Hepatogastroenterology, Pharmacology, and Translational Clinical Therapeutics
Lines of Research
02.Etiopathogenesis and new treatments in inflammatory bowel disease
03.Etiopathogenesis, clinical course, and non-invasive diagnosis of non-alcoholic fatty liver disease
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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Combination of Tocilizumab and Steroids to Improve Mortality in Patients with Severe COVID-19 Infection: A Spanish, Multicenter, Cohort Study.
Ruiz-Antoran, Belen; Sancho-Lopez, Aranzazu; Torres, Ferran; Moreno-Torres, Victor; de Pablo-Lopez, Itziar; Garcia-Lopez, Paulina; Abad-Santos, Francisco; Rosso-Fernandez, Clara M; Aldea-Perona, Ana; Montane, Eva; Aparicio-Hernandez, Ruth M; Llop-Rius, Roser; Pedros, Consuelo; Gijon, Paloma; Hernandez-Carballo, Carolina; Pedrosa-Martinez, Maria J; Rodriguez-Jimenez, Consuelo; Prada-Ramallal, Guillermo; Cabrera-Garcia, Lourdes; Aguilar-Garcia, Josefa A; Sanjuan-Jimenez, Rocio; Ortiz-Barraza, Evelyn I; Sanchez-Chica, Enrique; Fernandez-Cruz, Ana – 2021
Oxidized LDL Increase the Proinflammatory Profile of Human Visceral Adipocytes Produced by Hypoxia
Santiago-Fernandez, C; Martin-Reyes, F; Tome, M; Gutierrez-Repiso, C; Fernandez-Garcia, D; Ocana-Wilhelmi, L; Rivas-Becerra, J; Tatzber, F; Pursch, E; Tinahones, FJ; Garcia-Fuentes, E; Garrido-Sanchez, L – 2021
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry.
Stephens, C; Robles-Diaz, M; Medina-Caliz, I; Garcia-Cortes, M; Ortega-Alonso, A; Sanabria-Cabrera, J; Gonzalez-Jimenez, A; Alvarez-Alvarez, I; Slim, M; Jimenez-Perez, M; Gonzalez-Grande, R; Fernandez, MC; Casado, M; Soriano, G; Roman, E; Hallal, H; Romero-Gomez, M; Castiella, A; Conde, I; Prieto, M; Moreno-Planas, JM; Giraldez, A; Moreno-Sanfiel, JM; Kaplowitz, N; Lucena, MI; Andrade, RJ – 2021
Immune-Mediated Drug-Induced Liver Injury: Immunogenetics and Experimental Models
Gerussi, A; Natalini, A; Antonangeli, F; Mancuso, C; Agostinetto, E; Barisani, D; Di Rosa, F; Andrade, R; Invernizzi, P – 2021
Preclinical models of idiosyncratic drug-induced liver injury (iDILI): Moving towards prediction
Segovia-Zafra, A; Zeo-Sanchez, DED; Lopez-Gomez, C; Perez-Valdes, Z; Garcia-Fuentes, E; Andrade, RJ; Lucena, MI; Villanueva-Paz, M – 2021
Consensus Guidelines: Best Practices for Detection, Assessment and Management of Suspected Acute Drug-Induced Liver Injury During Clinical Trials in Adults with Chronic Viral Hepatitis and Adults with Cirrhosis Secondary to Hepatitis B, C and Nonalcoholic Steatohepatitis
Treem, WR; Palmer, M; Lonjon-Domanec, I; Seekins, D; Dimick-Santos, L; Avigan, MI; Marcinak, JF; Dash, A; Regev, A; Maller, E; Patwardhan, M; Lewis, JH; Rockey, DC; Di Bisceglie, AM; Freston, JW; Andrade, RJ; Chalasani, N – 2021
Incidence and prevalence of acute hepatitis E virus infection in patients with suspected Drug-Induced Liver Injury in the Spanish DILI Registry,
Sanabria-Cabrera, J; Sanjuan-Jimenez, R; Clavijo, E; Medina-Caliz, I; Gonzalez-Jimenez, A; Garcia-Cortes, M; Ortega-Alonso, A; Jimenez-Perez, M; Gonzalez-Grande, R; Stephens, C; Robles-Diaz, M; Lucena, MI; Andrade, RJ – 2021
Prevention and management of idiosyncratic drug-induced liver injury: Systematic review and meta-analysis of randomised clinical trials
Niu, H; Sanabria-Cabrera, J; Alvarez-Alvarez, I; Robles-Diaz, M; Stankeviciute, S; Aithal, GP; Bjornsson, ES; Andrade, RJ; Lucena, MI – 2021
Critical Review of Gaps in the Diagnosis and Management of Drug-Induced Liver Injury Associated with Severe Cutaneous Adverse Reactions
