Laboratorio de Bioingeniería y Regeneración Tisular (LABRET) (IBIMA TECH)(IBIMA RARE)

Lineas de Investigación

01. Regeneración tisular. Ingeniería tisular esquelética. Osteogénesis y condrogénesis terapéutica.

02. Diseño y producción de biomoléculas y biomateriales para la medicina regenerativa del sistema musculoesquelético.

03. Terapia celular basada en Células madre mesenquimales (MSC).

04. Producción y caracterización del secretoma de las MSC. Posibilidades terapéuticas en patologías inflamatorias e inmunomedidas.



Proyectos de Investigación

Mesenchymal stem cell secretome delivery system based on a microparticulate hybrid dressing for chronic skin wound healing (MICRO-SEC)

ISCIII
. 2019

Secretoma de Células Madre Mesenquimales de Tejido Adiposo Canino (cAD-MSCs) y Desarrollo de su Aplicación Clínica en Medicina Veterinaria (SecMeV)

Junta de Andalucía
. 2019

Alterntive therapies for low bone density diseases through modulation of the celular stress

Junta de Andalucía
. 2019

PI-0332-2016 Implantes Personalizados de Titanio Poroso para Defectos Maxilares Segmentarios: Mejora de la Osteointegración y Reparación Tisular Mediante Ingeniería de Tejidos

CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD 2016

RD16/0011/0022 Red de Terapia Celular – TerCel

INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS) 2016

Publicaciones científicas

  • Todo
  • D1
  • Q1
  • Q2
  • Otro
  1. Ulloa, V, Saldivia, N, Ferrada, L, Salazar, K, Martínez, F, Silva-Alvarez, C et al.. Basal Sodium-Dependent Vitamin C Transporter 2 polarization in choroid plexus explant cells in normal or scorbutic conditions. Sci Rep. 2019;9 (1):14422. doi: 10.1038/s41598-019-50772-2. PubMed PMID:31594969 PubMed Central PMC6783570.
Search PubMed
  1. López-Gambero, AJ, Martínez, F, Salazar, K, Cifuentes, M, Nualart, F. Brain Glucose-Sensing Mechanism and Energy Homeostasis. Mol Neurobiol. 2019;56 (2):769-796. doi: 10.1007/s12035-018-1099-4. PubMed PMID:29796992 .
Search PubMed
  1. Villatoro, AJ, Alcoholado, C, Martín-Astorga, MC, Fernández, V, Cifuentes, M, Becerra, J et al.. Comparative analysis and characterization of soluble factors and exosomes from cultured adipose tissue and bone marrow mesenchymal stem cells in canine species. Vet Immunol Immunopathol. 2019;208 :6-15. doi: 10.1016/j.vetimm.2018.12.003. PubMed PMID:30712794 .
Search PubMed
  1. Neri, E, Muzzi, L, Tucci, E, Cini, M, Barabesi, L, Tommasino, G et al.. Arch replacement with collared elephant trunks: The Siena approach. JTCVS Tech. 2021;6 :13-27. doi: 10.1016/j.xjtc.2020.11.017. PubMed PMID:34318130 PubMed Central PMC8300570.
  2. Mulligan, N, Salama, E, Momper, JD, Capparelli, EV, Stek, A, Chakhtoura, N et al.. Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy. J Clin Pharm Ther. 2021; :. doi: 10.1111/jcpt.13477. PubMed PMID:34254323 .
  3. Madilonga, RT, Edokpayi, JN, Volenzo, ET, Durowoju, OS, Odiyo, JO. Water Quality Assessment and Evaluation of Human Health Risk in Mutangwi River, Limpopo Province, South Africa. Int J Environ Res Public Health. 2021;18 (13):. doi: 10.3390/ijerph18136765. PubMed PMID:34202418 PubMed Central PMC8296923.
  4. Qiao, J, Zhang, Y, Liang, X, Ho, T, Huang, HY, Kim, SH et al.. A randomised controlled trial to clinically validate follitropin delta in its individualised dosing regimen for ovarian stimulation in Asian IVF/ICSI patients. Hum Reprod. 2021; :. doi: 10.1093/humrep/deab155. PubMed PMID:34179971 .
  5. Li, Y, Yuan, X, Sun, B, Li, HC, Chu, HW, Wang, L et al.. Rapid-flow expulsion maneuver in subglottic secretion clearance to prevent ventilator-associated pneumonia: a randomized controlled study. Ann Intensive Care. 2021;11 (1):98. doi: 10.1186/s13613-021-00887-5. PubMed PMID:34165661 PubMed Central PMC8222955.
  6. Singh, P, Mandal, S, Roy, D, Chanda, N. Facile Detection of Blood Creatinine Using Binary Copper-Iron Oxide and rGO-Based Nanocomposite on 3D Printed Ag-Electrode under POC Settings. ACS Biomater Sci Eng. 2021;7 (7):3446-3458. doi: 10.1021/acsbiomaterials.1c00484. PubMed PMID:34142794 .
  7. Ambade, B, Kumar, A, Sahu, LK. Characterization and health risk assessment of particulate bound polycyclic aromatic hydrocarbons (PAHs) in indoor and outdoor atmosphere of Central East India. Environ Sci Pollut Res Int. 2021; :. doi: 10.1007/s11356-021-14606-x. PubMed PMID:34050507 .
  8. Wu, X, Li, Z, Zhu, Y, Wang, J, Yang, S. Ultralight GO-Hybridized CNTs Aerogels with Enhanced Electronic and Mechanical Properties for Piezoresistive Sensors. ACS Appl Mater Interfaces. 2021;13 (22):26352-26361. doi: 10.1021/acsami.1c04080. PubMed PMID:34033482 .
  9. Zeng, H, Li, C, Luo, D, Zhang, J, Ding, Y, Chen, M et al.. Novel phage vB_CtuP_B1 for controlling Cronobacter malonaticus and Cronobacter turicensis in ready-to-eat lettuce and powered infant formula. Food Res Int. 2021;143 :110255. doi: 10.1016/j.foodres.2021.110255. PubMed PMID:33992361 .
