Enfermedades Inflamatorias y Autoinmunes

Abatacept in interstitial lung disease associated with rheumatoid arthritis: national multicenter study of 263 patients

Fernández-Díaz C, Castañeda S, Melero-González RB, Ortiz-Sanjuán F, Juan-Mas A, Carrasco-Cubero C, Casafont-Solé I, Olivé A, Rodríguez-Muguruza S, Almodóvar-González R, Castellanos-Moreira R, Rodríguez-García SC, Aguilera-Cros C, Villa I, Ordóñez-Palau S, Raya-Alvarez E, Morales-Garrido P, Ojeda-García C, Moreno-Ramos MJ, Bonilla Hernán MG, Hernández Rodríguez I, López-Corbeto M, Andreu JL, Jiménez de Aberásturi JRD, Ruibal-Escribano A, Expósito-Molinero R, Pérez-Sandoval T, López-Robles AM, Carreira-Delgado P, Mena-Vázquez N, Urruticoechea-Arana A, Peralta-Ginés C, Arboleya-Rodríguez L, Narváez García FJ, Palma-Sánchez D, Cervantes Pérez EC, Maiz-Alonso O, Alvarez-Rivas MN, Fernández-Melón J, Vela Casasempere P, Cabezas-Rodríguez I, Castellvi-Barranco I, González-Montagut C, Blanco-Madrigal J, Del Val-Del Amo N, Fito MC, Rodríguez-Gómez M, Salgado-Pérez E, García-Magallón B, Hidalgo-Calleja C, López-Sánchez R, Fernández-Aguado S, Fernández-López JC, Castro-Oreiro S, Serrano-García I, García-Valle A, Romero-Yuste S, Expósito-Pérez L, Pérez-Albadalejo L, García-Aparicio A, Quillis-Marti N, Bernal-Vidal JA, Loricera-García J, Hernández JL, González-Gay MA, Blanco R
Rheumatology (Oxford) 2020 Dec 1;59(12):3906-3916

Antiviral, Immunomodulatory and Antiproliferative Activities of Recombinant Soluble IFNAR2 without IFN-ß Mediation

Hurtado-Guerrero I, Hernáez B, Pinto-Medel MJ, Calonge E, Rodriguez-Bada JL, Urbaneja P, Alonso A, Mena-Vázquez N, Aliaga P, Issazadeh-Navikas S, Pavia J, Leyva L, Alcamí J, Alcamí A, Fernández Ó, Oliver-Martos B
J Clin Med 2020 Mar 31;9(4):959

Expansion of Rare and Harmful Lineages is Associated with Established Rheumatoid Arthritis

Mena-Vázquez N, Ruiz-Limón P, Moreno-Indias I, Manrique-Arija S, Tinahones FJ, Fernández-Nebro A
J Clin Med 2020 Apr 7;9(4):1044

Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry

Mena-Vázquez N, Fernández-Nebro A, Pego-Reigosa JM, Galindo M, Melissa-Anzola A, Uriarte-Isacelay E, Olivé-Marqués A, Aurrecoechea E, Freire M, Tomero E, García-Villanueva MJ, Stoye C, Salas-Heredia E, Bernal-Vidal JA, Salgado E, Blanco R, Javier Novoa F, Ibáñez-Barcelo M, Torrente-Segarra V, Narvaez J, Calvet J, Moriano Morales C, Ramon Vazquez-Rodriguez T, Garcia de la Peña P, Bohórquez C, Andreu-Sánchez JL, Cobo-Ibañez T, Bonilla G, Lozano-Rivas N, Montilla C, Toyos FJ, De la Fuente JLM, Expósito L, Ruiz-Lucea ME, Vals E, Manero-Ruiz J, Bernal-Vidal JA, Rua-Figueroa I
Rheumatology (Oxford) 2020 Aug 1;59(8):2043-2051

Postprandial Apolipoprotein B48 is Associated with Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis

