
Grupo Multidisciplinar de Investigación Pediátrica
Lineas de Investigación
01Microbiota: Microbiota en apendicectomizados, microbiota tras dieta cetogénica en epilepsia refractaria, microbiota en inmunodeficiencias, microbiota en pacientes críticos.
02. Diabetes y tecnología .
03. Epidemiología en diabetes
04. Crecimiento
05. Obesidad
06. Autoinmunidad y enfermedad inflamatoria intestinal.
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Otro

Proyectos de Investigación
PIGE-0533-2019. Implantación de un programa de seguimiento telemático para pacientes con Diabetes Melllitus tipo 1 usuarios de montorización Free Style Libre y valoración de su impacto en variables metabólicas, calidad de vida y costes sanitarios.
Consejería de Salud y FamiliasErasmus +
Comisión EuropeaErasmus +
Comisión EuropeaC-0032-2016 Nicolas Monardes 2016 Fernando Cardona Díaz Acciones para el refuerzo con recursos humanos de la actividad investigadora en las Unidades de Gestión Clinica del Servicio Andaluz de Salud 2016. Acción C. Vinculación de investigadores a las UGC del SAS. Programa Nicolás Monardes.
SERVICIO ANDALUZ DE SALUDPI17/01104 Estudio de intervención con probiotico para analizar la relación entre permeabiliad intestinal,la microbiotica, la lipemia postprandial, las vesiculas extracelulares , los miRNA y la inflamación
INSTITUTO DE SALUD CARLOS IIIPI14/00082 Endotoxemia, lipemia posprandial y su relación con la inflamación
INSTITUTO DE SALUD CARLOS IIIPIN-0287-2016 Implantación de un Programa de Telemedicina en la Atención a Pacientes Crónicos Complejos-Pluripatológicos y Subsidiarios de Cuidados Paliativos en Una Unidad de Hospitalización A Domicilio Pediátrica
CONSEJERÍA DE SALUDEstudios Clínicos
CNTO148UCO3003. Estudio fase 3 aleatorizado, abierto, para evaluar la Eficacia, Seguridad y Farmacocinética del tratamiento de Golimumab, un anticuerpo humano monoclonal anti-TNF?, administrado por vía subcutánea en pacientes pediátricos con Colitis Ulcerosa activa de mo
JANSSEN BIOLOGICS B.V.CA40192. ESTUDIO DE FASE I, ABIERTO Y ALEATORIZADO PARA EVALUAR LA FARMACOCINÉTICA, LA FARMACODINAMIA Y LA SEGURIDAD DE ETROLIZUMAB SEGUIDO DE UNA EXTENSIÓN ABIERTA Y UNA VIGILANCIA DE LA SEGURIDAD EN PACIENTES PEDIÁTRICOS DE ENTRE 4 Y MENOS DE 18 AÑOS DE EDAD CON
ROCHE FARMA, S.A.200722. Estudio de seguimiento para evaluar la seguridad y los resultados a largo plazo en lactantes nacidos de madres que participaron en los estudios de tratamiento con retosibán
GLAXOSMITH RESEARCH & DEVELOPMENT LIMITEDWB28183. Ensayo clínico de fase III, aleatorizado, doble ciego y controlado con placebo para determinar la eficacia, la seguridad y la tolerabilidad de Lebrikizumab en pacientes adolescentes con asma no controlada tratados con corticosteroides inhalados y un segun
F. HOFFMANN LA ROCHE LTDD5290C00003. Estudio de fase IIb aleatorizado, doble ciego, controlado con placebo para evaluar la seguridad y la eficacia de MEDI8897, un anticuerpo monoclonal con una semivida prolongada frente al virus respiratorio sincitial, en prematuros sanos
MEDINMUNE LTDALX0171-C201. Estudio aleatorizado, en doble ciego, controlado con placebo y multicéntrico, de búsqueda de dosis de ALX-0171 en lactantes y niños de corta edad hospitalizados por infecciones del tracto respiratorio inferior por el virus respiratorio sincitial.