Villanueva-Paz, M; Niu, H; Segovia-Zafra, A; Medina-Caliz, I; Sanabria-Cabrera, J; Lucena, MI; Andrade, RJ; Alvarez-Alvarez, I – 2021
Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study
Chaparro, M; Garre, A; Ortiz, AN; Palomares, MTDL; Rodriguez, C; Riestra, S; Vela, M; Benitez, JM; Salgado, EF; Rodriguez, ES; Hernandez, V; Ferreiro-Iglesias, R; Diaz, AP; Barrio, J; Huguet, JM; Sicilia, B; Martin-Arranz, MD; Calvet, X; Ginard, D; Alonso-Abreu, I; Fernandez-Salazar, L; Trastoy, PV; Rivero, M; Vera-Mendoza, I; Vega, P; Navarro, P; Sierra, M; Cabriada, JL; Aguas, M; Vicente, R; Navarro-Llavat, M; Echarri, A; Gomollon, F; del Rio, EG; Pinero, C; Casanova, MJ; Spicakova, K; de Zarate, JO; Cortes, ET; Gutierrez, A; Alonso-Galan, H; Hernandez-Martinez, A; Marrero, JM; Poyatos, RL; Calafat, M; Romero, LM; Robledo, P; Bosch, O; Jimenez, N; Comas, ME; Duque, JM; Coronel, AMF; Sampedro, MJ; Abizanda, ES; Martinez, BH; Pozzati, L; Rosaenz, HF; Suarez, BC; Serrano, PL; Lucendo, AJ; Vicente, MM; Bermejo, F; Palanca, JJR; Menacho, M; Carmona, A; Camargo, R; Alsina, ST; Maroto, N; de la Puerta, JN; Castro, E; Marin-Jimenez, I; Botella, B; Sapina, A; Cruz, N; Forcelledo, JLF; Bouhmidi, A; Castano-Milla, C; Opio, V; Nicolas, I; Kutz, M; Bechiarelli, AA; Gordillo, J; Ber, Y; Dominguez, YT; Duran, MTN; Mondejar, SR; Martinez-Cerezo, FJ; Kolle, L; Sabat, M; Ledezma, C; Iyo, E; Roncero, O; Irisarri, R; Lluis, L; Gomez, IB; Zapata, EM; Alcala, MJ; Pascual, CM; Montealegre, M; Mata, L; Monrobel, A; Camba, AH; Hernandez, L; Tejada, M; Mir, A; Galve, ML; Soler, M; Hervias, D; Gomez-Valero, JA; Barreiro-de Acosta, M; Rodriguez-Artalejo, F; Garcia-Esquinas, E; Gisbert, JP – 2021
Profile of herbal and dietary supplements induced liver injury in Latin America: A systematic review of published reports
Santos, G; Gasca, J; Parana, R; Nunes, V; Schinnoni, M; Medina-Caliz, I; Cabello, MR; Lucena, MI; Andrade, RJ – 2021
Definite and indeterminate nonalcoholic steatohepatitis share similar clinical features and prognosis: A longitudinal study of 1893 biopsy-proven nonalcoholic fatty liver disease subjects
Ampuero, J; Aller, R; Gallego-Duran, R; Crespo, J; Abad, J; Gonzalez-Rodriguez, A; Gomez-Camarero, J; Caballeria, J; Lo Iacono, O; Ibanez, L; Garcia-Samaniego, J; Martin-Mateos, R; Frances, R; Fernandez-Rodriguez, C; Diago, M; Soriano, G; Andrade, RJ; Latorre, R; Jorquera, F; Morillas, RM; Escudero, D; Estevez, P; Hernandez-Guerra, M; Augustin, S; Pareja-Megia, MJ; Banales, JM; Aspichueta, P; Benlloch, S; Rosales, JM; Salmeron, J; Turnes, J; Romero-Gomez, M – 2021
Influence of Factors Altering Gastric Microbiota on Bariatric Surgery Metabolic Outcomes
Gutierrez-Repiso, C; Moreno-Indias, I; Martin-Nunez, GM; Ho-Plagaro, A; Ocana-Wilhelmi, L; Garcia, DF; Marin, MG; Moreno-Ruiz, FJ; Garcia-Fuentes, E; Tinahones, FJ – 2021
Promoting exercise, reducing sedentarism or both for diabetes prevention: The Seguimiento Universidad De Navarra (SUN) cohort
Llavero-Valero, M; San Martin, JE; Martinez-Gonzalez, MA; Alvarez-Mon, MA; Alvarez-Alvarez, I; Martinez-Gonzalez, J; Bes-Rastrollo, M – 2021
Drug properties and host factors contribute to biochemical presentation of drug-induced liver injury: a prediction model from a machine learning approach
Gonzalez-Jimenez, A; Suzuki, A; Chen, MJ; Ashby, K; Alvarez-Alvarez, I; Andrade, RJ; Lucena, MI – 2021
Late presentation of chronic HBV and HCV patients seeking first time specialist care in Spain: a 2-year registry review