Mena-Vázquez N, Rojas-Gimenez M, Jimenez Nuñez FG, Manrique-Arija S, Rioja J, Ruiz-Limón P, Ureña I, Castro-Cabezas M, Valdivielso P, Fernández-Nebro A
J Clin Med 2020 Aug 2;9(8):2483

Association of apolipoprotein B/apolipoprotein A1 ratio and cardiovascular events in rheumatoid arthritis: results of the CARMA study

Zegarra-Mondragón S, López-González R, Martín-Martínez MA, García-Gómez C, Sánchez-Alonso F, González-Juanatey C, Manrique Arija S, Bonilla Hernán G, Martínez Pardo S, Ruibal Escribano A, Pagán García E, Delgado Frías E, Rivera Redondo J, Delgado Sánchez M, Rodriguez Cambrón AB, Moreno Ramos MJ, Rodríguez Montero SA, Navío Marco MT, Morcillo Valle M, García González J, Bachiller Corral J, Llorca J, Castañeda S, González-Gay MÁ; CARMA Project Collaborative Group
Clin Exp Rheumatol 2020 Jul-Aug;38(4):662-669

Bacteremia in Systemic Lupus Erythematosus in Patients from a Spanish Registry: Risk Factors, Clinical and Microbiological Characteristics, and Outcomes

Rúa-Figueroa I, López-Longo FJ, Del Campo V, Galindo-Izquierdo M, Uriarte E, Torre-Cisneros J, Vela P, Tomero E, Narváez J, Olivé A, Freire M, Salgado E, Andreu JL, Martínez-Taboada V, Calvo-Alén J, Hernández-Cruz B, Raya E, Quevedo V, Expósito Pérez L, Fernández-Nebro A, Ibañez M, Pascual-Valls È, Rúa-Figueroa D, Naranjo A, Pego-Reigosa JM
J Rheumatol 2020 Feb;47(2):234-240

Hormonal Dependence and Cancer in Systemic Lupus Erythematosus

Cobo-Ibáñez T, Urruticoechea-Arana A, Rúa-Figueroa I, Martín-Martínez MA, Ovalles-Bonilla JG, Galindo M, Calvo-Alén J, Olivé A, Fernández-Nebro A, Menor-Almagro R, Tomero E, Horcada L, Uriarte-Itzazelaia E, Martínez-Taboada VM, Andreu JL, Boteanu A, Narváez J, Bohorquez C, Montilla C, Santos G, Hernández-Cruz B, Vela P, Salgado E, Freire M, Hernández-Beriain JÁ, Díez-Álvarez E, Expósito L, Fernández-Berrizbeitia O, Velloso-Feijoo ML, Ibáñez-Barceló M, Lozano-Rivas N, Bonilla G, Moreno M, Raya E, Quevedo-Vila VE, Vázquez-Rodríguez TR, Ibáñez-Ruan J, Muñoz-Fernández S, Sánchez-Alonso F, Pego-Reigosa JM
Arthritis Care Res (Hoboken) 2020 Feb;72(2):216-224

Response to immunotherapy in anti-IgLON5 disease: A systematic review

Cabezudo-García P, Mena-Vázquez N, Estivill Torrús G, Serrano-Castro P
Acta Neurol Scand 2020 Apr;141(4):263-270

Antiphospholipid syndrome (APS) in patients with systemic lupus erythematosus (SLE) implies a more severe disease with more damage accrual and higher mortality

Riancho-Zarrabeitia L, Martínez-Taboada V, Rúa-Figueroa I, Alonso F, Galindo-Izquierdo M, Ovalles J, Olivé-Marqués A, Fernández-Nebro A, Calvo-Alén J, Menor-Almagro R, Tomero-Muriel E, Uriarte-Isacelaya E, Botenau A, Andres M, Freire-González M, Santos Soler G, Ruiz-Lucea E, Ibáñez-Barceló M, Castellví I, Galisteo C, Quevedo Vila V, Raya E, Narváez-García J, Expósito L, Hernández-Beriaín JA, Horcada L, Aurrecoechea E, Pego-Reigosa JM
Lupus 2020 Oct;29(12):1556-1565

