Clinical and Translational Research in Cancer 

Lines of Research

01.Clinical-translational research in breast, prostate, gynecological, digestive, and germ cell cancers

02.Translational research in the identification of epigenetic/genetic markers in early stages of cancer

03.Research on the use of new diagnostic techniques (liquid biopsy, etc.) and markers

04.Research on the relationship between the microbiota and cancer

05.Research on real-world data real world data

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Prognostic Implications of Blood Immune-Cell Composition in Metastatic Castration-Resistant Prostate Cancer – CANCERS

Perez-Navarro, E; Conteduca, V; Funes, JM; Dominguez, JI; Martin-Serrano, M; Cremaschi, P; Fernandez-Perez, M; Gordoa, TA; Font, A; Vázquez-Estévez, S; González-del-Alba, A; Wetterskog, D; Mellado, B; Fernandez-Calvo, O; Méndez-Vidal, M; Climent, M; Duran, I; Gallardo, E; Sanchez, A; Santander, C; Sáez, M; Puente, J; Tudela, J; Marinas, C; López-Andreo, M; Castellano, D; Attard, G; Grande, E; Rosino, A; Botia, JA; Palma-Mendez, J; De Giorgi, U; Gonzalez-Billalabeitia, E – 2024 – 10.3390/cancers16142535

High Mechanical Conditioning by Tumor Extracellular Matrix Stiffness Is a Predictive Biomarker for Antifibrotic Therapy in HER2-Negative Breast Cancer – CLINICAL CANCER RESEARCH

Quintela-Fandino, M; Bermejo, B; Zamora, E; Moreno, F; García-Saenz, JA; Pernas, S; Martínez-Jañez, N; Jiménez, D; Adrover, E; de Andrés, R; Mourón, S; Bueno, MJ; Manso, L; Viñas, G; Alba, E; Llombart-Cussac, A; Cortés, J; Tebar, C; Roe, DJ; Grant, A; Watson, A; Colomer, R; Mouneimne, G – 2024 – 10.1158/1078-0432.CCR-24-1518

3-year invasive disease-free survival with chemotherapy de-escalation using an 18F-FDG-PET-based, pathological complete response-adapted strategy in HER2-positive early breast cancer (PHERGain): a randomised, open-label, phase 2 trial – LANCET

Pérez-García, JM; Cortés, J; Ruiz-Borrego, M; Colleoni, M; Stradella, A; Bermejo, B; Dalenc, F; Escrivá-de-Romaní, S; Martínez, LC; Ribelles, N; Marmé, F; Cortés, A; Albacar, C; Gebhart, G; Prat, A; Kerrou, K; Schmid, P; Braga, S; Di Cosimo, S; Gion, M; Antonarelli, G; Popa, C; Szostak, E; Alcalá-López, D; Gener, P; Rodríguez-Morató, J; Mina, L; Sampayo-Cordero, M; Llombart-Cussac, A – 2024 – 10.1016/S0140-6736(24)00054-0

Prospective Assessment of Bone Metabolism Biomarkers and Survival in Metastatic Castration-resistant Prostate Cancer Patients Treated with Radium-223: The PRORADIUM Study – EUROPEAN UROLOGY ONCOLOGY

Romero-Laorden, N; Lorente, D; de Velasco, G; Lozano, R; Herrera, B; Puente, J; López, PP; Medina, A; Almagro, E; Gonzalez-Billalabeitia, E; Villla-Guzman, JC; González-del-Alba, A; Borrega, P; Laínez, N; Fernández-Freire, A; Hernández, A; Rodriguez-Vida, A; Chirivella, I; Fernandez-Parra, E; López-Campos, F; Pacheco, MI; Morales-Barrera, R; Fernández, O; Villatoro, R; Luque, R; Hernando, S; Castellano, DC; Castro, E; Olmos, D – 2024 – 10.1016/j.euo.2023.09.015

Increased blood draws for ultrasensitive ctDNA and CTCs detection in early breast cancer patients – NPJ BREAST CANCER