ABLYNX N.V.HPN-100-021. Estudio abierto, aleatorizado, controlado en grupos paralelos para evaluar la seguridad, la farmacocinética y el control de amonio de RAVICTI® (fenilbutirato de glicerol [GPB]) líquido oral y del fenilbutirato de sodio (NaPBA) en pacientes que padecen tr
HORIZON THERAPEUTICS LLCHEP002. Estudio prospectivo, abierto, multicéntrico, de eficacia y seguridad de varias infusiones de Promethera HepaStem en pacientes pediátricos con Trastornos del Ciclo de la Urea.
PROMETHERA BIOSCIENCES SAGS-US-205-1850. Ensayo aleatorizado y doble ciego de fase IIIb para evaluar la seguridad y la eficacia de 2 regímenes de tratamiento con Aztreonam 75 mg polvo y disolvente para solución para inhalación por nebulizador / Aztreonam solución para inhalación (AZLI) en pacien
GILEAD SCIENCES, INCTR701-122. Estudio de Fase III de Fosfato de Tedizolid durante seis días de I. V. A. oral en comparación con el comparador durante 10 días en sujetos de 12 a < 18 años con IPPBc
CUBIST PHARMACEUTICALS INCPENTA 17. Estrategia para el mantenimiento de la supresión del VIH en niños con elvitegravir + darunavir/ritonavir (PENTA 17).
FONDAZIONE PENTA ONLUSMT-11. Ensayo de fase III, para evaluación de la eficacia y la seguridad de unos comprimidos sublinguales de inmunoterapia frente a ácaros del polvo doméstico, en niños y adolescentes (de 5 a 17 años) con asma alérgica inducida por ácaros del polvo doméstico
ALK-ABELLO A/SPublicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
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- Arístegui Fernández, J, González Pérez-Yarza, E, Mellado Peña, MJ, Rodrigo Gonzalo de Liria, C, Hernández Sampelayo, T, García García, JJ et al.. [Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)]. An Pediatr (Barc). 2019;90 (2):86-93. doi: 10.1016/j.anpedi.2018.06.012. PubMed PMID:30055938 .
- Ramos-Fernández, JM, Hernández-Yuste, A, Gutiérrez-Bedmar, M, Cordón Martínez, AM, Moreno-Pérez, D. Does exposure of pregnant women to epidemic respiratory syncytial virus affect the severity of bronchiolitis?. Enferm Infecc Microbiol Clin. 2019;37 (4):251-255. doi: 10.1016/j.eimc.2018.07.002. PubMed PMID:30100097 .
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- Gartner, S, Mondéjar-López, P, Asensio de la Cruz, Ó, Grupo de Trabajo de Fibrosis Quística de la Sociedad Española de Neumología Pediátrica. [Follow-up protocol of patients with cystic fibrosis diagnosed by newborn screening]. An Pediatr (Barc). 2019;90 (4):251.e1-251.e10. doi: 10.1016/j.anpedi.2018.11.009. PubMed PMID:30598406 .
- Moreno-Pérez, D, Álvarez García, FJ, Álvarez Aldeán, J, Cilleruelo Ortega, MJ, Garcés Sánchez, M, García Sánchez, N et al.. [Immunisation schedule of the Spanish Association of Paediatrics: 2019 recommendations]. An Pediatr (Barc). 2019;90 (1):56.e1-56.e9. doi: 10.1016/j.anpedi.2018.10.006. PubMed PMID:30609975 .
- Cabrera, CM, Sánchez-Godoy, L, Navas-López, VM. Is the double gene dose of DQ2.5 or DQ2.5/DQ2.2 an involved factor in the clinical features of celiac disease?. Scand J Gastroenterol. 2019;54 (8):960-964. doi: 10.1080/00365521.2019.1647283. PubMed PMID:31361165 .
- Prieto, LM, Santiago, B, Del Rosal, T, Carazo, B, Jiménez, AB, Pérez-Gorricho, B et al.. Linezolid-containing Treatment Regimens for Tuberculosis in Children. Pediatr Infect Dis J. 2019;38 (3):263-267. doi: 10.1097/INF.0000000000002093. PubMed PMID:29750764 .
