Lineas de Investigación

Estudio de reacciones alérgicas

01. Estudio de los mecanismos implicados y mejora en el diagnóstico y tratamiento de las reacciones alérgicas a fármacos.

02. Estudio de los mecanismos implicados y mejora en el diagnóstico y tratamiento de las reacciones alérgicas a alimentos.

03. Estudio de los mecanismos implicados y mejora en el diagnóstico y tratamiento de la enfermedad respiratoria alérgica.

Proyecto DIFAMEM



Proyectos de Investigación

CA18226 – New approaches for the detection of pathogens and aeroallergens

Comisión Europea
. 2019

C1-0019-2019 SOLICITUD PARA EL PROGRAMA NICOLÁS MONARDES, CONVOCATORIA 2019

Servicio Andaluz de Salud (SAS)
. 2019

B-0005-2019 ACCIONES PARA EL REFUERZO CON RECURSOS HUMANOS DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA DEL SERVICIO ANDALUZ DE SALUD 2019. ACCIÓN B CLÍNICOS INVESTIGADORES.

Servicio Andaluz de Salud (SAS)
. 2019

A1-0015-2019 SOLICITUD PARA EL REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UNIDADES DE GESTIÓN CLÍNICA (UGC) DEL SERVICIO ANDALUZ DE SALUD (SAS)

Servicio Andaluz de Salud (SAS)
. 2019

PI-0076-2019. CARACTERIZACIÓN DEL FENOTIPO-ENDOTIPO E IDENTIFICACIÓN DE BIOMARCADORES EN REACCIONES DE HIPERSENSIBILIDAD A QUIMIOTERÁPICOS (SALES DE PLATINO Y TAXANOS)

Consejería de Salud y Familias
. 2019

AC19/00082 DrNanoDAll – Nanodiagnosis for Betalactam Hypersensitivity

ISCIII
. 2019

SEAIC 18B02. “Hipersensibilidad cruzada a ibuprofeno y otros derivados arilpropiónicos: entidades clínicas y mecanismos. Atopia e interacción fenotipo-genotipo”.

SOCIEDAD ESPAÑOLA DE ALERGOLOGÍA E INMUNOLOGÍA CLÍNICA
Sociedad Española de Alergología e Inmunología Clínica 2019

EF-0162-2018. Endofenotipos graves de enfermedades alérgicas respiratorias

CONSEJERÍA DE SALUD
ESTANCIAS FORMATIVAS DE INVESTIGACIÓN E INNOVACIÓN 2018

CM17/00141 Rio Hortega

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA 2017

MS15/00103 Contrato Miguel Servet Tipo I

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2015

PI17/01237 Aplicación de nanoarquitecturas sintéticas al estudio de los mecanismos de activación del basófilo y al diagnóstico en reacciones alérgicas a amoxicilina.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

CP15/00103 Development of antibiotic conjugates with nanostructures or proteins and their application to the in vitro diagnosis of antibiotic allergy

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2015

B-0001-2017_Acción B Clínicos investigadores

SERVICIO ANDALUZ DE SALUD
ACCIÓN B - CLÍNICOS INVESTIGADORES. REFUERZO ANUAL DE LA ACTIVIDAD INVESTIGADORA EN LAS UGC DEL SAS 2017

JR15/00036 Contrato Juan Rodés

INSTITUTO DE SALUD CARLOS III
CONTRATOS JUAN RODES 2015

SEAIC-002-2016 Hipersensibilidad a antiinflamatorios no esteroideos: caracterización de nuevos fenotipos, papel de la atopia y análisis de la historia natural

SOCIEDAD ESPAÑOLA DE ALERGOLOGÍA E INMUNOLOGÍA CLINICA
AYUDAS PARA TRABAJOS DE INVESTIGACIÓN SEAIC 2016

PI17/01593 Hipersensibilidad a anti-inflamatorios no esteroideos por intolerancia cruzada: definición precisa de fenotipos, historia natural y mecanismos implicados.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

RYC-2013-13138 Ramón y Cajal Tahía Diana Fernández Duarte. Se presenta por el área científica de Biomedicina

MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS RAMÓN Y CAJAL 2014

PI-0241-2016 Desarrollo de Métodos In Vitro para el Diagnóstico de Alergia Al Ácido Clavulánico: Identificación de Los Determinantes Antigénicos Implicados en la Respuesta Inmunológica

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2016

FI18-00133 Contrato PFIS 2018 Raquel Jurado Escobar. Jefe de Grupo: José Antonio Cornejo García

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS PFIS: CONTRATOS PREDOCTORALES DE FORMACIÓN EN INVESTIGACIÓN EN SALUD 2018

RB-0001-2018 Estudio de mecanismos inmunológicos y búsqueda de biomarcadores en hipersensibilidad a fármacos, alergia respiratoria y alergia a alimentos. UGC Alergología del HRUM

SERVICIO ANDALUZ DE SALUD
RENOVACIÓN DE LA ACCIÓN B (REFUERZOS DE LARGA DURACIÓN) DE LA CONVOCATORIA 2018

INT18/00006 AllerScreening. Point of care device based on KETs for diagnosis of food allergies

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS JOSÉ MARÍA SEGOVIA DE ARANA 2018

RD16/0006/0001 Asma, Reacciones Adversas y Alérgicas – ARADYAL

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS) 2016

PE-0172-2018. Aplicación de nano-partículas y búsqueda de biomarcadores para el diagnóstico in vitro de alergia a betalactámicos.

CONSEJERÍA DE SALUD
PROYECTOS ESTRATÉGICOS DE I+D+i CON FORTALECIMIENTO DE CAPITAL HUMANO INVESTIGADOR 2018

PI18/00095 Aproximación diagnóstica al paciente alérgico a betalactámicos mediante modelos matemáticos y pruebas in vitro. Estrategia innovadora de tratamiento basada en nano-estructuras.

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

MV18-00014 Papel de las Células Linfoides Innatas de Tipo 2 (ILC2) en el desarrollo de tolerancia inmunológica durante la inmunoterapia específica con el alérgeno

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - MOVILIDAD DE PERSONAL INVESTIGADOR CONTRATADO EN EL MARCO DE LA AES (M-AES) 2018

CD16/00042 Contrato Sara Borrell 2016 Mª Francisca Palomares Jerez Jefe de Grupo: Cristobalina Mayorga Mayorga

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL 2016

PC-0098-2017 Estudio de la Respuesta Inmunológica Humoral y de Células Efectoras Clásicas en Pacientes Con Asma Alérgico Local

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN COORDINADOS 2017

MS14/00034 Contrato Miguel Servet Tipo I José Antonio Cornejo García

INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I 2014

CM17/00140 Rio Hortega 2017 Ibon Eguiluz Gracia.Jefe de grupo: Cristobalina Mayorga Mayorga

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS RÍO HORTEGA 2017

PI-0176-2018. Identificación multidimensional de biomarcadores diagnósticos, pronósticos y de respuesta a corticoides en pacientes con enfermedad alérgica respiratoria

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

JR18-00054 Contrato Juan Rodés 2018 GADOR BOGAS HERRERA

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS JUAN RODÉS 2018

JR15/00034 Contrato Juan Rodes Francisca Gómez Pérez

INSTITUTO DE SALUD CARLOS III
CONTRATOS JUAN RODES 2015

PI17/01318 Identificación de biomarcadores de utilidad diagnóstica en pacientes con alergia a LTP de fenotipo grave. Mecanismos implicados en la eficacia de la inmunoterapia con LTP

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

RC-0004-2016 Accion C Nicolas Monardes Cristobalina Mayorga

SERVICIO ANDALUZ DE SALUD
RENOVACIÓN ACCIÓN C (PROGRAMA NICOLÁS MONARDES) DE LA CONVOCATORIA 2016

PE-0039-2018. Intervención con prebióticos para el tratamiento de alergia a alimentos

CONSEJERÍA DE SALUD
PROYECTOS ESTRATÉGICOS DE I+D+i CON FORTALECIMIENTO DE CAPITAL HUMANO INVESTIGADOR 2018

PI18-00288 Biomarcadores inmunológicos y epigenéticos de tolerancia a alérgenos alimentarios inducida por inmunoterapia basada en nanoestructuras oligodendriméricas y epítopos T

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD 2018

PI17/01410 Estudio clínico e inmunológico de la vía aérea inferior y de la respuesta a la inmunoterapia con alérgeno en pacientes con rinitis alérgica local

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS) 2017

CD17/00146 Sara Borrell 2017 Adriana Ariza Veguillas.Jefe de Grupo Carmen Rondon Segovia

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL 2017

Estudios Clínicos

CQGE031C2302. Estudio multicéntrico, aleatorizado, doble ciego, con control activo y placebo para investigar la eficacia y seguridad de ligelizumab (QGE031) en el tratamiento de la urticaria crónica espontánea (UCE) en adolescentes y adultos inadecuadamente controlados

NOVARTIS FARMACEUTICA, S.A.
Fase: III ENSAYO CLINICO COMERCIAL

CQGE031C2201E1. Estudio de extensión, multicéntrico, abierto para evaluar la seguridad a largo plazo de QGE031 240 mg s.c. administrado cada 4 semanas durante 52 semanas en pacientes con urticaria espontánea crónica que hayan completado el estudio CQGE031C2201

NOVARTIS FARMACEUTICA, S.A.
Fase: II ENSAYO CLINICO COMERCIAL

AL1402ac. Estudio multicéntrico, aleatorio, doble ciego adaptativo, controlado con placebo para la evaluación de la eficacia y la seguridad de inmunoterapia especifica con una preparación alergoide de ácaros de polvo doméstico (Dermatophagoides Pteronyssinus) adher

ALLERGOPHARMA GMBH & CO. KG
Fase: III ENSAYO CLINICO COMERCIAL

AL-X-01. Seguridad y tolerabilidad de una pauta acortada de tratamiento con Alutard SQ

