NUCLEAR AND X-RAY IMAGING
PET/SPECT/CT
Service Description
PET/SPECT/CT is a trimodal imaging equipment that combines computed tomography (CT) with positron emission tomography (PET) or single photon emission tomography (SPECT) in the same image.
PET/SPECT is a non-invasive technique for measuring the metabolic activity of the animal body. It detects and analyzes the three-dimensional distribution that a radiopharmaceutical administered through an intravenous injection adopts inside a body.
CT is an X-ray scanning technology that produces images in all three anatomical planes (axial, sagittal, and coronal). These images are combined to create a three-dimensional image of the scanned object.
PET/SPECT/CT allows visualizing in three dimensions and in real time the evolution of diseases such as the formation of tumors or the formation and progression of cardiac and respiratory diseases. Likewise, the effect of different experimental treatments can be monitored and visualized.
- Imaging Modalities: PET, SPECT, CT.
- Coincidence based PET featuring Full Field of View Accuracy which means constant resolution across the entire FOV for consistent quantification.
- Adaptative SPECT FOV from to 25 to 120 mm (in one single bed position) and 4 different collimator types.
- Single compact footprint 90 × 220 cm.
- Fully automated animal handling system .
- Fully Integrated Albira Suite: ACQUIRER: Image Acquisition, RECONSTRUCTOR: Image Reconstruction, MANAGER: Study and Protocol Management, SUPERVISOR: Quality Control.
- Image Analysis Software: PMOD software included.
- Albira small animal CT system
- Dedicated beds for individual rats and mice with anaesthesia.
- MATS bed for simultaneous imaging of up to four mice with anesthesia
- 90 µM resolution and 70 mm diameter Field of View (FOV).
- Energy Range (kVp) 10-50.
- QRM Micro-CT HA Phantom 0, 50, 200, 800,1200 mg HA/cm3 densities.
Applications
- Dentistry and bone regeneration studies
- Contextual/anatomical imaging in conjunction with other modalities
- Bone density analysis
- Implantation studies
- Quantitative 3D tomographic imaging of radiotracers, bone, and soft tissue.
- Nuclear imaging (PET and SPECT): studies of cellular metabolism by glucose (18F-FDG) with applications in oncology, neurology, cardiology, and inflammatory and infectious diseases. In vivo monitoring of biomolecules (antibodies/peptides) and cells. Evaluation of the effect of compounds in longitudinal animal models.
- Computerized tomography image: bone and biomaterial, morphometric, lung studies, etc.
- Molecular labels: optical and/or radioactive labels of biomolecules (antibodies, peptides, microvesicles, etc.)
- In vivo optical imaging: tumor metabolism (genetically modified cells), cell tracking, etc.
- Other services provided by the laboratory are advice regarding the optimal techniques for a specific problem and data post-processing (including quantification, co-registration of modalities, statistical parametric analysis -SPM-, PMOD, etc.).
IRRADIATOR
Service Description
The X-RAD 225 is a compact cabinet X-ray irradiator for higher energy irradiation studies and is ideal for delivering high doses in the biology and material sciences.
- Largest internal x-ray chamber
- Focal irradiation with automated or fixed collimators
- Full screen, real-time specimen viewing
- Motorized turntable and adjustable programmable specimen shelf
- Integrated filter recognition
- Daily automated dose QA
- Imaging capabilities with OptiMAX
Applications
- Bone marrow myeloablation
- Irradiation of in vitro cells or biological samples (blood)
- Study of DNA repair processes
The X-Rad225XL is ideal for large cell cultures and small animal applications. This system can be used to irradiate models in vivo (rats and mice) and in vitro (cell cultures).
Technical staff
FEIJOO CUARESMA, MÓNICA
Técnico de laboratorio
mfeijoo@ibima.eu