Clinical and Translational Research in Cancer 

Lines of Research

01.Clinical-translational research in breast, prostate, gynecological, digestive, and germ cell cancers

02.Translational research in the identification of epigenetic/genetic markers in early stages of cancer

03.Research on the use of new diagnostic techniques (liquid biopsy, etc.) and markers

04.Research on the relationship between the microbiota and cancer

05.Research on real-world data real world data

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Prospective Assessment of Bone Metabolism Biomarkers and Survival in Metastatic Castration-resistant Prostate Cancer Patients Treated with Radium-223: The PRORADIUM Study – EUROPEAN UROLOGY ONCOLOGY

Romero-Laorden, N; Lorente, D; de Velasco, G; Lozano, R; Herrera, B; Puente, J; López, PP; Medina, A; Almagro, E; Gonzalez-Billalabeitia, E; Villla-Guzman, JC; González-del-Alba, A; Borrega, P; Laínez, N; Fernández-Freire, A; Hernández, A; Rodriguez-Vida, A; Chirivella, I; Fernandez-Parra, E; López-Campos, F; Pacheco, MI; Morales-Barrera, R; Fernández, O; Villatoro, R; Luque, R; Hernando, S; Castellano, DC; Castro, E; Olmos, D – 2024 – 10.1016/j.euo.2023.09.015

Increased blood draws for ultrasensitive ctDNA and CTCs detection in early breast cancer patients – NPJ BREAST CANCER

Alba-Bernal, A; Godoy-Ortiz, A; Domínguez-Recio, ME; López-López, E; Quirós-Ortega, ME; Sánchez-Martín, V; Roldán-Díaz, MD; Jiménez-Rodríguez, B; Peralta-Linero, J; Bellagarza-García, E; Troyano-Ramos, L; Garrido-Ruiz, G; Hierro-Martín, MI; Vicioso, L; González-Ortiz, A; Linares-Valencia, N; Velasco-Suelto, J; Carbajosa, G; Garrido-Aranda, A; Lavado-Valenzuela, R; Alvarez, M; Pascual, J; Comino-Méndez, I; Alba, E – 2024 – 10.1038/s41523-024-00642-6

Atezolizumab Combined With Platinum and Maintenance Niraparib for Recurrent Ovarian Cancer With a Platinum-Free Interval >6 Months: ENGOT-OV41/GEICO 69-O/ANITA Phase III Trial – JOURNAL OF CLINICAL ONCOLOGY

González-Martín, A; Rubio, MJ; Heitz, F; Christensen, RD; Colombo, N; Van Gorp, T; Romeo, M; Ray-Coquard, I; Gaba, L; Leary, A; De Sande, LM; Lebreton, C; Redondo, A; Fabbro, M; Ginesta, MPB; Follana, P; Pérez-Fidalgo, JA; Rodrigues, M; Santaballa, A; Sabatier, R; Bermejo-Pérez, MJ; Lotz, JP; Pardo, B; Marquina, G; Sánchez-Lorenzo, L; Quindós, M; Estévez-García, P; Alía, EG; Manso, L; Casado, V; Kommoss, S; Tognon, G; Henry, S; Bruchim, I; Oaknin, A; Selle, F – 2024 – 10.1200/JCO.24.00668

Atezolizumab plus bevacizumab and chemotherapy for metastatic, persistent, or recurrent cervical cancer (BEATcc): a randomised, open-label, phase 3 trial – LANCET

Oaknin, A; Gladieff, L; Martínez-García, J; Villacampa, G; Takekuma, M; De Giorgi, U; Lindemann, K; Woelber, L; Colombo, N; Duska, L; Leary, A; Godoy-Ortiz, A; Nishio, S; Angelergues, A; Rubio, MJ; Fariñas-Madrid, L; Yamaguchi, S; Lorusso, D; Ray-Coquard, I; Manso, L; Joly, F; Alarcón, J; Follana, P; Romero, I; Lebreton, C; Pérez-Fidalgo, JA; Yunokawa, M; Dahlstrand, H; D’Hondt, V; Randall, L – 2024 – 10.1016/S0140-6736(23)02405-4