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- Álvarez Aldeán, J, Ares Segura, S, Díaz González, C, Montesdeoca Melián, A, García Sánchez, R, Boix Alonso, H et al.. [Recommendations for vaccination against ROTAvirus in PREMature newborns (ROTAPREM)]. An Pediatr (Barc). 2019;91 (3):205.e1-205.e7. doi: 10.1016/j.anpedi.2019.06.001. PubMed PMID:31288982 .
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- Long, L, He, J, Yang, X. Characteristics, emission sources and health risk assessment of trace elements in size-segregated aerosols during haze and non-haze periods at Ningbo, China. Environ Geochem Health. 2021; :. doi: 10.1007/s10653-020-00757-2. PubMed PMID:33459888 .
- Otal, EH, Kim, ML, Dietrich, S, Takada, R, Nakaya, S, Kimura, M et al.. Open-Source Portable Device for the Determination of Fluoride in Drinking Water. ACS Sens. 2021; :. doi: 10.1021/acssensors.0c02273. PubMed PMID:33415970 .
- Gu, G, Bolten, S, Mendes-Oliveira, G, Zhou, B, Teng, Z, Pearlstein, D et al.. Salmonella inactivation and sponge/microfiber mediated cross-contamination during papaya wash with chlorine or peracetic acid as sanitizer. Food Microbiol. 2021;95 :103677. doi: 10.1016/j.fm.2020.103677. PubMed PMID:33397611 .
- Lu, Q, Xu, Z, Xu, X, Liu, L, Liang, L, Chen, Z et al.. Cadmium exposure as a key risk factor for residents in a world large-scale barite mining district, southwestern China. Chemosphere. 2020;269 :129387. doi: 10.1016/j.chemosphere.2020.129387. PubMed PMID:33387789 .
- Cai, J, Shen, H, Wang, Y, Peng, Y, Tang, S, Zhu, Y et al.. A dual recognition strategy for accurate detection of CTCs based on novel branched PtAuRh trimetallic nanospheres. Biosens Bioelectron. 2021;176 :112893. doi: 10.1016/j.bios.2020.112893. PubMed PMID:33342693 .
- Wang, J, Wang, W, Xiong, J, Li, L, Zhao, B, Sohail, I et al.. A constructed wetland system with aquatic macrophytes for cleaning contaminated runoff/storm water from urban area in Florida. J Environ Manage. 2021;280 :111794. doi: 10.1016/j.jenvman.2020.111794. PubMed PMID:33341472 .
- Mansouri, S, Pajohi-Alamoti, M, Aghajani, N, Bazargani-Gilani, B, Nourian, A. Stability and antibacterial activity of Thymus daenensis L. essential oil nanoemulsion in mayonnaise. J Sci Food Agric. 2020; :. doi: 10.1002/jsfa.11026. PubMed PMID:33336802 .
- Gao, Y, Wang, S, Yin, F, Hu, P, Wang, X, Liu, Y et al.. Enhancing sensitivity of microbial fuel cell sensors for low concentration biodegradable organic matter detection: Regulation of substrate concentration, anode area and external resistance. J Environ Sci (China). 2021;101 :227-235. doi: 10.1016/j.jes.2020.08.020. PubMed PMID:33334518 .
- Georgiev, S, Hirnschall, N, Dana-Fisus, A, Ruiss, M, Hienert, J, Leisser, C et al.. Repeatability of intraoperative Shack-Hartmann wavefront sensing in cataract surgery. J Cataract Refract Surg. 2020; :. doi: 10.1097/j.jcrs.0000000000000550. PubMed PMID:33315741 .
- Montso, PK, Mlambo, V, Ateba, CN. Efficacy of novel phages for control of multi-drug resistant Escherichia coli O177 on artificially contaminated beef and their potential to disrupt biofilm formation. Food Microbiol. 2021;94 :103647. doi: 10.1016/j.fm.2020.103647. PubMed PMID:33279072 .
