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Enfermedades Alérgicas a Fármacos y Alérgenos

Lineas de Investigación

Estudio de reacciones alérgicas

01. Estudio de los mecanismos implicados y mejora en el diagnóstico y tratamiento de las reacciones alérgicas a fármacos.

02. Estudio de los mecanismos implicados y mejora en el diagnóstico y tratamiento de las reacciones alérgicas a alimentos.

03. Estudio de los mecanismos implicados y mejora en el diagnóstico y tratamiento de la enfermedad respiratoria alérgica.

Proyecto DIFAMEM

Miembros del grupo

  • Todos
  • IR
  • Co-IR
  • Investigador
  • Otro

Proyectos de Investigación

Eguiluz Garcia, Ibon

 IP RETICs

CA18226 – New approaches for the detection of pathogens and aeroallergens

Comisión Europea
. 2019

Fernandez Duarte, Tahia

 IP RRHH

C1-0019-2019 SOLICITUD PARA EL PROGRAMA NICOLÁS MONARDES, CONVOCATORIA 2019

Servicio Andaluz de Salud (SAS)
. 2019

Gomez Perez, Francisca

 IP RRHH

B-0005-2019 ACCIONES PARA EL REFUERZO CON RECURSOS HUMANOS DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA DEL SERVICIO ANDALUZ DE SALUD 2019. ACCIÓN B CLÍNICOS INVESTIGADORES.

Servicio Andaluz de Salud (SAS)
. 2019

Salas Cassinello, Maria

 IP RRHH

A1-0015-2019 SOLICITUD PARA EL REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA (UGC) DEL SERVICIO ANDALUZ DE SALUD (SAS)

Servicio Andaluz de Salud (SAS)
. 2019

Bogas Herrera, Gador

 IP PI

PI-0076-2019. CARACTERIZACIÓN DEL FENOTIPO-ENDOTIPO E IDENTIFICACIÓN DE BIOMARCADORES EN REACCIONES DE HIPERSENSIBILIDAD A QUIMIOTERÁPICOS (SALES DE PLATINO Y TAXANOS)

Consejería de Salud y Familias
. 2019

Torres Jaen, Maria Jose

 IP PI

AC19/00082 DrNanoDAll – Nanodiagnosis for Betalactam Hypersensitivity

ISCIII
. 2019

Doña Díaz, Inmaculada

 IP PI

SEAIC 18B02. “Hipersensibilidad cruzada a ibuprofeno y otros derivados arilpropiónicos: entidades clínicas y mecanismos. Atopia e interacción fenotipo-genotipo”.

SOCIEDAD ESPAÑOLA DE ALERGOLOGÍA E INMUNOLOGÍA CLÍNICA
Sociedad Española de Alergología e Inmunología Clínica 2019

Perez Sanchez, Natalia Isabel

 IP RRHH

EF-0162-2018. Endofenotipos graves de enfermedades alérgicas respiratorias

CONSEJERÍA DE SALUD
ESTANCIAS FORMATIVAS DE INVESTIGACIÓN E INNOVACIÓN 2018

Perez Sanchez, Natalia Isabel

 IP RRHH

CM17/00141 Rio Hortega

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA 2017

Montañez Vega, María Isabel

 IP RRHH

MS15/00103 Contrato Miguel Servet Tipo I

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2015

Montañez Vega, María Isabel

 IP PI

PI17/01237 Aplicación de nanoarquitecturas sintéticas al estudio de los mecanismos de activación del basófilo y al diagnóstico en reacciones alérgicas a amoxicilina.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

Montañez Vega, María Isabel

 IP PI

CP15/00103 Development of antibiotic conjugates with nanostructures or proteins and their application to the in vitro diagnosis of antibiotic allergy

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2015

Doña Díaz, Inmaculada

 IP RRHH

B-0001-2017_Acción B Clínicos investigadores

SERVICIO ANDALUZ DE SALUD
ACCIÓN B - CLÍNICOS INVESTIGADORES. REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UGC DEL SAS 2017

