Investigación Clínica y Traslacional en Cáncer
Lines of Research
01.Investigación clínica-traslacional en cáncer de mama, próstata, ginecológicos digestivo y germinales
02.Investigación traslacional en identificación de marcadores epigenéticos/genéticos de fases tempranas del cáncer
03.Investigación en el uso de nuevas técnicas de diagnóstico (biopsia líquida…) y marcadores
04.Investigación en la relación de la microbiota y el cáncer
05.Investigación en real world data
- Proyectos de investigación
- Estudios clínicos
- Publicaciones científicas
- Ofertas tecnológicas
- Registros de propiedad industrial
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Uterine sarcomas: clinical practice guidelines for diagnosis, treatment, and follow-up, by Spanish group for research on sarcomas (GEIS) – THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY
Perez-Fidalgo, JA; Ortega, E; Ponce, J; Redondo, A; Sevilla, I; Valverde, C; Verdum, JI; de Alava, E; Lopez, MG; Marquina, G; Sebio, A – 2023 – 10.1177/17588359231157645
Development of a functional assessment task in metastatic breast cancer patients: the 30-second lie-to-sit test; – DISABILITY AND REHABILITATION
Cuesta-Vargas, A; Buchan, J; Alba, E; Campos, MI; Roldan-Jimenez, C; Pajares, B – 2023 – 10.1080/09638288.2022.2076937
Multi-Omics Approach Reveals Prebiotic and Potential Antioxidant Effects of Essential Oils from the Mediterranean Diet on Cardiometabolic Disorder Using Humanized Gnotobiotic Mice. – ANTIOXIDANTS
Sánchez-Quintero, MJ; Delgado, J; Chaves, LM; Medina-Vera, D; Murri, M; Becerra-Muñoz, VM; Estévez, M; Crespo-Leiro, MG; López, GP; González-Jiménez, A; Ranea, JAG; Queipo-Ortuño, MI; Plaza-Andrades, I; Rodríguez-Capitán, J; Pavón-Morón, FJ; Jiménez-Navarro, MF – 2023 – 10.3390/antiox12081643
XENERA-1: a randomised double-blind Phase II trial of xentuzumab in combination with everolimus and exemestane versus everolimus and exemestane in patients with hormone receptor-positive/HER2-negative metastatic breast cancer and non-visceral disease – BREAST CANCER RESEARCH
Schmid, Peter; Cortes, Javier; Joaquim, Ana; Janez, Noelia Martinez; Morales, Serafin; Diaz-Redondo, Tamara; Blau, Sibel; Neven, Patrick; Lemieux, Julie; Garcia-Saenz, Jose Angel; Hart, Lowell; Biyukov, Tsvetan; Baktash, Navid; Massey, Dan; Burris, Howard A., III; Rugo, Hope S. – 2023 – 10.1186/s13058-023-01649-w
Development of a Novel NGS Methodology for Ultrasensitive Circulating Tumor DNA Detection as a Tool for Early-Stage Breast Cancer Diagnosis – INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Jimenez-Rodriguez, B; Alba-Bernal, A; Lopez-Lopez, E; Quiros-Ortega, ME; Carbajosa, G; Garrido-Aranda, A; Alvarez, M; Godoy-Ortiz, A; Queipo-Ortuno, MI; Vicioso, L; Diaz-Cordoba, G; Roldan-Diaz, MD; Velasco-Suelto, J; Hernando, C; Bermejo, B; Julve-Parreno, A; Lluch, A; Pascual, J; Comino-Mendez, I; Alba, E – 2023 – 10.3390/ijms24010146
New insights in the targets of action of dimethyl fumarate in endothelial cells: effects on energetic metabolism and serine synthesis in vitro and in vivo, – COMMUNICATIONS BIOLOGY
Ocaña, MC; Bernal, M; Yang, CD; Caro, C; Domínguez, A; Vu, HS; Cárdenas, C; García-Martín, ML; Deberardinis, RJ; Quesada, AR; Martínez-Poveda, B; Medina, MA – 2023 – 10.1038/s42003-023-05443-4
