Lineas de Investigación
Study of the biological bases of behaviour and the physiopathology of highly prevalent degenerative diseases. These include addition disorders (drug abuse), eating disorders (obesity, diabetes, dyslipidaemia), Alzheimer’s disease, anxiety, and depression. Research throughout disease development and in disease models (psychiatric comorbidity).
01. Alcoholic and nonalcoholic fatty liver disease.
02. Metabolic programming during development and growth (obesity, diabetes).
03. Development of new therapeutic chemical entities or new indications for existing drugs.
05 Pharmacological evaluation of foods for special medical purposes (FSMPs).
Miembros del grupo
- Todos
- IR
- Co-IR
- Investigador
- Otro
Proyectos de Investigación
Papel de la señalización lipídica mediada por monoacilgliceroles y ácido lisofosfatídico en la asociación entre trastornos por uso de alcohol y depresión: iIdentificación de biomarcadores.
ISCIII
.
2021
MV19/00060 Papel de las aciletanolamidas y los acilgliceroles en el consumo abusivo de alcohol durante la adolescencia y la vulnerabilidad a desarrollar trastornos por uso de alcohol.
ISCIII
.
2019
PEIBA-2019-040 BIOMARCADORES CIRCULANTES DE COMORBILIODAD NEUROLÓGICA EN EL TRASTORNO POR CONSUMO TEMPRANO DE ALCOHOL Y/O DROGAS ILEGALES: HERRAMIENTA PREDICTIVA DE DETERIORO COGNITIVO Y DEMENCIAS EN POBLACIONES VULNERABLES.
Ministerio de Sanidad, Consumo y Bienestar Social
.
2019
PI19/00343 Estudio de nuevos factores del sistema GH/IGF: análisis de mecanismos moleculares que regulan crecimiento y metabolismo mediane PAPP-A2 y desarrollo de nuevas terapias.
ISCIII
.
2019
CPII19/00031 Contratos Miguel Servet Tipo II 2019
ISCIII
.
2019
EIN2019-103364 – INNOVATIVE DUAL LIGANDS FOR THE TREATMENT OF ALCOHOL USE DISORDERS AND ITS COMPLICATIONS
Agencia Estatal de Investigación
.
2019
DTS19/00125 Evaluación preclínica de ligandos duales para el tratamiento de los trastornos por uso de alcohol
ISCIII
.
2019
PI19/01577 Alcohol, depresión y deterioro cognitivo: Papel de las aciletanolamidas no cannabinoides. IP Fernando Rodriguez de Fonseca
ISCIII
.
2019
PI19/01577 Alcohol, depresión y deterioro cognitivo: Papel de las aciletanolamidas no cannabinoides. IP Fernando Rodriguez de Fonseca
ISCIII
.
2019
Estancia Universidad de Roma-Sapienza
Sapienza University of Roma
.
2019
ERASMUS+: Intestinal Neoplasia
ISCIII
.
2019
FATZHEIMER: High Fat Diet, Microbiota and Neuroinflammation in the Progression of Alzheimer Disease
European Comission (H2020)
EU-LAC Health
2018
Consumo de alcohol durante la adolescencia: Papel del sistema endocannabinoide en el desarrollo de adicción al alcohol y trastornos afectivos y de ansiedad comórbidos.
Ministerio de Sanidad, Servicios Sociales e Igualdad
Plan Nacional sobre Drogas
2018
Papel del ácido lisofosfatídico en el alcoholismo y la cormobilidad psiquiátrica: implicaciones terapéuticas y evaluación de biomarcadores
CONSEJERÍA DE SALUD
: Proyectos de Investigación biomédica y en ciencias de la salud. Consejería de Salud
2016
Early life stress and excessive alcohol consumption in adolescents: Role of the endocannabinoid system in the vulnerability to alcoholism
INSTITUTO DE SALUD CARLOS III
Proyecto de Investigación Miguel Servet Tipo I. Instituto de Salud Carlos III.