Doña Díaz, Inmaculada

 IP RRHH

JR15/00036 Contrato Juan Rodés

INSTITUTO DE SALUD CARLOS III
CONTRATOS JUAN RODES 2015

Doña Díaz, Inmaculada

 IP PI

SEAIC-002-2016 Hipersensibilidad a antiinflamatorios no esteroideos: caracterización de nuevos fenotipos, papel de la atopia y análisis de la historia natural

SOCIEDAD ESPAÑOLA DE ALERGOLOGÍA E INMUNOLOGÍA CLINICA
AYUDAS PARA TRABAJOS DE INVESTIGACIÓN SEAIC 2016

Doña Díaz, Inmaculada

 IP

Cornejo García, José Antonio

 IP PI

PI17/01593 Hipersensibilidad a anti-inflamatorios no esteroideos por intolerancia cruzada: definición precisa de fenotipos, historia natural y mecanismos implicados.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

Fernandez Duarte, Tahia

 IP RRHH

RYC-2013-13138 Ramón y Cajal Tahía Diana Fernández Duarte. Se presenta por el área científica de Biomedicina

MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS RAMÓN Y CAJAL 2014

Fernandez Duarte, Tahia

 IP PI

PI-0241-2016 Desarrollo de Métodos In Vitro para el Diagnóstico de Alergia Al Ácido Clavulánico: Identificación de Los Determinantes Antigénicos Implicados en la Respuesta Inmunológica

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2016

Jurado Escobar, Raquel

 IP RRHH

FI18-00133 Contrato PFIS 2018 Raquel Jurado Escobar. Jefe de Grupo: José Antonio Cornejo García

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS PFIS: CONTRATOS PREDOCTORALES DE FORMACIÓN EN INVESTIGACIÓN EN SALUD 2018

Torres Jaen, Maria Jose

 IP RRHH

RB-0001-2018 Estudio de mecanismos inmunológicos y búsqueda de biomarcadores en hipersensibilidad a fármacos, alergia respiratoria y alergia a alimentos. UGC Alergología del HRUM

SERVICIO ANDALUZ DE SALUD
RENOVACIÓN DE LA ACCIÓN B (REFUERZOS DE LARGA DURACIÓN) DE LA CONVOCATORIA 2018

Torres Jaen, Maria Jose

 IP RRHH

INT18/00006 AllerScreening. Point of care device based on KETs for diagnosis of food allergies

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS JOSÉ MARÍA SEGOVIA DE ARANA 2018

Torres Jaen, Maria Jose

 IP RETIC

RD16/0006/0001 Asma, Reacciones Adversas y Alérgicas – ARADYAL

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS) 2016

Torres Jaen, Maria Jose

 IP PI

PE-0172-2018. Aplicación de nano-partículas y búsqueda de biomarcadores para el diagnóstico in vitro de alergia a betalactámicos.

CONSEJERÍA DE SALUD
PROYECTOS ESTRATÉGICOS DE I+D+i CON FORTALECIMIENTO DE CAPITAL HUMANO INVESTIGADOR 2018

Torres Jaen, Maria Jose

 IP PI

PI18/00095 Aproximación diagnóstica al paciente alérgico a betalactámicos mediante modelos matemáticos y pruebas in vitro. Estrategia innovadora de tratamiento basada en nano-estructuras.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

Palomares Jerez, Maria Francisca

 IP RRHH

MV18-00014 Papel de las Células Linfoides Innatas de Tipo 2 (ILC2) en el desarrollo de tolerancia inmunológica durante la inmunoterapia específica con el alérgeno

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - MOVILIDAD DE PERSONAL INVESTIGADOR CONTRATADO EN EL MARCO DE LA AES (M-AES) 2018

Palomares Jerez, Maria Francisca

 IP RRHH

CD16/00042 Contrato Sara Borrell 2016 Mª Francisca Palomares Jerez Jefe de Grupo: Cristobalina Mayorga Mayorga

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL 2016

Salas Cassinello, Maria

 IP PI

PC-0098-2017 Estudio de la Respuesta Inmunológica Humoral y de Células Efectoras Clásicas en Pacientes Con Asma Alérgico Local

