Skeleton Biomedicine Laboratory
Lines of Research
01.Tissue regeneration. Skeletal tissue engineering. Therapeutic osteogenesis and chondrogenesis
02.Design and production of biomolecules and biomaterials for regenerative medicine of the musculoskeletal system
03.Cellular therapy based on Mesenchymal Stem Cells (MSC)
04.Production and characterization of the MSC secretome. Therapeutic possibilities in inflammatory pathologies and immunomeasurements
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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4-PBA Treatment Improves Bone Phenotypes in the Aga2 Mouse Model of Osteogenesis Imperfecta
Duran, I; Zieba, J; Csukasi, F; Martin, JH; Wachtell, D; Barad, M; Dawson, B; Fafilek, B; Jacobsen, CM; Ambrose, CG; Cohn, DH; Krejci, P; Lee, BH; Krakow, D – 2022
Suicide gene therapy by canine mesenchymal stem cell transduced with thymidine kinase in a u-87 glioblastoma murine model: Secretory profile and antitumor activity
Villatoro, AJ; Alcoholado, C; Martin-Astorga, MD; Rubio, N; Blanco, J; Garrido, CP; Becerra, J – 2022
Traditional Medicinal Plants as a Source of Inspiration for Osteosarcoma Therapy
Kazantseva, L; Becerra, J; Santos-Ruiz, L – 2022
Inflammation, a common mechanism in frailty and COVID19, and stem cells as a therapeutic approach
Becerra, J; Duran, I – 2021
Proteomic Analysis of the Secretome and Exosomes of Feline Adipose-Derived Mesenchymal Stem Cells
Villatoro, AJ; Martin-Astorga, MD; Alcoholado, C; Sanchez-Martin, MD; Becerra, J – 2021
Sponge-like processed D-periodic self-assembled atelocollagen supports bone formation in vivo
Borrego-Gonzalez, S; Rico-Llanos, G; Becerra, J; Diaz-Cuenca, A; Visser, R – 2021
Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate.
Vega-Granados, K; Cruz-Reyes, J; Horta-Marron, JF; Mari-Beffa, M; Diaz-Rubio, L; Cordova-Guerrero, I; Chavez-Velasco, D; Ocana, MC; Medina, MA; Romero-Sanchez, LB – 2021
The Effect of Pore Directionality of Collagen Scaffolds on Cell Differentiation and In Vivo Osteogenesis
Moncayo-Donoso, M; Rico-Llanos, GA; Garzon-Alvarado, DA; Becerra, J; Visser, R; Fontanilla, MR – 2021
Zebrafish Models for Human Skeletal Disorders
Mari-Beffa, M; Mesa-Roman, ABB; Duran, I – 2021
Altered Proteomic Profile of Adipose Tissue-Derived Mesenchymal Stem Cell Exosomes from Cats with Severe Chronic Gingivostomatitis
Villatoro, AJ; Martin-Astorga, MD; Alcoholado, C; Cardenas, C; Farinas, F; Becerra, J; Visser, R – 2021
An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice
Kimura, T; Bosakova, M; Nonaka, Y; Hruba, E; Yasuda, K; Futakawa, S; Kubota, T; Fafilek, B; Gregor, T; Abraham, SP; Gomolkova, R; Belaskova, S; Pesl, M; Csukasi, F; Duran, I; Fujiwara, M; Kavkova, M; Zikmund, T; Kaiser, J; Buchtova, M; Krakow, D; Nakamura, Y; Ozono, K; Krejci, P – 2021
Collagen Type I Biomaterials as Scaffolds for Bone Tissue Engineering
Rico-Llanos, GA; Borrego-Gonzalez, S; Moncayo-Donoso, M; Becerra, J; Visser, R – 2021
DEPTOR in Skeletal Development and Diseases
Perez-Tejeiro, JM; Csukasi, F – 2021
Design, Synthesis, and Biological Evaluation of Hybrid Glypromate Analogues Using 2-Azanorbornane as a Prolyl and Pipecolyl Surrogate
Sampaio-Dias, IE; Santejo, M; Silva-Reis, SC; Liz, MA; Alcoholado, C; Algarra, M; Garcia-Mera, X; Rodriguez-Borges, JE – 2021
Discovery of New Potent Positive Allosteric Modulators of Dopamine D-2 Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide
Sampaio-Dias, IE; Reis-Mendes, A; Costa, VM; Garcia-Mera, X; Brea, J; Loza, MI; Pires-Lima, BL; Alcoholado, C; Algarra, M; Rodriguez-Borges, JE – 2021
IIIG9 inhibition in adult ependymal cells changes adherens junctions structure and induces cellular detachment
Baeza, V; Cifuentes, M; Martinez, F; Ramirez, E; Nualart, F; Ferrada, L; Oviedo, MJ; De Lima, I; Troncoso, N; Saldivia, N; Salazar, K – 2021
Dehydroascorbic acid, the oxidized form of vitamin C, improves renal histology and function in old mice
Forman, K; Martinez, F; Cifuentes, M; Fernandez, M; Bertinat, R; Torres, P; Salazar, K; Godoy, A; Nualart, F – 2020
Dendritic Scaffold onto Titanium Implants. A Versatile Strategy Increasing Biocompatibility.
Molina, N; Gonzalez, A; Monopoli, D; Mentado, B; Becerra, J; Santos-Ruiz, L; Vida, Y; Perez-Inestrosa, E – 2020
Fasentin diminishes endothelial cell proliferation, differentiation and invasion in a glucose metabolism-independent manner
Ocana, MC; Poveda, BM; Mari-Beffa, M; Quesada, AR; Medina, MA – 2020
LPA(1) receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance
Moreno-Fernandez, RD; Rosell-Valle, C; Bacq, A; Zanoletti, O; Cifuentes, M; Perez-Martin, M; Gavito, AL; Garcia-Fernandez, MI; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Sandi, C; Pedraza, C – 2020
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

Iván Durán Jiménez
Email: ijduran@uma.es
ORCID
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Co-Investigador/a ResponsableSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

Fabiana Csukasi
Email: fabiana@uma.es
ORCID
SCOPUS
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Investigador/a SéniorSerán aquellos que tengan una actividad investigadora de al menos 5 años en la etapa posdoctoral. Estos investigadores estarán adscritos a un Grupo de Investigación liderado por un Investigador Responsable. Las funciones serán las que le tenga asignadas su IR.
Pueden liderar una línea de investigación de alguno de los grupos de investigación del Instituto, con financiación competitiva propia, y con potencial para llegar a convertirse responsable de un grupo de investigación.
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Investigadores/as posdoctorales y/o juniorEsta etapa posdoctoral estará restringida a Investigadores del Instituto que tengan el título doctor y no contemplados en los perfiles posteriores. Durante su etapa posdoctoral pueden llegar a liderar proyectos de I+D+i como Investigadores Principales, aunque aún no hayan establecido un nivel significativo de independencia. Además, pueden tener actividades de docencia y/o asistencial más allá de su trabajo de investigación.
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Investigadores/as predoctorales y/o en formación
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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Technical staffSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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