Clinical and Translational Research in Cancer 

Lines of Research

01.Clinical-translational research in breast, prostate, gynecological, digestive, and germ cell cancers

02.Translational research in the identification of epigenetic/genetic markers in early stages of cancer

03.Research on the use of new diagnostic techniques (liquid biopsy, etc.) and markers

04.Research on the relationship between the microbiota and cancer

05.Research on real-world data real world data

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NK cell-triggered CCL5/IFNγ-CXCL9/10 axis underlies the clinical efficacy of neoadjuvant anti-HER2 antibodies in breast cancer – JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Santana-Hernández, S; Suarez-Olmos, J; Servitja, S; Berenguer-Molins, P; Costa-Garcia, M; Comerma, L; Rea, A; Perera-Bel, J; Menendez, S; Arpí, O; Bermejo, B; Martínez, MT; Cejalvo, JM; Comino-Méndez, I; Pascual, J; Alba, E; López-Botet, M; Rojo, F; Rovira, A; Albanell, J; Muntasell, A – 2024 – 10.1186/s13046-023-02918-4

Olaparib monotherapy in advanced triple-negative breast cancer patients with homologous recombination deficiency and without germline mutations in BRCA1/2: The NOBROLA phase 2 study – BREAST

Cortés, A; López-Miranda, E; Fernández-Ortega, A; Carañana, V; Servitja, S; Urruticoechea, A; Lema-Roso, L; Márquez, A; Lazaris, A; Alcalá-López, D; Mina, L; Gener, P; Rodríguez-Morató, J; Antonarellij, G; Llombart-Cussac, A; Pérez-García, J; Cortés, J – 2024 – 10.1016/j.breast.2024.103834

Optimal [18F]FDG PET/CT Cutoff for Pathologic Complete Response in HER2-Positive Early Breast Cancer Patients Treated with Neoadjuvant Trastuzumab and Pertuzumab in the PHERGain Trial – JOURNAL OF NUCLEAR MEDICINE

Gebhart, G; Keyaerts, M; Guiot, T; Flamen, P; Ruiz-Borrego, M; Stradella, A; Bermejo, B; Escriva-de-Romani, S; Martínez, LC; Ribelles, N; Fernandez-Abad, M; Albacar, C; Colleoni, M; Garrigos, L; de Frutos, MA; Dalenc, F; Prat, A; Marmé, F; Schmid, P; Kerrou, K; Braga, S; Gener, P; Sampayo-Cordero, M; Cortés, J; Pérez-García, JM; Llombart-Cussac, A – 2024 – 10.2967/jnumed.123.266384

Prognostic impact of tumor location and gene expression profile in sporadic desmoid tumor – EUROPEAN JOURNAL OF CANCER

Carrillo-García, J; Hindi, N; Conceicao, M; Sala, MA; Ugalde, A; López-Pousa, A; Bagué, S; Sevilla, I; Vicioso, L; Ramos, R; Martínez-Trufero, J; Mateo, MCG; Cruz, J; Hernández-León, CN; Redondo, A; Mendiola, M; García, JM; Hernández, JE; Alvarez, R; Agra, C; de Juan-Ferré, A; Valverde, C; Cano, JM; de Sande, LM; Pérez-Fidalgo, JA; Lavernia, J; Marcilla, D; Gutiérrez, A; Moura, DS; Martín-Broto, J – 2024 – 10.1016/j.ejca.2024.114270

Gestational breast cancer: distinctive molecular and clinico-epidemiological features – JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

de la Haba-Rodríguez, JR; Mínguez, P; Rojo, F; Martín, M; Alba, E; Servitja, S; Prat, A; Pérez-Fidalgo, JA; Gavilá, J; Morales, C; Rodriguez-Lescure, A; Herrero, C; Peña-Enriquez, R; Herranz, J; Hernando, C; Hernández-Blanquisett, A; Guil-Luna, S; Martinez, MT; Blanch, S; Caballero, R; Martín, N; Pollán, M; Guerrero-Zotano, A; Bermejo, B – 2024 – 10.1007/s10911-024-09571-3