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN COORDINADOS 2017

Cornejo García, José Antonio

 IP RRHH

MS14/00034 Contrato Miguel Servet Tipo I José Antonio Cornejo García

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2014

Eguiluz Garcia, Ibon

 IP RRHH

CM17/00140 Rio Hortega 2017 Ibon Eguiluz Gracia.Jefe de grupo: Cristobalina Mayorga Mayorga

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA 2017

Eguiluz Garcia, Ibon

 IP PI

PI-0176-2018. Identificación multidimensional de biomarcadores diagnósticos, pronósticos y de respuesta a corticoides en pacientes con enfermedad alérgica respiratoria

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

Bogas Herrera, Gador

 IP RRHH

JR18-00054 Contrato Juan Rodés 2018 GADOR BOGAS HERRERA

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS JUAN RODÉS 2018

Gomez Perez, Francisca

 IP RRHH

JR15/00034 Contrato Juan Rodes Francisca Gómez Pérez

INSTITUTO DE SALUD CARLOS III
CONTRATOS JUAN RODES 2015

Gomez Perez, Francisca

 IP PI

PI17/01318 Identificación de biomarcadores de utilidad diagnóstica en pacientes con alergia a LTP de fenotipo grave. Mecanismos implicados en la eficacia de la inmunoterapia con LTP

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

Mayorga Mayorga, Cristobalina

 IP RRHH

RC-0004-2016 Accion C Nicolas Monardes Cristobalina Mayorga

SERVICIO ANDALUZ DE SALUD
RENOVACIÓN ACCIÓN C (PROGRAMA NICOLÁS MONARDES) DE LA CONVOCATORIA 2016

Mayorga Mayorga, Cristobalina

 IP PI

PE-0039-2018. Intervención con prebióticos para el tratamiento de alergia a alimentos

CONSEJERÍA DE SALUD
PROYECTOS ESTRATÉGICOS DE I+D+i CON FORTALECIMIENTO DE CAPITAL HUMANO INVESTIGADOR 2018

Mayorga Mayorga, Cristobalina

 IP PI

PI18-00288 Biomarcadores inmunológicos y epigenéticos de tolerancia a alérgenos alimentarios inducida por inmunoterapia basada en nanoestructuras oligodendriméricas y epítopos T

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

Rondon Segovia, Carmen

 IP PI

PI17/01410 Estudio clínico e inmunológico de la vía aérea inferior y de la respuesta a la inmunoterapia con alérgeno en pacientes con rinitis alérgica local

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

Ariza Veguillas, Adriana

 IP RRHH

CD17/00146 Sara Borrell 2017 Adriana Ariza Veguillas.Jefe de Grupo Carmen Rondon Segovia

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL 2017

Estudios Clínicos

Gomez Perez, Francisca IP

CQGE031C2302.

Estudio multicéntrico, aleatorizado, doble ciego, con control activo y placebo para investigar la eficacia y seguridad de ligelizumab (QGE031) en el tratamiento de la urticaria crónica espontánea (UCE) en adolescentes y adultos inadecuadamente controlados

NOVARTIS FARMACEUTICA, S.A.
Fase: III ENSAYO CLINICO COMERCIAL
Torres Jaen, Maria Jose IP

CQGE031C2201E1.

Estudio de extensión, multicéntrico, abierto para evaluar la seguridad a largo plazo de QGE031 240 mg s.c. administrado cada 4 semanas durante 52 semanas en pacientes con urticaria espontánea crónica que hayan completado el estudio CQGE031C2201

NOVARTIS FARMACEUTICA, S.A.
Fase: II ENSAYO CLINICO COMERCIAL
Torres Jaen, Maria Jose IP

AL1402ac.

Estudio multicéntrico, aleatorio, doble ciego adaptativo, controlado con placebo para la evaluación de la eficacia y la seguridad de inmunoterapia especifica con una preparación alergoide de ácaros de polvo doméstico (Dermatophagoides Pteronyssinus) adher

ALLERGOPHARMA GMBH & CO. KG
Fase: III ENSAYO CLINICO COMERCIAL
Torres Jaen, Maria Jose IP

AL-X-01.