ALK-ABELLO A/S
Fase: II ENSAYO CLINICO COMERCIAL


Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro
  1. Torres, MJ, Celik, GE, Whitaker, P, Atanaskovic-Markovic, M, Barbaud, A, Bircher, A et al.. A EAACI drug allergy interest group survey on how European allergy specialists deal with β-lactam allergy. Allergy. 2019;74 (6):1052-1062. doi: 10.1111/all.13721. PubMed PMID:30637768 .
Search PubMed
  1. Lacombe-Barrios, J, Gómez, F, Pérez, N, Barrionuevo, E, Doña, I, Fernández Tahía, D et al.. Accuracy of the Diagnosis of Allergic Reactions in the Emergency Department. J Investig Allergol Clin Immunol. 2019;29 (3):222-230. doi: 10.18176/jiaci.0313. PubMed PMID:30183657 .
Search PubMed
  1. Doña, I, Romano, A, Torres, MJ. Algorithm for betalactam allergy diagnosis. Allergy. 2019;74 (9):1817-1819. doi: 10.1111/all.13844. PubMed PMID:31034613 .
Search PubMed
  1. Mayorga, C, Montañez, MI, Jurado-Escobar, R, Gil-Ocaña, V, Cornejo-García, JA. An Update on the Immunological, Metabolic and Genetic Mechanisms in Drug Hypersensitivity Reactions. Curr. Pharm. Des. 2019;25 (36):3813-3828. doi: 10.2174/1381612825666191105122414. PubMed PMID:31692430 .
Search PubMed
  1. Campo, P, Eguiluz-Gracia, I, Plaza-Serón, MC, Salas, M, José Rodríguez, M, Pérez-Sánchez, N et al.. Bronchial asthma triggered by house dust mites in patients with local allergic rhinitis. Allergy. 2019;74 (8):1502-1510. doi: 10.1111/all.13775. PubMed PMID:30887534 .
Search PubMed
  1. Roth-Walter, F, Adcock, IM, Benito-Villalvilla, C, Bianchini, R, Bjermer, L, Caramori, G et al.. Comparing biologicals and small molecule drug therapies for chronic respiratory diseases: An EAACI Taskforce on Immunopharmacology position paper. Allergy. 2019;74 (3):432-448. doi: 10.1111/all.13642. PubMed PMID:30353939 .
Search PubMed
  1. Torres, MJ, Adkinson, NF Jr, Caubet, JC, Khan, DA, Kidon, MI, Mendelson, L et al.. Controversies in Drug Allergy: Beta-Lactam Hypersensitivity Testing. J Allergy Clin Immunol Pract. 2019;7 (1):40-45. doi: 10.1016/j.jaip.2018.07.051. PubMed PMID:30245291 .
Search PubMed
  1. Kowalski, ML, Agache, I, Bavbek, S, Bakirtas, A, Blanca, M, Bochenek, G et al.. Diagnosis and management of NSAID-Exacerbated Respiratory Disease (N-ERD)-a EAACI position paper. Allergy. 2019;74 (1):28-39. doi: 10.1111/all.13599. PubMed PMID:30216468 .
Search PubMed
  1. Brockow, K, Ardern-Jones, MR, Mockenhaupt, M, Aberer, W, Barbaud, A, Caubet, JC et al.. EAACI position paper on how to classify cutaneous manifestations of drug hypersensitivity. Allergy. 2019;74 (1):14-27. doi: 10.1111/all.13562. PubMed PMID:30028512 .
Search PubMed
  1. Ariza, A, Torres, MJ, Moreno-Aguilar, C, Fernández-Santamaría, R, Fernández, TD. Early Biomarkers for Severe Drug Hypersensitivity Reactions. Curr. Pharm. Des. 2019;25 (36):3829-3839. doi: 10.2174/1381612825666191107105440. PubMed PMID:31696802 .
Search PubMed
  1. Doña, I, Jurado-Escobar, R, Perkins, JR, Ayuso, P, Plaza-Serón, MC, Pérez-Sánchez, N et al.. Eicosanoid mediator profiles in different phenotypes of nonsteroidal anti-inflammatory drug-induced urticaria. Allergy. 2019;74 (6):1135-1144. doi: 10.1111/all.13725. PubMed PMID:30667070 .
Search PubMed
  1. Fernandez-Santamaría, R, Palomares, F, Salas, M, Doña, I, Bogas, G, Ariza, A et al.. Expression of the Tim3-galectin-9 axis is altered in drug-induced maculopapular exanthema. Allergy. 2019;74 (9):1769-1779. doi: 10.1111/all.13847. PubMed PMID:31034608 .
Search PubMed
  1. Breiteneder, H, Diamant, Z, Eiwegger, T, Fokkens, WJ, Traidl-Hoffmann, C, Nadeau, K et al.. Future research trends in understanding the mechanisms underlying allergic diseases for improved patient care. Allergy. 2019;74 (12):2293-2311. doi: 10.1111/all.13851. PubMed PMID:31056763 PubMed Central PMC6973012.
Search PubMed
  1. Rodriguez, MJ, Ramos-Soriano, J, Perkins, JR, Mascaraque, A, Torres, MJ, Gomez, F et al.. Glycosylated nanostructures in sublingual immunotherapy induce long-lasting tolerance in LTP allergy mouse model. Sci Rep. 2019;9 (1):4043. doi: 10.1038/s41598-019-40114-7. PubMed PMID:30858392 PubMed Central PMC6411722.
Search PubMed
  1. Eguiluz-Gracia, I, Pérez-Sánchez, N, Bogas, G, Campo, P, Rondón, C. How to Diagnose and Treat Local Allergic Rhinitis: A Challenge for Clinicians. J Clin Med. 2019;8 (7):. doi: 10.3390/jcm8071062. PubMed PMID:31331047 PubMed Central PMC6678883.
Search PubMed
  1. Eiwegger, T, Anagnostou, K, Arasi, S, Bégin, P, Ben-Shoshan, M, Beyer, K et al.. ICER report for peanut OIT comes up short. Ann. Allergy Asthma Immunol. 2019;123 (5):430-432. doi: 10.1016/j.anai.2019.09.001. PubMed PMID:31513908 .
Search PubMed
  1. Barbero, N, Fernández-Santamaría, R, Mayorga, C, Martin-Serrano, Á, Salas, M, Bogas, G et al.. Identification of an antigenic determinant of clavulanic acid responsible for IgE-mediated reactions. Allergy. 2019;74 (8):1490-1501. doi: 10.1111/all.13761. PubMed PMID:30829415 .
Search PubMed
  1. Amo, G, Martí, M, García-Menaya, JM, Cordobés, C, Cornejo-García, JA, Blanca-López, N et al.. Identification of Novel Biomarkers for Drug Hypersensitivity After Sequencing of the Promoter Area in 16 Genes of the Vitamin D Pathway and the High-Affinity IgE Receptor. Front Genet. 2019;10 :582. doi: 10.3389/fgene.2019.00582. PubMed PMID:31293618 PubMed Central PMC6603231.
Search PubMed
  1. Campo, P, Eguiluz-Gracia, I, Bogas, G, Salas, M, Plaza Serón, C, Pérez, N et al.. Local allergic rhinitis: Implications for management. Clin. Exp. Allergy. 2019;49 (1):6-16. doi: 10.1111/cea.13192. PubMed PMID:29900607 .
Search PubMed
  1. Leonardi, A, Silva, D, Perez Formigo, D, Bozkurt, B, Sharma, V, Allegri, P et al.. Management of ocular allergy. Allergy. 2019;74 (9):1611-1630. doi: 10.1111/all.13786. PubMed PMID:30887530 .
Search PubMed
  1. Eguiluz-Gracia, I, Layhadi, JA, Rondon, C, Shamji, MH. Mucosal IgE immune responses in respiratory diseases. Curr Opin Pharmacol. 2019;46 :100-107. doi: 10.1016/j.coph.2019.05.009. PubMed PMID:31220711 .
Search PubMed
  1. Perkins, JR, Acosta-Herrera, M, Plaza-Serón, MC, Jurado-Escobar, R, Doña, I, García-Martín, E et al.. Polymorphisms in CEP68 gene associated with risk of immediate selective reactions to non-steroidal anti-inflammatory drugs. Pharmacogenomics J. 2019;19 (2):191-199. doi: 10.1038/s41397-018-0038-0. PubMed PMID:30093714 .
Search PubMed
  1. Agache, I, Annesi-Maesano, I, Bonertz, A, Branca, F, Cant, A, Fras, Z et al.. Prioritizing research challenges and funding for allergy and asthma and the need for translational research-The European Strategic Forum on Allergic Diseases. Allergy. 2019;74 (11):2064-2076. doi: 10.1111/all.13856. PubMed PMID:31070805 .
Search PubMed
  1. Palomares, F, Ramos-Soriano, J, Gomez, F, Mascaraque, A, Bogas, G, Perkins, JR et al.. Pru p 3-Glycodendropeptides Based on Mannoses Promote Changes in the Immunological Properties of Dendritic and T-Cells from LTP-Allergic Patients. Mol Nutr Food Res. 2019;63 (20):e1900553. doi: 10.1002/mnfr.201900553. PubMed PMID:31368251 .
Search PubMed
  1. Alba-Linero, C, Rocha De Lossada, C, Delgado-Fernández, AS, Jódar-Márquez, M, Rodríguez Calvo De Mora, M, Berciano-Guerrero, MA et al.. Pseudovitelliform maculopathy secondary to BRAF and MEK inhibitors in a patient with metastasic melanoma. J. Biol. Regul. Homeost. Agents. ;33 (5):1497-1500. doi: 10.23812/19-89-L. PubMed PMID:31583878 .
Search PubMed
  1. Gastaminza, G, Ruiz-Canela, M, Andrés-López, B, Barasona Villarejo, MJ, Cabañas, R, García-Núñez, I et al.. Quality of Life in Patients with Allergic Reactions to Medications: Influence of a Drug Allergy Evaluation. J Allergy Clin Immunol Pract. ;7 (8):2714-2721. doi: 10.1016/j.jaip.2019.05.017. PubMed PMID:31129076 .