- Aslam, I, Mumtaz, M, Qadir, A, Jamil, N, Baqar, M, Mahmood, A et al.. Organochlorine pesticides (OCPs) in air-conditioner filter dust of indoor urban setting: Implication for health risk in a developing country. Indoor Air. 2020; :. doi: 10.1111/ina.12772. PubMed PMID:33247439 .
- Mackenzie, IS, Ford, I, Nuki, G, Hallas, J, Hawkey, CJ, Webster, J et al.. Long-term cardiovascular safety of febuxostat compared with allopurinol in patients with gout (FAST): a multicentre, prospective, randomised, open-label, non-inferiority trial. Lancet. 2020;396 (10264):1745-1757. doi: 10.1016/S0140-6736(20)32234-0. PubMed PMID:33181081 .
- Tsunoda, N, Otsuka, T, Takayanagi, K, Shimizu, N, Suzuki, T, Utsuno, Y et al.. The impact of nuclear shape on the emergence of the neutron dripline. Nature. 2020;587 (7832):66-71. doi: 10.1038/s41586-020-2848-x. PubMed PMID:33149291 .
- Rusinaru, D, Bohbot, Y, Djelaili, F, Delpierre, Q, Altes, A, Serbout, S et al.. Normative Reference Values of Cardiac Output by Pulsed-Wave Doppler Echocardiography in Adults. Am J Cardiol. 2021;140 :128-133. doi: 10.1016/j.amjcard.2020.10.046. PubMed PMID:33144167 .
- Dalkıran, B, Fernandes, IPG, David, M, Brett, CMA. Electrochemical synthesis and characterization of poly(thionine)-deep eutectic solvent/carbon nanotube-modified electrodes and application to electrochemical sensing. Mikrochim Acta. 2020;187 (11):609. doi: 10.1007/s00604-020-04588-x. PubMed PMID:33057990 .
- Dey Bhowmik, A, Shaw, P, Mondal, P, Chakraborty, A, Sudarshan, M, Chattopadhyay, A et al.. Calcium and Vitamin D Supplementation Effectively Alleviates Dental and Skeletal Fluorosis and Retain Elemental Homeostasis in Mice. Biol Trace Elem Res. 2020; :. doi: 10.1007/s12011-020-02435-x. PubMed PMID:33057951 .
- Tang, J, Li, Z, Xie, M, Zhang, Y, Long, W, Long, S et al.. Optical fiber bio-sensor for phospholipase using liquid crystal. Biosens Bioelectron. 2020;170 :112547. doi: 10.1016/j.bios.2020.112547. PubMed PMID:33010707 .
- Cao, L, Xiao, H, Fang, C, Zhao, F, Chen, Z. Electrochemical immunosensor based on binary nanoparticles decorated rGO-TEPA as magnetic capture and Au@PtNPs as probe for CEA detection. Mikrochim Acta. 2020;187 (10):584. doi: 10.1007/s00604-020-04559-2. PubMed PMID:32990786 .
- Meng, L, Dai, J, Rong, S, Gao, H, Zhang, Z, Zhang, Y et al.. One-step electrodeposition preparation of polyaniline/f-MWCNTs as electrochemical sensors for detection of 10-hydroxycamptothecine. Biotechnol Appl Biochem. 2020; :. doi: 10.1002/bab.2041. PubMed PMID:32970340 .
- Skröder, H, Pettersson, H, Norlén, F, Gustavsson, P, Rylander, L, Albin, M et al.. Occupational exposure to whole body vibrations and birth outcomes - A nationwide cohort study of Swedish women. Sci Total Environ. 2021;751 :141476. doi: 10.1016/j.scitotenv.2020.141476. PubMed PMID:32871309 .
- Moreno, M, Castillo-Corullón, S, Pérez-Ruiz, E, Luna, MC, Antón-Pacheco, JL, Mondejar-Lopez, P et al.. Spanish multicentre study on morbidity and pathogenicity of tracheal bronchus in children. Pediatr Pulmonol. 2019;54 (10):1610-1616. doi: 10.1002/ppul.24435. PubMed PMID:31328420 .
