Haematology and Haematotherapy
Lines of Research
01.Transplantation of hematopoietic precursors in adult and pediatric patients
02.CAR-T cell therapy (Chimeric Antigen Receptor-T): efficacy and quality of life studies
03.Study of rare diseases with a hematological basis: diagnosis and individualized treatment
04.Hemostasis and Thrombosis: Approach in the clinic and the laboratory of new therapies for patients with hemophilia. Digital tools for the management and analysis of information in hemophilia. Immune thrombocytopenia. Thrombophilia states of genetic and acquired origin. Thrombosis in Oncohematology
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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Multicéntrico, abierto, brazo único, fase II, Estudio exploratorio para evaluar el efecto de un año de consolidación de tratamiento con ponatinib 15 mg en la tasa de paciente con leucemia mieloide crónica filadelfia positivo en remisión libre de tratamiento que previamente habían alcanzado respuesta molecular profunda con imatinib
ANTONIO JIMÉNEZ VELASCO – ENSAYO CLINICO INDEPENDIENTE – II – FUNDACIÓN TEÓFILO HERNANDO
Long-term outcomes and renal responses following autologous hematopoietic stem cell transplantation for light chain deposition disease: a retrospective study on behalf of the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation – HAEMATOLOGICA
Garderet, L; Gras, L; Koster, L; de Wreede, L; Montserrat, R; Vincent, L; Fenk, R; Karunanithi, K; Deeren, D; Kaufmann, M; Kuball, J; Ozdogu, H; Cascon, MJP; Passweg, J; Rye, A; Salmenniemi, U; Snowden, J; Hansen, CT; Leleu, – 2024 – 10.3324/haematol.2023.284520
Haploidentical vs. HLA-matched donor hematopoietic stem-cell transplantation for pediatric patients with acute lymphoblastic leukemia in second remission: A collaborative retrospective study of the Spanish Group for Bone Marrow Transplantation in Children (GETMON/GETH) and the Spanish Childhood Relapsed ALL Board (ReALLNet) – FRONTIERS IN PEDIATRICS
Moreno, C; Ramos-Elbal, E; Velasco, P; Aguilar, Y; Martínez, BG; Fuentes, C; Molinos, A; Guerra-García, P; Palomo, P; Verdu, J; Pedroso, RMA; Vagace, JM; López-Duarte, M; Regueiro, A; Tasso, M; Dapena, JL; Salinas, JA; Navarro, S; Bautista, F; Lassaletta, A; Lendínez, F; Rives, S; Pascual, A; Rodríguez, A; Pérez-Hurtado, JM; Fernández, JM; Pérez-Martínez, A; González-Vicent, M; de Heredia, CD; Fuster, JL – 2023 – 10.3389/fped.2023.1140637
Impact of cytomegalovirus immunodominant HLA-I donor-recipient matching on the incidence and features of virus DNAemia and virus-specific T-cell immune reconstitution in unmanipulated haploidentical hematopoietic stem cell transplantation – TRANSPLANT INFECTIOUS DISEASE
Huntley, D; Giménez, E; Vázquez, L; Pascual, MJ; Amat, P; Remigia, MJ; Hernández-Boluda, JC; García, M; Gago, B; Torres, I; de la Asunción, CS; Hernani, R; Pérez, A; Albert, E; Piñana, JL; Solano, C; Navarro, D – 2023 – 10.1111/tid.14065
Impact of pre- and/or post-autologous stem cell transplantation exposure to brentuximab vedotin on survival outcomes in patients with high-risk Hodgkin lymphoma – ANNALS OF HEMATOLOGY
Martínez, C; de Haro, ME; Romero, S; Gutiérrez, A; Domingo-Domènech, E; González-Rodríguez, AP; Zeberio, I; Martínez-Badas, MP; Rodríguez-Izquierdo, A; Carpio, C; Bastos-Oreiro, M; Hernández-Rivas, JA; Vallansot, R; Kelleher, N; Díaz-Gálvez, FJ; Torrado, T; Pereira, A; García-Sanz, R – 2023 – 10.1007/s00277-022-05011-6