Prognostic Implications of Blood Immune-Cell Composition in Metastatic Castration-Resistant Prostate Cancer – CANCERS

Perez-Navarro, E; Conteduca, V; Funes, JM; Dominguez, JI; Martin-Serrano, M; Cremaschi, P; Fernandez-Perez, M; Gordoa, TA; Font, A; Vázquez-Estévez, S; González-del-Alba, A; Wetterskog, D; Mellado, B; Fernandez-Calvo, O; Méndez-Vidal, M; Climent, M; Duran, I; Gallardo, E; Sanchez, A; Santander, C; Sáez, M; Puente, J; Tudela, J; Marinas, C; López-Andreo, M; Castellano, D; Attard, G; Grande, E; Rosino, A; Botia, JA; Palma-Mendez, J; De Giorgi, U; Gonzalez-Billalabeitia, E – 2024 – 10.3390/cancers16142535

High Mechanical Conditioning by Tumor Extracellular Matrix Stiffness Is a Predictive Biomarker for Antifibrotic Therapy in HER2-Negative Breast Cancer – CLINICAL CANCER RESEARCH

Quintela-Fandino, M; Bermejo, B; Zamora, E; Moreno, F; García-Saenz, JA; Pernas, S; Martínez-Jañez, N; Jiménez, D; Adrover, E; de Andrés, R; Mourón, S; Bueno, MJ; Manso, L; Viñas, G; Alba, E; Llombart-Cussac, A; Cortés, J; Tebar, C; Roe, DJ; Grant, A; Watson, A; Colomer, R; Mouneimne, G – 2024 – 10.1158/1078-0432.CCR-24-1518

3-year invasive disease-free survival with chemotherapy de-escalation using an 18F-FDG-PET-based, pathological complete response-adapted strategy in HER2-positive early breast cancer (PHERGain): a randomised, open-label, phase 2 trial – LANCET

Pérez-García, JM; Cortés, J; Ruiz-Borrego, M; Colleoni, M; Stradella, A; Bermejo, B; Dalenc, F; Escrivá-de-Romaní, S; Martínez, LC; Ribelles, N; Marmé, F; Cortés, A; Albacar, C; Gebhart, G; Prat, A; Kerrou, K; Schmid, P; Braga, S; Di Cosimo, S; Gion, M; Antonarelli, G; Popa, C; Szostak, E; Alcalá-López, D; Gener, P; Rodríguez-Morató, J; Mina, L; Sampayo-Cordero, M; Llombart-Cussac, A – 2024 – 10.1016/S0140-6736(24)00054-0

Prospective Assessment of Bone Metabolism Biomarkers and Survival in Metastatic Castration-resistant Prostate Cancer Patients Treated with Radium-223: The PRORADIUM Study – EUROPEAN UROLOGY ONCOLOGY

Romero-Laorden, N; Lorente, D; de Velasco, G; Lozano, R; Herrera, B; Puente, J; López, PP; Medina, A; Almagro, E; Gonzalez-Billalabeitia, E; Villla-Guzman, JC; González-del-Alba, A; Borrega, P; Laínez, N; Fernández-Freire, A; Hernández, A; Rodriguez-Vida, A; Chirivella, I; Fernandez-Parra, E; López-Campos, F; Pacheco, MI; Morales-Barrera, R; Fernández, O; Villatoro, R; Luque, R; Hernando, S; Castellano, DC; Castro, E; Olmos, D – 2024 – 10.1016/j.euo.2023.09.015

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Members

    • Researcher in Charge
      Será Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

    Emilio Alba Conejo

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    ORCID
    SCOPUS

      • Investigador/a Sénior
        Será Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

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        • Investigador/a Asistencial Colaborador/a
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          • Investigador/a posdoctorales y/o junior
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            • Investigadores/as predoctorales y/o formación
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              • Technical staff
                Será Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

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