Picchio, CA; Lens, S; Hernandez-Guerra, M; Arenas, J; Andrade, RJ; Crespo, J; Garcia-Samaniego, J; Romero-Gomez, M; Turnes, J; Calleja, JL; Simon, MA; White, TM; Riveiro-Barciela, M; Pocurull, A; Morales-Arraez, D; Gomez, A; Buti, M; Lazarus, JV – 2021
Role of Ursodeoxycholic Acid in Treating and Preventing Idiosyncratic Drug-Induced Liver Injury. A Systematic Review
Robles-Diaz, M; Nezic, L; Vujic-Aleksic, V; Bjornsson, ES – 2021
Elevated bilirubin, alkaline phosphatase at onset, and drug metabolism are associated with prolonged recovery from DILI
Ashby, K; Zhuang, W; Gonzalez-Jimenez, A; Alvarez-Alvarez, I; Lucena, MI; Andrade, RJ; Aithal, GP; Suzuki, A; Chen, MJ – 2021
Listeria monocytogenes dissemination in farming and primary production: Sources, shedding and control measures
Rodriguez, C; Taminiau, B; Garcia-Fuentes, E; Daube, G; Korsak, N – 2021
Serious liver injury induced by Nimesulide: an international collaborative study
Bessone, F; Hernandez, N; Mendizabal, M; Ridruejo, E; Gualano, G; Fassio, E; Peralta, M; Fainboim, H; Anders, M; Tanno, H; Tanno, F; Parana, R; Medina-Caliz, I; Robles-Diaz, M; Alvarez-Alvarez, I; Niu, H; Stephens, C; Colombato, L; Arrese, M; Reggiardo, MV; Ono, SK; Carrilho, F; Lucena, MI; Andrade, RJ – 2021
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Raúl J. Andrade Bellido
Email: andrade@uma.es
ORCID
SCOPUS
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Co-investigator in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Eduardo García Fuentes
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Co-Investigadora ResponsableSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Mercedes Robles Díaz
Email: mrobles@uma.es
ORCID
SCOPUS
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Investigador/a SéniorSerán aquellos que tengan una actividad investigadora de al menos 5 años en la etapa posdoctoral. Estos investigadores estarán adscritos a un Grupo de Investigación liderado por un Investigador Responsable. Las funciones serán las que le tenga asignadas su IR.
Pueden liderar una línea de investigación de alguno de los grupos de investigación del Instituto, con financiación competitiva propia, y con potencial para llegar a convertirse responsable de un grupo de investigación.
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Investigador/a Asistencial Colaborador/aSerá Investigador Asistencial Colaborador el Investigador que no reúne la consideración de Investigador Posdoctoral. Estarán adscritos a un Grupo de Investigación liderado por un IR. Las funciones serán las que le tenga asignada su IR.
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Investigadores/as posdoctorales y/o juniorEsta etapa posdoctoral estará restringida a Investigadores del Instituto que tengan el título doctor y no contemplados en los perfiles posteriores. Durante su etapa posdoctoral pueden llegar a liderar proyectos de I+D+i como Investigadores Principales, aunque aún no hayan establecido un nivel significativo de independencia. Además, pueden tener actividades de docencia y/o asistencial más allá de su trabajo de investigación.
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Investigadores/as predoctorales y/o en formación
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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Technical staff
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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