Search PubMed
  1. Mayorga, C, Fernandez, TD, Montañez, MI, Moreno, E, Torres, MJ. Recent developments and highlights in drug hypersensitivity. Allergy. 2019;74 (12):2368-2381. doi: 10.1111/all.14061. PubMed PMID:31557314 .
Search PubMed
  1. Layhadi, JA, Eguiluz-Gracia, I, Shamji, MH. Role of IL-35 in sublingual allergen immunotherapy. Curr Opin Allergy Clin Immunol. 2019;19 (1):12-17. doi: 10.1097/ACI.0000000000000499. PubMed PMID:30507716 .
Search PubMed
  1. Eguiluz-Gracia, I, Testera-Montes, A, González, M, Pérez-Sánchez, N, Ariza, A, Salas, M et al.. Safety and reproducibility of nasal allergen challenge. Allergy. 2019;74 (6):1125-1134. doi: 10.1111/all.13728. PubMed PMID:30667530 .
Search PubMed
  1. Campo, P, Soto Campos, G, Aparicio, MB, Jorge, AM, González Expósito, HM, Quirce, S et al.. Severe asthma phenotypes in patients controlled with omalizumab: A real-world study. Respir Med. 2019;159 :105804. doi: 10.1016/j.rmed.2019.105804. PubMed PMID:31704593 .
Search PubMed
  1. Rodriguez, MJ, Palomares, F, Bogas, G, Torres, MJ, Diaz-Perales, A, Rojo, J et al.. Transcriptional Profiling of Dendritic Cells in a Mouse Model of Food-Antigen-Induced Anaphylaxis Reveals the Upregulation of Multiple Immune-Related Pathways. Mol Nutr Food Res. 2019;63 (3):e1800759. doi: 10.1002/mnfr.201800759. PubMed PMID:30458065 .
Search PubMed
  1. Oeo-Santos, C, Mas, S, Benedé, S, López-Lucendo, M, Quiralte, J, Blanca, M et al.. A recombinant isoform of the Ole e 7 olive pollen allergen assembled by de novo mass spectrometry retains the allergenic ability of the natural allergen. J Proteomics. 2018;187 :39-46. doi: 10.1016/j.jprot.2018.06.001. PubMed PMID:29883846 .
Search PubMed
  1. Doña, I, Caubet, JC, Brockow, K, Doyle, M, Moreno, E, Terreehorst, I et al.. An EAACI task force report: recognising the potential of the primary care physician in the diagnosis and management of drug hypersensitivity. Clin Transl Allergy. 2018;8 :16. doi: 10.1186/s13601-018-0202-2. PubMed PMID:29760877 PubMed Central PMC5944153.
Search PubMed
  1. García-Martín, E, Sánchez-Gómez, FJ, Amo, G, García Menaya, J, Cordobés, C, Ayuso, P et al.. Asthma and allergic rhinitis associate with the rs2229542 variant that induces a p.Lys90Glu mutation and compromises AKR1B1 protein levels. Hum. Mutat. 2018;39 (8):1081-1091. doi: 10.1002/humu.23548. PubMed PMID:29726087 .
Search PubMed
  1. Molina, N, Martin-Serrano, A, Fernandez, TD, Tesfaye, A, Najera, F, Torres, MJ et al.. Dendrimeric Antigens for Drug Allergy Diagnosis: A New Approach for Basophil Activation Tests. Molecules. 2018;23 (5):. doi: 10.3390/molecules23050997. PubMed PMID:29695102 PubMed Central PMC6100007.
Search PubMed
  1. Lu, Q, Huang, T, Zhou, J, Zeng, Y, Wu, C, Liu, M et al.. Limitation-induced fluorescence enhancement of carbon nanoparticles and their application for glucose detection. Spectrochim Acta A Mol Biomol Spectrosc. 2020;244 :118893. doi: 10.1016/j.saa.2020.118893. PubMed PMID:32916589 .
  2. Cusano, AM, Aliberti, A, Cusano, A, Ruvo, M. Detection of small DNA fragments by biolayer interferometry. Anal. Biochem. 2020;607 :113898. doi: 10.1016/j.ab.2020.113898. PubMed PMID:32777266 .
  3. Chen, J, Feng, S, Chen, M, Li, P, Yang, Y, Zhang, J et al.. In Vivo Dynamic Monitoring of Bacterial Infection by NIR-II Fluorescence Imaging. Small. 2020;16 (34):e2002054. doi: 10.1002/smll.202002054. PubMed PMID:32715565 .
  4. Ierardi, AM, Pavilonis, B. Heat stress risk among New York City public school kitchen workers: a quantitative exposure assessment. J Occup Environ Hyg. ;17 (7-8):353-363. doi: 10.1080/15459624.2020.1776300. PubMed PMID:32552608 .
  5. Blitstein, JL, Guthrie, JF, Rains, C. Low-Income Parents' Use of Front-of-Package Nutrition Labels in a Virtual Supermarket. J Nutr Educ Behav. 2020;52 (9):850-858. doi: 10.1016/j.jneb.2020.04.003. PubMed PMID:32475704 .
  6. Zhang, K, Sun, D, Duan, C, Chen, H, Din, AU, Kong, X et al.. Application of a Faecalibacterium 16S rDNA genetic marker for species identification of dog fecal waste. Environ Sci Pollut Res Int. 2020;27 (24):30615-30624. doi: 10.1007/s11356-020-09369-w. PubMed PMID:32472511 .
  7. Bharali, B, Talukdar, H, Phukan, P, Das, DK. A New Schiff Base Based Fluorescent Sensor for Al(III) Based on 2-Hydroxyacetophenone and o-Phenylenediamine. J Fluoresc. 2020;30 (4):751-757. doi: 10.1007/s10895-020-02527-w. PubMed PMID:32410084 .
  8. Vujacic-Mirski, K, Bruns, K, Kalinovic, S, Oelze, M, Kröller-Schön, S, Steven, S et al.. Development of an Analytical Assay for Electrochemical Detection and Quantification of Protein-Bound 3-Nitrotyrosine in Biological Samples and Comparison with Classical, Antibody-Based Methods. Antioxidants (Basel). 2020;9 (5):. doi: 10.3390/antiox9050388. PubMed PMID:32384768 PubMed Central PMC7278855.
  9. Planelló, R, Herrero, O, García, P, Beltrán, EM, Llorente, L, Sánchez-Argüello, P et al.. Developmental/reproductive effects and gene expression variations in Chironomus riparius after exposure to reclaimed water and its fortification with carbamazepine and triclosan. Water Res. 2020;178 :115790. doi: 10.1016/j.watres.2020.115790. PubMed PMID:32334179 .
  10. Liu, Y, Zhao, C, Zhao, W, Zhang, H, Yao, S, Shi, Y et al.. Multi-functional MnO2-doped Fe3O4 nanoparticles as an artificial enzyme for the colorimetric detection of bacteria. Anal Bioanal Chem. 2020;412 (13):3135-3140. doi: 10.1007/s00216-020-02563-2. PubMed PMID:32285182 .
  11. Casucci, C, De Bernardi, A, D'Amato, R, Businelli, D, Vischetti, C. Zeolite and bentonite as nickel sequestrants in carbonation lime coming from the sugar industry. Environ Sci Pollut Res Int. 2020;27 (15):18803-18809. doi: 10.1007/s11356-020-08469-x. PubMed PMID:32207012 .
  12. Liu, Q, Huang, C, Chris Le, X. Arsenic species in electronic cigarettes: Determination and potential health risk. J Environ Sci (China). 2020;91 :168-176. doi: 10.1016/j.jes.2020.01.023. PubMed PMID:32172965 .
  13. Jiang, Y, Xiao, X, Li, C, Luo, Y, Chen, S, Shi, G et al.. Facile Ratiometric Electrochemical Sensor for In Vivo/Online Repetitive Measurements of Cerebral Ascorbic Acid in Brain Microdiaysate. Anal. Chem. 2020;92 (5):3981-3989. doi: 10.1021/acs.analchem.9b05484. PubMed PMID:32037799 .
  14. Miranda, KWE, Natarelli, CVL, Thomazi, AC, Ferreira, GMD, Frota, MM, Bastos, MDSR et al.. Halochromic Polystyrene Nanofibers Obtained by Solution Blow Spinning for Wine pH Sensing. Sensors (Basel). 2020;20 (2):. doi: 10.3390/s20020417. PubMed PMID:31940816 PubMed Central PMC7014295.
  15. Press, VG, Arora, VM, Kelly, CA, Carey, KA, White, SR, Wan, W et al.. Effectiveness of Virtual vs In-Person Inhaler Education for Hospitalized Patients With Obstructive Lung Disease: A Randomized Clinical Trial. JAMA Netw Open. 2020;3 (1):e1918205. doi: 10.1001/jamanetworkopen.2019.18205. PubMed PMID:31899529 PubMed Central PMC6991242.
  16. Li, W, Shu, S, Cheng, L, Hao, X, Wang, L, Wu, Y et al.. Fasting serum total bile acid level is associated with coronary artery disease, myocardial infarction and severity of coronary lesions. Atherosclerosis. 2020;292 :193-200. doi: 10.1016/j.atherosclerosis.2019.11.026. PubMed PMID:31811964 .
  17. Kumar, A, Sankar, TK, Sethi, SS, Ambade, B. Characteristics, toxicity, source identification and seasonal variation of atmospheric polycyclic aromatic hydrocarbons over East India. Environ Sci Pollut Res Int. 2020;27 (1):678-690. doi: 10.1007/s11356-019-06882-5. PubMed PMID:31808094 .