  10. Haque, MM, Hossain, N, Jolly, YN, Tareq, SM. Probabilistic health risk assessment of toxic metals in chickens from the largest production areas of Dhaka, Bangladesh. Environ Sci Pollut Res Int. 2021; :. doi: 10.1007/s11356-021-13534-0. PubMed PMID:33982252 .
  11. Shen, M, Xu, H, Liu, S, Zhang, Y, Zhang, N, Zhou, J et al.. Spatial distribution of PM2.5-bound elements in eighteen cities over China: policy implication and health risk assessment. Environ Geochem Health. 2021; :. doi: 10.1007/s10653-021-00913-2. PubMed PMID:33978910 .
  12. Hu, YQ, Wang, Z, Guo, JH, Feng, YJ, Ding, MM, Yan, X et al.. [Emission Concentration and Characteristics of Particulate Matter and Water-Soluble Ions in Exhaust Gas of Typical Combustion Sources with Ultra-Low Emission]. Huan Jing Ke Xue. 2021;42 (5):2159-2168. doi: 10.13227/j.hjkx.202010137. PubMed PMID:33884785 .
  13. Bai, X, Lv, H, Liu, Z, Chen, J, Wang, J, Sun, B et al.. Thin-layered MoS2 nanoflakes vertically grown on SnO2 nanotubes as highly effective room-temperature NO2 gas sensor. J Hazard Mater. 2021;416 :125830. doi: 10.1016/j.jhazmat.2021.125830. PubMed PMID:33865111 .
  14. Song, E, Jeon, MJ, Yoo, HJ, Bae, SJ, Kim, TY, Kim, WB et al.. Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults. Endocrinol Metab (Seoul). 2021;36 (2):365-373. doi: 10.3803/EnM.2020.939. PubMed PMID:33823567 PubMed Central PMC8090475.
  15. Liu, N, Li, Y, Li, Y, Cao, L, Nan, N, Li, C et al.. Tunable NH4F-Assisted Synthesis of 3D Porous In2O3 Microcubes for Outstanding NO2 Gas-Sensing Performance: Fast Equilibrium at High Temperature and Resistant to Humidity at Room Temperature. ACS Appl Mater Interfaces. 2021;13 (12):14355-14364. doi: 10.1021/acsami.0c22987. PubMed PMID:33749237 .
  16. Haque, MM, Niloy, NM, Khirul, MA, Alam, MF, Tareq, SM. Appraisal of probabilistic human health risks of heavy metals in vegetables from industrial, non-industrial and arsenic contaminated areas of Bangladesh. Heliyon. 2021;7 (2):e06309. doi: 10.1016/j.heliyon.2021.e06309. PubMed PMID:33718641 PubMed Central PMC7921508.
  17. Liu, L, Li, D, Deng, W. Stimuli-responsive microgels with fluorescent and SERS activities for water and temperature sensing. Biosens Bioelectron. 2021;180 :113138. doi: 10.1016/j.bios.2021.113138. PubMed PMID:33706159 .
  18. Yao, S, Zhao, C, Shang, M, Li, J, Wang, J. Enzyme-free and label-free detection of Staphylococcus aureus based on target-inhibited fluorescence signal recovery. Food Chem Toxicol. 2021;150 :112071. doi: 10.1016/j.fct.2021.112071. PubMed PMID:33609594 .
  19. Xu, J, Jia, C, Yu, H, Xu, H, Ji, D, Wang, C et al.. Characteristics, sources, and health risks of PM2.5-bound trace elements in representative areas of Northern Zhejiang Province, China. Chemosphere. 2021;272 :129632. doi: 10.1016/j.chemosphere.2021.129632. PubMed PMID:33482520 .
  20. Zhou, Y, Tan, Z, Xue, P, Wang, Y, Li, X, Guan, F et al.. High-throughput, in-depth and estimated absolute quantification of plasma proteome using data-independent acquisition/mass spectrometry ("HIAP-DIA"). Proteomics. 2021;21 (5):e2000264. doi: 10.1002/pmic.202000264. PubMed PMID:33460299 .
Search PubMed
  1. Neri, E, Muzzi, L, Tucci, E, Cini, M, Barabesi, L, Tommasino, G et al.. Arch replacement with collared elephant trunks: The Siena approach. JTCVS Tech. 2021;6 :13-27. doi: 10.1016/j.xjtc.2020.11.017. PubMed PMID:34318130 PubMed Central PMC8300570.
  2. Mulligan, N, Salama, E, Momper, JD, Capparelli, EV, Stek, A, Chakhtoura, N et al.. Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy. J Clin Pharm Ther. 2021; :. doi: 10.1111/jcpt.13477. PubMed PMID:34254323 .
  3. Madilonga, RT, Edokpayi, JN, Volenzo, ET, Durowoju, OS, Odiyo, JO. Water Quality Assessment and Evaluation of Human Health Risk in Mutangwi River, Limpopo Province, South Africa. Int J Environ Res Public Health. 2021;18 (13):. doi: 10.3390/ijerph18136765. PubMed PMID:34202418 PubMed Central PMC8296923.