Case fatality of COVID-19 in patients with neurodegenerative dementia

Reyes-Bueno JA, Mena-Vázquez N, Ojea-Ortega T, Gonzalez-Sotomayor MM, Cabezudo-Garcia P, Ciano-Petersen NL, Pons-Pons G, Castro-Sánchez MV, Serrano-Castro PJ
Neurologia (Engl Ed) 2020 Nov-Dec;35(9):639-645

Differences in clinical manifestations and increased severity of systemic lupus erythematosus between two groups of Hispanics: European Caucasians versus Latin American mestizos (data from the RELESSER registry)

Hernández Cruz B, Alonso F, Calvo Alén J, Pego-Reigosa JM, López-Longo FJ, Galindo-Izquierdo M, Olivé A, Tomero E, Horcada L, Uriarte E, Erausquin C, Sánchez-Atrio A, Montilla C, Santos Soler G, Fernández-Nebro A, Blanco R, Rodríguez-Gómez M, Vela P, Freire M, Díez-Álvarez E, Boteanu AL, Narváez J, Martínez Taboada V, Ruiz-Lucea E, Andreu JL, Fernández-Berrizbeitia O, Hernández-Beriain JÁ, Gantes M, Pérez-Venegas JJ, Ibáñez-Barceló M, Pecondón-Español Á, Marras C, Bonilla G, Castellví I, Moreno M, Raya E, Quevedo Vila VE, Vázquez T, Ruán JI, Muñoz S, Rúa-Figueroa Í; RELESSER (Spanish Society of Rheumatology Systemic Lupus Erythematosus register) group
Lupus 2020 Jan;29(1):27-36

Prevalence and factors associated with osteoporosis and fragility fractures in patients with primary Sjögren syndrome

Salman-Monte TC, Sanchez-Piedra C, Fernandez Castro M, Andreu JL, Martinez Taboada V, Olivé A, Rosas J, Menor R, Rodríguez B, Garcia Aparicio A, Lopez Longo FJ, Manrique-Arija S, Garcia Vadillo JA, Gil Barato S, López-González R, Galisteo C, Gonzalez Martin J, Ruiz Lucea E, Erausquin C, Melchor S, Moreira B, Raya E, Pego-Reigosa JM, Cid N, Júdez E, Moriano C, Narváez FJ, Corominas H, Garcia Magallon B, Guillen Astete C, Castellvi I, Bohórquez C, Loricera J, Belzunegui J, Illera Ó, Torrente-Segarra V
Rheumatol Int 2020 Aug;40(8):1259-1265

1. Cabezudo-García, P, Ciano-Petersen, NL, Mena-Vázquez, N, Pons-Pons, G, Castro-Sánchez, MV, Serrano-Castro, PJ et al.. Incidence and case fatality rate of COVID-19 in patients with active epilepsy. Neurology. 2020;95 (10):e1417-e1425. doi: 10.1212/WNL.0000000000010033. PubMed PMID:32554773 .

1. Mena-Vázquez, N, Fernández-Nebro, A, Pego-Reigosa, JM, Galindo, M, Melissa-Anzola, A, Uriarte-Isacelay, E et al.. Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry. Rheumatology (Oxford). 2020;59 (8):2043-2051. doi: 10.1093/rheumatology/kez562. PubMed PMID:31808534 PubMed Central PMC7382602.

1. Mena-Vázquez, N, Ruiz-Limón, P, Moreno-Indias, I, Manrique-Arija, S, Tinahones, FJ, Fernández-Nebro, A et al.. Expansion of Rare and Harmful Lineages is Associated with Established Rheumatoid Arthritis. J Clin Med. 2020;9 (4):. doi: 10.3390/jcm9041044. PubMed PMID:32272752 PubMed Central PMC7230781.