Impact of trisomy 19 on outcome according to genetic makeup in patients with acute myeloid leukemia – HAEMATOLOGICA
Kayser, S; Martínez-Cuadrón, D; Rodriguez-Veiga, R; Hänel, M; Tormo, M; Schäfer-Eckart, K; Botella, C; Stölzel, F; del Castillo, TB; Keller, U; Rodriguez-Medina, C; Held, G; Amigo, ML; Schliemann, C; Colorado, M; Kaufmann, M; Garcia, MB; Krause, SW; Görner, M; Jost, E; Steffen, B; Zukunft, S; Platzbecker, U; Ho, AD; Baldus, CD; Serve, H; Müller-Tidow, C; Thiede, C; Bornhäuser, M; Montesinos, P; Röllig, C; Schlenk, RF – 2023 – 10.3324/haematol.2022.282127
Kidney transplant in the next decade: Strategies, challenges and vision of the future – NEFROLOGIA
Hernández, D; Caballero, A – 2023 – 10.1016/j.nefroe.2022.04.008
Lenalidomide in combination with R-ESHAP in patients with relapsed or refractory diffuse large B-cell lymphoma: A phase 2 study from GELTAMO – BRITISH JOURNAL OF HAEMATOLOGY
García-Sancho, AM; Baile, M; Rodríguez, G; Dlouhy, I; Sancho, JM; Jarque, I; González-Barca, E; Salar, A; Espeso, M; Grande, C; Bergua, J; Montes-Moreno, S; Redondo, A; Enjuanes, A; Campo, E; López-Guillermo, A; Caballero, D – 2023 – 10.1111/bjh.18989
Low rate of infectious enterocolitis in allogeneic stem cell transplant recipients with acute diarrhea: A prospective study by the GETH-TC. – ACTA HAEMATOLOGICA
Velao, SR; Cadenas, IG; Cuesta, MA; Sanchez-Ortega, I; Fernández-Avilés, F; Roldan, E; Torrent, A; Viguria, MC; Villar, S; Bento, L; Yañez, L; Martino, R; Piñana, JL – 2023 – 10.1159/000528242
One-year breakthrough SARS-CoV-2 infection and correlates of protection in fully vaccinated hematological patients – BLOOD CANCER JOURNAL
Piñana, JL; Vazquez, L; Calabuig, M; López-Corral, L; Martin-Martin, G; Villalon, L; Sanz-Linares, G; Conesa-Garcia, V; Sanchez-Salinas, A; Gago, B; Facal, A; Risco-Gálvez, I; Olave, MT; Espigado, I; Lopez-Jimenez, J; Hernández-Rivas, JA; Avendaño-Pita, A; Arroyo, I; Ferrer, E; García-Cadenas, I; González-Santillana, C; Roldán-Pérez, A; Ferrer, B; Guerreiro, M; Suarez-Lledó, M; Camara, A; Campos-Beltrán, D; Navarro, D; Cedillo, A; Sureda, A; Solano, C; Martino, R – 2023 – 10.1038/s41408-022-00778-3
Results of haploidentical transplant in patients with donor-specific antibodies: a survey on behalf of the Spanish Group of Hematopoietic Transplant and Cell Therapy – FRONTIERS IN IMMUNOLOGY
Bailén, R; Alenda, R; Herruzo-Delgado, B; Acosta-Fleitas, C; Vallés, A; Esquirol, A; Fonseca, M; Solán, L; Sánchez-Vadillo, I; Bautista, G; Bento, L; López-Godino, O; Pérez-Martínez, A; Torrent, A; Zanabili, J; Calbacho, M; Moreno, MA; Pascual-Cascón, MJ; Guerra-Domínguez, L; Chinea, A; García-Cadenas, I; López-Corral, L; Boix-Giner, F; Lórenzo, JLL; Humala, K; Duarte, R; Sampol, A; Heras, I; Vicario, JL; Balas, A; Oarbeascoa, G; Fernández-Caldas, P; Anguita, J; Kwon, M – 2023 – 10.3389/fimmu.2023.1165759
Role of allogeneic hematopoietic cell transplant for relapsed/refractory aggressive B-cell lymphomas in the CART era – BONE MARROW TRANSPLANTATION
Mussetti, A; Bento, L; Bastos-Oreiro, M; Sansalvador, BR; Albo, C; Bailen, R; Barba, P; Benzaquén, A; Briones, J; Caballero, AC; Campos, A; Español, I; Ferra, C; López, SG; Sierra, PAG; Guerra, LM; Hernani, R; Iacoboni, G; Ubieto, AIJ; Kwon, M; Corral, LL; López-Godino, O; Munoz, MCM; Martínez-Cibrián, N; Gómez, JM; Pérez-Ortega, L; Ortf, G; Ortiz-Maldonado, V; Pascual, MJ; Perera, M; Perez, A; Reguera, JL; Sanchez, JM; Sanz, J; Torrent, A; Yáñez, L; Varela, R; Echechipia, IC; Caballero, D; Sureda, A – 2023 – 10.1038/s41409-023-01949-x
