Hepatogastroenterology, Pharmacology, and Translational Clinical Therapeutics
Lines of Research
02.Etiopathogenesis and new treatments in inflammatory bowel disease
03.Etiopathogenesis, clinical course, and non-invasive diagnosis of non-alcoholic fatty liver disease
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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Microbiota diversity in nonalcoholic fatty liver disease and in drug-induced liver injury
Rodriguez-Diaz, C; Taminiau, B; Garcia-Garcia, A; Cueto, A; Robles-Diaz, M; Ortega-Alonso, A; Martin-Reyes, F; Daube, G; Sanabria-Cabrera, J; Jimenez-Perez, M; Lucena, MI; Andrade, RJ; Garcia-Fuentes, E; Garcia-Cortes, M – 2022
Setting up criteria for drug-induced autoimmune-like hepatitis through a systematic analysis of published reports
Bjornsson, ES; Medina-Caliz, I; Andrade, RJ; Lucena, MI – 2022
Modeling drug-induced liver injury: current status and future prospects
Di Zeo-Sanchez, DE; Segovia-Zafra, A; Matilla-Cabello, G; Pinazo-Bandera, JM; Andrade, RJ; Lucena, MI; Villanueva-Paz, M – 2022
Significant heterogeneity in the diagnosis and long-term management of Wilson disease: Results from a large multicenter Spanish study.
Berenguer, Marina; Vergara, Mercedes; Almohalla, Carolina; Hernandez, Alicia; Blanco, Sonia; Testillano, Milagros; Girona, Eva; Casado, Marta; Garcia, Miren; Catalina, Maria-Vega; Munoz, Carolina; Gutierrez, Maria Luisa; Molina, Esther; Romero, Miriam; Otero, Alejandra; Hernaez-Alsina, Tania; Bernal-Monterde, Vanessa; Lorente, Sara; Masnou, Helena; Bonet, Lucia; Soto, Susana; Gisbert, Concha; Valer, Maria-Paz; Gomez, Judith; Pacheco, Gemma; Morillas, Julia; Gonzalez, Martha; Dominguez, Nuria; Lazaro, Maria; Pascual, Sonia; Castello, Immaculada; Gonzalez, Rocio – 2022
Differential iNKT and T Cells Activation in Non-Alcoholic Fatty Liver Disease and Drug-Induced Liver Injury
Caballano-Infantes, E; Garcia-Garcia, A; Lopez-Gomez, C; Cueto, A; Robles-Diaz, M; Ortega-Alonso, A; Martin-Reyes, F; Alvarez-Alvarez, I; Arranz-Salas, I; Ruiz-Cabello, F; Lucena, IM; Garcia-Fuentes, E; Andrade, RJ; Garcia-Cortes, M – 2022
Modeling Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes Syndrome Using Patient-Derived Induced Neurons Generated by Direct Reprogramming
Povea-Cabello, S; Villanueva-Paz, M; Villalon-Garcia, I; Talaveron-Rey, M; Alvarez-Cordoba, M; Suarez-Rivero, JM; Montes, MA; Rodriguez-Moreno, A; Andrade-Talavera, Y; Armengol, JA; Sanchez-Alcazar, JA – 2022
The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality
Hershey, MS; Martinez-Gonzalez, MA; Alvarez-Alvarez, I; Hernandez, JAM; Ruiz-Canela, M – 2022
Endoscopic Intragastric Injection of Botulinum Toxin A in Obese Patients Accelerates Weight Loss after Bariatric Surgery: Follow-Up of a Randomised Controlled Trial (IntraTox Study);
Sanchez-Torralvo, FJ; Vazquez-Pedreno, L; Gonzalo-Marin, M; Tapia, MJ; Lima, F; Garcia-Fuentes, E; Garcia, P; Moreno-Ruiz, J; Rodriguez-Canete, A; Valdes, S; Olveira, G – 2022
Morbid Obesity in Women Is Associated with an Altered Intestinal Expression of Genes Related to Cancer Risk and Immune, Defensive, and Antimicrobial Response;
Ho-Plagaro, A; Rodriguez-Diaz, C; Santiago-Fernandez, C; Lopez-Gomez, C; Garcia-Serrano, S; Martin-Reyes, F; Rodriguez-Pacheco, F; Rodriguez-Canete, A; Alcain-Martinez, G; Vazquez-Pedreno, L; Valdes, S; Garrido-Sanchez, L; Garcia-Fuentes, E – 2022
Therapeutic Management of Idiosyncratic Drug-Induced Liver Injury and Acetaminophen Hepatotoxicity in the Paediatric Population: A Systematic Review
Niu, H; Atallah, E; Alvarez-Alvarez, I; Medina-Caliz, I; Aithal, GP; Arikan, C; Andrade, RJ; Lucena, MI – 2022
Characterizing Highly Cited Papers in Mass Cytometry through H-Classics.
Di Zeo-Sanchez, DE; Sanchez-Nunez, P; Stephens, C; Lucena, MI – 2021
Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials
Hey-Hadavi, J; Seekins, D; Palmer, M; Coffey, D; Caminis, J; Abdullaev, S; Patwardhan, M; Tyler, H; Raheja, R; Stanley, AM; Pineda-Salgado, L; Bourdet, DL; Andrade, RJ; Hayashi, PH; Dimick-Santos, L; Rockey, DC; Estilo, A – 2021
Clinical Characteristics and Outcome of Drug-Induced Liver Injury in the Older Patients: From the Young-Old to the Oldest-Old.
