Molecular Bases of Cell Proliferation and Rare Diseases
Lineas de Investigación
01. Angiogenesis and tumour microenvironments: Identification and characterisation of angiogenesis modulators. Metabolism in the tumour microenvironment.
02. Metabolism of biogenic amines and polyamines in health and disease.
03. Bioinformatics and networks: models of interactomes, disease networks, and medicine networks with predictive methods.
04.Bioinformatics workflows for the automisation of genomic analysis. Analysis of transposon element expression in cancer.
05. Applications of the above lines of research to rare diseases.
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Tecnico Laboratorio
- Otro
Proyectos de Investigación
PLAN PROPIO_AREA 5_2020 Área 5. IBIMA Rare: Enfermedades raras
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
.
2020
PID2019-108096RB-C21 Aproximaciones sistémicas basadas en asociaciones fenotipo-genotipo para mejorar el diagnóstico de pacientes con enfermedades raras
Ministerio de Asuntos Económicos y Transformación Digital
.
2020
PID2019-105010RB-I00. ANGIOGENESIS, INFLAMACION Y METABOLISMO COMO DIANAS TERAPEUTICAS DE LA ANGIOGENESIS PATOLOGICA EMPLEANDO ENFOQUES BIOTECNOLOGICOS
Ministerio de Asuntos Económicos y Transformación Digital
.
2020
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
Copper-containing mesoporous bioactive glass promotes angiogenesis in an in vivo zebrafish model
Romero-Sanchez, LB; Mari-Beffa, M; Carrillo, P; Medina, MA; Diaz-Cuenca, A
Acta Biomaterialia 2018
TransFlow: a modular framework for assembling and assessing accurate de novo transcriptomes in non-model organisms
Seoane, P; Espigares, M; Carmona, R; Polonio, A; Quintana, J; Cretazzo, E; Bota, J; Perez-Garcia, A; Alche, JD; Gomez, L; Claros, MG
Bmc Bioinformatics 2018
Mathematical modeling of cancer metabolism
Medina, MA
Critical Reviews In Oncology Hematology 2018
Fishing anti(lymph)angiogenic drugs with zebrafish
Garcia-Caballero, M; Quesada, AR; Medina, MA; Mari-Beffa, M
Drug Discovery Today 2018
Phenotype-loci associations in networks of patients with rare disorders: application to assist in the diagnosis of novel clinical cases
Bueno, A; Rodriguez-Lopez, R; Reyes-Palomares, A; Rojano, E; Corpas, M; Nevado, J; Lapunzina, P; Sanchez-Jimenez, F; Ranea, JAG
European Journal Of Human Genetics 2018
Comparison of the anti-angiogenic potential of hydroxytyrosol and five derivatives
Lopez-Jimenez, A; Gallardo, E; Espartero, JL; Madrona, A; Quesada, AR; Medina, MA
Food & Function 2018
What We Know and What We Need to Know about Aromatic and Cationic Biogenic Amines in the Gastrointestinal Tract
Fernandez-Reina, A; Urdiales, JL; Sanchez-Jimenez, F
Foods 2018
Exploring the Ring-Closing Metathesis for the Construction of the Solomonamide Macrocyclic Core: Identification of Bioactive Precursors
Cheng-Sanchez, I; Carrillo, P; Sanchez-Ruiz, A; Martinez-Poveda, B; Quesada, AR; Medina, MA; Lopez-Romero, JM; Sarabia, F
Journal Of Organic Chemistry 2018
(+)-Aeroplysinin-1 Modulates the Redox Balance of Endothelial Cells
Garcia-Vilas, JA; Martinez-Poveda, B; Quesada, AR; Medina, MA
Marine Drugs 2018
Bioinformatic Prediction of S-Nitrosylation Sites in Large Protein Datasets.
Carmona, Rosario; Claros, M; de Alche, Juan
Methods In Molecular Biology (Clifton, N.J.) 2018
In silico prediction of targets for anti-angiogenesis and their in vitro evaluation confirm the involvement of SOD3 in angiogenesis.