1. Julià, A, González, I, Fernández-Nebro, A, Blanco, F, Rodriguez, L, González, A et al.. A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis. Rheumatology (Oxford). 2016;55 (6):1106-11. doi: 10.1093/rheumatology/kew035. PubMed PMID:26983453 .

1. Aterido, A, Cañete, JD, Tornero, J, Ferrándiz, C, Pinto, JA, Gratacós, J et al.. Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis. Ann Rheum Dis. 2019;78 (3):. doi: 10.1136/annrheumdis-2018-214158. PubMed PMID:30552173 .

1. Rúa-Figueroa, Í, López-Longo, J, Galindo-Izquierdo, M, Calvo-Alén, J, Del Campo, V, Olivé-Marqués, A et al.. Incidence, associated factors and clinical impact of severe infections in a large, multicentric cohort of patients with systemic lupus erythematosus. Semin Arthritis Rheum. 2017;47 (1):38-45. doi: 10.1016/j.semarthrit.2017.01.010. PubMed PMID:28259425 .

1. Calvo-Río, V, Santos-Gómez, M, Calvo, I, González-Fernández, MI, López-Montesinos, B, Mesquida, M et al.. Anti-Interleukin-6 Receptor Tocilizumab for Severe Juvenile Idiopathic Arthritis-Associated Uveitis Refractory to Anti-Tumor Necrosis Factor Therapy: A Multicenter Study of Twenty-Five Patients. Arthritis Rheumatol. 2017;69 (3):668-675. doi: 10.1002/art.39940. PubMed PMID:27696756 .

1. Alonso, A, Julià, A, Vinaixa, M, Domènech, E, Fernández-Nebro, A, Cañete, JD et al.. Urine metabolome profiling of immune-mediated inflammatory diseases. BMC Med. 2016;14 (1):133. doi: 10.1186/s12916-016-0681-8. PubMed PMID:27609333 PubMed Central PMC5016926.

1. Fernández-Gutiérrez, B, Perrotti, PP, Gisbert, JP, Domènech, E, Fernández-Nebro, A, Cañete, JD et al.. Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts. Medicine (Baltimore). 2017;96 (26):e7308. doi: 10.1097/MD.0000000000007308. PubMed PMID:28658137 PubMed Central PMC5500059.

1. Julià, A, Blanco, F, Fernández-Gutierrez, B, González, A, Cañete, JD, Maymó, J et al.. Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome-Wide Association Study. Arthritis Rheumatol. 2016;68 (6):1384-91. doi: 10.1002/art.39591. PubMed PMID:26815016 .

1. Julià, A, Pinto, JA, Gratacós, J, Queiró, R, Ferrándiz, C, Fonseca, E et al.. A deletion at ADAMTS9-MAGI1 locus is associated with psoriatic arthritis risk. Ann Rheum Dis. 2015;74 (10):1875-81. doi: 10.1136/annrheumdis-2014-207190. PubMed PMID:25990289 .

1. Rodríguez-García, V, Ioannou, Y, Fernández-Nebro, A, Isenberg, DA, Giles, IP. Examining the prevalence of non-criteria anti-phospholipid antibodies in patients with anti-phospholipid syndrome: a systematic review. Rheumatology (Oxford). 2015;54 (11):2042-50. doi: 10.1093/rheumatology/kev226. PubMed PMID:26152548 .

1. Fernández-Nebro, A, Rúa-Figueroa, Í, López-Longo, FJ, Galindo-Izquierdo, M, Calvo-Alén, J, Olivé-Marqués, A et al.. Cardiovascular Events in Systemic Lupus Erythematosus: A Nationwide Study in Spain From the RELESSER Registry. Medicine (Baltimore). 2015;94 (29):e1183. doi: 10.1097/MD.0000000000001183. PubMed PMID:26200625 PubMed Central PMC4603000.