2015
Red de Trastornos Adictivos (Red RTA)
INSTITUTO DE SALUD CARLOS III
RETICS. Instituto de Salud Carlos III. Ministerio de Ciencia e Innovación
2013
Implicación del Sistema endocannabinoide en la vulnerabilidad al alcoholismo en adultos tras el consumo abusivo durante la adolescencia
CONSEJERÍA DE SALUD
Consejería de Salud
2013
CD17/00125 Sara Borrell 2017 Victor Echeverry Alzaty.Jefe de Grupo Fernando Rodriguez de Fonseca
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS SARA BORRELL
2017
PI-0140-2018 Estudio traslacional del papel del ácido lisofosfatídico (LPA) en los trastornos por uso de alcohol
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
FI17/00027 Contrato PFIS 2017 Laura Sanchez Marin.Jefe de Grupo: Fernando Rodriguez de Fonseca
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS PFIS: CONTRATOS PREDOCTORALES DE FORMACIÓN EN INVESTIGACIÓN EN SALUD
2017
PI-0139-2018 ESTUDIO DE LA ACTIVACIÓN DEL RECEPTOR PARA GLP1 COMO BASE DEL DESARROLLO DE TERAPIAS COMBINADAS PARA EL TRATAMIENTO DE LA ESTEATOHEPATITIS NO ALCOHÓLICA
CONSEJERÍA DE SALUD
PROYECTOS DE INVESTIGACIÓN EN SALUD
2018
CPII17/00024 Miiguel Servet Tipo II 2017 Juan Suarez Pérez
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONTRATOS MIGUEL SERVET TIPO II
2017
PI16/01374 Obesidad infantil grave de comienzo precoz al diagnóstico y tras pérdida ponderal: Fundamentos metabólicos, hormonales, genéticos, genómicos, metabolómicos y de microbiota
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2016
RC-0003-2018 Acción C Nicolás Monarde F.Rodríguez de Fonseca
SERVICIO ANDALUZ DE SALUD
RENOVACIÓN ACCIÓN C (PROGRAMA NICOLÁS MONARDES) DE LA CONVOCATORIA
2018
PRX18/00608 Estancias de movilidad de profesores e investigadores seniores en centros extranjeros de enseñanza superior e investigación, incluido el Programa Salvador de Madariaga 2018. Investigador: Fernando Antonio Rodríguez de Fonseca
MINISTERIO DE EDUCACIÓN Y FORMACIÓN PROFESIONAL
ESTANCIAS PROGRAMA SALVADOR DE MADARIAGA
2018
RD16/0017/0001 Red de Trastornos Adictivos
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - CONVOCATORIA DE REDES TEMÁTICAS DE INVESTIGACIÓN COOPERATIVA EN SALUD (RETICS)
2016
PND2018/044 BIOMARCADORES CIRCULANTES DE COMORBILIDAD PSIQUIÁTRICA EN EL TRASTORNO POR USO DE DROGAS: COMPARACIÓN CON BIOMARCADORES DE TRASTORNO DEPRESIVO Y TRASTORNO PSICÓTICO
MINISTERIO DE SANIDAD, CONSUMO Y BIENESTAR SOCIAL
PROYECTOS DE INVESTIGACIÓN SOBRE ADICCIONES
2018
RTC-2016-4983-1 Diseño, ingeniería y ensamblaje de línea piloto de nuevos extractos naturales solvent free y validacion in vivo de compuestos bioactivos
MINISTERIO DE ECONOMIA Y EMPRESA
AYUDAS PARA I+D+i RETOS COLABORACIÓN
2016
PI16/01698 Lípidos transmisores derivados del ácido oleico: Estudio traslacional de su papel en los trastornos por uso de alcohol
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD
2016
DTS16/00115 Desarrollo de nuevos conjugados de ácidos grasos para el tratamiento de las esteatohepatitis
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE DESARROLLO TECNOLÓGICO EN SALUD
2016
PSI2015-73156-JIN Incremento de la neurogénesis hipocampal adulta como estrategia terapéutica para las alteraciones conductuales inducidas por cocaína (COCANEUROGNSIS)
MINISTERIO DE ECONOMIA Y EMPRESA
PROYECTOS I+D+i PARA JÓVENES INVESTIGADORES
2015
MS14/00173 Contrato Miguel Servet Tipo I Antonia Mª Serrano Criado
INSTITUTO DE SALUD CARLOS III
CONTRATOS MIGUEL SERVET TIPO I
2014
2017i043 Consumo de alcohol durante la adolescencia: papel del sistema endocannabinoide en el desarrollo de adicción al alcohol y trastornos afectivos y de ansiedad comórbidos
