Hepatogastroenterology, Pharmacology, and Translational Clinical Therapeutics
Lines of Research
02.Etiopathogenesis and new treatments in inflammatory bowel disease
03.Etiopathogenesis, clinical course, and non-invasive diagnosis of non-alcoholic fatty liver disease
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen
Rodriguez-Agudo, R; Goikoetxea-Usandizaga, N; Serrano-Macia, M; Fernandez-Tussy, P; Fernandez-Ramos, D; Lachiondo-Ortega, S; Gonzalez-Recio, I; Gil-Pitarch, C; Mercado-Gomez, M; Moran, L; Bizkarguenaga, M; Lopitz-Otsoa, F; Petrov, P; Bravo, M; Van Liempd, SM; Falcon-Perez, JM; Zabala-Letona, A; Carracedo, A; Castell, JV; Jover, R; Martinez-Cruz, LA; Delgado, TC; Cubero, FJ; Lucena, MI; Andrade, RJ; Mabe, J; Simon, J; Martinez-Chantar, ML – 2022
Safety of treating acute liver injury and failure
Garcia-Cortes, M; Ortega-Alonso, A; Andradeon, RJ – 2022
Beneficial effect of ursodeoxycholic acid in patients with acyl-CoA oxidase 2 (ACOX2) deficiency-associated hypertransaminasemia
Alonso-Pena, M; Espinosa-Escudero, R; Herraez, E; Briz, O; Cagigal, ML; Gonzalez-Santiago, JM; Ortega-Alonso, A; Fernandez-Rodriguez, C; Bujanda, L; Sanchez, MC; D’Avola, D; Londono, MC; Diago, M; Fernandez-Checa, JC; Garcia-Ruiz, C; Andrade, RJ; Lammert, F; Prieto, J; Crespo, J; Juamperez, J; Diaz-Gonzalez, A; Monte, MJ; Marin, JJG – 2022
Microbiota diversity in nonalcoholic fatty liver disease and in drug-induced liver injury
Rodriguez-Diaz, C; Taminiau, B; Garcia-Garcia, A; Cueto, A; Robles-Diaz, M; Ortega-Alonso, A; Martin-Reyes, F; Daube, G; Sanabria-Cabrera, J; Jimenez-Perez, M; Lucena, MI; Andrade, RJ; Garcia-Fuentes, E; Garcia-Cortes, M – 2022
Setting up criteria for drug-induced autoimmune-like hepatitis through a systematic analysis of published reports
Bjornsson, ES; Medina-Caliz, I; Andrade, RJ; Lucena, MI – 2022
Modeling drug-induced liver injury: current status and future prospects
Di Zeo-Sanchez, DE; Segovia-Zafra, A; Matilla-Cabello, G; Pinazo-Bandera, JM; Andrade, RJ; Lucena, MI; Villanueva-Paz, M – 2022
Significant heterogeneity in the diagnosis and long-term management of Wilson disease: Results from a large multicenter Spanish study.
Berenguer, Marina; Vergara, Mercedes; Almohalla, Carolina; Hernandez, Alicia; Blanco, Sonia; Testillano, Milagros; Girona, Eva; Casado, Marta; Garcia, Miren; Catalina, Maria-Vega; Munoz, Carolina; Gutierrez, Maria Luisa; Molina, Esther; Romero, Miriam; Otero, Alejandra; Hernaez-Alsina, Tania; Bernal-Monterde, Vanessa; Lorente, Sara; Masnou, Helena; Bonet, Lucia; Soto, Susana; Gisbert, Concha; Valer, Maria-Paz; Gomez, Judith; Pacheco, Gemma; Morillas, Julia; Gonzalez, Martha; Dominguez, Nuria; Lazaro, Maria; Pascual, Sonia; Castello, Immaculada; Gonzalez, Rocio – 2022
Differential iNKT and T Cells Activation in Non-Alcoholic Fatty Liver Disease and Drug-Induced Liver Injury
Caballano-Infantes, E; Garcia-Garcia, A; Lopez-Gomez, C; Cueto, A; Robles-Diaz, M; Ortega-Alonso, A; Martin-Reyes, F; Alvarez-Alvarez, I; Arranz-Salas, I; Ruiz-Cabello, F; Lucena, IM; Garcia-Fuentes, E; Andrade, RJ; Garcia-Cortes, M – 2022
Modeling Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes Syndrome Using Patient-Derived Induced Neurons Generated by Direct Reprogramming
Povea-Cabello, S; Villanueva-Paz, M; Villalon-Garcia, I; Talaveron-Rey, M; Alvarez-Cordoba, M; Suarez-Rivero, JM; Montes, MA; Rodriguez-Moreno, A; Andrade-Talavera, Y; Armengol, JA; Sanchez-Alcazar, JA – 2022
The Mediterranean diet and physical activity: better together than apart for the prevention of premature mortality
Hershey, MS; Martinez-Gonzalez, MA; Alvarez-Alvarez, I; Hernandez, JAM; Ruiz-Canela, M – 2022
Biomarkers of idiosyncratic drug-induced liver injury (DILI)-a systematic review
Atallah, E; Freixo, C; Alvarez-Alvarez, I; Cubero, FJ; Gerbes, AL; Kullak-Ublick, GA; Aithal, GP – 2021
Gut Microbiota Metabolism of Bile Acids Could Contribute to the Bariatric Surgery Improvements in Extreme Obesity,
Ocana-Wilhelmi, L; Martin-Nunez, GM; Ruiz-Limon, P; Alcaide, J; Garcia-Fuentes, E; Gutierrez-Repiso, C; Tinahones, FJ; Moreno-Indias, I – 2021
Oleic acid restores the rhythmicity of the disrupted circadian rhythm found in gastrointestinal explants from patients with morbid obesity
Lago-Sampedro, A; Ho-Plagaro, A; Garcia-Serrano, S; Santiago-Fernandez, C; Rodriguez-Diaz, C; Lopez-Gomez, C; Martin-Reyes, F; Ruiz-Aldea, G; Alcain-Martinez, G; Gonzalo, M; Montiel-Casado, C; Fernandez, JR; Garcia-Fuentes, E; Rodriguez-Pacheco, F – 2021
Characterizing Highly Cited Papers in Mass Cytometry through H-Classics.