8-Oxoguanine DNA Glycosylase 1 Upregulation as a Risk Factor for Obesity and Colorectal Cancer – INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Pilo, J; García-Flores, LA; Clemente-Postigo, M; Arranz-Salas, I; Alcaide, J; Ramos-Fernandez, M; Lozano, J; Boughanem, H; Kompella, P; Macías-González, M – 2023 – 10.3390/ijms24065488
Development of in vitro and in vivo tools to evaluate the antiangiogenic potential of melatonin to neutralize the angiogenic effects of VEGF and breast cancer cells: CAM assay and 3D endothelial cell spheroids – BIOMEDICINE & PHARMACOTHERAPY
Laborda-Illanes, A; Sanchez-Alcoholado, L; Castellano-Castillo, D; Boutriq, S; Plaza-Andrades, I; Aranega-Martin, L; Peralta-Linero, J; Alba, E; Gonzalez-Gonzalez, A; Queipo-Ortuno, MI – 2023 – 10.1016/j.biopha.2022.114041
Pembrolizumab in Asian patients with microsatellite-instability-high/mismatch-repair-deficient colorectal cancer – CANCER SCIENCE
Yoshino, T; Andre, T; Kim, TW; Yong, WP; Shiu, KK; Jensen, BV; Jensen, LH; Punt, CJA; Smith, D; Garcia-Carbonero, R; Alcaide-Garcia, J; Gibbs, P; De la Fouchardiere, C; Rivera, F; Elez, E; Le, DT; Adachi, N; Fogelman, D; Marinello, P; Diaz, LA – 2023 – 10.1111/cas.15650
A correlative biomarker study and integrative prognostic model in chemotherapy-naive metastatic castration-resistant prostate cancer treated with enzalutamide – PROSTATE
Fernandez-Perez, MP; Perez-Navarro, E; Alonso-Gordoa, T; Conteduca, V; Font, A; Vazquez-Estevez, S; Gonzalez-del-Alba, A; Wetterskog, D; Antonarakis, ES; Mellado, B; Fernandez-Calvo, O; Mendez-Vidal, MJ; Climent, MA; Duran, I; Gallardo, E; Sanchez, AR; Santander, C; Saez, MI; Puente, J; Tudela, J; Martinez, A; Lopez-Andreo, MJ; Padilla, J; Lozano, R; Hervas, D; Luo, J; de Giorgi, U; Castellano, D; Attard, G; Grande, E; Gonzalez-Billalabeitia, E – 2023 – 10.1002/pros.24469
Dual neoadjuvant blockade plus chemotherapy versus monotherapy for the treatment of women with non-metastatic HER2-positive breast cancer: a systematic review and meta-analysis – CLINICAL & TRANSLATIONAL ONCOLOGY
Vazquez, JC; Antolin, S; Ruiz-Borrego, M; Servitja, S; Alba, E; Barnadas, A; Lluch, A; Martin, M; Rodriguez-Lescure, A; Sola, I; Bonfill, X; Urrutia, G; Sanchez-Rovira, P – 2023 – 10.1007/s12094-022-02998-2
Phase II trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/ CDKN2A – SIGNAL TRANSDUCTION AND TARGETED THERAPY
Martin-Broto, J; Martinez-Garcia, J; Moura, DS; Redondo, A; Gutierrez, A; Lopez-Pousa, A; Martinez-Trufero, J; Sevilla, I; Diaz-Beveridge, R; Solis-Hernandez, MP; Carnero, A; Perez, M; Marcilla, D; Garcia-Foncillas, J; Romero, P; Fernandez-Jara, J; Lopez-Lopez, D; Arribas, I; Hindi, N – 2023 – 10.1038/s41392-023-01661-8
A phase Ib/II study of galunisertib in combination with nivolumab in solid tumors and non-small cell lung cancer – BMC CANCER
Nadal, E; Saleh, M; Aix, SP; Ochoa-de-Olza, M; Patel, SP; Antonia, S; Zhao, YM; Gueorguieva, I; Man, MC; Estrem, ST; Liu, JA; Avsar, E; Lin, WH; Benhadji, KA; Gandhi, L; Guba, SC; Diaz, IA – 2023 – 10.1186/s12885-023-11153-1
Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin – NATURE COMMUNICATIONS