SARS-CoV-2-reactive antibody waning, booster effect and breakthrough SARS-CoV-2 infection in hematopoietic stem cell transplant and cell therapy recipients at one year after vaccination – BONE MARROW TRANSPLANTATION
Pinana, JL; Martino, R; Vazquez, L; Lopez-Corral, L; Perez, A; Chorao, P; Avendano-Pita, A; Pascual, MJ; Sanchez-Salinas, A; Sanz-Linares, G; Olave, MT; Arroyo, I; Tormo, M; Villalon, L; Conesa-Garcia, V; Gago, B; Terol, MJ; Villalba, M; Garcia-Gutierrez, V; Cabero, A; Hernandez-Rivas, JA; Ferrer, E; Garcia-Cadenas, I; Teruel, A; Navarro, D; Cedillo, A; Sureda, A; Solano, C – 2023 – 10.1038/s41409-023-01946-0
Survival Outcomes and Health-Related Quality of Life in Older Adults Diagnosed with Acute Myeloid Leukemia Receiving Frontline Therapy in Daily Practice – JOURNAL OF PERSONALIZED MEDICINE
Ramos, F; Hermosín, ML; Fuertes-Núñez, M; Martínez, P; Rodriguez-Medina, C; Barrios, M; Ibáñez, F; Bernal, T; Olave, MT; Alvarez, MA; Vahí, M; Caballero-Velázquez, T; González, B; Altés, A; García, L; Fernández, P; Durán, MA; López, R; Rafel, M; Serrano, J; Ranelletti, FO – 2023 – 10.3390/jpm13121667
Time-Dependent Changes of Klotho and FGF-23 Levels after Kidney Transplantation: Role of Cold Ischemia Time, Renal Function and Graft Inflammation. – JOURNAL OF CLINICAL MEDICINE
Vazquez-Sanchez, T; Sanchez-Niño, MD; Ruiz-Esteban, P; López, V; León, M; Caballero, A; Ruiz-Escalera, JF; Ortiz, A; Torres, A; Rodriguez, M; Hernandez, D – 2023 – 10.3390/jcm12134486
A Phase I/II Open-Label Study of Molibresib for the Treatment of Relapsed/Refractory Hematologic Malignancies – CLINICAL CANCER RESEARCH
Dawson, Mark A.; Borthakur, Gautam; Huntly, Brian J. P.; Karadimitris, Anastasios; Alegre, Adrian; Chaidos, Aristeidis; Vogl, Dan T.; Pollyea, Daniel A.; Davies, Faith E.; Morgan, Gareth J.; Glass, Jacob L.; Kamdar, Manali; Mateos, Maria -Victoria; Tovar, Natalia; Yeh, Paul; Delgado, Regina Garcia; Basheer, Faisal; Marando, Ludovica; Gallipoli, Paolo; Wyce, Anastasia; Krishnatry, Anu Shilpa; Barbash, Olena; Bakirtzi, Evi; Ferron-Brady, Geraldine; Karpinich, Natalie O.; McCabe, Michael T.; Foley, Shawn W.; Horner, Thierry; Dhar, Arindam; Kremer, Brandon E.; Dickinson, Michael – 2023 – 10.1158/1078-0432.CCR-22-1284
Toxicity of Asciminib in Real Clinical Practice: Analysis of Side Effects and Cross-Toxicity with Tyrosine Kinase Inhibitors – CANCERS
Perez-Lamas, L; Luna, A; Boque, C; Xicoy, B; Giraldo, P; Lopez, RP; Nuno, CR; de las Heras, N; Castera, EM; Marin, JL; Diaz, AS; Gomez, V; Tenza, PV; Pacho, MS; Goni, JAV; Vega, MM; Alvarez-Larran, A; Cortes, M; Encinas, MP; Mastell, PC; Angona, A; Rosell, A; Lakhwani, S; Colorado, M; Ramila, E; Cervero, C; Cuevas, B; Blanco, LV; de Paz, R; Coll, AP; Fernandez, MJ; Casado, LF; Alonso-Dominguez, JM; Arance, MMA; Cuenca, AS; Jimenez-Velasco, A; Prendes, SO; Santaliestra, M; Chulvi, MJL; Hernandez-Boluda, JC; Garcia-Gutierrez, V – 2023 – 10.3390/cancers15041045
Excellent hemostatic control during cardiac surgery in a patient with hemophilia B treated with albutrepenonacog alfa (rIX-FP): A case report – CLINICAL CASE REPORTS
Lopez-Jaime, FJ; Fernandez-Bello, I; Calavia-Aranda, E; Reina-Monso, B; Montano, A – 2023 – 10.1002/ccr3.7439
Treatment-free remission after dasatinib in patients with chronic myeloid leukaemia in chronic phase with deep molecular response: Final 5-year analysis of DASFREE – BRITISH JOURNAL OF HAEMATOLOGY