Garcia-Vilas, Javier A; Morilla, Ian; Bueno, Anibal; Martinez-Poveda, Beatriz; Medina, Miguel Angel; Ranea, Juan A G
Oncotarget 2018
Regulatory role of microRNA in mesenteric lymph nodes after &ITSalmonella&IT Typhimurium infection
Herrera-Uribe, J; Zaldivar-Lopez, S; Aguilar, C; Luque, C; Bautista, R; Carvajal, A; Claros, MG; Garrido, JJ
Veterinary Research 2018
Updates on the hepatocyte growth factor/c-Met axis in hepatocellular carcinoma and its therapeutic implications
Garcia-Vilas, JA; Medina, MA
World Journal Of Gastroenterology 2018
Development of genomic tools in a widespread tropical tree, Symphonia globulifera L.f.: a new low-coverage draft genome, SNP and SSR markers
Olsson, S; Seoane-Zonjic, P; Bautista, R; Claros, MG; Gonzalez-Martinez, SC; Scotti, I; Scotti-Saintagne, C; Hardy, OJ; Heuertz, MMolecular Ecology Resources. 2017
Hydroxytyrosol targets extracellular matrix remodeling by endothelial cells and inhibits both ex vivo and in vivo angiogenesis
Garcia-Vilas, JA; Quesada, AR; Medina, MAFood Chemistry. 2017
Identification and Functional Annotation of Genes Differentially Expressed in the Reproductive Tissues of the Olive Tree (Olea europaea L.) through the Generation of Subtractive Libraries
Zafra, A; Carmona, R; Traverso, JA; Hancock, JT; Goldman, MHS; Claros, MG; Hiscock, SJ; Alche, JDFrontiers In Plant Science. 2017
Polyamine-RNA-membrane interactions: From the past to the future in biology
Acosta-Andrade, C; Artetxe, I; Lete, MG; Monasterio, BG; Ruiz-Mirazo, K; Goni, FM; Sanchez-Jimenez, FColloids And Surfaces B-Biointerfaces. 2017
Structural and Functional View of Polypharmacology
Moya-Garcia, A; Adeyelu, T; Kruger, FA; Dawson, NL; Lees, JG; Overington, JP; Orengo, C; Ranea, JAGScientific Reports. 2017
Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases
Garcia-Caballero, M; Paupert, J; Blacher, S; Van de Velde, M; Quesada, AR; Medina, MA; Noel, AJournal Of Hematology & Oncology. 2017
The Natural Antiangiogenic Compound AD0157 Induces Caspase-Dependent Apoptosis in Human Myeloid Leukemia Cells
Garcia-Caballero, M; Martinez-Poveda, B; Medina, MA; Quesada, ARFrontiers In Pharmacology. 2017
The noni anthraquinone damnacanthal is a multi-kinase inhibitor with potent anti-angiogenic effects
Garcia-Vilas, JA; Pino-Angeles, A; Martinez-Poveda, B; Quesada, AR; Medina, MACancer Letters. 2017
Pleiotropic Role of Puupehenones in Biomedical Research
Martinez-Poveda, B; Quesada, AR; Medina, MAMarine Drugs. 2017
Generation of nitric oxide by olive (Olea europaea L.) pollen during in vitro germination and assessment of the S-nitroso- and nitro-proteomes by computational predictive methods
Jimenez-Quesada, MJ; Carmona, R; Lima-Cabello, E; Traverso, JA; Castro, AJ; Claros, MG; Alche, JDNitric Oxide-Biology And Chemistry. 2017
Genomic analysis of the marine fish pathogen Photobacterium damselae subsp piscicida: Insertion sequences proliferation is associated with chromosomal reorganisations and rampant gene decay
Balado, M; Benzekri, H; Labella, AM; Claros, MG; Manchado, M; Borrego, JJ; Osorio, CR; Lemos, MLInfection Genetics And Evolution. 2017
Automated identification of reference genes based on RNA-seq data
Carmona, R; Arroyo, M; Jimenez-Quesada, MJ; Seoane, P; Zafra, A; Larrosa, R; Alche, JD; Claros, MGBiomedical Engineering Online. 2017
Homocysteine pre-treatment increases redox capacity in both endothelial and tumor cells
Diaz-Santiago, E; Rodriguez-Caso, L; Cardenas, C; Serrano, JJ; Quesada, AR; Medina, MARedox Report. 2017
Enlaces
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Parque Tecnol?gico de Andaluc?a (PTA) Campanillas,
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(+34) 951 440 260
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