Seguridad y tolerabilidad de una pauta acortada de tratamiento con Alutard SQ

ALK-ABELLO A/S
Fase: II ENSAYO CLINICO COMERCIAL

Patentes y Tecnologías

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro
  1. Torres, MJ, Celik, GE, Whitaker, P, Atanaskovic-Markovic, M, Barbaud, A, Bircher, A et al.. A EAACI drug allergy interest group survey on how European allergy specialists deal with β-lactam allergy. Allergy. 2019;74 (6):1052-1062. doi: 10.1111/all.13721. PubMed PMID:30637768 .
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  1. Lacombe-Barrios, J, Gómez, F, Pérez, N, Barrionuevo, E, Doña, I, Fernández Tahía, D et al.. Accuracy of the Diagnosis of Allergic Reactions in the Emergency Department. J Investig Allergol Clin Immunol. 2019;29 (3):222-230. doi: 10.18176/jiaci.0313. PubMed PMID:30183657 .
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  1. Doña, I, Romano, A, Torres, MJ. Algorithm for betalactam allergy diagnosis. Allergy. 2019;74 (9):1817-1819. doi: 10.1111/all.13844. PubMed PMID:31034613 .
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  1. Mayorga, C, Montañez, MI, Jurado-Escobar, R, Gil-Ocaña, V, Cornejo-García, JA. An Update on the Immunological, Metabolic and Genetic Mechanisms in Drug Hypersensitivity Reactions. Curr Pharm Des. 2019;25 (36):3813-3828. doi: 10.2174/1381612825666191105122414. PubMed PMID:31692430 .
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  1. Campo, P, Eguiluz-Gracia, I, Plaza-Serón, MC, Salas, M, José Rodríguez, M, Pérez-Sánchez, N et al.. Bronchial asthma triggered by house dust mites in patients with local allergic rhinitis. Allergy. 2019;74 (8):1502-1510. doi: 10.1111/all.13775. PubMed PMID:30887534 .
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  1. Roth-Walter, F, Adcock, IM, Benito-Villalvilla, C, Bianchini, R, Bjermer, L, Caramori, G et al.. Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper. Allergy. 2019;74 (3):432-448. doi: 10.1111/all.13642. PubMed PMID:30353939 .
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  1. Torres, MJ, Adkinson, NF Jr, Caubet, JC, Khan, DA, Kidon, MI, Mendelson, L et al.. Controversies in Drug Allergy: Beta-Lactam Hypersensitivity Testing. J Allergy Clin Immunol Pract. 2019;7 (1):40-45. doi: 10.1016/j.jaip.2018.07.051. PubMed PMID:30245291 .
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  1. Kowalski, ML, Agache, I, Bavbek, S, Bakirtas, A, Blanca, M, Bochenek, G et al.. Diagnosis and management of NSAID-Exacerbated Respiratory Disease (N-ERD)-a EAACI position paper. Allergy. 2019;74 (1):28-39. doi: 10.1111/all.13599. PubMed PMID:30216468 .
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  1. Brockow, K, Ardern-Jones, MR, Mockenhaupt, M, Aberer, W, Barbaud, A, Caubet, JC et al.. EAACI position paper on how to classify cutaneous manifestations of drug hypersensitivity. Allergy. 2019;74 (1):14-27. doi: 10.1111/all.13562. PubMed PMID:30028512 .
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  1. Ariza, A, Torres, MJ, Moreno-Aguilar, C, Fernández-Santamaría, R, Fernández, TD. Early Biomarkers for Severe Drug Hypersensitivity Reactions. Curr Pharm Des. 2019;25 (36):3829-3839. doi: 10.2174/1381612825666191107105440. PubMed PMID:31696802 .
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  1. Doña, I, Jurado-Escobar, R, Perkins, JR, Ayuso, P, Plaza-Serón, MC, Pérez-Sánchez, N et al.. Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria. Allergy. 2019;74 (6):1135-1144. doi: 10.1111/all.13725. PubMed PMID:30667070 .
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  1. Fernandez-Santamaría, R, Palomares, F, Salas, M, Doña, I, Bogas, G, Ariza, A et al.. Expression of the Tim3-galectin-9 axis is altered in drug-induced maculopapular exanthema. Allergy. 2019;74 (9):1769-1779. doi: 10.1111/all.13847. PubMed PMID:31034608 .
