Clinical and Translational Research in Cancer
Lines of Research
01.Clinical-translational research in breast, prostate, gynecological, digestive, and germ cell cancers
02.Translational research in the identification of epigenetic/genetic markers in early stages of cancer
03.Research on the use of new diagnostic techniques (liquid biopsy, etc.) and markers
04.Research on the relationship between the microbiota and cancer
05.Research on real-world data real world data
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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A Phase IIIB study to evaluate the useof durvalumab in combination with platinun-bas chemotherpy followed by urvalumab with olaparib as first-line tratment in Patientsw Newly Diagnosed pMMR Advanced or Recurret Endometrial Cancer in Spain.
MARIA JOSE BERMEJO PEREZ – ENSAYO CLINICO CON MEDICAMENTOS – III – APICES SOLUCIONES S.L.
A Phase Ib/III Randomised Study of Capivasertib plus Palbociclib and Fulvestrant versus Placebo plus Palbociclib and Fulvestrant in Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Locally Advanced, Unresectable or Metastatic Breast Cancer (CAPItello-292-D361DC00001)
MARIA EMILIA DOMINGUEZ RECIO – ENSAYO CLINICO CON MEDICAMENTOS – III – ASTRAZENECA AB
A Phase 1, Open-Label, Multicenter Study of INCA32459 in Participants With Select Advanced Malignancies
JAVIER GARCÍA CORBACHO – ENSAYO CLINICO CON MEDICAMENTOS – I – INCYTE CORPORATION
A Phase 1, Multicenter, Open-Label Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Combinations of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Subjects with Locally Advanced or Metastatic Solid Tumors
JAVIER GARCÍA CORBACHO – ENSAYO CLINICO COMERCIAL – I – ABBVIE DEUTSCHLAND GMBH & CON K. G
A phase 1 study of oral Debio 0123 in combination with carboplatin in patients with advanced solid tumors
JAVIER GARCÍA CORBACHO – ENSAYO CLINICO CON MEDICAMENTOS – I – DEBIOPHARM INTERNATIONAL S.A.
A Phase 1 Study of BOS172738 in Patients with Advanced Solid Tumors with RET Gene Alterations including Non Small Cell Lung Cancer (NSCLC) and Medullary Thyroid Cancer (MTC)
LAURA MEDINA RODRÍGUEZ – ENSAYO CLINICO COMERCIAL – I – PRECISION FOR MEDICINE, LLC
2023-12144 Estudio observacional, internacional, retrospectivo de revisión de historiasclínicas, para describir las características, patrones de tratamiento y resultados clínicos en los pacientestratados con selpercatinib dentro de un Programa de Acceso Temprano en España y Portugal (EstudioSELPIBER).
ANDRES MESAS RUIZ – ESTUDIO OBSERVACIONAL CON MEDICAMENTOS – No aplica – LILLY, S.A.
“Ensayo fase III, multicéntrico, aleatorizado, doble ciego, de grupos paralelos, controlado con placebo, para evaluar la eficacia y la seguridad de olaparib frente a placebo como tratamiento adyuvante en pacientes con cáncer de mama HER2 negativo de alto riesgo y mutaciones germinales de BRCA1/2, que han finalizado el tratamiento local y la quimioterapia neoadyuvante o adyuvante”. Estudio OLYMPIA.
ANTONIA MÁRQUEZ ARAGONÉS – ENSAYO CLINICO COMERCIAL – III – FUNDACIÓN GRUPO ESPAÑOL DE INVESTIGACIÓN EN CÁNCER MAMA
Connection between the Gut Microbiome, Systemic Inflammation, Gut Permeability and FOXP3 Expression in Patients with Primary Sjogren’s Syndrome
Cano-Ortiz, A; Laborda-Illanes, A; Plaza-Andrades, I; del Pozo, AM; Cuadrado, AV; de Mora, MRC; Leiva-Gea, I; Sanchez-Alcoholado, L; Queipo-Ortuno, MI – 2020
Phase II Trial of Palbociclib in Recurrent Retinoblastoma-Positive Anaplastic Oligodendroglioma: A Study from the Spanish Group for Research in Neuro-Oncology (GEINO)
Sepulveda-Sanchez, JM; Gil-Gil, M; Alonso-Garcia, M; Salgado, MAV; Vicente, E; Barroso, CM; Sanchez, AR; Duran, G; De Las Penas, R; Munoz-Langa, J; Velasco, G; Hernandez-Lain, A; Hilario, A; Martin, MN; Benavides, M; Oleaga, L; Montenegro, DC; Ruano, Y; Sanchez-Gomez, P; Martin-Soberon, MC; Morales-Llombart, R; Pachon, V; Pineda, E – 2020
Current Options for Third-line and Beyond Treatment of Metastatic Colorectal Cancer. Spanish TTD Group Expert Opinion
Fernandez-Montes, A; Gravalos, C; Pericay, C; Safont, MJ; Benavides, M; EElez, E; Garcia-Alfonso, P; Garcia-Paredes, B; Carrato, A; Aranda, E – 2020
Resistance to Neoadjuvant Treatment in Breast Cancer: Clinicopathological and Molecular Predictors