- Álvarez Casaño, M, Alonso Montejo, MDM, Leiva Gea, I, Jiménez Hinojosa, JM, Santos Mata, MÁ, Macías, F et al.. Study of direct costs of type 1 diabetes mellitus in Andalusian patients aged 2-16 years. Endocrinol Diabetes Nutr. 2019;66 (8):480-486. doi: 10.1016/j.endinu.2019.03.010. PubMed PMID:31122889 .
- Álvarez, F, Froes, F, Rojas, AG, Moreno-Perez, D, Martinón-Torres, F. The challenges of influenza for public health. Future Microbiol. 2019;14 :1429-1436. doi: 10.2217/fmb-2019-0203. PubMed PMID:31498705 .
- Navas-López, VM, Pujol Muncunill, G, Llerena, E, Navalón Rubio, M, Gil-Ortega, D, Varea-Calderón, V et al.. [A real-world study focused on the effectiveness and safety of adalimumab as first-line anti-TNF treatment for pediatric Crohn's disease]. An Pediatr (Barc). 2018;88 (2):89-99. doi: 10.1016/j.anpedi.2017.01.013. PubMed PMID:28434894 .
- Ramos-Fernández, JM, Sánchez-Pérez, M, Sánchez-González, JM, Calvo-Cillán, A, Moreno-Pérez, D. Apnea in infants hospitalized with pertussis: Incidence and gestational smoking association. Pediatr Int. 2018;60 (10):943-947. doi: 10.1111/ped.13668. PubMed PMID:30074664 .
- Ramos-Fernández, JM, Moreno-Pérez, D, Gutiérrez-Bedmar, M, Ramírez-Álvarez, M, Martínez García, Y, Artacho-González, L et al.. [Apnoea in infants with bronchiolitis: Incidence and risk factors for a prediction model]. An Pediatr (Barc). 2018;88 (3):160-166. doi: 10.1016/j.anpedi.2017.03.013. PubMed PMID:28479309 .
- Charbit-Henrion, F, Parlato, M, Hanein, S, Duclaux-Loras, R, Nowak, J, Begue, B et al.. Diagnostic Yield of Next-generation Sequencing in Very Early-onset Inflammatory Bowel Diseases: A Multicentre Study. J Crohns Colitis. 2018;12 (9):1104-1112. doi: 10.1093/ecco-jcc/jjy068. PubMed PMID:29788237 PubMed Central PMC6113703.
- Pintos-Morell, G, Blasco-Alonso, J, Couce, ML, Gutiérrez-Solana, LG, Guillén-Navarro, E, O'Callaghan, M et al.. Elosulfase alfa for mucopolysaccharidosis type IVA: Real-world experience in 7 patients from the Spanish Morquio-A early access program. Mol Genet Metab Rep. 2018;15 :116-120. doi: 10.1016/j.ymgmr.2018.03.009. PubMed PMID:30023300 PubMed Central PMC6047108.
- Oliva, S, Thomson, M, de Ridder, L, Martín-de-Carpi, J, Van Biervliet, S, Braegger, C et al.. Endoscopy in Pediatric Inflammatory Bowel Disease: A Position Paper on Behalf of the Porto IBD Group of the European Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2018;67 (3):414-430. doi: 10.1097/MPG.0000000000002092. PubMed PMID:30130311 .
- Lawley, M, Wu, JW, Navas-López, VM, Huynh, HQ, Carroll, MW, Chen, M et al.. Global Variation in Use of Enteral Nutrition for Pediatric Crohn Disease. J Pediatr Gastroenterol Nutr. 2018;67 (2):e22-e29. doi: 10.1097/MPG.0000000000001946. PubMed PMID:29543696 .
- Leiva-Gea, I, Sánchez-Alcoholado, L, Martín-Tejedor, B, Castellano-Castillo, D, Moreno-Indias, I, Urda-Cardona, A et al.. Gut Microbiota Differs in Composition and Functionality Between Children With Type 1 Diabetes and MODY2 and Healthy Control Subjects: A Case-Control Study. Diabetes Care. 2018;41 (11):2385-2395. doi: 10.2337/dc18-0253. PubMed PMID:30224347 .
