Roca-Rodríguez MM, El Bekay R, Garrido-Sanchez L, Gómez-Serrano M, Coin-Aragüez L, et al. The Journal of clinical endocrinology and metabolism 2015 Jun;100(6):E826-35
PHARMACONUTRITION IN SEVERELY ILL PATIENT
Burgos Peláez R, Escudero Álvarez E, García Almeida JM, García de Lorenzo A, García Luna PP, et al. Nutricion hospitalaria 2015 Aug 1;32(2):478-86
Phenolic and microbial-targeted metabolomics to discovering and evaluating wine intake biomarkers in human urine and plasma
Urpi-Sarda M, Boto-Ordóñez M, Queipo-Ortuño MI, Tulipani S, Corella D, et al. Electrophoresis 2015 Sep;36(18):2259-2268
Physical activity in anorexia nervosa: How relevant is it to therapy response?
Sauchelli S, Arcelus J, Sánchez I, Riesco N, Jiménez-Murcia S, et al. European psychiatry : the journal of the Association of European Psychiatrists 2015 Nov;30(8):924-31
Polymorphisms in Endothelin System Genes, Arsenic Levels and Obesity Risk
Martínez-Barquero V, de Marco G, Martínez-Hervas S, Rentero P, Galan-Chilet I, et al. PloS one 2015;10(3):e0118471
Potential advantages of volumetric arc therapy in head and neck cancer
Gomez-Millan Barrachina J, Jerez Sainz I, Perez Rozos A, Ramirez Ros JC, Toledo Serrano MD, et al. Head & neck 2015 Jun;37(6):909-14
Proteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity
Díaz-Ruiz A, Guzmán-Ruiz R, Moreno NR, García-Rios A, Delgado-Casado N, et al. Antioxidants & redox signaling 2015 Sep 1;23(7):597-612
Proteome from patients with metabolic syndrome is regulated by quantity and quality of dietary lipids
Rangel-Zúñiga OA, Camargo A, Marin C, Peña-Orihuela P, Pérez-Martínez P, et al. BMC genomics 2015 Jul 8;16():509
Sensitive and Rapid UHPLC-MS/MS for the Analysis of Tomato Phenolics in Human Biological Samples
Martínez-Huélamo M, Tulipani S, Jáuregui O, Valderas-Martinez P, Vallverdú-Queralt A, et al. Molecules (Basel, Switzerland) 2015 Nov 16;20(11):20409-25
Serum 25-Hydroxyvitamin D and Adipose Tissue Vitamin D Receptor Gene Expression: Relationship With Obesity and Type 2 Diabetes
Clemente-Postigo M, Muñoz-Garach A, Serrano M, Garrido-Sánchez L, Bernal-López MR, et al. The Journal of clinical endocrinology and metabolism 2015 Apr;100(4):E591-5
Surgery-Induced Weight Loss Is Associated With the Downregulation of Genes Targeted by MicroRNAs in Adipose Tissue
Ortega FJ, Mercader JM, Moreno-Navarrete JM, Nonell L, Puigdecanet E, et al. The Journal of clinical endocrinology and metabolism 2015 Nov;100(11):E1467-76
The effect of colostrum source (goat vs. sheep) and timing of the first colostrum feeding (2 h vs. 14 h after birth) on body weight and immune status of artificially reared newborn lambs
Hernández-Castellano LE, Morales-delaNuez A, Sánchez-Macías D, Moreno-Indias I, Torres A, et al. Journal of dairy science 2015 Jan;98(1):204-10
The effect of milk source on body weight and immune status of lambs
Hernandez-Castellano, LE; Moreno-Indias, I; Morales-delaNuez, A; Sanchez-Macias, D; Torres, A; Capote, J; Arguello, A; Castro, N LIVESTOCK SCIENCE 2015
The expression of genes involved in jejunal lipogenesis and lipoprotein synthesis is altered in morbidly obese subjects with insulin resistance
Gutierrez-Repiso C, Rodriguez-Pacheco F, Garcia-Arnes J, Valdes S, Gonzalo M, et al. Laboratory investigation; a journal of technical methods and pathology 2015 Dec;95(12):1409-17
The frequency and impact of hypoglycemia among hospitalized patients with diabetes: A population-based study.
Gómez-Huelgas R, Guijarro-Merino R, Zapatero A, Barba R, Guijarro-Contreras A, et al. Journal of diabetes and its complications 2015 Nov-Dec;29(8):1050-5
The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study
Mansego ML, De Marco G, Ivorra C, Lopez-Izquierdo R, Morcillo S, et al. Journal of translational medicine 2015 Sep 2;13():286
The tomato sauce making process affects the bioaccessibility and bioavailability of tomato phenolics: A pharmacokinetic study
Martínez-Huélamo M, Tulipani S, Estruch R, Escribano E, Illán M, et al. Food chemistry 2015 Apr 15;173():864-72
Zinc-alpha 2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase
Ceperuelo-Mallafré V, Ejarque M, Duran X, Pachón G, Vázquez-Carballo A, et al. PloS one 2015;10(6):e0129644
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