Translational Research in Cancer Immunotherapy and Epigenetics
Lines of Research
01.Oncology and Hematology
02.Cancer Immunotherapy
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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Risk Prediction Tools Available for Germline BRCA1/2 Mutations Underperform in Prostate Cancer Patients
Oliva, L; Lozano, R; Llacer, C; Aragon, I; Pajares, BI; Saez, MI; Herrera-Imbroda, B; Montesa, A; Hernandez, D; Villatoro, R; Otero, A; Correa, R; Grau, G; Peinado, P; Pacheco, MI; Garcia-Galisteo, E; Rueda, A; Machuca, FJ; Alba, E; Marquez-Aragones, A; Olmos, D; Castro, E – 2021
Circulating myeloid-derived suppressor cells and regulatory T cells as immunological biomarkers in refractory/relapsed diffuse large B-cell lymphoma: translational results from the R2-GDP-GOTEL trial
Jimenez-Cortegana, C; Palazon-Carrion, N; Garcia-Sancho, AM; Nogales-Fernandez, E; Carnicero-Gonzalez, F; Rios-Herranz, E; de la Cruz-Vicente, F; Rodriguez-Garcia, G; Fernandez-Alvarez, R; Dominguez, AR; Casanova-Espinosa, M; Martinez-Banaclocha, N; Guma-Padro, J; Gomez-Codina, J; Labrador, J; Salar-Silvestre, A; Rodriguez-Abreu, D; Galvez-Carvajal, L; Provencio, M; Sanchez-Beato, M; Guirado-Risueno, M; Espejo-Garcia, P; Lejeune, M; Alvaro, T; Sanchez-Margalet, V; de la Cruz-Merino, L – 2021
Rovalpituzumab Tesirine as a Maintenance Therapy After First-Line Platinum-Based Chemotherapy in Patients With Extensive-Stage- SCLC: Results From the Phase 3 MERU Study
Johnson, ML; Zvirbule, Z; Laktionov, K; Helland, A; Cho, BC; Gutierrez, V; Colinet, B; Lena, H; Wolf, M; Gottfried, M; Okamoto, I; van der Leest, C; Rich, P; Hung, JY; Appenzeller, C; Sun, ZW; Maag, D; Luo, Y; Nickner, C; Vajikova, A; Komarnitsky, P; Bar, J – 2021
Contributions of nuclear medicine in paediatric non-tumour musculoskeletal pathology
Noriega-Alvarez, E; Diez, MDO; Gadea, LD; Viedma, SS; Loza, SM – 2021
SEOM clinical guideline for management of adult medulloblastoma (2020)
Luque, R; Benavides, M; del Barco, S; Egana, L; Garcia-Gomez, J; Martinez-Garcia, M; Perez-Segura, P; Pineda, E; Sepulveda, JM; Vieito, M – 2021
SEOM clinical guideline for the management of cutaneous melanoma (2020)
Majem, M; Manzano, JL; Marquez-Rodas, I; Mujika, K; Munoz-Couselo, E; Perez-Ruiz, E; de la Cruz-Merino, L; Espinosa, E; Gonzalez-Cao, M; Berrocal, A – 2021
Hypoxia as a driver of resistance to immunotherapy
Kopecka, J; Salaroglio, IC; Perez-Ruiz, E; Sarmento-Ribeiro, AB; Saponara, S; De Las Rivas, J; Riganti, C – 2021
Impact of intestinal dysbiosis-related drugs on the efficacy of immune checkpoint inhibitors in clinical practice.
Perez-Ruiz, E; Jimenez-Castro, J; Berciano-Guerrero, MA; Valdivia, J; Estalella-Mendoza, S; Toscano, F; Artacho, MRD; Garrido-Siles, M; Martinez-Bautista, MJ; Roldan, RV; Rivas-Ruiz, F; Nogales-Fernandez, E; Morales, C; Perez-Valderrama, B; De la Cruz-Merino, L; Rueda, A – 2020
Tipifarnib in recurrent, metastatic HRAS-mutant salivary gland cancer
Hanna, GJ; Guenette, JP; Chau, NG; Sayehli, CM; Wilhelm, C; Metcalf, R; Wong, DJ; Brose, M; Razaq, M; Perez-Ruiz, E; Cohen, EEW; Aggarwal, R; Scholz, C; Gualberto, A; Ho, AL – 2020
Nivolumab for Newly Diagnosed Advanced-Stage Classic Hodgkin Lymphoma: Safety and Efficacy in the Phase II CheckMate 205 Study
Ramchandren, R; Domingo-Domenech, E; Rueda, A; Trneny, M; Feldman, TA; Lee, HJ; Provencio, M; Sillaber, C; Cohen, JB; Savage, KJ; Willenbacher, W; Ligon, AH; Ouyang, J; Redd, R; Rodig, SJ; Shipp, MA; Sacchi, M; Sumbul, A; Armand, P; Ansell, SM – 2019
Prophylactic TNF blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy.