1. Aterido, A, Cañete, JD, Tornero, J, Blanco, F, Fernández-Gutierrez, B, Pérez, C et al.. A Combined Transcriptomic and Genomic Analysis Identifies a Gene Signature Associated With the Response to Anti-TNF Therapy in Rheumatoid Arthritis. Front Immunol. 2019;10 :1459. doi: 10.3389/fimmu.2019.01459. PubMed PMID:31312201 PubMed Central PMC6614444.

1. Torices, S, Julia, A, Muñoz, P, Varela, I, Balsa, A, Marsal, S et al.. A functional variant of TLR10 modifies the activity of NFkB and may help predict a worse prognosis in patients with rheumatoid arthritis. Arthritis Res Ther. 2016;18 (1):221. doi: 10.1186/s13075-016-1113-z. PubMed PMID:27716427 PubMed Central PMC5050569.

1. Julià, A, Fernandez-Nebro, A, Blanco, F, Ortiz, A, Cañete, JD, Maymó, J et al.. A genome-wide association study identifies a new locus associated with the response to anti-TNF therapy in rheumatoid arthritis. Pharmacogenomics J. 2016;16 (2):147-50. doi: 10.1038/tpj.2015.31. PubMed PMID:25896534 .

1. Julià, A, González, I, Fernández-Nebro, A, Blanco, F, Rodriguez, L, González, A et al.. A genome-wide association study identifies SLC8A3 as a susceptibility locus for ACPA-positive rheumatoid arthritis. Rheumatology (Oxford). 2016;55 (6):1106-11. doi: 10.1093/rheumatology/kew035. PubMed PMID:26983453 .

1. Fernández-Díaz, C, Loricera, J, Castañeda, S, López-Mejías, R, Ojeda-García, C, Olivé, A et al.. Abatacept in patients with rheumatoid arthritis and interstitial lung disease: A national multicenter study of 63 patients. Semin Arthritis Rheum. 2018;48 (1):22-27. doi: 10.1016/j.semarthrit.2017.12.012. PubMed PMID:29422324 .

1. Mena-Vazquez, N, Manrique-Arija, S, Yunquera-Romero, L, Ureña-Garnica, I, Rojas-Gimenez, M, Domic, C et al.. Adherence of rheumatoid arthritis patients to biologic disease-modifying antirheumatic drugs: a cross-sectional study. Rheumatol Int. 2017;37 (10):1709-1718. doi: 10.1007/s00296-017-3758-6. PubMed PMID:28631046 .

1. Bossini-Castillo, L, Campillo-Davó, D, López-Isac, E, Carmona, FD, Simeon, CP, Carreira, P et al.. An MIF Promoter Polymorphism Is Associated with Susceptibility to Pulmonary Arterial Hypertension in Diffuse Cutaneous Systemic Sclerosis. J Rheumatol. 2017;44 (10):1453-1457. doi: 10.3899/jrheum.161369. PubMed PMID:28668810 .

1. Pego-Reigosa, JM, Rúa-Figueroa, Í, López-Longo, FJ, Galindo-Izquierdo, M, Calvo-Alén, J, Olivé-Marqués, A et al.. Analysis of disease activity and response to treatment in a large Spanish cohort of patients with systemic lupus erythematosus. Lupus. 2015;24 (7):720-9. doi: 10.1177/0961203314563818. PubMed PMID:25516473 .

1. Fernández-Gutiérrez, B, Perrotti, PP, Gisbert, JP, Domènech, E, Fernández-Nebro, A, Cañete, JD et al.. Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts. Medicine (Baltimore). 2017;96 (26):e7308. doi: 10.1097/MD.0000000000007308. PubMed PMID:28658137 PubMed Central PMC5500059.

1. Galindo-Izquierdo, M, Rodriguez-Almaraz, E, Pego-Reigosa, JM, López-Longo, FJ, Calvo-Alén, J, Olivé, A et al.. Characterization of Patients With Lupus Nephritis Included in a Large Cohort From the Spanish Society of Rheumatology Registry of Patients With Systemic Lupus Erythematosus (RELESSER). Medicine (Baltimore). 2016;95 (9):e2891. doi: 10.1097/MD.0000000000002891. PubMed PMID:26945378 PubMed Central PMC4782862.