MINISTERIO DE SANIDAD, CONSUMO Y BIENESTAR SOCIAL
PROYECTOS DE INVESTIGACIÓN SOBRE ADICCIONES
2017
PI17/02026 Estudio Traslacional del Papel del Sistema Endocannabinoide en la Amígdala Ampliada en la Ansiedad Asociada a la Dependencia Alcohólica
INSTITUTO DE SALUD CARLOS III
ACCIÓN ESTRATÉGICA EN SALUD - PROYECTOS DE INVESTIGACIÓN EN SALUD (FIS)
2017
Patentes y Tecnologías
Fatty acids amides for the treatment of alcohol use disorder
Rodríguez de Fonseca, Fernando
Decara del Olmo, Juan Manuel
Serrano Criado, Antonia Maria
Alen Fariñas, Francisco
Decara del Olmo, Juan Manuel
Serrano Criado, Antonia Maria
Alen Fariñas, Francisco
Alen Fariñas, Francisco
Drug for the treatment of steatohepatitis
Rodríguez de Fonseca, Fernando
Pavón Morón, Francisco Javier
Decara del Olmo, Juan Manuel
Serrano Criado, Antonia Maria
Pavón Morón, Francisco Javier
Decara del Olmo, Juan Manuel
Serrano Criado, Antonia Maria
Serrano Criado, Antonia Maria
Amidas de ácidos grasos para el tratamiento del trastorno por abuso de alcohol
Rodríguez de Fonseca, Fernando
Decara del Olmo, Juan Manuel
Serrano Criado, Antonia Maria
Alen Fariñas, Francisco
Decara del Olmo, Juan Manuel
Serrano Criado, Antonia Maria
Alen Fariñas, Francisco
Alen Fariñas, Francisco
Castilla Ortega, Estela
Pavón Morón, Francisco Javier
Rodríguez de Fonseca, Fernando
Sánchez Marín, Laura
Serrano Criado, Antonia Maria
Pavón Morón, Francisco Javier
Rodríguez de Fonseca, Fernando
Sánchez Marín, Laura
Serrano Criado, Antonia Maria
Sánchez Marín, Laura
Serrano Criado, Antonia Maria
Pavón Morón, Francisco Javier
Rodríguez de Fonseca, Fernando
Sánchez Marín, Laura
Serrano Criado, Antonia Maria
Castilla Ortega, Estela
Rodríguez de Fonseca, Fernando
Sánchez Marín, Laura
Serrano Criado, Antonia Maria
Castilla Ortega, Estela
Serrano Criado, Antonia Maria
Castilla Ortega, Estela
Fármaco para el tratamiento de la esteatohepatitis
Rodríguez de Fonseca, Fernando
Pavón Morón, Francisco Javier
Serrano Criado, Antonia Maria
Decara del Olmo, Juan Manuel
Pavón Morón, Francisco Javier
Serrano Criado, Antonia Maria
Decara del Olmo, Juan Manuel
Decara del Olmo, Juan Manuel
Publicaciones científicas
- Todo
- D1
- Q1
- Q2
- Otro
Cooperative role of the glucagon-like peptide-1 receptor and 3-adrenergic-mediated signalling on fat mass reduction through the downregulation of PKA/AKT/AMPK signalling in the adipose tissue and muscle of rats
Decara, J; Rivera, P; Arrabal, S; Vargas, A; Serrano, A; Pavon, FJ; Dieguez, C; Nogueiras, R; de Fonseca, FR; Suarez, J
Acta Physiologica 2018
Perinatal free-choice of a high-calorie low-protein diet affects leptin signaling through IRS1 and AMPK dephosphorylation in the hypothalami of female rat offspring in adulthood
Rivera, Patricia; Ramirez-Lopez, Maria T; Vargas, Antonio; Decara, Juan; Vazquez, Mariam; Arco, Rocio; Gomez de Heras, Raquel; Argente, Jesus; Rodriguez de Fonseca, Fernando; Chowen, Julie A; Suarez, Juan…Menos
Acta Physiologica (Oxford, England) 2018
Cannabinoid dependence induces sustained changes in GABA release in the globus pallidus without affecting dopamine release in the dorsal striatum: A dual microdialysis probe study
Moreno, M; Decara, J; Pavon, FJ; Stouffer, DG; Edwards, S; Serrano, A; Suarez, J; Parsons, LH; de Fonseca, FR
Addiction Biology 2018
Cognitive and neurobehavioral benefits of an enriched environment on young adult mice after chronic ethanol consumption during adolescence.
Rico-Barrio I1,2, Peñasco S1,2, Puente N1,2, Ramos A1,2, Fontaine CJ3, Reguero L1,2, Giordano ME4, Buceta I1,2, Terradillos I1,2, Lekunberri L1, Mendizabal-Zubiaga J1,2, Rodríguez de Fonseca F5, Gerrikagoitia I1,2, Elezgarai I1,2, Grandes P1,2,3.