  4. Qiao, J, Zhang, Y, Liang, X, Ho, T, Huang, HY, Kim, SH et al.. A randomised controlled trial to clinically validate follitropin delta in its individualised dosing regimen for ovarian stimulation in Asian IVF/ICSI patients. Hum Reprod. 2021; :. doi: 10.1093/humrep/deab155. PubMed PMID:34179971 .
  5. Li, Y, Yuan, X, Sun, B, Li, HC, Chu, HW, Wang, L et al.. Rapid-flow expulsion maneuver in subglottic secretion clearance to prevent ventilator-associated pneumonia: a randomized controlled study. Ann Intensive Care. 2021;11 (1):98. doi: 10.1186/s13613-021-00887-5. PubMed PMID:34165661 PubMed Central PMC8222955.
  6. Singh, P, Mandal, S, Roy, D, Chanda, N. Facile Detection of Blood Creatinine Using Binary Copper-Iron Oxide and rGO-Based Nanocomposite on 3D Printed Ag-Electrode under POC Settings. ACS Biomater Sci Eng. 2021;7 (7):3446-3458. doi: 10.1021/acsbiomaterials.1c00484. PubMed PMID:34142794 .
  7. Ambade, B, Kumar, A, Sahu, LK. Characterization and health risk assessment of particulate bound polycyclic aromatic hydrocarbons (PAHs) in indoor and outdoor atmosphere of Central East India. Environ Sci Pollut Res Int. 2021; :. doi: 10.1007/s11356-021-14606-x. PubMed PMID:34050507 .
  8. Wu, X, Li, Z, Zhu, Y, Wang, J, Yang, S. Ultralight GO-Hybridized CNTs Aerogels with Enhanced Electronic and Mechanical Properties for Piezoresistive Sensors. ACS Appl Mater Interfaces. 2021;13 (22):26352-26361. doi: 10.1021/acsami.1c04080. PubMed PMID:34033482 .
  9. Zeng, H, Li, C, Luo, D, Zhang, J, Ding, Y, Chen, M et al.. Novel phage vB_CtuP_B1 for controlling Cronobacter malonaticus and Cronobacter turicensis in ready-to-eat lettuce and powered infant formula. Food Res Int. 2021;143 :110255. doi: 10.1016/j.foodres.2021.110255. PubMed PMID:33992361 .
  10. Haque, MM, Hossain, N, Jolly, YN, Tareq, SM. Probabilistic health risk assessment of toxic metals in chickens from the largest production areas of Dhaka, Bangladesh. Environ Sci Pollut Res Int. 2021; :. doi: 10.1007/s11356-021-13534-0. PubMed PMID:33982252 .
  11. Shen, M, Xu, H, Liu, S, Zhang, Y, Zhang, N, Zhou, J et al.. Spatial distribution of PM2.5-bound elements in eighteen cities over China: policy implication and health risk assessment. Environ Geochem Health. 2021; :. doi: 10.1007/s10653-021-00913-2. PubMed PMID:33978910 .
  12. Hu, YQ, Wang, Z, Guo, JH, Feng, YJ, Ding, MM, Yan, X et al.. [Emission Concentration and Characteristics of Particulate Matter and Water-Soluble Ions in Exhaust Gas of Typical Combustion Sources with Ultra-Low Emission]. Huan Jing Ke Xue. 2021;42 (5):2159-2168. doi: 10.13227/j.hjkx.202010137. PubMed PMID:33884785 .
  13. Bai, X, Lv, H, Liu, Z, Chen, J, Wang, J, Sun, B et al.. Thin-layered MoS2 nanoflakes vertically grown on SnO2 nanotubes as highly effective room-temperature NO2 gas sensor. J Hazard Mater. 2021;416 :125830. doi: 10.1016/j.jhazmat.2021.125830. PubMed PMID:33865111 .
  14. Song, E, Jeon, MJ, Yoo, HJ, Bae, SJ, Kim, TY, Kim, WB et al.. Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults. Endocrinol Metab (Seoul). 2021;36 (2):365-373. doi: 10.3803/EnM.2020.939. PubMed PMID:33823567 PubMed Central PMC8090475.
  15. Liu, N, Li, Y, Li, Y, Cao, L, Nan, N, Li, C et al.. Tunable NH4F-Assisted Synthesis of 3D Porous In2O3 Microcubes for Outstanding NO2 Gas-Sensing Performance: Fast Equilibrium at High Temperature and Resistant to Humidity at Room Temperature. ACS Appl Mater Interfaces. 2021;13 (12):14355-14364. doi: 10.1021/acsami.0c22987. PubMed PMID:33749237 .
  16. Haque, MM, Niloy, NM, Khirul, MA, Alam, MF, Tareq, SM. Appraisal of probabilistic human health risks of heavy metals in vegetables from industrial, non-industrial and arsenic contaminated areas of Bangladesh. Heliyon. 2021;7 (2):e06309. doi: 10.1016/j.heliyon.2021.e06309. PubMed PMID:33718641 PubMed Central PMC7921508.
