Immune response to viral infections
Lines of Research
Estudio de la respuesta inmune frente a infecciones virales y los mecanismos de inmunopatología viral
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Estudio de virus de alta relevancia biomédica:
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Coronavirus (SARS-CoV-1, SARS-CoV-2, NL63-CoV)
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Virus de la inmunodeficiencia humana (VIH)
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Virus de la gripe
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- Research Projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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Development of a structural epitope mimic: an idiotypic approach to HCV vaccine design
Immunogene expression analysis in betanodavirus infected-Senegalese sole using an OpenArray® platform
Gémez-Mata, J; Labella, AM; Bandín, I; Borrego, JJ; García-Rosado, E – 2021
Resilient SARS-CoV-2 diagnostics workflows including viral heat inactivation
Lista, MJ; Matos, PM; Maguire, TJA; Poulton, K; Ortiz-Zapater, E; Page, R; Sertkaya, H; Ortega-Prieto, AM; Scourfield, E; O’Byrne, AM; Bouton, C; Dickenson, RE; Ficarelli, M; Jimenez-Guardeño, JM; Howard, M; Betancor, G; Galao, RP; Pickering, S; Signell, AW; Wilson, H; Cliff, P; Ik, MTK; Patel, A; MacMahon, E; Cunningham, E; Doores, K; Agromayor, M; Martin-Serrano, J; Perucha, E; Mischo, HE; Shankar-Hari, M; Batra, R; Edgeworth, J; Zuckerman, M; Malim, MH; Neil, S; Martinez-Nunez, RT – 2021
Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia
Braga, L; Ali, H; Secco, I; Chiavacci, E; Neves, G; Goldhill, D; Penn, R; Jimenez-Guardeño, JM; Ortega-Prieto, AM; Bussani, R; Cannatà, A; Rizzari, G; Collesi, C; Schneider, E; Arosio, D; Shah, AM; Barclay, WS; Malim, MH; Burrone, J; Giacca, M – 2021
Factors associated with the number of drugs in darunavir/cobicistat regimens-
Martinez, E; Negredo, E; Knobel, H; Ocampo, A; Sanz, J; Garcia-Fraile, L; Martin-Carbonero, L; Lozano, F; Gonzalez-Domenech, CM; Gutierrez, M; Montero, M; Boix, V; Payeras, A; Torralba, M; Gonzalez-Cordon, A; Moreno, A; Alejos, B; Perez-Elias, MJ – 2020
Virulence properties of three new Photobacterium species affecting cultured fish
Labella, AM; Rosado, JJ; Balado, M; Lemos, ML; Borrego, JJ – 2020
Fish and Shellfish Pathogens
Balcazar, JL; Borrego, JJ – 2020
Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans
Seow, J; Graham, C; Merrick, B; Acors, S; Pickering, S; Steel, KJA; Hemmings, O; O’Byrne, A; Kouphou, N; Galao, RP; Betancor, G; Wilson, HD; Signell, AW; Winstone, H; Kerridge, C; Huettner, I; Jimenez-Guardeño, JM; Lista, MJ; Temperton, N; Snell, LB; Bisnauthsing, K; Moore, A; Green, A; Martinez, L; Stokes, B; Honey, J; Izquierdo-Barras, A; Arbane, G; Patel, A; Tan, MKI; O’Connell, L; O’Hara, G; MacMahon, E; Douthwaite, S; Nebbia, G; Batra, R; Martinez-Nunez, R; Shankar-Hari, M; Edgeworth, JD; Neil, SJD; Malim, MH; Doores, KJ – 2020
Heritability Estimates and Genetic Correlation for Growth Traits and LCDV Susceptibility in Gilthead Sea Bream (Sparus aurata)
Carballo, C; Shin, HS; Berbel, C; Zamorano, MJ; Borrego, JJ; Armero, E; Afonso, JM; Manchado, M – 2020
High Prevalence of Sequences Included in Transmission Clusters Within Newly Diagnosed HIV-1 Patients in Southern Spain (2004-2015)-
González-Domenech, CM; Sena-Corrales, G; Viciana-Ramos, I; Palacios-Muñoz, R; Mora-Navas, L; Clavijo-Frutos, E; Santos-González, J – 2020
Human Organs-on-Chips for Virology
Tang, HQ; Abouleila, Y; Si, LL; Ortega-Prieto, AM; Mummery, CL; Ingber, DE; Mashaghi, A – 2020
Hypoxic gene expression in chronic hepatitis B virus infected patients is not observed in state-of-the-art in vitro and mouse infection models
Liu, PJ; Harris, JM; Marchi, E; D’Arienzo, V; Michler, T; Wing, PAC; Magri, A; Ortega-Prieto, AM; van de Klundert, M; Wettengel, J; Durantel, D; Dorner, M; Klenerman, P; Protzer, U; Giotis, ES; McKeating, JA – 2020
Nanostructured recombinant protein particles raise specific antibodies against the nodavirus NNV coat protein in sole
Thwaite, R; Berbel, C; Aparicio, M; Torrealba, D; Pesarrodona, M; Villaverde, A; Borrego, JJ; Manchado, M; Roher, N – 2020
Immune gene expression in gilthead seabream (Sparus aurata) after Lymphocystis disease virus (LCDV-Sa) challenge resulting in asymptomatic infection
Leiva-Rebollo, R; Labella, AM; Borrego, JJ; Castro, D – 2020
Persistence of Lymphocystis Disease Virus (LCDV) in Seawater
Leiva-Rebollo, R; Labella, AM; Valverde, EJ; Castro, D; Borrego, JJ – 2020
Differential immunogene expression profile of European sea bass (Dicentrarchus labrax, L.) in response to highly and low virulent NNV
Moreno, P; Gemez-Mata, J; Garcia-Rosado, E; Bejar, J; Labella, AM; Souto, S; Alonso, MC – 2020
The GTPase Domain of MX2 Interacts with the HIV-1 Capsid, Enabling Its Short Isoform to Moderate Antiviral Restriction
Betancor, G; Dicks, MDJ; Jimenez-Guardeño, JM; Ali, NH; Apolonia, L; Malim, MH – 2019
Kinetics of Early Innate Immune Activation during HIV-1 Infection of Humanized Mice
Skelton, JK; Ortega-Prieto, AM; Kaye, S; Jimenez-Guardeño, JM; Turner, J; Malim, MH; Towers, GJ; Dorner, M – 2019
Feed and immersion challenges with lymphocystis disease virus (LCDV) reveals specific mechanisms for horizontal transmission and immune response in senegalese sole post-larvae
Carballo, C; Ortiz-Delgado, JB; Berbel, C; Castro, D; Borrego, JJ; Sarasquete, C; Manchado, M – 2019
Liver-on-a-Chip Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
Ortega-Prieto, AM; Skelton, JK; Cherry, C; Briones-Orta, MA; Hateley, CA; Dorner, M – 2019
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
Juan José Borrego García
Email: jjborrego@uma.es
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Co-investigator in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

José Manuel Jiménez Guardeño
Email: jose.jimenez@uma.es
Ana María Ortega Prieto
Email: ana.ortega@uma.es
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Investigador/a SéniorSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigador/a Asistencial Colaborador/aSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigadores/as posdoctorales y/o juniorSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigadores/as predoctorales y/o en formaciónSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Technical staffSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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