Chica-Parrado, MR; Godoy-Ortiz, A; Jimenez, B; Ribelles, N; Barragan, I; Alba, E – 2020
EDIL3 promotes epithelial-mesenchymal transition and paclitaxel resistance through its interaction with integrin alpha(V)beta(3)in cancer cells
Gasca, J; Flores, ML; Jimenez-Guerrero, R; Saez, ME; Barragan, I; Ruiz-Borrego, M; Tortolero, M; Romero, F; Saez, C; Japon, MA – 2020
Review of concepts in therapeutic decision-making in HER2-negative luminal metastatic breast cancer
Alvarez-Lopez, I; Bezares, S; Portulas, ED; Garcia-Martinez, E; Garcia-Saenz, JA; Gil-Gil, M; de Duenas, EM; Ribelles, N; Bertran, AS – 2020
Energy System Assessment in Survivors of Breast Cancer…
Cuesta-Vargas, AI; Buchan, J; Pajares, B; Alba, E; Trinidad-Fernandez, M; Ruiz-Medina, S; Garcia-Almeida, JM; Rios-Lopez, MJ; Roldan-Jimenez, C – 2020
Safety of switching from intravenous to subcutaneous rituximab during first-line treatment of patients with non-Hodgkin lymphoma: the Spanish population of the MabRella study
Garcia-Munoz, R; Quero, C; Perez-Persona, E; Domingo-Garcia, A; Perez-Lopez, C; Villaescusa-de-la-Rosa, T; Martinez-Castro, AM; Arguinano-Perez, JM; Parra-Cuadrado, JF; Panizo, C – 2020
Epigenetic regulation of white adipose tissue in the onset of obesity and metabolic diseases
Castellano-Castillo, D; Ramos-Molina, B; Cardona, F; Queipo-Ortuno, MI – 2020
Situation, challenges, and SEOM recommendations for the future of undergraduate education in Oncology in Spain
Segui, MA; Cruz, JJ; Alba, E; Feliu, J; Jara, C; Rivera, F; Lescure, AR; Lorenzo, A; Martin, M – 2020
Expression-based, consistent biomarkers for prognosis and diagnosis in lung cancer
Arroyo, M; Larrosa, R; Gomez-Maldonado, J; Cobo, MA; Claros, MG; Bautista, R – 2020
Subclinical Arteriosclerosis is Associated with Common Vascular Risk Factors in Long-Term Survivors of Testicular Cancer,
Espildora-Hernandez, J; Diaz-Antonio, T; Baena-Espinar, J; Alonso-Calderon, I; Rioja, J; Alba-Conejo, E; Valdivielso, P; Sanchez-Chaparro, MA – 2020
Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response
Xiao, QY; Nobre, A; Pineiro, P; Berciano-Guerrero, MA; Alba, E; Cobo, M; Lauschke, VM; Barragan, I – 2020
The Role of the Gut Microbiome in Colorectal Cancer Development and Therapy Response
Sanchez-Alcoholado, L; Ramos-Molina, B; Otero, A; Laborda-Illanes, A; Ordonez, R; Medina, JA; Gomez-Millan, J; Queipo-Ortuno, MI – 2020
Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer
Sanchez-Alcoholado, L; Ordonez, R; Otero, A; Plaza-Andrade, I; Laborda-Illanes, A; Medina, JA; Ramos-Molina, B; Gomez-Millan, J; Queipo-Ortuno, MI – 2020
Treatment options beyond immunotherapy in patients with wild-type lung adenocarcinoma: a Delphi consensus
Isla, D; de Castro, J; Garcia-Campelo, R; Lianes, P; Felip, E; Garrido, P; Paz-Ares, L; Trigo, JM – 2020
Inertial Sensors Embedded in Smartphones as a Tool for Fatigue Assessment Based on Acceleration in Survivors of Breast Cancer.
Cuesta-Vargas, AI; Pajares, B; Trinidad-Fernandez, M; Alba, E; Roldan-Jimenez, C – 2020
VITAL phase 2 study: Upfront 5-fluorouracil, mitomycin-C, panitumumab and radiotherapy treatment in nonmetastatic squamous cell carcinomas of the anal canal (GEMCAD 09-02)
Feliu, J; Garcia-Carbonero, R; Capdevila, J; Guasch, I; Alonso-Orduna, V; Lopez, C; Garcia-Alfonso, P; Castanon, C; Sevilla, I; Cerezo, L; Conill, C; Quintana-Angel, B; Sanchez, ME; Ghanem, I; Martin-Richard, M; Lopez-Gomez, M; Leon, A; Caro, M; Fernandez, T; Maurel, J – 2020
A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma
van Brummelen, EMJ; Levchenko, E; Domine, M; Fennell, DA; Kindler, HL; Viteri, S; Gadgeel, S; Lopez, PG; Kostorov, V; Morgensztern, D; Orlov, S; Zauderer, MG; Vansteenkiste, JF; Baker-Neblett, K; Vasquez, J; Wang, XW; Bellovin, DI; Schellens, JHM; Yan, L; Mitrica, I; DeYoung, MP; Trigo, J – 2020
Lung cancer symptoms at diagnosis: results of a nationwide registry study
Ruano-Ravina, A; Provencio, M; de Juan, VC; Carcereny, E; Moran, T; Rodriguez-Abreu, D; Lopez-Castro, R; Albite, EC; Guirado, M; Gonzalez, LG; Massuti, B; Granados, ALO; Blasco, A; Cobo, M; Garcia-Campelo, R; Bosch, J; Trigo, J; Juan, O; de la Rosa, CA; Domine, M; Sala, M; Oramas, J; Casal-Rubio, J; Cerezo, S – 2020
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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