  17. Liu, L, Li, D, Deng, W. Stimuli-responsive microgels with fluorescent and SERS activities for water and temperature sensing. Biosens Bioelectron. 2021;180 :113138. doi: 10.1016/j.bios.2021.113138. PubMed PMID:33706159 .
  18. Yao, S, Zhao, C, Shang, M, Li, J, Wang, J. Enzyme-free and label-free detection of Staphylococcus aureus based on target-inhibited fluorescence signal recovery. Food Chem Toxicol. 2021;150 :112071. doi: 10.1016/j.fct.2021.112071. PubMed PMID:33609594 .
  19. Xu, J, Jia, C, Yu, H, Xu, H, Ji, D, Wang, C et al.. Characteristics, sources, and health risks of PM2.5-bound trace elements in representative areas of Northern Zhejiang Province, China. Chemosphere. 2021;272 :129632. doi: 10.1016/j.chemosphere.2021.129632. PubMed PMID:33482520 .
  20. Zhou, Y, Tan, Z, Xue, P, Wang, Y, Li, X, Guan, F et al.. High-throughput, in-depth and estimated absolute quantification of plasma proteome using data-independent acquisition/mass spectrometry ("HIAP-DIA"). Proteomics. 2021;21 (5):e2000264. doi: 10.1002/pmic.202000264. PubMed PMID:33460299 .
Search PubMed
  1. Neri, E, Muzzi, L, Tucci, E, Cini, M, Barabesi, L, Tommasino, G et al.. Arch replacement with collared elephant trunks: The Siena approach. JTCVS Tech. 2021;6 :13-27. doi: 10.1016/j.xjtc.2020.11.017. PubMed PMID:34318130 PubMed Central PMC8300570.
  2. Mulligan, N, Salama, E, Momper, JD, Capparelli, EV, Stek, A, Chakhtoura, N et al.. Lopinavir and tenofovir interaction observed in non-pregnant adults altered during pregnancy. J Clin Pharm Ther. 2021; :. doi: 10.1111/jcpt.13477. PubMed PMID:34254323 .
  3. Madilonga, RT, Edokpayi, JN, Volenzo, ET, Durowoju, OS, Odiyo, JO. Water Quality Assessment and Evaluation of Human Health Risk in Mutangwi River, Limpopo Province, South Africa. Int J Environ Res Public Health. 2021;18 (13):. doi: 10.3390/ijerph18136765. PubMed PMID:34202418 PubMed Central PMC8296923.
  4. Qiao, J, Zhang, Y, Liang, X, Ho, T, Huang, HY, Kim, SH et al.. A randomised controlled trial to clinically validate follitropin delta in its individualised dosing regimen for ovarian stimulation in Asian IVF/ICSI patients. Hum Reprod. 2021; :. doi: 10.1093/humrep/deab155. PubMed PMID:34179971 .
  5. Li, Y, Yuan, X, Sun, B, Li, HC, Chu, HW, Wang, L et al.. Rapid-flow expulsion maneuver in subglottic secretion clearance to prevent ventilator-associated pneumonia: a randomized controlled study. Ann Intensive Care. 2021;11 (1):98. doi: 10.1186/s13613-021-00887-5. PubMed PMID:34165661 PubMed Central PMC8222955.
  6. Singh, P, Mandal, S, Roy, D, Chanda, N. Facile Detection of Blood Creatinine Using Binary Copper-Iron Oxide and rGO-Based Nanocomposite on 3D Printed Ag-Electrode under POC Settings. ACS Biomater Sci Eng. 2021;7 (7):3446-3458. doi: 10.1021/acsbiomaterials.1c00484. PubMed PMID:34142794 .
  7. Ambade, B, Kumar, A, Sahu, LK. Characterization and health risk assessment of particulate bound polycyclic aromatic hydrocarbons (PAHs) in indoor and outdoor atmosphere of Central East India. Environ Sci Pollut Res Int. 2021; :. doi: 10.1007/s11356-021-14606-x. PubMed PMID:34050507 .
  8. Wu, X, Li, Z, Zhu, Y, Wang, J, Yang, S. Ultralight GO-Hybridized CNTs Aerogels with Enhanced Electronic and Mechanical Properties for Piezoresistive Sensors. ACS Appl Mater Interfaces. 2021;13 (22):26352-26361. doi: 10.1021/acsami.1c04080. PubMed PMID:34033482 .
  9. Zeng, H, Li, C, Luo, D, Zhang, J, Ding, Y, Chen, M et al.. Novel phage vB_CtuP_B1 for controlling Cronobacter malonaticus and Cronobacter turicensis in ready-to-eat lettuce and powered infant formula. Food Res Int. 2021;143 :110255. doi: 10.1016/j.foodres.2021.110255. PubMed PMID:33992361 .