Alba-Bernal, A; Godoy-Ortiz, A; Domínguez-Recio, ME; López-López, E; Quirós-Ortega, ME; Sánchez-Martín, V; Roldán-Díaz, MD; Jiménez-Rodríguez, B; Peralta-Linero, J; Bellagarza-García, E; Troyano-Ramos, L; Garrido-Ruiz, G; Hierro-Martín, MI; Vicioso, L; González-Ortiz, A; Linares-Valencia, N; Velasco-Suelto, J; Carbajosa, G; Garrido-Aranda, A; Lavado-Valenzuela, R; Alvarez, M; Pascual, J; Comino-Méndez, I; Alba, E – 2024 – 10.1038/s41523-024-00642-6

Atezolizumab Combined With Platinum and Maintenance Niraparib for Recurrent Ovarian Cancer With a Platinum-Free Interval >6 Months: ENGOT-OV41/GEICO 69-O/ANITA Phase III Trial – JOURNAL OF CLINICAL ONCOLOGY

González-Martín, A; Rubio, MJ; Heitz, F; Christensen, RD; Colombo, N; Van Gorp, T; Romeo, M; Ray-Coquard, I; Gaba, L; Leary, A; De Sande, LM; Lebreton, C; Redondo, A; Fabbro, M; Ginesta, MPB; Follana, P; Pérez-Fidalgo, JA; Rodrigues, M; Santaballa, A; Sabatier, R; Bermejo-Pérez, MJ; Lotz, JP; Pardo, B; Marquina, G; Sánchez-Lorenzo, L; Quindós, M; Estévez-García, P; Alía, EG; Manso, L; Casado, V; Kommoss, S; Tognon, G; Henry, S; Bruchim, I; Oaknin, A; Selle, F – 2024 – 10.1200/JCO.24.00668

Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial – LANCET

Oaknin, A; Gladieff, L; Martínez-García, J; Villacampa, G; Takekuma, M; De Giorgi, U; Lindemann, K; Woelber, L; Colombo, N; Duska, L; Leary, A; Godoy-Ortiz, A; Nishio, S; Angelergues, A; Rubio, MJ; Fariñas-Madrid, L; Yamaguchi, S; Lorusso, D; Ray-Coquard, I; Manso, L; Joly, F; Alarcón, J; Follana, P; Romero, I; Lebreton, C; Pérez-Fidalgo, JA; Yunokawa, M; Dahlstrand, H; D’Hondt, V; Randall, L – 2024 – 10.1016/S0140-6736(23)02405-4

Lipidomic Analysis Reveals Alterations in Hepatic FA Profile Associated With MASLD Stage in Patients With Obesity – JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Núñez-Sánchez, MA; Martinez-Sánchez, MA; Martínez-Montoro, JI; Balaguer-Román, A; Murcia-García, E; Fernández-Ruiz, VE; Ferrer-Gómez, M; Martínez-Cáceres, CM; Sledzinski, T; Frutos, MD; Hernández-Morante, JJ; Fernández-Garcia, JC; Queipo-Ortuno, MI; Ruiz-Alcaraz, AJ; Mika, A; Ramos-Molina, B – 2024 – 10.1210/clinem/dgae028

Neoadjuvant letrozole and palbociclib in patients with HR-positive/HER2-negative early breast cancer and Oncotype DX Recurrence Score ≥18: DxCARTES study – ESMO OPEN

Guerrero-Zotano, A; Pérez-García, JM; Ruiz-Borrego, M; Bermejo, B; Gil-Gil, M; de la Haba, J; Conejo, EA; Quiroga, ; Carañana, ; Urruticoechea, A; Morales, S; Bellet, M; Antón, A; Fernández-Abad, M; Sánchez-Rovira, P; Calabuig, L; Pérez-Escuredo, J; Sampayo-Cordero, M; Cortés, J; Llombart-Cussac, A – 2024 – 10.1016/j.esmoop.2024.103733

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Members

    • Researcher in Charge
      Será Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

    Emilio Alba Conejo

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    ORCID
    SCOPUS

      • Investigador/a Sénior
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        • Investigador/a Asistencial Colaborador/a
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          • Investigador/a posdoctorales y/o junior
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            • Investigadores/as predoctorales y/o formación
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              • Technical staff
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