  18. Li, X, Liu, W, Zhang, C, Song, P, Wang, J. Fate of Phthalic Acid Esters (PAEs) in Typical Greenhouse Soils of Different Cultivation Ages. Bull Environ Contam Toxicol. 2020;104 (2):301-306. doi: 10.1007/s00128-019-02756-1. PubMed PMID:31784767 .
  19. Bajerski, F, Bürger, A, Glasmacher, B, Keller, ERJ, Müller, K, Mühldorfer, K et al.. Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples. Appl. Microbiol. Biotechnol. 2020;104 (1):131-144. doi: 10.1007/s00253-019-10242-1. PubMed PMID:31781817 PubMed Central PMC6942587.
  20. Qiu, X, Chen, W, Luo, Y, Wang, Y, Wang, Y, Guo, H et al.. Highly sensitive α-amanitin sensor based on molecularly imprinted photonic crystals. Anal. Chim. Acta. 2020;1093 :142-149. doi: 10.1016/j.aca.2019.09.066. PubMed PMID:31735207 .
Search PubMed
  1. Fernandez, J, Doña, I. Diagnosing and managing patients with drug hypersensitivity. Expert Rev Clin Immunol. 2018;14 (1):29-41. doi: 10.1080/1744666X.2018.1410059. PubMed PMID:29202594 .
Search PubMed
  1. Campo, P, Del Carmen Plaza-Seron, M, Eguiluz-Gracia, I, Verge, J, Galindo, L, Barrionuevo, E et al.. Direct intranasal application of the solid phase of ImmunoCAP® increases nasal specific immunoglobulin E detection in local allergic rhinitis patients. Int Forum Allergy Rhinol. 2018;8 (1):15-19. doi: 10.1002/alr.22039. PubMed PMID:29136342 .
Search PubMed
  1. Augé, J, Vent, J, Agache, I, Airaksinen, L, Campo Mozo, P, Chaker, A et al.. EAACI Position paper on the standardization of nasal allergen challenges. Allergy. 2018;73 (8):1597-1608. doi: 10.1111/all.13416. PubMed PMID:29377177 .
Search PubMed
  1. Le Guével, X, Henry, M, Motto-Ros, V, Longo, E, Montañez, MI, Pelascini, F et al.. Elemental and optical imaging evaluation of zwitterionic gold nanoclusters in glioblastoma mouse models. Nanoscale. 2018;10 (39):18657-18664. doi: 10.1039/c8nr05299a. PubMed PMID:30264838 .
Search PubMed
  1. Torres, MJ, Fernández, TD. Highlights of the 8th Drug Hypersensitivity Meeting: Amsterdam, April 19-21, 2018. Allergy. 2018;73 (10):1941-1943. doi: 10.1111/all.13574. PubMed PMID:30043992 .
Search PubMed
  1. Rondón, C, Eguíluz-Gracia, I, Shamji, MH, Layhadi, JA, Salas, M, Torres, MJ et al.. IgE Test in Secretions of Patients with Respiratory Allergy. Curr Allergy Asthma Rep. 2018;18 (12):67. doi: 10.1007/s11882-018-0821-7. PubMed PMID:30317418 .
Search PubMed
  1. Palomares, F, Gomez, F, Bogas, G, Campo, P, Perkins, JR, Diaz-Perales, A et al.. Immunological Changes Induced in Peach Allergy Patients with Systemic Reactions by Pru p 3 Sublingual Immunotherapy. Mol Nutr Food Res. 2018;62 (3):. doi: 10.1002/mnfr.201700669. PubMed PMID:29105313 .
Search PubMed
  1. Rodriguez, MJ, Wangorsch, A, Gomez, F, Schülke, S, Torres, MJ, Vieths, S et al.. Immunotherapy with Native Molecule rather than Hypoallergenic Variant of Pru p 3, the Major Peach Allergen, Shows Beneficial Effects in Mice. J Immunol Res. 2018;2018 :3479185. doi: 10.1155/2018/3479185. PubMed PMID:30009186 PubMed Central PMC6020533.
Search PubMed
  1. Wise, SK, Lin, SY, Toskala, E, Orlandi, RR, Akdis, CA, Alt, JA et al.. International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis. Int Forum Allergy Rhinol. 2018;8 (2):108-352. doi: 10.1002/alr.22073. PubMed PMID:29438602 PubMed Central PMC7286723.
Search PubMed
  1. Rondón, C, Eguiluz-Gracia, I, Campo, P. Is the evidence of local allergic rhinitis growing?. Curr Opin Allergy Clin Immunol. 2018;18 (4):342-349. doi: 10.1097/ACI.0000000000000456. PubMed PMID:29847361 .
Search PubMed
  1. Rondon, C, Campo, P, Eguiluz-Gracia, I, Plaza, C, Bogas, G, Galindo, P et al.. Local allergic rhinitis is an independent rhinitis phenotype: The results of a 10-year follow-up study. Allergy. 2018;73 (2):470-478. doi: 10.1111/all.13272. PubMed PMID:28833265 .
Search PubMed
  1. Pascal, M, Perez-Gordo, M, Caballero, T, Escribese, MM, Lopez Longo, MN, Luengo, O et al.. Microbiome and Allergic Diseases. Front Immunol. 2018;9 :1584. doi: 10.3389/fimmu.2018.01584. PubMed PMID:30065721 PubMed Central PMC6056614.
Search PubMed
  1. García-Martín, E, Ramos, MI, Cornejo-García, JA, Galván, S, Perkins, JR, Rodríguez-Santos, L et al.. Missense Gamma-Aminobutyric Acid Receptor Polymorphisms Are Associated with Reaction Time, Motor Time, and Ethanol Effects in Vivo. Front Cell Neurosci. 2018;12 :10. doi: 10.3389/fncel.2018.00010. PubMed PMID:29445327 PubMed Central PMC5797743.
Search PubMed
  1. Doña, I, Barrionuevo, E, Salas, M, Laguna, JJ, Agúndez, J, García-Martín, E et al.. NSAIDs-hypersensitivity often induces a blended reaction pattern involving multiple organs. Sci Rep. 2018;8 (1):16710. doi: 10.1038/s41598-018-34668-1. PubMed PMID:30420763 PubMed Central PMC6232098.
Search PubMed
  1. Lu, Q, Huang, T, Zhou, J, Zeng, Y, Wu, C, Liu, M et al.. Limitation-induced fluorescence enhancement of carbon nanoparticles and their application for glucose detection. Spectrochim Acta A Mol Biomol Spectrosc. 2020;244 :118893. doi: 10.1016/j.saa.2020.118893. PubMed PMID:32916589 .
  2. Cusano, AM, Aliberti, A, Cusano, A, Ruvo, M. Detection of small DNA fragments by biolayer interferometry. Anal. Biochem. 2020;607 :113898. doi: 10.1016/j.ab.2020.113898. PubMed PMID:32777266 .
  3. Chen, J, Feng, S, Chen, M, Li, P, Yang, Y, Zhang, J et al.. In Vivo Dynamic Monitoring of Bacterial Infection by NIR-II Fluorescence Imaging. Small. 2020;16 (34):e2002054. doi: 10.1002/smll.202002054. PubMed PMID:32715565 .
  4. Ierardi, AM, Pavilonis, B. Heat stress risk among New York City public school kitchen workers: a quantitative exposure assessment. J Occup Environ Hyg. ;17 (7-8):353-363. doi: 10.1080/15459624.2020.1776300. PubMed PMID:32552608 .
  5. Blitstein, JL, Guthrie, JF, Rains, C. Low-Income Parents' Use of Front-of-Package Nutrition Labels in a Virtual Supermarket. J Nutr Educ Behav. 2020;52 (9):850-858. doi: 10.1016/j.jneb.2020.04.003. PubMed PMID:32475704 .
  6. Zhang, K, Sun, D, Duan, C, Chen, H, Din, AU, Kong, X et al.. Application of a Faecalibacterium 16S rDNA genetic marker for species identification of dog fecal waste. Environ Sci Pollut Res Int. 2020;27 (24):30615-30624. doi: 10.1007/s11356-020-09369-w. PubMed PMID:32472511 .
  7. Bharali, B, Talukdar, H, Phukan, P, Das, DK. A New Schiff Base Based Fluorescent Sensor for Al(III) Based on 2-Hydroxyacetophenone and o-Phenylenediamine. J Fluoresc. 2020;30 (4):751-757. doi: 10.1007/s10895-020-02527-w. PubMed PMID:32410084 .
  8. Vujacic-Mirski, K, Bruns, K, Kalinovic, S, Oelze, M, Kröller-Schön, S, Steven, S et al.. Development of an Analytical Assay for Electrochemical Detection and Quantification of Protein-Bound 3-Nitrotyrosine in Biological Samples and Comparison with Classical, Antibody-Based Methods. Antioxidants (Basel). 2020;9 (5):. doi: 10.3390/antiox9050388. PubMed PMID:32384768 PubMed Central PMC7278855.
  9. Planelló, R, Herrero, O, García, P, Beltrán, EM, Llorente, L, Sánchez-Argüello, P et al.. Developmental/reproductive effects and gene expression variations in Chironomus riparius after exposure to reclaimed water and its fortification with carbamazepine and triclosan. Water Res. 2020;178 :115790. doi: 10.1016/j.watres.2020.115790. PubMed PMID:32334179 .
  10. Liu, Y, Zhao, C, Zhao, W, Zhang, H, Yao, S, Shi, Y et al.. Multi-functional MnO2-doped Fe3O4 nanoparticles as an artificial enzyme for the colorimetric detection of bacteria. Anal Bioanal Chem. 2020;412 (13):3135-3140. doi: 10.1007/s00216-020-02563-2. PubMed PMID:32285182 .