  10. Haque, MM, Hossain, N, Jolly, YN, Tareq, SM. Probabilistic health risk assessment of toxic metals in chickens from the largest production areas of Dhaka, Bangladesh. Environ Sci Pollut Res Int. 2021; :. doi: 10.1007/s11356-021-13534-0. PubMed PMID:33982252 .
  11. Shen, M, Xu, H, Liu, S, Zhang, Y, Zhang, N, Zhou, J et al.. Spatial distribution of PM2.5-bound elements in eighteen cities over China: policy implication and health risk assessment. Environ Geochem Health. 2021; :. doi: 10.1007/s10653-021-00913-2. PubMed PMID:33978910 .
  12. Hu, YQ, Wang, Z, Guo, JH, Feng, YJ, Ding, MM, Yan, X et al.. [Emission Concentration and Characteristics of Particulate Matter and Water-Soluble Ions in Exhaust Gas of Typical Combustion Sources with Ultra-Low Emission]. Huan Jing Ke Xue. 2021;42 (5):2159-2168. doi: 10.13227/j.hjkx.202010137. PubMed PMID:33884785 .
  13. Bai, X, Lv, H, Liu, Z, Chen, J, Wang, J, Sun, B et al.. Thin-layered MoS2 nanoflakes vertically grown on SnO2 nanotubes as highly effective room-temperature NO2 gas sensor. J Hazard Mater. 2021;416 :125830. doi: 10.1016/j.jhazmat.2021.125830. PubMed PMID:33865111 .
  14. Song, E, Jeon, MJ, Yoo, HJ, Bae, SJ, Kim, TY, Kim, WB et al.. Gender-Dependent Reference Range of Serum Calcitonin Levels in Healthy Korean Adults. Endocrinol Metab (Seoul). 2021;36 (2):365-373. doi: 10.3803/EnM.2020.939. PubMed PMID:33823567 PubMed Central PMC8090475.
  15. Liu, N, Li, Y, Li, Y, Cao, L, Nan, N, Li, C et al.. Tunable NH4F-Assisted Synthesis of 3D Porous In2O3 Microcubes for Outstanding NO2 Gas-Sensing Performance: Fast Equilibrium at High Temperature and Resistant to Humidity at Room Temperature. ACS Appl Mater Interfaces. 2021;13 (12):14355-14364. doi: 10.1021/acsami.0c22987. PubMed PMID:33749237 .
  16. Haque, MM, Niloy, NM, Khirul, MA, Alam, MF, Tareq, SM. Appraisal of probabilistic human health risks of heavy metals in vegetables from industrial, non-industrial and arsenic contaminated areas of Bangladesh. Heliyon. 2021;7 (2):e06309. doi: 10.1016/j.heliyon.2021.e06309. PubMed PMID:33718641 PubMed Central PMC7921508.
  17. Liu, L, Li, D, Deng, W. Stimuli-responsive microgels with fluorescent and SERS activities for water and temperature sensing. Biosens Bioelectron. 2021;180 :113138. doi: 10.1016/j.bios.2021.113138. PubMed PMID:33706159 .
  18. Yao, S, Zhao, C, Shang, M, Li, J, Wang, J. Enzyme-free and label-free detection of Staphylococcus aureus based on target-inhibited fluorescence signal recovery. Food Chem Toxicol. 2021;150 :112071. doi: 10.1016/j.fct.2021.112071. PubMed PMID:33609594 .
  19. Xu, J, Jia, C, Yu, H, Xu, H, Ji, D, Wang, C et al.. Characteristics, sources, and health risks of PM2.5-bound trace elements in representative areas of Northern Zhejiang Province, China. Chemosphere. 2021;272 :129632. doi: 10.1016/j.chemosphere.2021.129632. PubMed PMID:33482520 .
  20. Zhou, Y, Tan, Z, Xue, P, Wang, Y, Li, X, Guan, F et al.. High-throughput, in-depth and estimated absolute quantification of plasma proteome using data-independent acquisition/mass spectrometry ("HIAP-DIA"). Proteomics. 2021;21 (5):e2000264. doi: 10.1002/pmic.202000264. PubMed PMID:33460299 .
Search PubMed
  1. Perucca Orfei, C, Viganò, M, Pearson, JR, Colombini, A, De Luca, P, Ragni, E et al.. In Vitro Induction of Tendon-Specific Markers in Tendon Cells, Adipose- and Bone Marrow-Derived Stem Cells is Dependent on TGFβ3, BMP-12 and Ascorbic Acid Stimulation. Int J Mol Sci. 2019;20 (1):. doi: 10.3390/ijms20010149. PubMed PMID:30609804 PubMed Central PMC6337430.
Search PubMed
  1. Izquierdo-Barba, I, Santos-Ruiz, L, Becerra, J, Feito, MJ, Fernández-Villa, D, Serrano, MC et al.. Synergistic effect of Si-hydroxyapatite coating and VEGF adsorption on Ti6Al4V-ELI scaffolds for bone regeneration in an osteoporotic bone environment. Acta Biomater. 2019;83 :456-466. doi: 10.1016/j.actbio.2018.11.017. PubMed PMID:30445158 .