Addiction Biology
Ethanol-induced alterations in endocannabinoids and relevant neurotransmitters in the nucleus accumbens of fatty acid amide hydrolase knockout mice.
Pavón FJ1,2, Serrano A1,2, Stouffer DG1, Polis I1, Roberto M1, Cravatt BF3, Martin-Fardon R1, Rodríguez de Fonseca F2, Parsons LH1.
Addiction Biology
Fatty acid amide hydrolase (FAAH) inactivation confers enhanced sensitivity to nicotine-induced dopamine release in the mouse nucleus accumbens
Pavon, FJ; Serrano, A; Sidhpura, N; Polis, I; Stouffer, D; de Fonseca, FR; Cravatt, BF; Martin-Fardon, R; Parsons, LH
Addiction Biology 2018
Increased plasma oleoylethanolamide and palmitoleoylethanolamide levels correlate with inflammatory changes in alcohol binge drinkers: the case of HMGB1 in women
Anton, M; Rodriguez-Gonzalez, A; Rodriguez-Rojo, IC; Pastor, A; Correas, A; Serrano, A; Ballesta, A; Alen, F; de Heras, RG; de la Torre, R; de Fonseca, FR; Orio, L
Addiction Biology 2018
Larry Parsons: Researcher, mentor, and friend
Frantz, K; Roberto, M; Mason, B; Koob, GF; Volkow, N; de Fonseca, FR
Addiction Biology 2018
Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory.
Ladron de Guevara-Miranda, David; Moreno-Fernandez, Roman Dario; Gil-Rodriguez, Sara; Rosell-Valle, Cristina; Estivill-Torrus, Guillermo; Serrano, Antonia; Pavon, Francisco J; Rodriguez de Fonseca, Fernando; Santin, Luis J; Castilla-Ortega, Estela
Addiction Biology
Red Bull (R) energy drink increases consumption of higher concentrations of alcohol
Roldan, M; Echeverry-Alzate, V; Buhler, KM; Sanchez-Diez, IJ; Calleja-Conde, J; Olmos, P; Boehm, SL; Maldonado, R; de Fonseca, FR; Santiago, C; Gomez-Gallego, F; Gine, E; Lopez-Moreno, JA
Addiction Biology 2018
Special issue honoring the legacy of Loren H. Parsons
Roberto, M; de Fonseca, FR
Addiction Biology 2018
Young alcohol binge drinkers have elevated blood endotoxin, peripheral inflammation and low cortisol levels: neuropsychological correlations in women
Orio, L; Anton, M; Rodriguez-Rojo, IC; Correas, A; Garcia-Bueno, B; Corral, M; de Fonseca, FR; Garcia-Moreno, LM; Maestu, F; Cadaveira, F
Addiction Biology 2018
Patients with alcohol use disorder: initial results from a prospective multicenter registry in the Spanish Network on Addiction Disorders. CohRTA Study
Sanvisens, A; Zuluaga, P; Rivas, I; Rubio, G; Gual, A; Torrens, M; Short, A; Alvarez, FJ; Tor, J; Farre, M; de Fonseca, FR; Muga, R
Adicciones 2018
Inclusion of Alcoholic Associations Into a Public Treatment Programme for Alcoholism Improves Outcomes During the Treatment and Continuing Care Period: A 6-Year Experience
Rubio, G; Marin, M; Arias, F; Lopez-Trabada, JR; Iribarren, M; Alfonso, S; Prieto, R; Blanco, A; Urosa, B; Montes, V; Jurado, R; Jimenez-Arriero, MA; de Fonseca, FR
Alcohol And Alcoholism 2018
Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure
Rivera, P; Fernandez-Arjona, MD; Silva-Pena, D; Blanco, E; Vargas, A; Lopez-Avalos, MD; Grondona, JM; Serrano, A; Pavon, FJ; de Fonseca, FR; Suarez, J
Biochemical Pharmacology 2018
PPAR alpha/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models
Alen, F; Decara, J; Brunori, G; You, ZB; Buhler, KM; Lopez-Moreno, JA; Cippitelli, A; Pavon, FJ; Suarez, J; Gardner, EL; de la Torre, R; Ciccocioppo, R; Serrano, A; de Fonseca, FR
Biochemical Pharmacology 2018
Oleoylethanolamide and Palmitoylethanolamide Protect Cultured Cortical Neurons Against Hypoxia.