- Moreno-Pérez, D, Álvarez García, FJ, Álvarez Aldeán, J, Cilleruelo Ortega, MJ, Garcés Sánchez, M, García Sánchez, N et al.. [Immunisation schedule of the Spanish Association of Paediatrics: 2018 recommendations]. An Pediatr (Barc). 2018;88 (1):53.e1-53.e9. doi: 10.1016/j.anpedi.2017.10.001. PubMed PMID:29301718 .
- Ramos-Fernández, JM, Moreno-Pérez, D, Antúnez-Fernández, C, Milano-Manso, G, Cordón-Martínez, AM, Urda-Cardona, A et al.. [Lower lymphocyte response in severe cases of acute bronchiolitis due to respiratory syncytial virus]. An Pediatr (Barc). 2018;88 (6):315-321. doi: 10.1016/j.anpedi.2017.07.003. PubMed PMID:28818563 .
- Sánchez Yáñez, P, Núñez Cuadros, E, Díaz Cordovés-Rego, G, Vera Casaño, A, Urda Cardona, A. Lupus erythematosus tumidus: Benign disease in children?. Pediatr Int. 2018;60 (2):196-197. doi: 10.1111/ped.13452. PubMed PMID:29473307 .
- Church, PC, Kuint, RC, Ledder, O, Navas-López, VM, Sladek, M, Brückner, A et al.. Magnetic Resonance Enterography Cannot Replace Upper Endoscopy in Pediatric Crohn Disease: An Imagekids Sub-study. J Pediatr Gastroenterol Nutr. 2018;67 (1):53-58. doi: 10.1097/MPG.0000000000001869. PubMed PMID:29287012 .
- Turner, D, Ruemmele, FM, Orlanski-Meyer, E, Griffiths, AM, de Carpi, JM, Bronsky, J et al.. Management of Paediatric Ulcerative Colitis, Part 1: Ambulatory Care-An Evidence-based Guideline From European Crohn's and Colitis Organization and European Society of Paediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2018;67 (2):257-291. doi: 10.1097/MPG.0000000000002035. PubMed PMID:30044357 .
- Turner, D, Ruemmele, FM, Orlanski-Meyer, E, Griffiths, AM, de Carpi, JM, Bronsky, J et al.. Management of Paediatric Ulcerative Colitis, Part 2: Acute Severe Colitis-An Evidence-based Consensus Guideline From the European Crohn's and Colitis Organization and the European Society of Paediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2018;67 (2):292-310. doi: 10.1097/MPG.0000000000002036. PubMed PMID:30044358 .
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- Carrasco-Sanz, A, Leiva-Gea, I, Martin-Alvarez, L, Del Torso, S, van Esso, D, Hadjipanayis, A et al.. Migrant children's health problems, care needs, and inequalities: European primary care paediatricians' perspective. Child Care Health Dev. 2018;44 (2):183-187. doi: 10.1111/cch.12538. PubMed PMID:29159977 .
- Ferreras-Antolín, L, Caro-Aguilera, P, Pérez-Ruíz, E, Moreno-Pérez, D, Pérez-Frías, FJ. Perinatal Tuberculosis: Is It a Forgotten Disease?. Pediatr Infect Dis J. 2018;37 (3):e81-e83. doi: 10.1097/INF.0000000000001830. PubMed PMID:29189657 .
- Ariza Jiménez, AB, Núñez Cuadros, E, Galindo Zavala, R, Núñez Caro, L, Díaz-Cordobés Rego, G, Urda Cardona, A et al.. Recurrent multifocal osteomyelitis in children: Experience in a tertiary care center. Reumatol Clin. ;14 (6):334-338. doi: 10.1016/j.reuma.2017.04.002. PubMed PMID:28528870 .
- Delgado Pecellín, I, Pérez Ruiz, E, Álvarez Ríos, AI, Delgado Pecellín, C, Yahyaoui Macías, R, Carrasco Hernández, L et al.. Results of the Andalusian Cystic Fibrosis Neonatal Screening Program, 5 Years After Implementation. Arch Bronconeumol. 2018;54 (11):551-558. doi: 10.1016/j.arbres.2018.03.013. PubMed PMID:29983195 .
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