Lipidomic Analysis Reveals Alterations in Hepatic FA Profile Associated With MASLD Stage in Patients With Obesity – JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Núñez-Sánchez, MA; Martinez-Sánchez, MA; Martínez-Montoro, JI; Balaguer-Román, A; Murcia-García, E; Fernández-Ruiz, VE; Ferrer-Gómez, M; Martínez-Cáceres, CM; Sledzinski, T; Frutos, MD; Hernández-Morante, JJ; Fernández-Garcia, JC; Queipo-Ortuno, MI; Ruiz-Alcaraz, AJ; Mika, A; Ramos-Molina, B – 2024 – 10.1210/clinem/dgae028

Neoadjuvant letrozole and palbociclib in patients with HR-positive/HER2-negative early breast cancer and Oncotype DX Recurrence Score ≥18: DxCARTES study – ESMO OPEN

Guerrero-Zotano, A; Pérez-García, JM; Ruiz-Borrego, M; Bermejo, B; Gil-Gil, M; de la Haba, J; Conejo, EA; Quiroga, ; Carañana, ; Urruticoechea, A; Morales, S; Bellet, M; Antón, A; Fernández-Abad, M; Sánchez-Rovira, P; Calabuig, L; Pérez-Escuredo, J; Sampayo-Cordero, M; Cortés, J; Llombart-Cussac, A – 2024 – 10.1016/j.esmoop.2024.103733

Nivolumab plus platinum-doublet chemotherapy in treatment-naive patients with advanced grade 3 Neuroendocrine Neoplasms of gastroenteropancreatic or unknown origin: The multicenter phase 2 NICE-NEC trial (GETNE-T1913) – NATURE COMMUNICATIONS

Riesco-Martinez, MC; Capdevila, J; Alonso, V; Jimenez-Fonseca, P; Teule, A; Grande, E; Sevilla, I; Benavent, M; Alonso-Gordoa, T; Custodio, A; Anton-Pascual, B; Hernando, J; Polo, E; Castillo-Trujillo, OA; Lamas-Paz, A; Teijo, A; Rodriguez-Gil, Y; Soldevilla, B; Garcia-Carbonero, R – 2024 – 10.1038/s41467-024-50969-8

CD8+NKs as a potential biomarker of complete response and survival with lenalidomide plus R-GDP in the R2-GDP-GOTEL trial in recurrent/refractory diffuse large B cell lymphoma – FRONTIERS IN IMMUNOLOGY

Hontecillas-Prieto, L; García-Domínguez, DJ; Palazón-Carrión, N; García-Sancho, AM; Nogales-Fernández, E; Jiménez-Cortegana, C; Sánchez-León, ML; Silva-Romeiro, S; Flores-Campos, R; Carnicero-González, F; Ríos-Herranz, E; de la Cruz-vicente, F; Rodríguez-García, G; Fernández-Alvarez, R; Martínez-Banaclocha, N; Gumà-Padrò, J; Gómez-Codina, J; Salar-Silvestre, A; Rodríguez-Abreu, D; Gálvez-Carvajal, L; Labrador, J; Guirado-Risueño, M; Provencio-Pulla, M; Sánchez-Beato, M; Marylene, L; Alvaro-Naranjo, T; Casanova-Espinosa, M; Rueda-Domínguez, A; Sánchez-Margalet, V; de la Cruz-merino, L – 2024 – 10.3389/fimmu.2024.1293931

NK cell-triggered CCL5/IFNγ-CXCL9/10 axis underlies the clinical efficacy of neoadjuvant anti-HER2 antibodies in breast cancer – JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Santana-Hernández, S; Suarez-Olmos, J; Servitja, S; Berenguer-Molins, P; Costa-Garcia, M; Comerma, L; Rea, A; Perera-Bel, J; Menendez, S; Arpí, O; Bermejo, B; Martínez, MT; Cejalvo, JM; Comino-Méndez, I; Pascual, J; Alba, E; López-Botet, M; Rojo, F; Rovira, A; Albanell, J; Muntasell, A – 2024 – 10.1186/s13046-023-02918-4

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Members

    • Researcher in Charge
      Será Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

    Emilio Alba Conejo

    Email: 
    ORCID
    SCOPUS

      • Investigador/a Sénior
        Será Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

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        • Investigador/a Asistencial Colaborador/a
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          • Investigador/a posdoctorales y/o junior
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            • Investigadores/as predoctorales y/o formación
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              • Technical staff
                Será Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

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