1. Rúa-Figueroa, I, Fernández Castro, M, Andreu, JL, Sanchez-Piedra, C, Martínez-Taboada, V, Olivé, A et al.. Comorbidities in Patients With Primary Sjögren's Syndrome and Systemic Lupus Erythematosus: A Comparative Registries-Based Study. Arthritis Care Res (Hoboken). 2017;69 (1):38-45. doi: 10.1002/acr.23015. PubMed PMID:27564390 .

1. Cabezudo-García, P, Mena-Vázquez, N, Villagrán-García, M, Serrano-Castro, PJ. Efficacy of antiepileptic drugs in autoimmune epilepsy: A systematic review. Seizure. 2018;59 :72-76. doi: 10.1016/j.seizure.2018.05.004. PubMed PMID:29754014 .

1. Gómez-Moyano, E, Ureña-Garnica, I, Manrique-Arija, S, Perez-Belmonte, LM. Erythematous patches with keratotic annular borders on the glans penis. Cleve Clin J Med. 2017;84 (1):23-24. doi: 10.3949/ccjm.84a.15145. PubMed PMID:28084979 .

1. Ferreiro-Iglesias, A, Montes, A, Perez-Pampin, E, Cañete, JD, Raya, E, Magro-Checa, C et al.. Evaluation of 12 GWAS-drawn SNPs as biomarkers of rheumatoid arthritis response to TNF inhibitors. A potential SNP association with response to etanercept. PLoS One. 2019;14 (2):e0213073. doi: 10.1371/journal.pone.0213073. PubMed PMID:30818333 PubMed Central PMC6395028.

1. Rodríguez-García, V, Ioannou, Y, Fernández-Nebro, A, Isenberg, DA, Giles, IP. Examining the prevalence of non-criteria anti-phospholipid antibodies in patients with anti-phospholipid syndrome: a systematic review. Rheumatology (Oxford). 2015;54 (11):2042-50. doi: 10.1093/rheumatology/kev226. PubMed PMID:26152548 .

1. Leon, L, Redondo, M, Fernández-Nebro, A, Gómez, S, Loza, E, Montoro, M et al.. Expert recommendations on the psychological needs of patients with rheumatoid arthritis. Rheumatol Int. 2018;38 (12):2167-2182. doi: 10.1007/s00296-018-4057-6. PubMed PMID:29808295 .

1. Hernandez, MV, Sanchez-Piedra, C, Garcia-Magallon, B, Cuende, E, Manero, J, Campos-Fernandez, C et al.. Factors associated with long-term retention of treatment with golimumab in a real-world setting: an analysis of the Spanish BIOBADASER registry. Rheumatol Int. 2019;39 (3):509-515. doi: 10.1007/s00296-018-4177-z. PubMed PMID:30353269 .

1. Montes, A, Perez-Pampin, E, Joven, B, Carreira, P, Fernández-Nebro, A, Del Carmen Ordóñez, M et al.. FCGR polymorphisms in the treatment of rheumatoid arthritis with Fc-containing TNF inhibitors. Pharmacogenomics. 2015;16 (4):333-45. doi: 10.2217/pgs.14.175. PubMed PMID:25823782 .

1. Perrotti, PP, Aterido, A, Fernández-Nebro, A, Cañete, JD, Ferrándiz, C, Tornero, J et al.. Genetic variation associated with cardiovascular risk in autoimmune diseases. PLoS One. 2017;12 (10):e0185889. doi: 10.1371/journal.pone.0185889. PubMed PMID:28982122 PubMed Central PMC5628882.

1. Julià, A, López-Longo, FJ, Pérez Venegas, JJ, Bonàs-Guarch, S, Olivé, À, Andreu, JL et al.. Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus. Arthritis Res Ther. 2018;20 (1):100. doi: 10.1186/s13075-018-1604-1. PubMed PMID:29848360 PubMed Central PMC5977506.