Perez-Ruiz, E; Minute, L; Otano, I; Alvarez, M; Ochoa, MC; Belsue, V; de Andrea, C; Rodriguez-Ruiz, ME; Perez-Gracia, JL; Marquez-Rodas, I; Llacer, C; Alvarez, M; de Luque, V; Molina, C; Teijeira, A; Berraondo, P; Melero, I – 2019
Nutritional risk and malnutrition rates at diagnosis of cancer in patients treated in outpatient settings: Early intervention protocol
Sanz, EA; Siles, MG; Fernandez, LR; Roldan, RV; Dominguez, AR; Abiles, J – 2019
Unraveling transformation of follicular lymphoma to diffuse large B-cell lymphoma.
Gonzalez-Rincon, J; Mendez, M; Gomez, S; Garcia, JF; Martin, P; Bellas, C; Pedrosa, L; Rodriguez-Pinilla, SM; Camacho, FI; Quero, C; Perez-Callejo, D; Rueda, A; Llanos, M; Gomez-Codina, J; Piris, MA; Montes-Moreno, S; Barcena, C; Rodriguez-Abreu, D; Menarguez, J; De la Cruz-Merino, L; Monsalvo, S; Parejo, C; Royuela, A; Kwee, I; Cascione, L; Arribas, A; Bertoni, F; Mollejo, M; Provencio, M; Sanchez-Beato, M – 2019
First hospital contact via the Emergency Department is an independent predictor of overall survival and disease-free survival in patients with colorectal cancer
Tellez, T; Garcia-Aranda, M; Zarcos-Pedrinaci, I; Rivas-Ruiz, F; Perez-Ruiz, E; Padilla-Ruiz, MDC; Bare, ML; Morales-Suarez-Varela, M; Rueda, A; Alcaide, J; Redondo, M – 2019
Four years of clinical experience with Radium-223 for the treatment of castration-resistant prostate cancer
Perez, RMA; Garcia, AD; Martinez, SG; Viedma, SS; Gerona, HP; Vinardel, MP; Garcia, JMJH – 2019
Role of Nuclear Medicine in the diagnosis of musculoskeletal infection: a review
Noriega-Alvarez, E; Gadea, LD; Diez, MPO; Valganon, VP; Viedma, SS; Jimenez, RG – 2019
Clinical and sociodemographic factors that may influence the resilience of women surviving breast cancer: cross-sectional study
Padilla-Ruiz, M; Ruiz-Roman, C; Perez-Ruiz, E; Rueda, A; Redondo, M; Rivas-Ruiz, F – 2019
Targeted Cancer Cell Killing by Highly Selective miRNA-Triggered Activation of a Prokaryotic Toxin-Antitoxin System
Turnbull, A; Bermejo-Rodriguez, C; Preston, MA; Garrido-Barros, M; Pimentel, B; de la Cueva-Mendez, G – 2019
Impact of adjuvant chemotherapy on the survival of patients with breast cancer diagnosed by screening
ZarcosPedrinaci, I; Redondo, M; Louro, J; Rivas-Ruiz, F; Tellez, T; Perez, D; Cano, FM; Machan, K; Domingo, L; Vernet, MM; Padilla-Ruiz, M; Castells, X; Rueda, A; Sala, M – 2019
Genetic Susceptibility in Head and Neck Squamous Cell Carcinoma in a Spanish Population
Fernandez-Mateos, J; Seijas-Tamayo, R; Klain, JCA; Borgonon, MP; Perez-Ruiz, E; Mesia, C; del Barco, E; Coloma, CS; Dominguez, AR; Daroqui, JC; Ruiz, EF; Ocana, A; Gonzalez-Sarmiento, R; Cruz-Hernandez, JJ – 2019
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

Antonio Rueda Domínguez
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Co-Investigadora ResponsableSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

María Isabel Barragán Mallofret
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Investigador/a SéniorSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigador/a Asistencial Colaborador/aSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigadores/as posdoctorales y/o juniorSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigadores/as predoctorales y/o en formaciónSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Technical staffSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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