Shah, NP; Garcia-Gutierrez, V; Jimenez-Velasco, A; Larson, SM; Saussele, S; Rea, D; Mahon, FX; Levy, MY; Gomez-Casares, MT; Mauro, MJ; Sy, O; Martin-Regueira, P; Lipton, JH – 2023 – 10.1111/bjh.18883
Expert opinion paper on the treatment of hemophilia a with emicizumab – HEMATOLOGY
Lopez-Jaime, FJ; Benitez, O; Jordan, BLD; Montano, A; Coll, J; Paris, LQ; Solano, MDGD – 2023 – 10.1080/16078454.2023.2166334
Treosulfan-Based Conditioning Regimen In Pediatric Hematopoietic Stem Cell Transplantation: A Retrospective Analysis on Behalf of the Spanish Group for Hematopoietic Transplantation and Cellular Therapy (GETH-TC) – TRANSPLANTATION AND CELLULAR THERAPY
Galán, V; Beléndez, C; Echecopar, C; Estival, P; Sissini, L; Olivas, R; Bueno, D; Molina, B; Fuentes, C; Regueiro, A; Benítez, I; Plaza, M; Margarit, A; Rifón, J; Pascual, A; Palomo, P; Urtasun, A; Fuster, JL; Fuster, L; de Heredia, CD; Navarro, JMF; González-Vicent, M; Ruz, B; Pérez-Martínez, A – 2023 – 10.1016/j.jtct.2023.08.016
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

Francisco José López Jaime
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Investigador/a SéniorSerán aquellos que tengan una actividad investigadora de al menos 5 años en la etapa posdoctoral. Estos investigadores estarán adscritos a un Grupo de Investigación liderado por un Investigador Responsable. Las funciones serán las que le tenga asignadas su IR.
Pueden liderar una línea de investigación de alguno de los grupos de investigación del Instituto, con financiación competitiva propia, y con potencial para llegar a convertirse responsable de un grupo de investigación.
MANUEL BARRIOS GARCÍA
Perfil investigador: R3. A.1.
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Investigador/a Asistencial Colaborador/aSerá Investigador Asistencial Colaborador el Investigador que no reúne la consideración de Investigador Posdoctoral. Estarán adscritos a un Grupo de Investigación liderado por un IR. Las funciones serán las que le tenga asignada su IR.
SILVESTRE MARTÍNEZ GARCÍA
Perfil investigador/a: R3. A.2.
CONCEPCIÓN RUIZ NUÑO
Perfil investigador: R3. A.2.
ALBERTO TORÍO RUIZ
Perfil investigador: R3. A.2.
ANTONIA PASCUAL MARTÍNEZ
Perfil investigador: R3. A.2.
ANA ISABEL RODRÍGUEZ JIMÉNEZ
Perfil investigador: R3. A.2.
MANUEL ISIDRO MUÑOZ PÉREZ
Perfil investigador: R3. A.2.
MACARENA ORTÍZ PAREJA
Perfil investigador: R3. A.2.
MARÍA JESÚS PASCUAL CASCÓN
Perfil investigador: R3. A.2.
ABELARDO CABALLERO GONZÁLEZ
Perfil investigador: R3. A.2.
ALEJANDRO CONTENTO GONZALO
Perfil investigador: R3. A.2.
MARÍA ÁNGELES CUESTA CASAS
Perfil investigador: R3. A.2.
MANUEL ESPESO DE HARO
Perfil investigador: R3. A.2.
MAGDALENA ALCALÁ PEÑA
Perfil investigador: R3. A.2.
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Investigadores/as posdoctorales y/o juniorEsta etapa posdoctoral estará restringida a Investigadores del Instituto que tengan el título doctor y no contemplados en los perfiles posteriores. Durante su etapa posdoctoral pueden llegar a liderar proyectos de I+D+i como Investigadores Principales, aunque aún no hayan establecido un nivel significativo de independencia. Además, pueden tener actividades de docencia y/o asistencial más allá de su trabajo de investigación.
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Technical staff
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)