  11. Casucci, C, De Bernardi, A, D'Amato, R, Businelli, D, Vischetti, C. Zeolite and bentonite as nickel sequestrants in carbonation lime coming from the sugar industry. Environ Sci Pollut Res Int. 2020;27 (15):18803-18809. doi: 10.1007/s11356-020-08469-x. PubMed PMID:32207012 .
  12. Liu, Q, Huang, C, Chris Le, X. Arsenic species in electronic cigarettes: Determination and potential health risk. J Environ Sci (China). 2020;91 :168-176. doi: 10.1016/j.jes.2020.01.023. PubMed PMID:32172965 .
  13. Jiang, Y, Xiao, X, Li, C, Luo, Y, Chen, S, Shi, G et al.. Facile Ratiometric Electrochemical Sensor for In Vivo/Online Repetitive Measurements of Cerebral Ascorbic Acid in Brain Microdiaysate. Anal. Chem. 2020;92 (5):3981-3989. doi: 10.1021/acs.analchem.9b05484. PubMed PMID:32037799 .
  14. Miranda, KWE, Natarelli, CVL, Thomazi, AC, Ferreira, GMD, Frota, MM, Bastos, MDSR et al.. Halochromic Polystyrene Nanofibers Obtained by Solution Blow Spinning for Wine pH Sensing. Sensors (Basel). 2020;20 (2):. doi: 10.3390/s20020417. PubMed PMID:31940816 PubMed Central PMC7014295.
  15. Press, VG, Arora, VM, Kelly, CA, Carey, KA, White, SR, Wan, W et al.. Effectiveness of Virtual vs In-Person Inhaler Education for Hospitalized Patients With Obstructive Lung Disease: A Randomized Clinical Trial. JAMA Netw Open. 2020;3 (1):e1918205. doi: 10.1001/jamanetworkopen.2019.18205. PubMed PMID:31899529 PubMed Central PMC6991242.
  16. Li, W, Shu, S, Cheng, L, Hao, X, Wang, L, Wu, Y et al.. Fasting serum total bile acid level is associated with coronary artery disease, myocardial infarction and severity of coronary lesions. Atherosclerosis. 2020;292 :193-200. doi: 10.1016/j.atherosclerosis.2019.11.026. PubMed PMID:31811964 .
  17. Kumar, A, Sankar, TK, Sethi, SS, Ambade, B. Characteristics, toxicity, source identification and seasonal variation of atmospheric polycyclic aromatic hydrocarbons over East India. Environ Sci Pollut Res Int. 2020;27 (1):678-690. doi: 10.1007/s11356-019-06882-5. PubMed PMID:31808094 .
  18. Li, X, Liu, W, Zhang, C, Song, P, Wang, J. Fate of Phthalic Acid Esters (PAEs) in Typical Greenhouse Soils of Different Cultivation Ages. Bull Environ Contam Toxicol. 2020;104 (2):301-306. doi: 10.1007/s00128-019-02756-1. PubMed PMID:31784767 .
  19. Bajerski, F, Bürger, A, Glasmacher, B, Keller, ERJ, Müller, K, Mühldorfer, K et al.. Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples. Appl. Microbiol. Biotechnol. 2020;104 (1):131-144. doi: 10.1007/s00253-019-10242-1. PubMed PMID:31781817 PubMed Central PMC6942587.
  20. Qiu, X, Chen, W, Luo, Y, Wang, Y, Wang, Y, Guo, H et al.. Highly sensitive α-amanitin sensor based on molecularly imprinted photonic crystals. Anal. Chim. Acta. 2020;1093 :142-149. doi: 10.1016/j.aca.2019.09.066. PubMed PMID:31735207 .
Search PubMed
  1. Laguna, JJ, Archilla, J, Doña, I, Corominas, M, Gastaminza, G, Mayorga, C et al.. Practical Guidelines for Perioperative Hypersensitivity Reactions. J Investig Allergol Clin Immunol. ;28 (4):216-232. doi: 10.18176/jiaci.0236. PubMed PMID:29411702 .
Search PubMed
  1. Eguiluz-Gracia, I, Tay, TR, Hew, M, Escribese, MM, Barber, D, O'Hehir, RE et al.. Recent developments and highlights in biomarkers in allergic diseases and asthma. Allergy. 2018;73 (12):2290-2305. doi: 10.1111/all.13628. PubMed PMID:30289997 .
Search PubMed
  1. Rondón, C, Blanca-López, N, Campo, P, Mayorga, C, Jurado-Escobar, R, Torres, MJ et al.. Specific immunotherapy in local allergic rhinitis: A randomized, double-blind placebo-controlled trial with Phleum pratense subcutaneous allergen immunotherapy. Allergy. 2018;73 (4):905-915. doi: 10.1111/all.13350. PubMed PMID:29168570 .
Search PubMed
  1. Laguna, JJ, Bogas, G, Salas, M, Mayorga, C, Dionicio, J, Gonzalez-Mendiola, R et al.. The Basophil Activation Test Can Be of Value for Diagnosing Immediate Allergic Reactions to Omeprazole. J Allergy Clin Immunol Pract. ;6 (5):1628-1636.e2. doi: 10.1016/j.jaip.2017.12.001. PubMed PMID:29339127 .
Search PubMed
  1. Muraro, A, Fernandez-Rivas, M, Beyer, K, Cardona, V, Clark, A, Eller, E et al.. The urgent need for a harmonized severity scoring system for acute allergic reactions. Allergy. 2018;73 (9):1792-1800. doi: 10.1111/all.13408. PubMed PMID:29331045 .
Search PubMed
  1. Salas, M, Fernández-Santamaría, R, Mayorga, C, Barrionuevo, E, Ariza, A, Posadas, T et al.. Use of the Basophil Activation Test May Reduce the Need for Drug Provocation in Amoxicillin-Clavulanic Allergy. J Allergy Clin Immunol Pract. ;6 (3):1010-1018.e2. doi: 10.1016/j.jaip.2017.08.009. PubMed PMID:28964705 .
Search PubMed
  1. Tanno, LK, Torres, MJ, Castells, M, Demoly, P, Joint Allergy Academies. What can we learn in drug allergy management from World Health Organization's international classifications?. Allergy. 2018;73 (5):987-992. doi: 10.1111/all.13335. PubMed PMID:29105793 .
Search PubMed
  1. Murciano, C, Cazorla-Vázquez, S, Gutiérrez, J, Hijano, JA, Ruiz-Sánchez, J, Mesa-Almagro, L et al.. Widening control of fin inter-rays in zebrafish and inferences about actinopterygian fins. J. Anat. 2018;232 (5):783-805. doi: 10.1111/joa.12785. PubMed PMID:29441573 PubMed Central PMC6480674.
Search PubMed
  1. De Schryver, E, Derycke, L, Campo, P, Gabriels, E, Joos, GF, Van Zele, T et al.. Alcohol hyper-responsiveness in chronic rhinosinusitis with nasal polyps. Clin. Exp. Allergy. 2017;47 (2):245-253. doi: 10.1111/cea.12836. PubMed PMID:27770460 .
Search PubMed
  1. Escribese, MM, Rosace, D, Chivato, T, Fernández, TD, Corbí, AL, Barber, D et al.. Alternative Anaphylactic Routes: The Potential Role of Macrophages. Front Immunol. 2017;8 :515. doi: 10.3389/fimmu.2017.00515. PubMed PMID:28533777 PubMed Central PMC5421149.
Search PubMed
  1. Sánchez-Gómez, FJ, González-Morena, JM, Vida, Y, Pérez-Inestrosa, E, Blanca, M, Torres, MJ et al.. Amoxicillin haptenates intracellular proteins that can be transported in exosomes to target cells. Allergy. 2017;72 (3):385-396. doi: 10.1111/all.12958. PubMed PMID:27319758 .
Search PubMed
  1. Torres, MJ, Romano, A, Celik, G, Demoly, P, Khan, DA, Macy, E et al.. Approach to the diagnosis of drug hypersensitivity reactions: similarities and differences between Europe and North America. Clin Transl Allergy. 2017;7 :7. doi: 10.1186/s13601-017-0144-0. PubMed PMID:28293415 PubMed Central PMC5347172.
Search PubMed
  1. Fauquert, JL, Jedrzejczak-Czechowicz, M, Rondon, C, Calder, V, Silva, D, Kvenshagen, BK et al.. Conjunctival allergen provocation test : guidelines for daily practice. Allergy. 2017;72 (1):43-54. doi: 10.1111/all.12986. PubMed PMID:27430124 .
Search PubMed
  1. Gonzalez, M, Doña, I, Palomares, F, Campo, P, Rodriguez, MJ, Rondon, C et al.. Dermatophagoides pteronyssinus immunotherapy changes the T-regulatory cell activity. Sci Rep. 2017;7 (1):11949. doi: 10.1038/s41598-017-12261-2. PubMed PMID:28931869 PubMed Central PMC5607227.
Search PubMed
  1. Doña, I, Barrionuevo, E, Salas, M, Cornejo-García, JA, Perkins, JR, Bogas, G et al.. Natural evolution in patients with nonsteroidal anti-inflammatory drug-induced urticaria/angioedema. Allergy. 2017;72 (9):1346-1355. doi: 10.1111/all.13147. PubMed PMID:28226401 .
Search PubMed
  1. Quirce, S, Campo, P, Domínguez-Ortega, J, Fernández-Nieto, M, Gómez-Torrijos, E, Martínez-Arcediano, A et al.. New developments in work-related asthma. Expert Rev Clin Immunol. 2017;13 (3):271-281. doi: 10.1080/1744666X.2017.1239529. PubMed PMID:27653257 .
Search PubMed
  1. Rondón, C, Bogas, G, Barrionuevo, E, Blanca, M, Torres, MJ, Campo, P et al.. Nonallergic rhinitis and lower airway disease. Allergy. 2017;72 (1):24-34. doi: 10.1111/all.12988. PubMed PMID:27439024 .