Portavella, Manuel; Rodriguez-Espinosa, Nieves; Galeano, Pablo; Blanco, Eduardo; Romero, Juan I; Holubiec, Mariana I; Rodriguez de Fonseca, Fernando; Fernandez-Espejo, Emilio
Cannabis And Cannabinoid Research 2018
Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice
Horiuchi, K; Perez-Cerezales, S; Papasaikas, P; Ramos-Ibeas, P; Lopez-Cardona, AP; Laguna-Barraza, R; Balvis, NF; Pericuesta, E; Fernandez-Gonzalez, R; Planells, B; Viera, A; Suja, JA; Ross, PJ; Alen, F; Orio, L; de Fonseca, FR; Pintado, B; Valcarcel, J; Gutierrez-Adan, A
Cell Reports 2018
Stress, Depression, Resilience and Ageing: A Role for the LPA-LPA(1) Pathway
Roman, MF; Sara, T; Estela, CO; Margarita, PM; Guillermo, ET; Fernando, RD; Javier, SL; Carmen, P
Current Neuropharmacology 2018
Effects of genetic deletion versus pharmacological blockade of the LPA(1) receptor on depression-like behaviour and related brain functional activity
Moreno-Fernandez, RD; Nieto-Quero, A; Gomez-Salas, FJ; Chun, J; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Perez-Martin, M; Pedraza, C
Disease Models & Mechanisms 2018
Octadecylpropyl Sulfamide Reduces Neurodegeneration and Restores the Memory Deficits Induced by Hypoxia-Ischemia in Mice
Kossatz, E; Silva-Pena, D; Suarez, J; de Fonseca, FR; Maldonado, R; Robledo, P
Frontiers In Pharmacology 2018
Higher Impulsivity As a Distinctive Trait of Severe Cocaine Addiction among Individuals Treated for Cocaine or Alcohol Use Disorders
Garcia-Marchena, N; de Guevara-Miranda, DL; Pedraz, M; Araos, PF; Rubio, G; Ruiz, JJ; Pavon, FJ; Serrano, A; Castilla-Ortega, E; Santin, LJ; de Fonseca, FR
Frontiers In Psychiatry 2018
Training memory without aversion: Appetitive hole-board spatial learning increases adult hippocampal neurogenesis
Sampedro-Piquero, P; Moreno-Fernandez, RD; Manas-Padilla, MC; Gil-Rodriguez, S; Gavito, AL; Pavon, FJ; Pedraza, C; Garcia-Fernandez, M; de Guevara-Miranda, DL; Santin, LJ; Castilla-Ortega, E
Neurobiology Of Learning And Memory 2018
Systemic blockade of LPA(1/3) lysophosphatidic acid receptors by ki16425 modulates the effects of ethanol on the brain and behavior
Sanchez-Maran, L; de Guevara-Miranda, DL; Manas-Padilla, MC; Alen, F; Moreno-Fernandez, RD; Diaz-Navarro, C; Perez-del Palacio, J; Garcia-Fernandez, M; Pedraza, C; Pavon, FJ; de Fonseca, FR; Santin, LJ; Serrano, A; Castilla-Ortega, E
Neuropharmacology 2018
Deficient endocannabinoid signaling in the central amygdala contributes to alcohol dependence-related anxiety-like behavior and excessive alcohol intake
Serrano, A; Pavon, FJ; Buczynski, MW; Schlosburg, J; Natividad, LA; Polis, IY; Stouffer, DG; Zorrilla, EP; Roberto, M; Cravatt, BF; Martin-Fardon, R; de Fonseca, FR; Parsons, LH
Neuropsychopharmacology 2018
Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation.
Sampedro-Piquero, Patricia; de Guevara-Miranda, David Ladron; Pavon, Francisco J; Serrano, Antonia; Suarez, Juan; de Fonseca, Fernando Rodriguez; Santin, Luis J; Castilla-Ortega, Estela
Neuroscience And Biobehavioral Reviews 2018
Palmitoylethanolamide attenuates cocaine-induced behavioral sensitization and conditioned place preference in mice
Zambrana-Infantes, E; del Valle, CR; de Guevara-Miranda, DL; Galeano, P; Castilla-Ortega, E; De Fonseca, FR; Blanco, E; Santin, LJ
Pharmacology Biochemistry And Behavior 2018
Adult-onset hypothyroidism increases ethanol consumption.