Weersink, RA; Alvarez-Alvarez, I; Medina-Caliz, I; Sanabria-Cabrera, J; Robles-Diaz, M; Ortega-Alonso, A; Garcia-Cortes, M; Bonilla, E; Niu, H; Soriano, G; Jimenez-Perez, M; Hallal, H; Blanco, S; Kaplowitz, N; Lucena, MI; Andrade, RJ – 2021
Oxidative Stress in Drug-Induced Liver Injury (DILI): From Mechanisms to Biomarkers for Use in Clinical Practice
Villanueva-Paz, M; Moran, L; Lopez-Alcantara, N; Freixo, C; Andrade, RJ; Lucena, MI; Cubero, FJ – 2021
Combination of Tocilizumab and Steroids to Improve Mortality in Patients with Severe COVID-19 Infection: A Spanish, Multicenter, Cohort Study.
Ruiz-Antoran, Belen; Sancho-Lopez, Aranzazu; Torres, Ferran; Moreno-Torres, Victor; de Pablo-Lopez, Itziar; Garcia-Lopez, Paulina; Abad-Santos, Francisco; Rosso-Fernandez, Clara M; Aldea-Perona, Ana; Montane, Eva; Aparicio-Hernandez, Ruth M; Llop-Rius, Roser; Pedros, Consuelo; Gijon, Paloma; Hernandez-Carballo, Carolina; Pedrosa-Martinez, Maria J; Rodriguez-Jimenez, Consuelo; Prada-Ramallal, Guillermo; Cabrera-Garcia, Lourdes; Aguilar-Garcia, Josefa A; Sanjuan-Jimenez, Rocio; Ortiz-Barraza, Evelyn I; Sanchez-Chica, Enrique; Fernandez-Cruz, Ana – 2021
Oxidized LDL Increase the Proinflammatory Profile of Human Visceral Adipocytes Produced by Hypoxia
Santiago-Fernandez, C; Martin-Reyes, F; Tome, M; Gutierrez-Repiso, C; Fernandez-Garcia, D; Ocana-Wilhelmi, L; Rivas-Becerra, J; Tatzber, F; Pursch, E; Tinahones, FJ; Garcia-Fuentes, E; Garrido-Sanchez, L – 2021
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry.
Stephens, C; Robles-Diaz, M; Medina-Caliz, I; Garcia-Cortes, M; Ortega-Alonso, A; Sanabria-Cabrera, J; Gonzalez-Jimenez, A; Alvarez-Alvarez, I; Slim, M; Jimenez-Perez, M; Gonzalez-Grande, R; Fernandez, MC; Casado, M; Soriano, G; Roman, E; Hallal, H; Romero-Gomez, M; Castiella, A; Conde, I; Prieto, M; Moreno-Planas, JM; Giraldez, A; Moreno-Sanfiel, JM; Kaplowitz, N; Lucena, MI; Andrade, RJ – 2021
Immune-Mediated Drug-Induced Liver Injury: Immunogenetics and Experimental Models
Gerussi, A; Natalini, A; Antonangeli, F; Mancuso, C; Agostinetto, E; Barisani, D; Di Rosa, F; Andrade, R; Invernizzi, P – 2021
Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction
Segovia-Zafra, A; Zeo-Sanchez, DED; Lopez-Gomez, C; Perez-Valdes, Z; Garcia-Fuentes, E; Andrade, RJ; Lucena, MI; Villanueva-Paz, M – 2021
Consensus Guidelines: Best Practices for Detection, Assessment and Management of Suspected Acute Drug-Induced Liver Injury During Clinical Trials in Adults with Chronic Viral Hepatitis and Adults with Cirrhosis Secondary to Hepatitis B, C and Nonalcoholic Steatohepatitis
Treem, WR; Palmer, M; Lonjon-Domanec, I; Seekins, D; Dimick-Santos, L; Avigan, MI; Marcinak, JF; Dash, A; Regev, A; Maller, E; Patwardhan, M; Lewis, JH; Rockey, DC; Di Bisceglie, AM; Freston, JW; Andrade, RJ; Chalasani, N – 2021
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
Raúl J. Andrade Bellido
Email: andrade@uma.es
ORCID
SCOPUS
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Co-investigator in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
Eduardo García Fuentes
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Co-Investigadora ResponsableSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
Mercedes Robles Díaz
Email: mrobles@uma.es
ORCID
SCOPUS
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Investigador/a SéniorSerán aquellos que tengan una actividad investigadora de al menos 5 años en la etapa posdoctoral. Estos investigadores estarán adscritos a un Grupo de Investigación liderado por un Investigador Responsable. Las funciones serán las que le tenga asignadas su IR.
Pueden liderar una línea de investigación de alguno de los grupos de investigación del Instituto, con financiación competitiva propia, y con potencial para llegar a convertirse responsable de un grupo de investigación.
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Investigador/a Asistencial Colaborador/aSerá Investigador Asistencial Colaborador el Investigador que no reúne la consideración de Investigador Posdoctoral. Estarán adscritos a un Grupo de Investigación liderado por un IR. Las funciones serán las que le tenga asignada su IR.
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Investigadores/as posdoctorales y/o juniorEsta etapa posdoctoral estará restringida a Investigadores del Instituto que tengan el título doctor y no contemplados en los perfiles posteriores. Durante su etapa posdoctoral pueden llegar a liderar proyectos de I+D+i como Investigadores Principales, aunque aún no hayan establecido un nivel significativo de independencia. Además, pueden tener actividades de docencia y/o asistencial más allá de su trabajo de investigación.
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Investigadores/as predoctorales y/o en formación
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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Technical staff
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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