1. Aterido, A, Julià, A, Carreira, P, Blanco, R, López-Longo, JJ, Venegas, JJP et al.. Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus. Arthritis Res Ther. 2017;19 (1):138. doi: 10.1186/s13075-017-1345-6. PubMed PMID:28619073 PubMed Central PMC5471877.

1. Rúa-Figueroa, Í, López-Longo, J, Galindo-Izquierdo, M, Calvo-Alén, J, Del Campo, V, Olivé-Marqués, A et al.. Incidence, associated factors and clinical impact of severe infections in a large, multicentric cohort of patients with systemic lupus erythematosus. Semin Arthritis Rheum. 2017;47 (1):38-45. doi: 10.1016/j.semarthrit.2017.01.010. PubMed PMID:28259425 .

1. Manrique-Arija, S, Ureña, I, Valdivielso, P, Rioja, J, Jiménez-Núñez, FG, Irigoyen, MV et al.. Insulin resistance and levels of adipokines in patients with untreated early rheumatoid arthritis. Clin Rheumatol. 2016;35 (1):43-53. doi: 10.1007/s10067-015-3106-8. PubMed PMID:26526677 PubMed Central PMC4710654.

1. Andrades, C, Fuego, C, Manrique-Arija, S, Fernández-Nebro, A. Management of cardiovascular risk in systemic lupus erythematosus: a systematic review. Lupus. 2017;26 (13):1407-1419. doi: 10.1177/0961203317704710. PubMed PMID:28457197 .

1. Bethencourt Baute, JJ, Sanchez-Piedra, C, Ruiz-Montesinos, D, Medrano San Ildefonso, M, Rodriguez-Lozano, C, Perez-Pampin, E et al.. Persistence and adverse events of biological treatment in adult patients with juvenile idiopathic arthritis: results from BIOBADASER. Arthritis Res Ther. 2018;20 (1):227. doi: 10.1186/s13075-018-1728-3. PubMed PMID:30305158 PubMed Central PMC6235210.

1. Narváez, J, Borrell, H, Sánchez-Alonso, F, Rúa-Figueroa, I, López-Longo, FJ, Galindo-Izquierdo, M et al.. Primary respiratory disease in patients with systemic lupus erythematosus: data from the Spanish rheumatology society lupus registry (RELESSER) cohort. Arthritis Res Ther. 2018;20 (1):280. doi: 10.1186/s13075-018-1776-8. PubMed PMID:30567600 PubMed Central PMC6299951.

1. Pego-Reigosa, JM, Lois-Iglesias, A, Rúa-Figueroa, Í, Galindo, M, Calvo-Alén, J, de Uña-Álvarez, J et al.. Relationship between damage clustering and mortality in systemic lupus erythematosus in early and late stages of the disease: cluster analyses in a large cohort from the Spanish Society of Rheumatology Lupus Registry. Rheumatology (Oxford). 2016;55 (7):1243-50. doi: 10.1093/rheumatology/kew049. PubMed PMID:27018057 .

1. Ferreiro-Iglesias, A, Montes, A, Perez-Pampin, E, Cañete, JD, Raya, E, Magro-Checa, C et al.. Replication of PTPRC as genetic biomarker of response to TNF inhibitors in patients with rheumatoid arthritis. Pharmacogenomics J. 2016;16 (2):137-40. doi: 10.1038/tpj.2015.29. PubMed PMID:25896535 .

1. Montes, A, Perez-Pampin, E, Navarro-Sarabia, F, Moreira, V, de la Serna, AR, Magallares, B et al.. Rheumatoid arthritis response to treatment across IgG1 allotype - anti-TNF incompatibility: a case-only study. Arthritis Res Ther. 2015;17 :63. doi: 10.1186/s13075-015-0571-z. PubMed PMID:25885039 PubMed Central PMC4411723.

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