Echeverry-Alzate, V; Buhler, K M; Calleja-Conde, J; Huertas, E; Maldonado, R; Rodriguez de Fonseca, F; Santiago, C; Gomez-Gallego, F; Santos, A; Gine, E; Lopez-Moreno, J A
Psychopharmacology 2018
Palmitoylethanolamide prevents neuroinflammation, reduces astrogliosis and preserves recognition and spatial memory following induction of neonatal anoxia-ischemia
Holubiec, MI; Romero, JI; Suarez, J; Portavella, M; Fernandez-Espejo, E; Blanco, E; Galeano, P; de Fonseca, FR
Psychopharmacology 2018
Impact of Percutaneous Coronary Revascularization of Severe Coronary Lesions on Secondary Branches.
Silva-Pena, Daniel; Garcia-Marchena, Nuria; Alen, Francisco; Araos, Pedro; Rivera, Patricia; Vargas, Antonio; Garcia-Fernandez, Maria Inmaculada; Martin-Velasco, Ana Isabel; Villanua, Maria Angeles; Castilla-Ortega, Estela; Santin, Luis; Pavon, Francisco Javier; Serrano, Antonia; Rubio, Gabriel; Rodriguez de Fonseca, Fernando; Suarez, Juan
Revista Espanola De Cardiologia (English Ed.) 2018
Inflammatory gene expression in adipose tissue according to diagnosis of anxiety and mood disorders in obese and non-obese subjects
Coin-Araguez, L; Pavon, FJ; Contreras, A; Gentile, AM; Lhamyani, S; De Diego-Otero, Y; Casado, Y; Olivera, WO; Olveira, G; Tinahones, FJ; Costillas, LP; El Bekay, R
Scientific Reports 2018
The adiponectin promoter activator NP-1 induces high levels of circulating TNF alpha and weight loss in obese (fa/fa) Zucker rats
Decara, J; Serrano, A; Pavon, FJ; Rivera, P; Arco, R; Gavito, A; Vargas, A; Navarro, JA; Tovar, R; Lopez-Gambero, AJ; Martinez, A; Suarez, J; de Fonseca, FR; Baixeras, E
Scientific Reports 2018
Alcohol-induced cognitive deficits are associated with decreased circulating levels of the neurotrophin BDNF in humans and rats.
Silva-Pena, Daniel; Garcia-Marchena, Nuria; Alen, Francisco; Araos, Pedro; Rivera, Patricia; Vargas, Antonio; Garcia-Fernandez, Maria Inmaculada; Martin-Velasco, Ana Isabel; Villanua, Maria Angeles; Castilla-Ortega, Estela; Santin, Luis; Pavon, Francisco Javier; Serrano, Antonia; Rubio, Gabriel; Rodriguez de Fonseca, Fernando; Suarez, Juan…Menos
Addiction Biology
A moderate diet restriction during pregnancy alters the levels of endocannabinoids and endocannabinoid-related lipids in the hypothalamus, hippocampus and olfactory bulb of rat offspring in a sex-specific manner
Ramirez-Lopez, MT; Vazquez, M; Lomazzo, E; Hofmann, C; Blanco, RN; Alen, F; Anton, M; Decara, J; Arco, R; Orio, L; Suarez, J; Lutz, B; de Heras, RG; Bindila, L; de Fonseca, FRPlos One. 2017
A Positive Allosteric Modulator of the Serotonin 5-HT2c Receptor for Obesity
Garcia-Carceles, J; Decara, JM; Vazquez-Villa, H; Rodriguez, R; Codesido, E; Cruces, J; Brea, J; Loza, MI; Alen, F; Botta, J; McCormick, PJ; Ballesteros, JA; Benhamu, B; de Fonseca, FR; Lopez-Rodriguez, MLJournal Of Medicinal Chemistry. 2017
Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver
Rivera, P; Pastor, A; Arrabal, S; Decara, J; Vargas, A; Sanchez-Marin, L; Pavon, FJ; Serrano, A; Bautista, D; Boronat, A; de la Torre, R; Baixeras, E; Lucena, MI; de Fonseca, FR; Suarez, JFrontiers In Pharmacology. 2017
Decreased plasma concentrations of BDNF and IGF-1 in abstinent patients with alcohol use disorders
