Bruker Ascend 400 MHz NMR spectrometer
Service Description
The NMR service is equipped with a High resolution NMR Spectrometers : a 400MHz
NMR spectrometer for routine experiments and a higher filed.
Applications of NMR spectroscopy to chemistry range from structure elucidation of
small molecules to studies of ligand-protein interactions.
NMR spectrometer for routine experiments and a higher filed.
Applications of NMR spectroscopy to chemistry range from structure elucidation of
small molecules to studies of ligand-protein interactions.
Equipment
Bruker Ascend 400 MHz NMR spectrometer
– Ultra ShieldTM Plus 9.4T magnet
– 5 mm BBFO PLUS probe, optimized for X-nuclei direct observation. Broad band in a frequency range between 31P and 15N
– Ultra ShieldTM Plus 9.4T magnet
– 5 mm BBFO PLUS probe, optimized for X-nuclei direct observation. Broad band in a frequency range between 31P and 15N
Applications
– Structure verification and elucidation
– Molecular mobility: determination of conformation in solution
– Determination of enantiomeric excess
– Kinetic and temperature studies of reaction mixtures
– Molecular mobility: determination of conformation in solution
– Determination of enantiomeric excess
– Kinetic and temperature studies of reaction mixtures
Services Offered
• Experimental design advice and project plan consulting. Services Offered
• Acquisition of 1D NMR spectra at 400 MHz (1 H, 13C, 31P, etc.)
• Acquisition of basic 2D experiments: COSY, TOCSY, HSQC, HMBC, J-RES
– Nuclear Overhauser Effect experiments (NOE and ROE), Diffusion experiments (DOSY), selective excitation experiments.