Search PubMed
  1. Hellings, PW, Klimek, L, Cingi, C, Agache, I, Akdis, C, Bachert, C et al.. Non-allergic rhinitis: Position paper of the European Academy of Allergy and Clinical Immunology. Allergy. 2017;72 (11):1657-1665. doi: 10.1111/all.13200. PubMed PMID:28474799 .
Search PubMed
  1. Salas, M, Laguna, JJ, Doña, I, Barrionuevo, E, Fernandez-Santamaría, R, Ariza, A et al.. Patients Taking Amoxicillin-Clavulanic Can Become Simultaneously Sensitized to Both Drugs. J Allergy Clin Immunol Pract. ;5 (3):694-702.e3. doi: 10.1016/j.jaip.2017.02.007. PubMed PMID:28342830 .
Search PubMed
  1. Muraro, A, Lemanske, RF Jr, Castells, M, Torres, MJ, Khan, D, Simon, HU et al.. Precision medicine in allergic disease-food allergy, drug allergy, and anaphylaxis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology. Allergy. 2017;72 (7):1006-1021. doi: 10.1111/all.13132. PubMed PMID:28122115 .
Search PubMed
  1. Rodriguez, MJ, Mascaraque, A, Ramos-Soriano, J, Torres, MJ, Perkins, JR, Gomez, F et al.. Pru p 3-Epitope-based sublingual immunotherapy in a murine model for the treatment of peach allergy. Mol Nutr Food Res. 2017;61 (10):. doi: 10.1002/mnfr.201700110. PubMed PMID:28586170 .
Search PubMed
  1. Farzan, N, Vijverberg, SJ, Andiappan, AK, Arianto, L, Berce, V, Blanca-López, N et al.. Rationale and design of the multiethnic Pharmacogenomics in Childhood Asthma consortium. Pharmacogenomics. 2017;18 (10):931-943. doi: 10.2217/pgs-2017-0035. PubMed PMID:28639505 PubMed Central PMC5967359.
Search PubMed
  1. Doña, I, Moreno, E, Pérez-Sánchez, N, Andreu, I, Fernandez de Rojas, DH, Torres, MJ et al.. Response to Ebo et al., Letter to the Editor Regarding Update on Quinolone Allergy. Curr Allergy Asthma Rep. 2017;17 (10):75. doi: 10.1007/s11882-017-0743-9. PubMed PMID:28980113 .
Search PubMed
  1. Gomez, F, Bogas, G, Gonzalez, M, Campo, P, Salas, M, Diaz-Perales, A et al.. The clinical and immunological effects of Pru p 3 sublingual immunotherapy on peach and peanut allergy in patients with systemic reactions. Clin. Exp. Allergy. 2017;47 (3):339-350. doi: 10.1111/cea.12901. PubMed PMID:28160513 .
Search PubMed
  1. Mayorga, C, Doña, I, Perez-Inestrosa, E, Fernández, TD, Torres, MJ. The Value of In Vitro Tests to DiminishDrug Challenges. Int J Mol Sci. 2017;18 (6):. doi: 10.3390/ijms18061222. PubMed PMID:28590437 PubMed Central PMC5486045.
Search PubMed
  1. Doña, I, Moreno, E, Pérez-Sánchez, N, Andreu, I, Hernández Fernandez de Rojas, D, Torres, MJ et al.. Update on Quinolone Allergy. Curr Allergy Asthma Rep. 2017;17 (8):56. doi: 10.1007/s11882-017-0725-y. PubMed PMID:28752367 .
Search PubMed
  1. Jurado-Escobar, R, Perkins, JR, García-Martín, E, Isidoro-García, M, Doña, I, Torres, MJ et al.. Update on the Genetic Basis of Drug Hypersensitivity Reactions. J Investig Allergol Clin Immunol. ;27 (6):336-345. doi: 10.18176/jiaci.0199. PubMed PMID:29199960 .
Search PubMed
  1. Amo, G, García-Menaya, J, Campo, P, Cordobés, C, Plaza Serón, MC, Ayuso, P et al.. A Nonsynonymous FCER1B SNP is Associated with Risk of Developing Allergic Rhinitis and with IgE Levels. Sci Rep. 2016;6 :19724. doi: 10.1038/srep19724. PubMed PMID:26792385 PubMed Central PMC4726269.
Search PubMed
  1. Cornejo-García, JA, Romano, A, Guéant-Rodríguez, RM, Oussalah, A, Blanca-López, N, Gaeta, F et al.. A non-synonymous polymorphism in galectin-3 lectin domain is associated with allergic reactions to beta-lactam antibiotics. Pharmacogenomics J. 2016;16 (1):79-82. doi: 10.1038/tpj.2015.24. PubMed PMID:25869013 .
Search PubMed
  1. Blanca-López, N, Pérez-Sánchez, N, Agúndez, JA, García-Martin, E, Torres, MJ, Cornejo-García, JA et al.. Allergic Reactions to Metamizole: Immediate and Delayed Responses. Int. Arch. Allergy Immunol. 2016;169 (4):223-30. doi: 10.1159/000444798. PubMed PMID:27224978 .
Search PubMed
  1. Bogas, G, Pérez-Sánchez, N, Andreu, I, Doña, I, Perkins, JR, Blanca, M et al.. Anaphylaxis to 2 NSAIDs in a Patient Who Tolerated ASA. J Investig Allergol Clin Immunol. 2016;26 (4):266-8. doi: 10.18176/jiaci.0066. PubMed PMID:27470646 .
Search PubMed
  1. Pérez-Alzate, D, Blanca-López, N, Doña, I, Agúndez, JA, García-Martín, E, Cornejo-García, JA et al.. Asthma and Rhinitis Induced by Selective Immediate Reactions to Paracetamol and Non-steroidal Anti-inflammatory Drugs in Aspirin Tolerant Subjects. Front Pharmacol. 2016;7 :215. doi: 10.3389/fphar.2016.00215. PubMed PMID:27489545 PubMed Central PMC4951487.
Search PubMed
  1. Ariza, A, Montanez, MI, Fernandez, TD, Perkins, JR, Mayorga, C. Cellular Tests for the Evaluation of Drug Hypersensitivity. Curr. Pharm. Des. 2016;22 (45):6773-6783. doi: 10.2174/1381612822666161107165917. PubMed PMID:27829334 .
Search PubMed
  1. Rojano, E, Ranea, JA, Perkins, JR. Characterisation of non-coding genetic variation in histamine receptors using AnNCR-SNP. Amino Acids. 2016;48 (10):2433-42. doi: 10.1007/s00726-016-2265-5. PubMed PMID:27270572 .
Search PubMed
  1. Martínez-Aranguren, R, Martínez-Botas, J, Díaz-Perales, A, Villalba, M, de la Hoz, B, Gómez, F et al.. Clinical Performance of Commercial ISAC 112 Allergen Microarray Versus Noncommercial RIRAAF Platform for the Diagnosis of Plant Food and Olive Pollen Allergies. J Investig Allergol Clin Immunol. 2016;26 (3):185-7. doi: 10.18176/jiaci.00168. PubMed PMID:27326986 .
Search PubMed
  1. Rosado Ingelmo, A, Doña Diaz, I, Cabañas Moreno, R, Moya Quesada, MC, García-Avilés, C, García Nuñez, I et al.. Clinical Practice Guidelines for Diagnosis and Management of Hypersensitivity Reactions to Contrast Media. J Investig Allergol Clin Immunol. 2016;26 (3):144-55; quiz 2 p following 155. doi: 10.18176/jiaci.0058. PubMed PMID:27326981 .
Search PubMed
  1. Plaza-Serón, Mdel C, Ayuso, P, Pérez-Sánchez, N, Doña, I, Blanca-Lopez, N, Flores, C et al.. Copy number variation in ALOX5 and PTGER1 is associated with NSAIDs-induced urticaria and/or angioedema. Pharmacogenet. Genomics. 2016;26 (6):280-7. doi: 10.1097/FPC.0000000000000216. PubMed PMID:26959713 .
Search PubMed
  1. Mayorga, C, Perez-Inestrosa, E, Molina, N, Montañez, MI. Development of nanostructures in the diagnosis of drug hypersensitivity reactions. Curr Opin Allergy Clin Immunol. 2016;16 (4):300-7. doi: 10.1097/ACI.0000000000000282. PubMed PMID:27257940 .
Search PubMed
  1. Brockow, K, Aberer, W, Atanaskovic-Markovic, M, Bavbek, S, Bircher, A, Bilo, B et al.. Drug allergy passport and other documentation for patients with drug hypersensitivity - An ENDA/EAACI Drug Allergy Interest Group Position Paper. Allergy. 2016;71 (11):1533-1539. doi: 10.1111/all.12929. PubMed PMID:27145347 .
Search PubMed
  1. Rondón, C, Campo, P, Salas, M, Aranda, A, Molina, A, González, M et al.. Efficacy and safety of D. pteronyssinus immunotherapy in local allergic rhinitis: a double-blind placebo-controlled clinical trial. Allergy. 2016;71 (7):1057-61. doi: 10.1111/all.12889. PubMed PMID:27008542 .
Search PubMed
  1. Amo, G, Cornejo-García, JA, García-Menaya, JM, Cordobes, C, Torres, MJ, Esguevillas, G et al.. FCERI and Histamine Metabolism Gene Variability in Selective Responders to NSAIDS. Front Pharmacol. 2016;7 :353. doi: 10.3389/fphar.2016.00353. PubMed PMID:27746735 PubMed Central PMC5040715.
Search PubMed
  1. Plaza-Serón, Mdel C, Blanca-López, N, Pérez-Sánchez, N, Doña, I, Acosta-Herrera, M, Pino-Yanes, M et al.. Genetic Variants of Thymic Stromal Lymphopoietin in Nonsteroidal Anti-Inflammatory Drug-Induced Urticaria/Angioedema. Int. Arch. Allergy Immunol. 2016;169 (4):249-55. doi: 10.1159/000444797. PubMed PMID:27240835 .