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  1. Breiteneder, H, Diamant, Z, Eiwegger, T, Fokkens, WJ, Traidl-Hoffmann, C, Nadeau, K et al.. Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care. Allergy. 2019;74 (12):2293-2311. doi: 10.1111/all.13851. PubMed PMID:31056763 PubMed Central PMC6973012.
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  1. Rodriguez, MJ, Ramos-Soriano, J, Perkins, JR, Mascaraque, A, Torres, MJ, Gomez, F et al.. Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model. Sci Rep. 2019;9 (1):4043. doi: 10.1038/s41598-019-40114-7. PubMed PMID:30858392 PubMed Central PMC6411722.
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  1. Eguiluz-Gracia, I, Pérez-Sánchez, N, Bogas, G, Campo, P, Rondón, C. How to Diagnose and Treat Local Allergic Rhinitis: A Challenge for Clinicians. J Clin Med. 2019;8 (7):. doi: 10.3390/jcm8071062. PubMed PMID:31331047 PubMed Central PMC6678883.
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  1. Eiwegger, T, Anagnostou, K, Arasi, S, Bégin, P, Ben-Shoshan, M, Beyer, K et al.. ICER report for peanut OIT comes up short. Ann Allergy Asthma Immunol. 2019;123 (5):430-432. doi: 10.1016/j.anai.2019.09.001. PubMed PMID:31513908 .
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  1. Barbero, N, Fernández-Santamaría, R, Mayorga, C, Martin-Serrano, Á, Salas, M, Bogas, G et al.. Identification of an antigenic determinant of clavulanic acid responsible for IgE-mediated reactions. Allergy. 2019;74 (8):1490-1501. doi: 10.1111/all.13761. PubMed PMID:30829415 .
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  1. Amo, G, Martí, M, García-Menaya, JM, Cordobés, C, Cornejo-García, JA, Blanca-López, N et al.. Identification of Novel Biomarkers for Drug Hypersensitivity After Sequencing of the Promoter Area in 16 Genes of the Vitamin D Pathway and the High-Affinity IgE Receptor. Front Genet. 2019;10 :582. doi: 10.3389/fgene.2019.00582. PubMed PMID:31293618 PubMed Central PMC6603231.
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  1. Campo, P, Eguiluz-Gracia, I, Bogas, G, Salas, M, Plaza Serón, C, Pérez, N et al.. Local allergic rhinitis: Implications for management. Clin Exp Allergy. 2019;49 (1):6-16. doi: 10.1111/cea.13192. PubMed PMID:29900607 .
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  1. Leonardi, A, Silva, D, Perez Formigo, D, Bozkurt, B, Sharma, V, Allegri, P et al.. Management of ocular allergy. Allergy. 2019;74 (9):1611-1630. doi: 10.1111/all.13786. PubMed PMID:30887530 .
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  1. Eguiluz-Gracia, I, Layhadi, JA, Rondon, C, Shamji, MH. Mucosal IgE immune responses in respiratory diseases. Curr Opin Pharmacol. 2019;46 :100-107. doi: 10.1016/j.coph.2019.05.009. PubMed PMID:31220711 .
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  1. Perkins, JR, Acosta-Herrera, M, Plaza-Serón, MC, Jurado-Escobar, R, Doña, I, García-Martín, E et al.. Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs. Pharmacogenomics J. 2019;19 (2):191-199. doi: 10.1038/s41397-018-0038-0. PubMed PMID:30093714 .
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  1. Agache, I, Annesi-Maesano, I, Bonertz, A, Branca, F, Cant, A, Fras, Z et al.. Prioritizing research challenges and funding for allergy and asthma and the need for translational research-The European Strategic Forum on Allergic Diseases. Allergy. 2019;74 (11):2064-2076. doi: 10.1111/all.13856. PubMed PMID:31070805 .
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  1. Palomares, F, Ramos-Soriano, J, Gomez, F, Mascaraque, A, Bogas, G, Perkins, JR et al.. Pru p 3-Glycodendropeptides Based on Mannoses Promote Changes in the Immunological Properties of Dendritic and T-Cells from LTP-Allergic Patients. Mol Nutr Food Res. 2019;63 (20):e1900553. doi: 10.1002/mnfr.201900553. PubMed PMID:31368251 .
