PXE: from gene discovery to look for a therapy

  • 19 enero, 2016
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El próximo día a las en el Aula Magna de la Facultad de Medicina se organiza la conferencia perteneciente al ciclo de conferencias de IBIMA titulada “PXE: from gene discovery to look for a therapy”, que será impartida por la Prof. Daniela Quaglino. Confiamos en vuestra participación.


Prof. Daniela Quaglino

  • Professor, General Pathology. Department of Life Sciences. University of Modena and Reggio Emilia (UniMoRe), Modena, Italy

Daniela Quaglino received a degree in Biological Science cum laude at the University of Modena in 1984, and a PhD in Experimental Pathology in 1992 at the University of Bologna (Italy). She has been Visiting Postdoctoral Research Fellow (1988-89) and Visiting Research Associate (1993) at the Department of Pathology, Vanderbilt University, Nashville, USA. As a Faculty member of UniMoRe, she has been Assistant Professor in General Pathology and Oncology (1992-2001), Associate Professor in General Pathology (2001-2013) and, at present, she is Full Professor of General Pathology and Head of the Departtment of Life Sciences.

She is member of several national and International scientific societies, and during the last decade she has also been involved in the activities of PXE Italia Onlus [www.pxeitalia.unimo.it], the Italian organization affiliated with PXE International, which supports patients and their families and promotes the research on PXE. She is coordinator of the PXELab, a laboratory that, in collaboration with LabGen and the Center for Genomic Research at the Department of Life Sciences, is devoted to PXE reasearch and to PXE ultrastructural and biomolecular diagnosis.

Over the last two decades, her research has been mainly focused on the biology and pathology of the extracellular matrix and on the alterations occurring in skin and blood vessels during aging or in acquired as well as in genetic diseases. In particular, she participated in the international task force working on the discovery of the PXE gene, and has been investigating the molecular pathways involved in the pathogenesis of PXE by identifying molecules involved in elastic fiber calcification and by characterizing changes in the behavior and in the protein profile of PXE fibroblasts.

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