Search PubMed
  1. Dona, I, Salas, M, Perkins, JR, Barrionuevo, E, Gaeta, F, Cornejo-Garcia, JA et al.. Hypersensitivity Reactions to Non-Steroidal Anti-Inflammatory Drugs. Curr. Pharm. Des. 2016;22 (45):6784-6802. doi: 10.2174/1381612822666160928142814. PubMed PMID:27779082 .
Search PubMed
  1. Fernández, TD, Ariza, A, Palomares, F, Montañez, MI, Salas, M, Martín-Serrano, A et al.. Hypersensitivity to fluoroquinolones: The expression of basophil activation markers depends on the clinical entity and the culprit fluoroquinolone. Medicine (Baltimore). 2016;95 (23):e3679. doi: 10.1097/MD.0000000000003679. PubMed PMID:27281069 PubMed Central PMC4907647.
Search PubMed
  1. Blanca-López, N, Pérez-Alzate, D, Andreu, I, Doña, I, Agúndez, JA, García-Martín, E et al.. Immediate hypersensitivity reactions to ibuprofen and other arylpropionic acid derivatives. Allergy. 2016;71 (7):1048-56. doi: 10.1111/all.12855. PubMed PMID:26841325 .
Search PubMed
  1. Oussalah, A, Mayorga, C, Blanca, M, Barbaud, A, Nakonechna, A, Cernadas, J et al.. Genetic variants associated with drugs-induced immediate hypersensitivity reactions: a PRISMA-compliant systematic review. Allergy. 2016;71 (4):443-62. doi: 10.1111/all.12821. PubMed PMID:26678823 .
Search PubMed
  1. Goikoetxea, MJ, D'Amelio C M,, Martínez-Aranguren, R, Gamboa, P, Garcia, BE, Gómez, F et al.. Is Microarray Analysis Really Useful and Sufficient to Diagnose Nut Allergy in the Mediterranean Area?. J Investig Allergol Clin Immunol. 2016;26 (1):31-9. . PubMed PMID:27012014 .
Search PubMed
  1. García, BE, Martínez-Aranguren, R, Bernard Alonso, A, Gamboa, P, Feo Brito, F, Bartra, J et al.. Is the ISAC 112 Microarray Useful in the Diagnosis of Pollinosis in Spain?. J Investig Allergol Clin Immunol. 2016;26 (2):92-9. doi: 10.18176/jiaci.0052. PubMed PMID:27164624 .
Search PubMed
  1. Campo, P, Salas, M, Blanca-López, N, Rondón, C. Local Allergic Rhinitis. Immunol Allergy Clin North Am. 2016;36 (2):321-32. doi: 10.1016/j.iac.2015.12.008. PubMed PMID:27083105 .
Search PubMed
  1. Quirce, S, Vandenplas, O, Campo, P, Cruz, MJ, de Blay, F, Koschel, D et al.. Occupational hypersensitivity pneumonitis: an EAACI position paper. Allergy. 2016;71 (6):765-79. doi: 10.1111/all.12866. PubMed PMID:26913451 .
Search PubMed
  1. Cornejo-García, JA, Perkins, JR, Jurado-Escobar, R, García-Martín, E, Agúndez, JA, Viguera, E et al.. Pharmacogenomics of Prostaglandin and Leukotriene Receptors. Front Pharmacol. 2016;7 :316. doi: 10.3389/fphar.2016.00316. PubMed PMID:27708579 PubMed Central PMC5030812.
Search PubMed
  1. Hoffmann, HJ, Knol, EF, Ferrer, M, Mayorga, L, Sabato, V, Santos, AF et al.. Pros and Cons of Clinical Basophil Testing (BAT). Curr Allergy Asthma Rep. 2016;16 (8):56. doi: 10.1007/s11882-016-0633-6. PubMed PMID:27411319 .
Search PubMed
  1. Ariza, A, García-Martín, E, Salas, M, Montañez, MI, Mayorga, C, Blanca-Lopez, N et al.. Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole. Sci Rep. 2016;6 :23845. doi: 10.1038/srep23845. PubMed PMID:27030298 PubMed Central PMC4814906.
Search PubMed
  1. Kespohl, S, Campo, P, Zahradnik, E, Maryska, S, Aranda-Guerrero, A, Rodriguez, J et al.. Quantification of obeche wood allergen: Development of a sensitive sandwich-ELISA for occupational exposure assessment. J. Toxicol. Environ. Health Part A. 2016;79 (22-23):1070-1077. doi: 10.1080/15287394.2016.1219577. PubMed PMID:27924719 .
Search PubMed
  1. Vega, F, Panizo, C, Dordal, MT, González, ML, Velázquez, E, Valero, A et al.. Relationship between respiratory and food allergy and evaluation of preventive measures. Allergol Immunopathol (Madr). ;44 (3):263-75. doi: 10.1016/j.aller.2015.05.008. PubMed PMID:26316421 .
Search PubMed
  1. Upton, A, Trelles, O, Cornejo-García, JA, Perkins, JR. Review: High-performance computing to detect epistasis in genome scale data sets. Brief. Bioinformatics. 2016;17 (3):368-79. doi: 10.1093/bib/bbv058. PubMed PMID:26272945 .
Search PubMed
  1. Blanca-Lopez, N, Campo, P, Salas, M, García Rodríguez, C, Palomares, F, Blanca, M et al.. Seasonal Local Allergic Rhinitis in Areas With High Concentrations of Grass Pollen. J Investig Allergol Clin Immunol. 2016;26 (2):83-91. doi: 10.18176/jiaci.0018. PubMed PMID:27164623 .
Search PubMed
  1. Lacombe-Barrios, J, Salas, M, Gómez, F, Doña, I, Ariza, A, Mayorga, C et al.. The Addition of Benzylpenicillin Does Not Increase the Skin Test Sensitivity Obtained With Classic β-Lactam Determinants. J Investig Allergol Clin Immunol. 2016;26 (1):52-4. . PubMed PMID:27012018 .
Search PubMed
  1. Cornejo-García, JA, Jurado-Escobar, R, Doña, I, Perkins, JR, Agúndez, JA, García-Martín, E et al.. The Genetics of Drug Hypersensitivity Reactions. J Investig Allergol Clin Immunol. 2016;26 (4):222-32, quiz next two pages. doi: 10.18176/jiaci.0078. PubMed PMID:27375032 .
Search PubMed
  1. Ariza, A, Mayorga, C, Salas, M, Doña, I, Martín-Serrano, Á, Pérez-Inestrosa, E et al.. The influence of the carrier molecule on amoxicillin recognition by specific IgE in patients with immediate hypersensitivity reactions to betalactams. Sci Rep. 2016;6 :35113. doi: 10.1038/srep35113. PubMed PMID:27731424 PubMed Central PMC5059705.
Search PubMed
  1. Torres, MJ, Montañez, MI, Ariza, A, Salas, M, Fernandez, TD, Barbero, N et al.. The role of IgE recognition in allergic reactions to amoxicillin and clavulanic acid. Clin. Exp. Allergy. 2016;46 (2):264-74. doi: 10.1111/cea.12689. PubMed PMID:26662186 .
Search PubMed
  1. Martín-Pedraza, L, González, M, Gómez, F, Blanca-López, N, Garrido-Arandia, M, Rodríguez, R et al.. Two nonspecific lipid transfer proteins (nsLTPs) from tomato seeds are associated to severe symptoms of tomato-allergic patients. Mol Nutr Food Res. 2016;60 (5):1172-82. doi: 10.1002/mnfr.201500782. PubMed PMID:26840232 .
Search PubMed
  1. Torres, MJ, Salas, M, Ariza, A, Fernández, TD. Understanding the mechanisms in accelerated drug reactions. Curr Opin Allergy Clin Immunol. 2016;16 (4):308-14. doi: 10.1097/ACI.0000000000000285. PubMed PMID:27285487 .
Search PubMed
  1. Sastre, J, Rodríguez, F, Campo, P, Laffond, E, Marín, A, Alonso, MD et al.. Adverse reactions to immunotherapy are associated with different patterns of sensitization to grass allergens. Allergy. 2015;70 (5):598-600. doi: 10.1111/all.12575. PubMed PMID:25631061 .
Search PubMed
  1. Ayuso, P, Plaza-Serón, Mdel C, Doña, I, Blanca-López, N, Campo, P, Cornejo-García, JA et al.. Association study of genetic variants in PLA2G4A, PLCG1, LAT, SYK, and TNFRS11A genes in NSAIDs-induced urticaria and/or angioedema patients. Pharmacogenet. Genomics. 2015;25 (12):618-21. doi: 10.1097/FPC.0000000000000179. PubMed PMID:26398624 .
Search PubMed
  1. Lopez, S, Gomez, E, Torres, MJ, Pozo, D, Fernandez, TD, Ariza, A et al.. Betalactam antibiotics affect human dendritic cells maturation through MAPK/NF-kB systems. Role in allergic reactions to drugs. Toxicol. Appl. Pharmacol. 2015;288 (3):289-99. doi: 10.1016/j.taap.2015.08.001. PubMed PMID:26254762 .
Search PubMed
  1. Rondón, C, Dávila, I, Navarro Pulido, AM, Sánchez, MC, Montoro, J, Matheu, V et al.. Clinical Management and Use of Health Care Resources in the Treatment of Nasal Polyposis in Spanish Allergy Centers: The POLAR Study. J Investig Allergol Clin Immunol. 2015;25 (4):276-82. . PubMed PMID:26310042 .
Search PubMed
  1. Sánchez-Hernández, MC, Montero, J, Rondon, C, Benitez del Castillo, JM, Velázquez, E, Herreras, JM et al.. Consensus document on allergic conjunctivitis (DECA). J Investig Allergol Clin Immunol. 2015;25 (2):94-106. . PubMed PMID:25997302 .