Search PubMed
  1. Martínez, F, Cifuentes, M, Tapia, JC, Nualart, F. The median eminence as the hypothalamic area involved in rapid transfer of glucose to the brain: functional and cellular mechanisms. J Mol Med (Berl). 2019;97 (8):1085-1097. doi: 10.1007/s00109-019-01799-5. PubMed PMID:31129757 .
Search PubMed
  1. Villatoro, AJ, Hermida-Prieto, M, Fernández, V, Fariñas, F, Alcoholado, C, Rodríguez-García, MI et al.. Allogeneic adipose-derived mesenchymal stem cell therapy in dogs with refractory atopic dermatitis: clinical efficacy and safety. Vet Rec. 2018;183 (21):654. doi: 10.1136/vr.104867. PubMed PMID:30158120 .
Search PubMed
  1. Romero-Sánchez, LB, Marí-Beffa, M, Carrillo, P, Medina, MÁ, Díaz-Cuenca, A. Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model. Acta Biomater. 2018;68 :272-285. doi: 10.1016/j.actbio.2017.12.032. PubMed PMID:29288822 .
Search PubMed
  1. Casanellas, I, Lagunas, A, Tsintzou, I, Vida, Y, Collado, D, Pérez-Inestrosa, E et al.. Dendrimer-based Uneven Nanopatterns to Locally Control Surface Adhesiveness: A Method to Direct Chondrogenic Differentiation. J Vis Exp. 2018; (131):. doi: 10.3791/56347. PubMed PMID:29443025 PubMed Central PMC5908668.
Search PubMed
  1. Cifuentes, M, Baeza, V, Arrabal, PM, Visser, R, Grondona, JM, Saldivia, N et al.. Expression of a Novel Ciliary Protein, IIIG9, During the Differentiation and Maturation of Ependymal Cells. Mol Neurobiol. 2018;55 (2):1652-1664. doi: 10.1007/s12035-017-0434-5. PubMed PMID:28194645 .
Search PubMed
  1. García-Caballero, M, Quesada, AR, Medina, MA, Marí-Beffa, M. Fishing anti(lymph)angiogenic drugs with zebrafish. Drug Discov Today. 2018;23 (2):366-374. doi: 10.1016/j.drudis.2017.10.018. PubMed PMID:29081356 .
Search PubMed
  1. Guerra-Rebollo, M, Nogueira de Moraes, C, Alcoholado, C, Soler-Botija, C, Sanchez-Cid, L, Vila, OF et al.. Glioblastoma Bystander Cell Therapy: Improvements in Treatment and Insights into the Therapy Mechanisms. Mol Ther Oncolytics. 2018;11 :39-51. doi: 10.1016/j.omto.2018.09.002. PubMed PMID:30364660 PubMed Central PMC6197388.
Search PubMed
  1. Redondo, LM, García, V, Peral, B, Verrier, A, Becerra, J, Sánchez, A et al.. Repair of maxillary cystic bone defects with mesenchymal stem cells seeded on a cross-linked serum scaffold. J Craniomaxillofac Surg. 2018;46 (2):222-229. doi: 10.1016/j.jcms.2017.11.004. PubMed PMID:29229365 .
Search PubMed
  1. Villatoro, AJ, Claros, S, Fernández, V, Alcoholado, C, Fariñas, F, Moreno, A et al.. Safety and efficacy of the mesenchymal stem cell in feline eosinophilic keratitis treatment. BMC Vet Res. 2018;14 (1):116. doi: 10.1186/s12917-018-1413-4. PubMed PMID:29587744 PubMed Central PMC5870249.
Search PubMed
  1. Salazar, K, Martínez, F, Pérez-Martín, M, Cifuentes, M, Trigueros, L, Ferrada, L et al.. SVCT2 Expression and Function in Reactive Astrocytes Is a Common Event in Different Brain Pathologies. Mol Neurobiol. 2018;55 (7):5439-5452. doi: 10.1007/s12035-017-0762-5. PubMed PMID:28942474 .
Search PubMed
  1. Murciano, C, Cazorla-Vázquez, S, Gutiérrez, J, Hijano, JA, Ruiz-Sánchez, J, Mesa-Almagro, L et al.. Widening control of fin inter-rays in zebrafish and inferences about actinopterygian fins. J Anat. 2018;232 (5):783-805. doi: 10.1111/joa.12785. PubMed PMID:29441573 PubMed Central PMC6480674.
Search PubMed
  1. Forman, K, Martínez, F, Cifuentes, M, Bertinat, R, Salazar, K, Nualart, F et al.. Aging Selectively Modulates Vitamin C Transporter Expression Patterns in the Kidney. J Cell Physiol. 2017;232 (9):2418-2426. doi: 10.1002/jcp.25504. PubMed PMID:27463513 .
Search PubMed
  1. Zamora-Navas, P, Estades-Rubio, FJ, Cano, JR, Guerado, E. Floating hip and associated injuries. Injury. 2017;48 Suppl 6 :S75-S80. doi: 10.1016/S0020-1383(17)30798-2. PubMed PMID:29162246 .
