Skeleton Biomedicine Laboratory
Lines of Research
01.Tissue regeneration. Skeletal tissue engineering. Therapeutic osteogenesis and chondrogenesis
02.Design and production of biomolecules and biomaterials for regenerative medicine of the musculoskeletal system
03.Cellular therapy based on Mesenchymal Stem Cells (MSC)
04.Production and characterization of the MSC secretome. Therapeutic possibilities in inflammatory pathologies and immunomeasurements
- Research projects
- Clinical studies
- Scientific Publications
- Technological Offers
- Industrial property records
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An RNA aptamer restores defective bone growth in FGFR3-related skeletal dysplasia in mice
Kimura, T; Bosakova, M; Nonaka, Y; Hruba, E; Yasuda, K; Futakawa, S; Kubota, T; Fafilek, B; Gregor, T; Abraham, SP; Gomolkova, R; Belaskova, S; Pesl, M; Csukasi, F; Duran, I; Fujiwara, M; Kavkova, M; Zikmund, T; Kaiser, J; Buchtova, M; Krakow, D; Nakamura, Y; Ozono, K; Krejci, P – 2021
Collagen Type I Biomaterials as Scaffolds for Bone Tissue Engineering
Rico-Llanos, GA; Borrego-Gonzalez, S; Moncayo-Donoso, M; Becerra, J; Visser, R – 2021
DEPTOR in Skeletal Development and Diseases
Perez-Tejeiro, JM; Csukasi, F – 2021
Design, Synthesis, and Biological Evaluation of Hybrid Glypromate Analogues Using 2-Azanorbornane as a Prolyl and Pipecolyl Surrogate
Sampaio-Dias, IE; Santejo, M; Silva-Reis, SC; Liz, MA; Alcoholado, C; Algarra, M; Garcia-Mera, X; Rodriguez-Borges, JE – 2021
Discovery of New Potent Positive Allosteric Modulators of Dopamine D-2 Receptors: Insights into the Bioisosteric Replacement of Proline to 3-Furoic Acid in the Melanostatin Neuropeptide
Sampaio-Dias, IE; Reis-Mendes, A; Costa, VM; Garcia-Mera, X; Brea, J; Loza, MI; Pires-Lima, BL; Alcoholado, C; Algarra, M; Rodriguez-Borges, JE – 2021
IIIG9 inhibition in adult ependymal cells changes adherens junctions structure and induces cellular detachment
Baeza, V; Cifuentes, M; Martinez, F; Ramirez, E; Nualart, F; Ferrada, L; Oviedo, MJ; De Lima, I; Troncoso, N; Saldivia, N; Salazar, K – 2021
Inflammation, a common mechanism in frailty and COVID19, and stem cells as a therapeutic approach
Becerra, J; Duran, I – 2021
Proteomic Analysis of the Secretome and Exosomes of Feline Adipose-Derived Mesenchymal Stem Cells
Villatoro, AJ; Martin-Astorga, MD; Alcoholado, C; Sanchez-Martin, MD; Becerra, J – 2021
Sponge-like processed D-periodic self-assembled atelocollagen supports bone formation in vivo
Borrego-Gonzalez, S; Rico-Llanos, G; Becerra, J; Diaz-Cuenca, A; Visser, R – 2021
Synthesis, characterization and biological evaluation of octyltrimethylammonium tetrathiotungstate.
Vega-Granados, K; Cruz-Reyes, J; Horta-Marron, JF; Mari-Beffa, M; Diaz-Rubio, L; Cordova-Guerrero, I; Chavez-Velasco, D; Ocana, MC; Medina, MA; Romero-Sanchez, LB – 2021
RGD-Dendrimer-Poly(L-lactic) Acid Nanopatterned Substrates for the Early Chondrogenesis of Human Mesenchymal Stromal Cells Derived from Osteoarthritic and Healthy Donors.
Rodriguez-Pereira, C; Lagunas, A; Casanellas, I; Vida, Y; Perez-Inestrosa, E; Andrades, JA; Becerra, J; Samitier, J; Blanco, FJ; Magalhaes, J – 2020
The Janus Role of Adhesion in Chondrogenesis.