Search PubMed
  1. Fernández, TD, Gómez, E, Doña, I, Campo, P, Rondon, C, Gonzalez, M et al.. Differential Plasma-cell evolution is linked with Dermatophagoides pteronyssinus immunotherapy response. Sci Rep. 2015;5 :14482. doi: 10.1038/srep14482. PubMed PMID:26416023 PubMed Central PMC4586444.
Search PubMed
  1. Bonadonna, P, Pagani, M, Aberer, W, Bilò, MB, Brockow, K, Oude Elberink, H et al.. Drug hypersensitivity in clonal mast cell disorders: ENDA/EAACI position paper. Allergy. 2015;70 (7):755-63. doi: 10.1111/all.12617. PubMed PMID:25824492 .
Search PubMed
  1. Blanca, M, Thong, BY. Drug hypersensitivity reactions: more basic and clinical research is needed. Curr Opin Allergy Clin Immunol. 2015;15 (4):273-6. doi: 10.1097/ACI.0000000000000182. PubMed PMID:26110675 .
Search PubMed
  1. Agúndez, JA, Mayorga, C, García-Martin, E. Drug metabolism and hypersensitivity reactions to drugs. Curr Opin Allergy Clin Immunol. 2015;15 (4):277-84. doi: 10.1097/ACI.0000000000000174. PubMed PMID:26110676 .
Search PubMed
  1. Gómez, F, Perkins, JR, García-Martín, E, Canto, G, Cornejo-García, JA. Genetic basis of hypersensitivity reactions to nonsteroidal anti-inflammatory drugs. Curr Opin Allergy Clin Immunol. 2015;15 (4):285-93. doi: 10.1097/ACI.0000000000000178. PubMed PMID:26110677 .
Search PubMed
  1. García-Martín, E, Esguevillas, G, Blanca-López, N, García-Menaya, J, Blanca, M, Amo, G et al.. Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis. Pharmacogenet. Genomics. 2015;25 (9):462-4. doi: 10.1097/FPC.0000000000000157. PubMed PMID:26111152 .
Search PubMed
  1. Ayuso, P, Plaza-Serón, Mdel C, Blanca-López, N, Doña, I, Campo, P, Canto, G et al.. Genetic variants in arachidonic acid pathway genes associated with NSAID-exacerbated respiratory disease. Pharmacogenomics. 2015;16 (8):825-39. doi: 10.2217/pgs.15.43. PubMed PMID:26067486 .
Search PubMed
  1. Soler, M, Mesa-Antunez, P, Estevez, MC, Ruiz-Sanchez, AJ, Otte, MA, Sepulveda, B et al.. Highly sensitive dendrimer-based nanoplasmonic biosensor for drug allergy diagnosis. Biosens Bioelectron. 2015;66 :115-23. doi: 10.1016/j.bios.2014.10.081. PubMed PMID:25460891 .
Search PubMed
  1. Guéant, JL, Romano, A, Cornejo-Garcia, JA, Oussalah, A, Chery, C, Blanca-López, N et al.. HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping. J. Allergy Clin. Immunol. 2015;135 (1):253-9. doi: 10.1016/j.jaci.2014.07.047. PubMed PMID:25224099 .
Search PubMed
  1. Ariza, A, Mayorga, C, Fernandez, TD, Barbero, N, Martín-Serrano, A, Pérez-Sala, D et al.. Hypersensitivity reactions to β-lactams: relevance of hapten-protein conjugates. J Investig Allergol Clin Immunol. 2015;25 (1):12-25. . PubMed PMID:25898690 .
Search PubMed
  1. Blanca-López, N, Cornejo-García, JA, Pérez-Alzate, D, Pérez-Sánchez, N, Plaza-Serón, MC, Doña, I et al.. Hypersensitivity Reactions to Nonsteroidal Anti-inflammatory Drugs in Children and Adolescents: Selective Reactions. J Investig Allergol Clin Immunol. 2015;25 (6):385-95. . PubMed PMID:26817135 .
Search PubMed
  1. Blanca-López, N, Cornejo-García, JA, Plaza-Serón, MC, Doña, I, Torres-Jaén, MJ, Canto, G et al.. Hypersensitivity to Nonsteroidal Anti-inflammatory Drugs in Children and Adolescents: Cross-Intolerance Reactions. J Investig Allergol Clin Immunol. 2015;25 (4):259-69. . PubMed PMID:26310040 .
Search PubMed
  1. Campo, P, Villalba, M, Barrionuevo, E, Rondón, C, Salas, M, Galindo, L et al.. Immunologic responses to the major allergen of Olea europaea in local and systemic allergic rhinitis subjects. Clin. Exp. Allergy. 2015;45 (11):1703-12. doi: 10.1111/cea.12600. PubMed PMID:26221871 .
Search PubMed
  1. Garcia-Blanca, A, Aranda, A, Blanca-Lopez, N, Perez, D, Gomez, F, Mayorga, C et al.. Influence of age on IgE response in peanut-allergic children and adolescents from the Mediterranean area. Pediatr Allergy Immunol. 2015;26 (6):497-502. doi: 10.1111/pai.12418. PubMed PMID:26046378 .
Search PubMed
  1. Gómez, E, Fernández, TD, Doña, I, Rondon, C, Campo, P, Gomez, F et al.. Initial immunological changes as predictors for house dust mite immunotherapy response. Clin. Exp. Allergy. 2015;45 (10):1542-53. doi: 10.1111/cea.12578. PubMed PMID:26032922 .
Search PubMed
  1. Fernández, TD, Pearson, JR, Leal, MP, Torres, MJ, Blanca, M, Mayorga, C et al.. Intracellular accumulation and immunological properties of fluorescent gold nanoclusters in human dendritic cells. Biomaterials. 2015;43 :1-12. doi: 10.1016/j.biomaterials.2014.11.045. PubMed PMID:25591956 .
Search PubMed
  1. Lajunen, T, Viitala, L, Kontturi, LS, Laaksonen, T, Liang, H, Vuorimaa-Laukkanen, E et al.. Light induced cytosolic drug delivery from liposomes with gold nanoparticles. J Control Release. 2015;203 :85-98. doi: 10.1016/j.jconrel.2015.02.028. PubMed PMID:25701610 .
Search PubMed
  1. Gómez, F, Rondón, C, Salas, M, Campo, P. Local allergic rhinitis: mechanisms, diagnosis and relevance for occupational rhinitis. Curr Opin Allergy Clin Immunol. 2015;15 (2):111-6. doi: 10.1097/ACI.0000000000000150. PubMed PMID:25961385 .
Search PubMed
  1. Campo, P, Rondón, C, Gould, HJ, Barrionuevo, E, Gevaert, P, Blanca, M et al.. Local IgE in non-allergic rhinitis. Clin. Exp. Allergy. 2015;45 (5):872-881. doi: 10.1111/cea.12476. PubMed PMID:25495772 .
Search PubMed
  1. Le Guével, X, Perez Perrino, M, Fernández, TD, Palomares, F, Torres, MJ, Blanca, M et al.. Multivalent Glycosylation of Fluorescent Gold Nanoclusters Promotes Increased Human Dendritic Cell Targeting via Multiple Endocytic Pathways. ACS Appl Mater Interfaces. 2015;7 (37):20945-56. doi: 10.1021/acsami.5b06541. PubMed PMID:26329370 .
Search PubMed
  1. Agúndez, JA, Blanca, M, Cornejo-García, JA, García-Martín, E. Pharmacogenomics of cyclooxygenases. Pharmacogenomics. 2015;16 (5):501-22. doi: 10.2217/pgs.15.6. PubMed PMID:25916522 .
Search PubMed
  1. Papadopoulos, NG, Bernstein, JA, Demoly, P, Dykewicz, M, Fokkens, W, Hellings, PW et al.. Phenotypes and endotypes of rhinitis and their impact on management: a PRACTALL report. Allergy. 2015;70 (5):474-94. doi: 10.1111/all.12573. PubMed PMID:25620381 .
Search PubMed
  1. Montañez, MI, Najera, F, Mayorga, C, Ruiz-Sanchez, AJ, Vida, Y, Collado, D et al.. Recognition of multiepitope dendrimeric antigens by human immunoglobulin E. Nanomedicine. 2015;11 (3):579-88. doi: 10.1016/j.nano.2015.01.006. PubMed PMID:25661921 .
Search PubMed
  1. Blanca-Lopez, N, Perez-Alzate, D, Ruano, F, Garcimartin, M, de la Torre, V, Mayorga, C et al.. Selective immediate responders to amoxicillin and clavulanic acid tolerate penicillin derivative administration after confirming the diagnosis. Allergy. 2015;70 (8):1013-9. doi: 10.1111/all.12636. PubMed PMID:25913298 .
Search PubMed
  1. Hoffmann, HJ, Santos, AF, Mayorga, C, Nopp, A, Eberlein, B, Ferrer, M et al.. The clinical utility of basophil activation testing in diagnosis and monitoring of allergic disease. Allergy. 2015;70 (11):1393-405. doi: 10.1111/all.12698. PubMed PMID:26198455 .
Search PubMed
  1. Perkins, JR, Sanak, M, Canto, G, Blanca, M, Cornejo-García, JA. Unravelling adverse reactions to NSAIDs using systems biology. Trends Pharmacol. Sci. 2015;36 (3):172-80. doi: 10.1016/j.tips.2014.12.003. PubMed PMID:25577398 .
Search PubMed

Subscribe

Suscríbete a nuestro Newsletter y recibe en tu correo todas las últimas novedades del Instituto.
Consulta el histórico de Newsletter:

Calle Doctor Miguel Díaz Recio , 28 Málaga 29010

(+34) 951 440 260
Fax: (+34) 951 440 263