Search PubMed
  1. Rico-Llanos, GA, Becerra, J, Visser, R. Insulin-like growth factor-1 (IGF-1) enhances the osteogenic activity of bone morphogenetic protein-6 (BMP-6) in vitro and in vivo, and together have a stronger osteogenic effect than when IGF-1 is combined with BMP-2. J Biomed Mater Res A. 2017;105 (7):1867-1875. doi: 10.1002/jbm.a.36051. PubMed PMID:28256809 .
Search PubMed
  1. Granados-Durán, P, López-Ávalos, MD, Cifuentes, M, Pérez-Martín, M, Fernández-Arjona, MD, Hughes, TR et al.. Microbial Neuraminidase Induces a Moderate and Transient Myelin Vacuolation Independent of Complement System Activation. Front Neurol. 2017;8 :78. doi: 10.3389/fneur.2017.00078. PubMed PMID:28326060 PubMed Central PMC5339270.
Search PubMed
  1. Marí-Beffa, M, Segura-Egea, JJ, Díaz-Cuenca, A. Regenerative Endodontic Procedures: A Perspective from Stem Cell Niche Biology. J Endod. 2017;43 (1):52-62. doi: 10.1016/j.joen.2016.09.011. PubMed PMID:27986102 .
Search PubMed
  1. Villatoro, AJ, Fernández, V, Claros, S, Alcoholado, C, Cifuentes, M, Merayo-Lloves, J et al.. Regenerative Therapies in Dry Eye Disease: From Growth Factors to Cell Therapy. Int J Mol Sci. 2017;18 (11):. doi: 10.3390/ijms18112264. PubMed PMID:29143779 PubMed Central PMC5713234.
Search PubMed
  1. Visser, R, Bodnarova, K, Arrabal, PM, Cifuentes, M, Becerra, J. Combining bone morphogenetic proteins-2 and -6 has additive effects on osteoblastic differentiation in vitro and accelerates bone formation in vivo. J Biomed Mater Res A. 2016;104 (1):178-85. doi: 10.1002/jbm.a.35546. PubMed PMID:26238281 .
Search PubMed
  1. Jara, N, Cifuentes, M, Martínez, F, Salazar, K, Nualart, F. Cytoarchitecture, Proliferative Activity and Neuroblast Migration in the Subventricular Zone and Lateral Ventricle Extension of the Adult Guinea Pig Brain. Stem Cells. 2016;34 (10):2574-2586. doi: 10.1002/stem.2430. PubMed PMID:27299504 .
Search PubMed
  1. Visser, R, Rico-Llanos, GA, Pulkkinen, H, Becerra, J. Peptides for bone tissue engineering. J Control Release. 2016;244 (Pt A):122-135. doi: 10.1016/j.jconrel.2016.10.024. PubMed PMID:27794492 .
Search PubMed
  1. Orgaz, F, Dzika, A, Szycht, O, Amat, D, Barba, F, Becerra, J et al.. Surface nitridation improves bone cell response to melt-derived bioactive silicate/borosilicate glass composite scaffolds. Acta Biomater. 2016;29 :424-434. doi: 10.1016/j.actbio.2015.10.006. PubMed PMID:26441124 .
Search PubMed
  1. Duran, I, Csukasi, F, Taylor, SP, Krakow, D, Becerra, J, Bombarely, A et al.. Collagen duplicate genes of bone and cartilage participate during regeneration of zebrafish fin skeleton. Gene Expr Patterns. ;19 (1-2):60-9. doi: 10.1016/j.gep.2015.07.004. PubMed PMID:26256560 .
Search PubMed
  1. Duran, I, Ruiz-Sánchez, J, Santamaría, JA, Marí-Beffa, M. Holmgren's principle of delamination during fin skeletogenesis. Mech Dev. 2015;135 :16-30. doi: 10.1016/j.mod.2014.11.002. PubMed PMID:25460362 .
Search PubMed
  1. López-Avalos, MD, Fernández-Llebrez Zayas, R, Cifuentes, M, De Andrés, MV, Fernández-Llebrez Del Rey, P, Grondona, JM et al.. Mente Activa® Improves Impaired Spatial Memory in Aging Rats. J Nutr Health Aging. 2015;19 (8):819-27. doi: 10.1007/s12603-015-0546-4. PubMed PMID:26412286 .
Search PubMed
  1. Villatoro, AJ, Fernández, V, Claros, S, Rico-Llanos, GA, Becerra, J, Andrades, JA et al.. Use of adipose-derived mesenchymal stem cells in keratoconjunctivitis sicca in a canine model. Biomed Res Int. 2015;2015 :527926. doi: 10.1155/2015/527926. PubMed PMID:25802852 PubMed Central PMC4352730.
Search PubMed

Subscribe

Suscríbete a nuestro Newsletter y recibe en tu correo todas las últimas novedades del Instituto.
Consulta el histórico de Newsletter:

Calle Doctor Miguel Díaz Recio , 28 Málaga 29010

(+34) 951 440 260
Fax: (+34) 951 440 263