Casanellas, I; Lagunas, A; Vida, Y; Perez-Inestrosa, E; Andrades, JA; Becerra, J; Samitier, J – 2020
3D Biomimetic Porous Titanium (Ti6Al4V ELI) Scaffolds for Large Bone Critical Defect Reconstruction: An Experimental Study in Sheep
Crovace, AM; Lacitignola, L; Forleo, DM; Staffieri, F; Francioso, E; Di Meo, A; Becerra, J; Crovace, A; Santos-Ruiz, L – 2020
Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia
Barad, M; Csukasi, F; Bosakova, M; Martin, JH; Zhang, WJ; Taylor, SP; Lachman, RS; Zieba, J; Bamshad, M; Nickerson, D; Chong, JX; Cohn, DH; Krejci, P; Krakow, D; Duran, I – 2020
Canine colostrum exosomes: characterization and influence on the canine mesenchymal stem cell secretory profile and fibroblast anti-oxidative capacity
Villatoro, AJ; Martin-Astorga, MD; Alcoholado, C; Becerra, J – 2020
Characterization of the secretory profile and exosomes of limbal stem cells in the canine species
Villatoro, AJ; Alcoholado, C; Martin-Astorga, MD; Rico, G; Fernandez, V; Becerra, J – 2020
Dehydroascorbic acid, the oxidized form of vitamin C, improves renal histology and function in old mice
Forman, K; Martinez, F; Cifuentes, M; Fernandez, M; Bertinat, R; Torres, P; Salazar, K; Godoy, A; Nualart, F – 2020
Dendritic Scaffold onto Titanium Implants. A Versatile Strategy Increasing Biocompatibility.
Molina, N; Gonzalez, A; Monopoli, D; Mentado, B; Becerra, J; Santos-Ruiz, L; Vida, Y; Perez-Inestrosa, E – 2020
Fasentin diminishes endothelial cell proliferation, differentiation and invasion in a glucose metabolism-independent manner
Ocana, MC; Poveda, BM; Mari-Beffa, M; Quesada, AR; Medina, MA – 2020
LPA(1) receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance
Moreno-Fernandez, RD; Rosell-Valle, C; Bacq, A; Zanoletti, O; Cifuentes, M; Perez-Martin, M; Gavito, AL; Garcia-Fernandez, MI; Estivill-Torrus, G; de Fonseca, FR; Santin, LJ; Sandi, C; Pedraza, C – 2020
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

Iván Durán Jiménez
Email: ijduran@uma.es
ORCID
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Co-Investigador/a ResponsableSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.

Fabiana Csukasi
Email: fabiana@uma.es
ORCID
SCOPUS
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Investigador/a SéniorSerán aquellos que tengan una actividad investigadora de al menos 5 años en la etapa posdoctoral. Estos investigadores estarán adscritos a un Grupo de Investigación liderado por un Investigador Responsable. Las funciones serán las que le tenga asignadas su IR.
Pueden liderar una línea de investigación de alguno de los grupos de investigación del Instituto, con financiación competitiva propia, y con potencial para llegar a convertirse responsable de un grupo de investigación.
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Investigadores/as posdoctorales y/o juniorEsta etapa posdoctoral estará restringida a Investigadores del Instituto que tengan el título doctor y no contemplados en los perfiles posteriores. Durante su etapa posdoctoral pueden llegar a liderar proyectos de I+D+i como Investigadores Principales, aunque aún no hayan establecido un nivel significativo de independencia. Además, pueden tener actividades de docencia y/o asistencial más allá de su trabajo de investigación.
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Investigadores/as predoctorales y/o en formación
Los investigadores predoctorales y/o en formación serán aquellos investigadores que realizan investigaciones bajo supervisión en una línea de investigación orientada a la resolución de problemas de salud. Incluye aquellos investigadores que están cursando un doctorado (incluyendo a los contratados Río Hortega)
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