Garcia-Marchena, N; Silva-Pena, D; Martin-Velasco, AI; Villanua, MA; Araos, P; Pedraz, M; Maza-Ouiroga, R; Romero-Sanchiz, P; Rubio, G; Castilla-Ortega, E; Suarez, J; de Fonseca, FR; Serrano, A; Pavon, FJPlos One. 2017
Dopamine D-4 receptor stimulation prevents nigrostriatal dopamine pathway activation by morphine: relevance for drug addiction
Rivera, A; Gago, B; Suarez-Boomgaard, D; Yoshitake, T; Roales-Bujan, R; Valderrama-Carvajal, A; Bilbao, A; Medina-Luque, J; Diaz-Cabiale, Z; Van Craenenbroeck, K; Borroto-Escuela, DO; Kehr, J; de Fonseca, FR; Santin, L; de la Calle, A; Fuxe, KAddiction Biology. 2017
Glutaminase and MMP-9 Downregulation in Cortex and Hippocampus of LPA(1) Receptor Null Mice Correlate with Altered Dendritic Spine Plasticity
Penalver, A; Campos-Sandoval, JA; Blanco, E; Cardona, C; Castilla, L; Martin-Rufian, M; Estivill-Torrus, G; Sanchez-Varo, R; Alonso, FJ; Perez-Hernandez, M; Colado, MI; Gutierrez, A; de Fonseca, FR; Marquez, JFrontiers In Molecular Neuroscience. 2017
Long-lasting memory deficits in mice withdrawn from cocaine are concomitant with neuroadaptations in hippocampal basal activity, GABAergic interneurons and adult neurogenesis
de Guevara-Miranda, DL; Millon, C; Rosell-Valle, C; Perez-Fernandez, M; Missiroli, M; Serrano, A; Pavon, FJ; de Fonseca, FR; Martinez-Losa, M; Alvarez-Dolado, M; Santin, LJ; Castilla-Ortega, EDisease Models & Mechanisms. 2017
maLPA1-null mice as an endophenotype of anxious depression
Moreno-Fernandez, RD; Perez-Martin, M; Castilla-Ortega, E; del Valle, CR; Garcia-Fernandez, MI; Chun, J; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Pedraza, CTranslational Psychiatry. 2017
Oleoylethanolamide prevents neuroimmune HMGB1/TLR4/NF-kB danger signaling in rat frontal cortex and depressive-like behavior induced by ethanol binge administration
Anton, M; Alen, F; de Heras, RG; Serrano, A; Pavon, FJ; Leza, JC; Garcia-Bueno, B; de Fonseca, FR; Orio, LAddiction Biology. 2017
Plasma concentrations of oleoylethanolamide and other acylethanolamides are altered in alcohol-dependent patients: effect of length of abstinence
Garcia-Marchena, N; Pavon, FJ; Pastor, A; Araos, P; Pedraz, M; Romero-Sanchiz, P; Calado, M; Suarez, J; Castilla-Ortega, E; Orio, L; Boronat, A; Torrens, M; Rubio, G; de la Torre, R; de Fonseca, FR; Serrano, AAddiction Biology. 2017
Prevalence of problematic cell phone use in an adult population in Spain as assessed by the Mobile Phone Problem Use Scale (MPPUS)
De-Sola, JA; Talledo, H; de Fonseca, FR AUTOR PETICION DE COPIAS; Rubio, GPlos One. 2017
Text mining and expert curation to develop a database on psychiatric diseases and their genes
Gutierrez-Sacristan, A; Bravo, A; Portero-Tresserra, M; Valverde, O; Armario, A; Blanco-Gandia, MC; Farre, A; Fernandez-Ibarrondo, L; Fonseca, F; Giraldo, J; Leis, A; Mane, A; Mayer, MA; Montagud-Romero, S; Nadal, R; Ortiz, J; Pavon, FJ; Perez, EJ; Rodriguez-Arias, M; Serrano, A; Torrens, M; Warnault, V; Sanz, F; Furlong, LIDatabase-The Journal Of Biological Databases And Curation. 2017
The CB1 receptor is required for the establishment of the hyperlocomotor phenotype in developmentally-induced hypothyroidism in mice
Gine, E; Echeverry-Alzate, V; Lopez-Moreno, JA; de Fonseca, FR; Perez-Castillo, A; Santos, ANeuropharmacology. 2017
The impact of cocaine on adult hippocampal neurogenesis: Potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction disorder.