Capdevila, J; Hernando, J; Teule, A; Lopez, C; Garcia-Carbonero, R; Benavent, M; Custodio, A; Garcia-Alvarez, A; Cubillo, A; Alonso, V; Carmona-Bayonas, A; Alonso-Gordoa, T; Crespo, G; Jimenez-Fonseca, P; Blanco, M; Viudez, A; La Casta, A; Sevilla, I; Segura, A; Llanos, M; Landolfi, S; Nuciforo, P; Manzano, JL – 2023 – 10.1038/s41467-023-38611-5
Plasma short-chain fatty acid changes after bariatric surgery in patients with severe obesity – SURGERY FOR OBESITY AND RELATED DISEASES
Martinez-Sanchez, MA; Balaguer-Roman, A; Fernandez-Ruiz, VE; Almansa-Saura, S; Garcia-Zafra, V; Ferrer-Gomez, M; Frutos, MD; Queipo-Ortuno, MI; Ruiz-Alcaraz, AJ; Nunez-Sanchez, MA; Ramos-Molina, B – 2023 – 10.1016/j.soard.2022.12.041
A signature of circulating microRNAs predicts the response to treatment with FOLFIRI plus aflibercept in metastatic colorectal cancer patients – BIOMEDICINE & PHARMACOTHERAPY
Toledano-Fonseca, M; Gomez-Espana, MA; Elez, E; Gravalos, C; Garcia-Alfonso, P; Rodriguez, R; Losa, F; Diaz, IA; Grana, B; Valladares-Ayerbes, M; Garcia-Ortiz, MV; Polo, E; Salgado, M; Rivera, F; Safont, MJ; Salud, A; Ruiz-Casado, A; Tabernero, JM; Riesco, MC; Rodriguez-Ariza, A; Aranda, E – 2023 – 10.1016/j.biopha.2023.114272
Early Diagnosis of Oral Cancer and Lesions in Fanconi Anemia Patients: A Prospective and Longitudinal Study Using Saliva and Plasma – CANCERS
Errazquin, R; Carrasco, E; Del Marro, S; Suñol, A; Peral, J; Ortiz, J; Rubio, JC; Segrelles, C; Dueñas, M; Garrido-Aranda, A; Alvarez, M; Belendez, C; Balmaña, J; Garcia-Escudero, R – 2023 – 10.3390/cancers15061871
Real-World Outcomes in Patients with Metastatic Colorectal Cancer in Spain: The RWD-ACROSS Study – CANCERS
Pericay, C; Montes, AF; Orduña, VA; Declara, IM; Martínez, EA; Salas, NR; Torres, E; Lavín, DC; Alonso, RMR; Falcó, E; Oliva, JC; Cirera, L – 2023 – 10.3390/cancers15184603
ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA – GENOME MEDICINE
Huebner, A; Black, JRM; Sarno, F; Pazo, R; Juez, I; Medina, L; Garcia-Carbonero, R; Guillen, C; Feliu, J; Alonso, C; Arenillas, C; Moreno-Cardenas, AB; Verdaguer, H; Macarulla, T; Hidalgo, M; McGranahan, N; Toledo, RA – 2023 – 10.1186/s13073-023-01171-w
Epigenetic Marks as Predictors of Metabolic Response to Bariatric Surgery: Validation from an Epigenome Wide Association Study – INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Gutiérrez-Repiso, C; Cantarero-Cuenca, A; González-Jiménez, A; Linares-Pineda, T; Peña-Montero, N; Ocaña-Wilhelmi, L; Tinahones, FJ; Morcillo, S – 2023 – 10.3390/ijms241914778
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Members
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Researcher in ChargeSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Senior InvestigatorSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigador Asistencial ColaboradorSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigador posdoctorales y/o juniorSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Investigadores predoctorales y/o formaciónSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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Personal TécnicoSerá Investigador de este nivel los Investigadores Responsable que lideren un grupo de investigación del Instituto y sus Co-IR. Esta categoría puede incluir investigadores muy excepcionales en su disciplina.
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