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  1. Alba-Linero, C, Rocha De Lossada, C, Delgado-Fernández, AS, Jódar-Márquez, M, Rodríguez Calvo De Mora, M, Berciano-Guerrero, MA et al.. Pseudovitelliform maculopathy secondary to BRAF and MEK inhibitors in a patient with metastasic melanoma. J Biol Regul Homeost Agents. ;33 (5):1497-1500. doi: 10.23812/19-89-L. PubMed PMID:31583878 .
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  1. Gastaminza, G, Ruiz-Canela, M, Andrés-López, B, Barasona Villarejo, MJ, Cabañas, R, García-Núñez, I et al.. Quality of Life in Patients with Allergic Reactions to Medications: Influence of a Drug Allergy Evaluation. J Allergy Clin Immunol Pract. ;7 (8):2714-2721. doi: 10.1016/j.jaip.2019.05.017. PubMed PMID:31129076 .
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  1. Mayorga, C, Fernandez, TD, Montañez, MI, Moreno, E, Torres, MJ. Recent developments and highlights in drug hypersensitivity. Allergy. 2019;74 (12):2368-2381. doi: 10.1111/all.14061. PubMed PMID:31557314 .
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  1. Layhadi, JA, Eguiluz-Gracia, I, Shamji, MH. Role of IL-35 in sublingual allergen immunotherapy. Curr Opin Allergy Clin Immunol. 2019;19 (1):12-17. doi: 10.1097/ACI.0000000000000499. PubMed PMID:30507716 .
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  1. Eguiluz-Gracia, I, Testera-Montes, A, González, M, Pérez-Sánchez, N, Ariza, A, Salas, M et al.. Safety and reproducibility of nasal allergen challenge. Allergy. 2019;74 (6):1125-1134. doi: 10.1111/all.13728. PubMed PMID:30667530 .
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  1. Campo, P, Soto Campos, G, Aparicio, MB, Jorge, AM, González Expósito, HM, Quirce, S et al.. Severe asthma phenotypes in patients controlled with omalizumab: A real-world study. Respir Med. 2019;159 :105804. doi: 10.1016/j.rmed.2019.105804. PubMed PMID:31704593 .
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  1. Rodriguez, MJ, Palomares, F, Bogas, G, Torres, MJ, Diaz-Perales, A, Rojo, J et al.. Transcriptional Profiling of Dendritic Cells in a Mouse Model of Food-Antigen-Induced Anaphylaxis Reveals the Upregulation of Multiple Immune-Related Pathways. Mol Nutr Food Res. 2019;63 (3):e1800759. doi: 10.1002/mnfr.201800759. PubMed PMID:30458065 .
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  1. Oeo-Santos, C, Mas, S, Benedé, S, López-Lucendo, M, Quiralte, J, Blanca, M et al.. A recombinant isoform of the Ole e 7 olive pollen allergen assembled by de novo mass spectrometry retains the allergenic ability of the natural allergen. J Proteomics. 2018;187 :39-46. doi: 10.1016/j.jprot.2018.06.001. PubMed PMID:29883846 .
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  1. Doña, I, Caubet, JC, Brockow, K, Doyle, M, Moreno, E, Terreehorst, I et al.. An EAACI task force report: recognising the potential of the primary care physician in the diagnosis and management of drug hypersensitivity. Clin Transl Allergy. 2018;8 :16. doi: 10.1186/s13601-018-0202-2. PubMed PMID:29760877 PubMed Central PMC5944153.
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  1. García-Martín, E, Sánchez-Gómez, FJ, Amo, G, García Menaya, J, Cordobés, C, Ayuso, P et al.. Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels. Hum Mutat. 2018;39 (8):1081-1091. doi: 10.1002/humu.23548. PubMed PMID:29726087 .
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  1. Molina, N, Martin-Serrano, A, Fernandez, TD, Tesfaye, A, Najera, F, Torres, MJ et al.. Dendrimeric Antigens for Drug Allergy Diagnosis: A New Approach for Basophil Activation Tests. Molecules. 2018;23 (5):. doi: 10.3390/molecules23050997. PubMed PMID:29695102 PubMed Central PMC6100007.
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