Castilla-Ortega, Estela; Ladron de Guevara-Miranda, David; Serrano, Antonia; Pavon, Francisco J; Suarez, Juan; Rodriguez de Fonseca, Fernando; Santin, Luis JBiochemical Pharmacology. 2017
Development of a Mobile Phone addiction craving scale and its Validation in a spanish adult Population
De-Sola, J; Talledo, H; Rubio, G; de Fonseca, FRFrontiers In Psychiatry. 2017
Effects of Intermittent Alcohol Exposure on Emotion and Cognition: A Potential Role for the Endogenous Cannabinoid System and Neuroinflammation
Sanchez-Marin, L; Pavon, FJ; Decara, J; Suarez, J; Gavito, A; Castilla-Ortega, E; de Fonseca, FR; Serrano, AFrontiers In Behavioral Neuroscience. 2017
Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGF alpha) as a potential biomarker of consumption and dual diagnosis
Maza-Quiroga, R; Garcia-Marchena, N; Romero-Sanchiz, P; Barrios, V; Pedraz, M; Serrano, A; Nogueira-Arjona, R; Ruiz, JJ; Soria, M; Campos, R; Chowen, JA; Argente, J; Torrens, M; Lopez-Gallardo, M; Marco, EM; de Fonseca, FR; Pavon, FJ; Araos, PPeerj. 2017
Long-Term Effects of Intermittent Adolescent Alcohol Exposure in Male and Female Rats
Marco, EM; Penasco, S; Hernandez, MD; Gil, A; Borcel, E; Moya, M; Gine, E; Lopez-Moreno, JA; Guerri, C; Lopez-Gallardo, M; de Fonseca, FRFrontiers In Behavioral Neuroscience. 2017
Neuronal Damage Induced by Perinatal Asphyxia Is Attenuated by Postinjury Glutaredoxin-2 Administration
Romero, JI; Holubiec, MI; Tornatore, TL; Riviere, S; Hanschmann, EM; Kolliker-Frers, RA; Tau, J; Blanco, E; Galeano, P; de Fonseca, FR; Lillig, CH; Capani, FOxidative Medicine And Cellular Longevity. 2017
Plasma Chemokines in Patients with Alcohol Use Disorders: Association of CCL11 (Eotaxin-1) with Psychiatric Comorbidity
Garcia-Marchena, N; Araos, PF; Barrios, V; Sanchez-Marin, L; Chowen, JA; Pedraz, M; Castilla-Ortega, E; Romero-Sanchiz, P; Ponce, G; Gavito, AL; Decara, J; Silva, D; Torrens, M; Argente, J; Rubio, G; Serrano, A; de Fonseca, FR; Pavon, FJFrontiers In Psychiatry. 2017
Psychological Factors and Alcohol Use in Problematic Mobile Phone Use in the Spanish Population
De-Sola, J; Talledo, H; Rubio, G; de Fonseca, FRFrontiers In Psychiatry. 2017
Acylethanolamides and endocannabinoid signaling system in dorsal striatum of rats exposed to perinatal asphyxia
Holubiec, MI; Romero, JI; Blanco, E; Tornatore, TL; Suarez, J; de Fonseca, FR; Galeano, P; Capani, FNeuroscience Letters. 2017
Differences in the Rates of Drug Polyconsumption and Psychiatric Comorbidity among Patients with Cocaine Use Disorders According to the Mental Health Service
Araos, P; Vergara-Moragues, Esperanza; Gonzalez-Saiz, Francisco; Pedraz, Maria; Garcia-Marchena, Nuria; Romero-Sanchiz, Pablo; Ruiz, Juan Jesus; Campos-Cloute, Rafael; Serrano, Antonia; Pavon, Francisco Javier; Torrens, Marta; Rodriguez De Fonseca, FernandoJournal Of Psychoactive Drugs. 2017
Glutamate and Brain Glutaminases in Drug Addiction
Marquez, J; Campos-Sandoval, JA; Penalver, A; Mates, JM; Segura, JA; Blanco, E; Alonso, FJ; de Fonseca, FRNeurochemical Research. 2017
The neuropeptides Galanin and Galanin(1-15) in depression-like behaviours
Millon, C; Flores-Burgess, A; Narvaez, M; Borroto-Escuela, DO; Gago, B; Santin, L; Castilla-Ortega, E; Narvaez, JA; Fuxe, K; Diaz-Cabiale, ZNeuropeptides. 2017
Psychiatric comorbidity and plasma levels of 2-acyl-glycerols in outpatient treatment alcohol users. Analysis of gender differences
Garcia-Marchena, N; Araos, P; Pavon, FJ; Ponce, G; Pedraz, M; Serrano, A; Arias, F; Romero-Sanchiz, P; Suarez, J; Pastor, A; de la Torre, R; Torrens, M; Rubio, G; de Fonseca, FRAdicciones. 2017
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