Di Zeo-Sanchez, DE; Sanchez-Nunez, P; Stephens, C; Lucena, MI – 2021
Overview of Causality Assessment for Drug-Induced Liver Injury (DILI) in Clinical Trials
Hey-Hadavi, J; Seekins, D; Palmer, M; Coffey, D; Caminis, J; Abdullaev, S; Patwardhan, M; Tyler, H; Raheja, R; Stanley, AM; Pineda-Salgado, L; Bourdet, DL; Andrade, RJ; Hayashi, PH; Dimick-Santos, L; Rockey, DC; Estilo, A – 2021
Clinical Characteristics and Outcome of Drug-Induced Liver Injury in the Older Patients: From the Young-Old to the Oldest-Old.
Weersink, RA; Alvarez-Alvarez, I; Medina-Caliz, I; Sanabria-Cabrera, J; Robles-Diaz, M; Ortega-Alonso, A; Garcia-Cortes, M; Bonilla, E; Niu, H; Soriano, G; Jimenez-Perez, M; Hallal, H; Blanco, S; Kaplowitz, N; Lucena, MI; Andrade, RJ – 2021
Oxidative Stress in Drug-Induced Liver Injury (DILI): From Mechanisms to Biomarkers for Use in Clinical Practice
Villanueva-Paz, M; Moran, L; Lopez-Alcantara, N; Freixo, C; Andrade, RJ; Lucena, MI; Cubero, FJ – 2021
Combination of Tocilizumab and Steroids to Improve Mortality in Patients with Severe COVID-19 Infection: A Spanish, Multicenter, Cohort Study.
Ruiz-Antoran, Belen; Sancho-Lopez, Aranzazu; Torres, Ferran; Moreno-Torres, Victor; de Pablo-Lopez, Itziar; Garcia-Lopez, Paulina; Abad-Santos, Francisco; Rosso-Fernandez, Clara M; Aldea-Perona, Ana; Montane, Eva; Aparicio-Hernandez, Ruth M; Llop-Rius, Roser; Pedros, Consuelo; Gijon, Paloma; Hernandez-Carballo, Carolina; Pedrosa-Martinez, Maria J; Rodriguez-Jimenez, Consuelo; Prada-Ramallal, Guillermo; Cabrera-Garcia, Lourdes; Aguilar-Garcia, Josefa A; Sanjuan-Jimenez, Rocio; Ortiz-Barraza, Evelyn I; Sanchez-Chica, Enrique; Fernandez-Cruz, Ana – 2021
Oxidized LDL Increase the Proinflammatory Profile of Human Visceral Adipocytes Produced by Hypoxia
Santiago-Fernandez, C; Martin-Reyes, F; Tome, M; Gutierrez-Repiso, C; Fernandez-Garcia, D; Ocana-Wilhelmi, L; Rivas-Becerra, J; Tatzber, F; Pursch, E; Tinahones, FJ; Garcia-Fuentes, E; Garrido-Sanchez, L – 2021
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry.
Stephens, C; Robles-Diaz, M; Medina-Caliz, I; Garcia-Cortes, M; Ortega-Alonso, A; Sanabria-Cabrera, J; Gonzalez-Jimenez, A; Alvarez-Alvarez, I; Slim, M; Jimenez-Perez, M; Gonzalez-Grande, R; Fernandez, MC; Casado, M; Soriano, G; Roman, E; Hallal, H; Romero-Gomez, M; Castiella, A; Conde, I; Prieto, M; Moreno-Planas, JM; Giraldez, A; Moreno-Sanfiel, JM; Kaplowitz, N; Lucena, MI; Andrade, RJ – 2021
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Raúl J. Andrade Bellido
Email: andrade@uma.es
ORCID
SCOPUS
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Co-investigator in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Eduardo García Fuentes
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Co-Investigadora ResponsableSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Mercedes Robles Díaz
Email: mrobles@uma.es
ORCID
SCOPUS
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Investigador/a SéniorSerán aquellos que tengan una actividad investigadora de al menos 5 años en la etapa posdoctoral. Estos investigadores estarán adscritos a un Grupo de Investigación liderado por un Investigador Responsable. Las funciones serán las que le tenga asignadas su IR.
Pueden liderar una línea de investigación de alguno de los grupos de investigación del Instituto, con financiación competitiva propia, y con potencial para llegar a convertirse responsable de un grupo de investigación.
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Investigador/a Asistencial Colaborador/aSerá Investigador Asistencial Colaborador el Investigador que no reúne la consideración de Investigador Posdoctoral. Estarán adscritos a un Grupo de Investigación liderado por un IR. Las funciones serán las que le tenga asignada su IR.
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Investigadores/as posdoctorales y/o juniorEsta etapa posdoctoral estará restringida a Investigadores del Instituto que tengan el título doctor y no contemplados en los perfiles posteriores. Durante su etapa posdoctoral pueden llegar a liderar proyectos de I+D+i como Investigadores Principales, aunque aún no hayan establecido un nivel significativo de independencia. Además, pueden tener actividades de docencia y/o asistencial más allá de su trabajo de investigación.
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Investigadores/as predoctorales y/o en formación
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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Technical staff
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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